DK364787D0 - 6- eller 7-methylenandrosta-1,4-dien-3,17-dion-derivater og fremgangsmaade til fremstilling deraf - Google Patents

6- eller 7-methylenandrosta-1,4-dien-3,17-dion-derivater og fremgangsmaade til fremstilling deraf

Info

Publication number: DK364787D0
Authority: DK; Denmark
Prior art keywords: methylenandrosta; diene; hydrogen; procedures; preparing
Prior art date: 1986-07-14

Application number

DK364787A

Other languages

English (en)

Other versions

DK364787A (da

Inventor

Franco Buzetti

Natale Barbugian

Paolo Lombardi

Salle Enerico Di

Original Assignee

Erba Farmitalia

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-07-14

Filing date

1987-07-13

Publication date

1987-07-13

1987-07-13 Application filed by Erba Farmitalia filed Critical Erba Farmitalia

1987-07-13 Publication of DK364787D0 publication Critical patent/DK364787D0/da

1988-01-15 Publication of DK364787A publication Critical patent/DK364787A/da

Links

PGEPQXVRDCMXHK-LPBINRMYSA-N (8r,9s,10r,13s,14s)-10,13-dimethyl-7-methylidene-6,8,9,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,17-dione Chemical class O=C1C=C[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3C(=C)CC2=C1 PGEPQXVRDCMXHK-LPBINRMYSA-N 0.000 title abstract 2
238000000034 method Methods 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 abstract 5
239000001257 hydrogen Substances 0.000 abstract 5
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical group FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
239000002246 antineoplastic agent Substances 0.000 abstract 1
229910052731 fluorine Chemical group 0.000 abstract 1
239000011737 fluorine Chemical group 0.000 abstract 1
229910052736 halogen Chemical group 0.000 abstract 1
150000002367 halogens Chemical group 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/008—Ketals at position 17
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK364787A 1986-07-14 1987-07-13 6- eller 7-methylenandrosta-1,4-dien-3,17-dion-derivater og fremgangsmaade til fremstilling deraf DK364787A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB868617107A GB8617107D0 (en)	1986-07-14	1986-07-14	6-/7-methylenandrosta-1 4-diene-3 17-dione derivatives

Publications (2)

Publication Number	Publication Date
DK364787D0 true DK364787D0 (da)	1987-07-13
DK364787A DK364787A (da)	1988-01-15

Family

ID=10601019

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK364787A DK364787A (da)	1986-07-14	1987-07-13	6- eller 7-methylenandrosta-1,4-dien-3,17-dion-derivater og fremgangsmaade til fremstilling deraf

Country Status (24)

Country	Link
US (1)	US4824830A (da)
EP (1)	EP0253591B1 (da)
JP (1)	JP2643943B2 (da)
CN (1)	CN87104750A (da)
AT (1)	ATE44282T1 (da)
AU (1)	AU589269B2 (da)
CA (1)	CA1309400C (da)
CS (1)	CS262695B2 (da)
DE (1)	DE3760277D1 (da)
DK (1)	DK364787A (da)
ES (1)	ES2010513B3 (da)
FI (1)	FI873052A7 (da)
GB (1)	GB8617107D0 (da)
GR (1)	GR3000085T3 (da)
HU (1)	HU196223B (da)
IL (1)	IL83132A (da)
MY (1)	MY100512A (da)
NO (1)	NO872892D0 (da)
NZ (1)	NZ221012A (da)
PH (1)	PH22994A (da)
PT (1)	PT85318B (da)
SU (1)	SU1549485A3 (da)
YU (1)	YU45827B (da)
ZA (1)	ZA875098B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5719448A (en) *	1989-03-07	1998-02-17	Seiko Epson Corporation	Bonding pad structures for semiconductor integrated circuits
US5227375A (en) *	1990-02-08	1993-07-13	Endorecherche, Inc.	Aromatase inhibitors
JP2602456B2 (ja) *	1990-04-12	1997-04-23	雪印乳業株式会社	子宮内膜症治療剤
CH683151A5 (de) *	1991-04-24	1994-01-31	Ciba Geigy Ag	Antikonzeption bei weiblichen Primaten ohne Beeinflussung des menstruellen Zyklus.
GB9217035D0 (en) *	1992-08-11	1992-09-23	Erba Carlo Spa	Androst-4-eno(4,5-b)pyrrole derivatives and process for their preparation
JPH07506120A (ja) *	1993-02-18	1995-07-06	フアルマシア・エ・アツプジヨン・エツセ・ピー・アー	フッ素化４−アミノアンドロスタジエノン誘導体及びその製造方法
GB9313420D0 (en) *	1993-06-29	1993-08-11	Erba Carlo Spa	Fluorinated 6-methylenandrosta-1,4-dien-3-one-derivatives and process for their preparations
FI109641B (fi) *	2000-03-10	2002-09-13	Nokia Corp	Mikrofonirakenne
US20040082557A1 (en) *	2001-01-26	2004-04-29	Wajszczuk Charles Paul	Methods for treating estrogen-dependent disorders
JP2004519490A (ja) *	2001-01-26	2004-07-02	フアルマシア・イタリア・エツセ・ピー・アー	エキセメスタンによるホルモン依存性異常症の組合せ治療方法
US20050101581A1 (en) *	2002-08-28	2005-05-12	Reading Christopher L.	Therapeutic treatment methods 2
ATE548375T1 (de) *	2004-01-16	2012-03-15	Cedarburg Pharmaceuticals Inc	Exemestan und zwischenprodukte davon und verfahren zu dessen herstellung
US20080275259A1 (en) *	2007-05-04	2008-11-06	Scinopharm Taiwan, Ltd	Process for preparing aromatase inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB929985A (da) *
US2744120A (en) *	1953-01-14	1956-05-01	Olin Mathieson	1-dehydrotestololactone
US4235893A (en) *	1978-05-08	1980-11-25	Brodie Angela M	Ester derivatives of 4-hydroxy-4-androstene-3,17-dione and a method for inhibiting estrogen biosynthesis
DE3322285A1 (de) *	1983-06-18	1984-12-20	Schering AG, 1000 Berlin und 4709 Bergkamen	1-alkyl-androsta-1,4-dien-3,17-dione, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate
DE3485093D1 (de) *	1984-12-28	1991-10-24	Ibm	Zuechtungsverfahren und vorrichtung zur herstellung von siliciumkristallen mit hohem und kontrolliertem kohlenstoffgehalt.
GB8517360D0 (en) *	1985-07-09	1985-08-14	Erba Farmitalia	Substituted androsta-1,4-diene-3,17-diones
JPH0718729B2 (ja) *	1990-06-11	1995-03-06	山武ハネウエル株式会社	ヒータ温度制御回路

1986
- 1986-07-14 GB GB868617107A patent/GB8617107D0/en active Pending
1987
- 1987-07-06 HU HU873038A patent/HU196223B/hu not_active IP Right Cessation
- 1987-07-07 PH PH35503A patent/PH22994A/en unknown
- 1987-07-07 US US07/070,685 patent/US4824830A/en not_active Expired - Fee Related
- 1987-07-08 IL IL83132A patent/IL83132A/xx unknown
- 1987-07-09 NZ NZ221012A patent/NZ221012A/xx unknown
- 1987-07-09 CA CA000541646A patent/CA1309400C/en not_active Expired - Lifetime
- 1987-07-09 AU AU75508/87A patent/AU589269B2/en not_active Ceased
- 1987-07-10 NO NO872892A patent/NO872892D0/no unknown
- 1987-07-10 YU YU129487A patent/YU45827B/sh unknown
- 1987-07-10 AT AT87306125T patent/ATE44282T1/de active
- 1987-07-10 ES ES87306125T patent/ES2010513B3/es not_active Expired
- 1987-07-10 DE DE8787306125T patent/DE3760277D1/de not_active Expired
- 1987-07-10 EP EP87306125A patent/EP0253591B1/en not_active Expired
- 1987-07-10 FI FI873052A patent/FI873052A7/fi not_active Application Discontinuation
- 1987-07-11 CN CN198787104750A patent/CN87104750A/zh active Pending
- 1987-07-13 ZA ZA875098A patent/ZA875098B/xx unknown
- 1987-07-13 PT PT85318A patent/PT85318B/pt not_active IP Right Cessation
- 1987-07-13 JP JP62174594A patent/JP2643943B2/ja not_active Expired - Lifetime
- 1987-07-13 DK DK364787A patent/DK364787A/da not_active Application Discontinuation
- 1987-07-13 SU SU874202950A patent/SU1549485A3/ru active
- 1987-07-14 CS CS875350A patent/CS262695B2/cs unknown
- 1987-07-14 MY MYPI87001007A patent/MY100512A/en unknown
1989
- 1989-06-29 GR GR89400089T patent/GR3000085T3/el unknown

Also Published As

Publication number	Publication date
PT85318B (pt)	1990-04-30
EP0253591A1 (en)	1988-01-20
ES2010513B3 (es)	1989-11-16
AU7550887A (en)	1988-01-21
YU45827B (sh)	1992-07-20
NZ221012A (en)	1989-05-29
US4824830A (en)	1989-04-25
FI873052L (fi)	1988-01-15
JPS6323895A (ja)	1988-02-01
PH22994A (en)	1989-02-24
JP2643943B2 (ja)	1997-08-25
YU129487A (en)	1988-10-31
AU589269B2 (en)	1989-10-05
PT85318A (en)	1987-08-01
DK364787A (da)	1988-01-15
GB8617107D0 (en)	1986-08-20
NO872892D0 (no)	1987-07-10
HU196223B (en)	1988-10-28
FI873052A7 (fi)	1988-01-15
FI873052A0 (fi)	1987-07-10
IL83132A0 (en)	1987-12-31
DE3760277D1 (en)	1989-08-03
GR3000085T3 (en)	1990-10-31
CN87104750A (zh)	1988-03-23
ZA875098B (en)	1988-03-30
HUT44038A (en)	1988-01-28
CS535087A2 (en)	1988-08-16
MY100512A (en)	1990-10-30
CA1309400C (en)	1992-10-27
SU1549485A3 (ru)	1990-03-07
IL83132A (en)	1992-01-15
CS262695B2 (en)	1989-03-14
ATE44282T1 (de)	1989-07-15
EP0253591B1 (en)	1989-06-28

Legal Events

Date	Code	Title	Description
1992-04-21	AHS	Application shelved for other reasons than non-payment

Publication	Publication Date	Title
DK364787D0 (da)	1987-07-13	6- eller 7-methylenandrosta-1,4-dien-3,17-dion-derivater og fremgangsmaade til fremstilling deraf
ES8802429A1 (es)	1988-06-01	Un procedimiento para la preparacion de androsta-1,4-dien-3,17-dionas
BG102701A (en)	1999-04-30	2-hetaroylcyclohexan-1,3-dions
ATE44748T1 (de)	1989-08-15	4-substituierte 6-alkylidene-androsten-3,17-dion- derivate und verfahren zu ihrer herstellung.
ATE98253T1 (de)	1993-12-15	Synthese von 6-methylenandrosta-1,4-dien-3,17dion-derivate.
DE3873862D1 (de)	1992-09-24	17-substituierte androsta-1,4-dien-3-on-derivate.
FI893901A0 (fi)	1989-08-18	Menetelmä tetrasyklisten masennuslääkkeiden valmistamiseksi
DE3661833D1 (de)	1989-02-23	Steroidic aromatase inhibitors