DK3704227T3 - Sammensætning og fremgangsmåde - Google Patents
Sammensætning og fremgangsmåde Download PDFInfo
- Publication number
- DK3704227T3 DK3704227T3 DK18874672.1T DK18874672T DK3704227T3 DK 3704227 T3 DK3704227 T3 DK 3704227T3 DK 18874672 T DK18874672 T DK 18874672T DK 3704227 T3 DK3704227 T3 DK 3704227T3
- Authority
- DK
- Denmark
- Prior art keywords
- composition
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/22—Urine; Urinary tract, e.g. kidney or bladder; Intraglomerular mesangial cells; Renal mesenchymal cells; Adrenal gland
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y70/00—Materials specially adapted for additive manufacturing
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0062—General methods for three-dimensional culture
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0684—Cells of the urinary tract or kidneys
- C12N5/0686—Kidney cells
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5014—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/26—Materials or treatment for tissue regeneration for kidney reconstruction
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y80/00—Products made by additive manufacturing
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/119—Other fibroblast growth factors, e.g. FGF-4, FGF-8, FGF-10
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/385—Hormones with nuclear receptors of the family of the retinoic acid recptor, e.g. RAR, RXR; Peroxisome proliferator-activated receptor [PPAR]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
- C12N2501/415—Wnt; Frizzeled
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/72—Transferases [EC 2.]
- C12N2501/727—Kinases (EC 2.7.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/999—Small molecules not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2513/00—3D culture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/70—Polysaccharides
- C12N2533/78—Cellulose
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Manufacturing & Machinery (AREA)
- Materials Engineering (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Developmental Biology & Embryology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Botany (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2017904424A AU2017904424A0 (en) | 2017-10-31 | Composition and method | |
| PCT/AU2018/051178 WO2019084612A1 (en) | 2017-10-31 | 2018-10-31 | Composition and method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3704227T3 true DK3704227T3 (da) | 2025-04-07 |
Family
ID=66331111
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK18874672.1T DK3704227T3 (da) | 2017-10-31 | 2018-10-31 | Sammensætning og fremgangsmåde |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US12188050B2 (da) |
| EP (1) | EP3704227B1 (da) |
| JP (2) | JP2021500929A (da) |
| KR (1) | KR102946635B1 (da) |
| CN (1) | CN111433351B (da) |
| AU (1) | AU2018360620B2 (da) |
| CA (1) | CA3079024A1 (da) |
| DK (1) | DK3704227T3 (da) |
| ES (1) | ES3024935T3 (da) |
| SG (1) | SG11202003790PA (da) |
| WO (1) | WO2019084612A1 (da) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020019023A1 (en) * | 2018-07-23 | 2020-01-30 | Murdoch Childrens Research Institute | Composition and method |
| WO2020053257A1 (en) * | 2018-09-11 | 2020-03-19 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Automated generation and analysis of organoids |
| US20230029554A1 (en) * | 2019-12-12 | 2023-02-02 | The Walter And Eliza Hall Institute Of Medecal Research | Organoid cultures |
| EP4243837A4 (en) * | 2020-11-13 | 2025-01-15 | Timothy A. Bertram | ENRICHED BIOACTIVE KIDNEY CELL POPULATIONS, PROPERTIES AND USES THEREOF |
| KR102574856B1 (ko) * | 2021-02-05 | 2023-09-07 | 연세대학교 산학협력단 | 신장 질환의 예방 또는 치료용 조성물 |
| JP7728088B2 (ja) * | 2021-02-26 | 2025-08-22 | 日機装株式会社 | 凍結された腎臓細胞の製造方法及び凍結された腎臓細胞 |
| CN113025569B (zh) * | 2021-03-26 | 2023-05-05 | 成都云测医学生物技术有限公司 | 人多能干细胞来源的间充质干细胞及其制备方法和应用 |
| CN113046309B (zh) * | 2021-03-26 | 2023-05-05 | 成都云测医学生物技术有限公司 | 悬浮培养脑类器官的培养基及其应用 |
| WO2022236144A1 (en) | 2021-05-06 | 2022-11-10 | Massachusetts Institute Of Technology | Ex vivo tissue explant and graft platform and uses thereof |
| CN113604539B (zh) * | 2021-08-06 | 2023-07-14 | 上海欧易生物医学科技有限公司 | 一种适用于单细胞测序的低温解离试剂盒及其应用 |
| US20240376435A1 (en) * | 2021-09-03 | 2024-11-14 | Otsuka Pharmaceutical Co., Ltd. | Kidney organoid and method for producing same |
| KR102593230B1 (ko) * | 2022-01-28 | 2023-10-25 | 가톨릭대학교 산학협력단 | Twist1 억제제를 유효성분으로 포함하는 신장 오가노이드 성숙도 향상용 조성물 |
| WO2024091043A1 (ko) * | 2022-10-26 | 2024-05-02 | 한국화학연구원 | 신장 근위 세뇨관 오가노이드, 신장암 오가노이드, 갑상선 오가노이드 또는 갑상선암 오가노이드, 이의 제조방법 및 이를 이용한 약물 평가 방법 |
| GB202308793D0 (en) | 2023-06-13 | 2023-07-26 | Astrazeneca Ab | Tissue regeneration |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7615374B2 (en) | 2007-09-25 | 2009-11-10 | Wisconsin Alumni Research Foundation | Generation of clonal mesenchymal progenitors and mesenchymal stem cell lines under serum-free conditions |
| EP3231869A1 (en) | 2008-06-13 | 2017-10-18 | Whitehead Institute for Biomedical Research | Programming and reprogramming of cells |
| WO2012054195A2 (en) | 2010-10-21 | 2012-04-26 | Organovo, Inc. | Devices, systems, and methods for the fabrication of tissue |
| AU2012308724A1 (en) | 2011-09-12 | 2014-04-24 | Organovo, Inc. | Platform for engineered implantable tissues and organs and methods of making the same |
| EP2712918B1 (en) * | 2012-09-28 | 2014-11-12 | TissUse GmbH | Multi-organ-chip with improved life time and homoeostasis |
| JP6677631B2 (ja) | 2013-03-13 | 2020-04-08 | ウイスコンシン アラムナイ リサーチ ファウンデーシヨンWisconsin Alumni Research Foundation | 定義された条件下におけるヒト多能性幹細胞の造血内皮分化のための方法及び材料 |
| SG11201510201PA (en) * | 2013-06-11 | 2016-01-28 | Univ Kyoto | Method for producing renal progenitor cells and drug comprising the same |
| RU2016100232A (ru) * | 2013-06-14 | 2017-07-17 | Дзе Юниверсити Оф Квинсленд | Почечные клетки-предшественники |
| KR20160068000A (ko) * | 2013-10-14 | 2016-06-14 | 아레스 트레이딩 에스.아. | 포유동물의 고성능 유가식 배양을 위한 신규 배지 |
| AU2014277667B2 (en) | 2014-12-15 | 2022-07-14 | The University Of Queensland | Differentiation of pluripotent stem cells to form renal organoids |
| WO2017041041A1 (en) * | 2015-09-03 | 2017-03-09 | The Brigham And Women's Hospital, Inc. | Three-dimensional differentiation of epiblast spheroids to kidney organoids models stage-specific epithelial physiology, morphogenesis, and disease |
| JP2018527007A (ja) * | 2015-09-17 | 2018-09-20 | ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッドThe Brigham and Women’s Hospital, Inc. | ヒト多能性幹細胞からネフロンを生成する方法 |
| WO2018207714A1 (ja) * | 2017-05-09 | 2018-11-15 | 公立大学法人名古屋市立大学 | 多能性幹細胞由来腸管オルガノイドの作製法 |
| WO2020019023A1 (en) * | 2018-07-23 | 2020-01-30 | Murdoch Childrens Research Institute | Composition and method |
-
2018
- 2018-10-31 DK DK18874672.1T patent/DK3704227T3/da active
- 2018-10-31 KR KR1020207012445A patent/KR102946635B1/ko active Active
- 2018-10-31 US US16/759,642 patent/US12188050B2/en active Active
- 2018-10-31 WO PCT/AU2018/051178 patent/WO2019084612A1/en not_active Ceased
- 2018-10-31 AU AU2018360620A patent/AU2018360620B2/en active Active
- 2018-10-31 CA CA3079024A patent/CA3079024A1/en active Pending
- 2018-10-31 EP EP18874672.1A patent/EP3704227B1/en active Active
- 2018-10-31 JP JP2020543656A patent/JP2021500929A/ja active Pending
- 2018-10-31 ES ES18874672T patent/ES3024935T3/es active Active
- 2018-10-31 SG SG11202003790PA patent/SG11202003790PA/en unknown
- 2018-10-31 CN CN201880070169.0A patent/CN111433351B/zh active Active
-
2023
- 2023-09-14 JP JP2023149208A patent/JP7729862B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP7729862B2 (ja) | 2025-08-26 |
| JP2023165023A (ja) | 2023-11-14 |
| AU2018360620A1 (en) | 2020-04-23 |
| JP2021500929A (ja) | 2021-01-14 |
| SG11202003790PA (en) | 2020-05-28 |
| US12188050B2 (en) | 2025-01-07 |
| WO2019084612A1 (en) | 2019-05-09 |
| US20200291361A1 (en) | 2020-09-17 |
| CA3079024A1 (en) | 2019-05-09 |
| EP3704227A4 (en) | 2021-07-28 |
| EP3704227A1 (en) | 2020-09-09 |
| AU2018360620B2 (en) | 2025-01-02 |
| KR102946635B1 (ko) | 2026-04-01 |
| CN111433351B (zh) | 2025-02-11 |
| CN111433351A (zh) | 2020-07-17 |
| ES3024935T3 (en) | 2025-06-05 |
| EP3704227B1 (en) | 2025-03-05 |
| KR20200086665A (ko) | 2020-07-17 |
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