MA50063A - Composés, compositions et procédés - Google Patents
Composés, compositions et procédésInfo
- Publication number
- MA50063A MA50063A MA050063A MA50063A MA50063A MA 50063 A MA50063 A MA 50063A MA 050063 A MA050063 A MA 050063A MA 50063 A MA50063 A MA 50063A MA 50063 A MA50063 A MA 50063A
- Authority
- MA
- Morocco
- Prior art keywords
- compositions
- compounds
- processes
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/14—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762553750P | 2017-09-01 | 2017-09-01 | |
| US201762609267P | 2017-12-21 | 2017-12-21 | |
| US201862634721P | 2018-02-23 | 2018-02-23 | |
| US201862697281P | 2018-07-12 | 2018-07-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA50063A true MA50063A (fr) | 2021-04-28 |
Family
ID=65526108
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA050063A MA50063A (fr) | 2017-09-01 | 2018-08-31 | Composés, compositions et procédés |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US12139478B2 (fr) |
| EP (2) | EP4248965A3 (fr) |
| JP (3) | JP7382308B2 (fr) |
| CN (1) | CN111201245B (fr) |
| CA (1) | CA3072057A1 (fr) |
| DK (1) | DK3676297T3 (fr) |
| ES (1) | ES2952994T3 (fr) |
| FI (1) | FI3676297T3 (fr) |
| HU (1) | HUE062446T2 (fr) |
| MA (1) | MA50063A (fr) |
| PL (1) | PL3676297T3 (fr) |
| PT (1) | PT3676297T (fr) |
| SI (1) | SI3676297T1 (fr) |
| TW (1) | TW201920129A (fr) |
| WO (1) | WO2019046779A1 (fr) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MA49858A (fr) | 2017-08-09 | 2021-04-28 | Denali Therapeutics Inc | Composés, compositions et procédés |
| DK3676297T3 (da) | 2017-09-01 | 2023-08-14 | Denali Therapeutics Inc | Forbindelser, sammensætninger og fremgangsmåder |
| CA3080971A1 (fr) | 2017-11-02 | 2019-05-09 | Calico Life Sciences Llc | Modulateurs de la voie de reponse integree au stress |
| EP3723762A4 (fr) | 2017-12-13 | 2021-12-08 | Praxis Biotech LLC | Inhibiteurs de la voie de réponse intégrée au stress |
| BR112020023115A2 (pt) | 2018-06-05 | 2021-02-02 | Praxis Biotech LLC | inibidores da via integrada de resposta a tensão |
| TWI832295B (zh) | 2018-10-11 | 2024-02-11 | 美商嘉來克生命科學有限責任公司 | 整合應激路徑之前藥調節劑 |
| MA54959A (fr) | 2019-02-13 | 2021-12-22 | Denali Therapeutics Inc | Composés, compositions et procédés |
| SG11202108552QA (en) | 2019-02-13 | 2021-09-29 | Denali Therapeutics Inc | Compounds, compositions and methods |
| IL287379B2 (en) * | 2019-04-23 | 2025-11-01 | Evotec Int Gmbh | Modulators of the integrated stress response pathway |
| AU2020262153B2 (en) * | 2019-04-23 | 2026-01-22 | Evotec International Gmbh | Modulators of the integrated stress response pathway |
| US20200347043A1 (en) * | 2019-04-30 | 2020-11-05 | Calico Life Sciences Llc | Modulators of the integrated stress pathway |
| CA3142748A1 (fr) | 2019-06-12 | 2020-12-17 | Praxis Biotech LLC | Modulateurs de la voie de reponse integree au stress |
| US20230125481A1 (en) | 2020-01-28 | 2023-04-27 | Evotec International Gmbh | Modulators of the integrated stress response pathway |
| EP4117780A1 (fr) * | 2020-03-11 | 2023-01-18 | Evotec International GmbH | Modulateurs de la voie de réponse au stress intégrée |
| PL4232154T3 (pl) | 2020-10-22 | 2025-02-24 | Evotec International Gmbh | Modulatory zintegrowanego szlaku odpowiedzi na stres |
| CA3195290A1 (fr) | 2020-10-22 | 2022-04-28 | Holly Victoria Atton | Modulateurs de la voie de reponse integree au stress |
| MX2023004677A (es) * | 2020-10-22 | 2023-05-24 | Evotec Int Gmbh | Moduladores de la via de respuesta integrada al estres. |
| CN116761803A (zh) * | 2020-10-22 | 2023-09-15 | 埃沃特克国际有限责任公司 | 整合应激反应途径的调节剂 |
| MX2023004870A (es) * | 2020-10-30 | 2023-05-11 | Calico Life Sciences Llc | Moduladores de la via integrada del estres. |
| CN116768877A (zh) * | 2022-05-30 | 2023-09-19 | 中国药科大学 | Isr抑制剂及其制备方法和应用 |
| TW202440081A (zh) * | 2023-03-14 | 2024-10-16 | 美商人福醫藥美國公司 | σ-1受體拮抗劑及其應用 |
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| FR2585572B3 (fr) | 1985-07-31 | 1987-12-31 | Hugelin Andre | Nouvelles compositions pharmaceutiques a base d'un sel de l'acide p. chlorophenoxyacetique destinees au traitement des neuropathies et assurant la regeneration nerveuse |
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| AR024077A1 (es) | 1999-05-25 | 2002-09-04 | Smithkline Beecham Corp | Compuestos antibacterianos |
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| CA2443108A1 (fr) | 2001-04-03 | 2002-10-17 | Merck & Co. Inc. | Antagonistes de nmda/nr2b nonaryl-heterocyclo amidyle n-substitues |
| JO2397B1 (en) | 2002-12-20 | 2007-06-17 | ميرك شارب اند دوم كوربوريشن | Terazol derivatives as beta-hydroxy steroid dihydrogenase-1 inhibitors |
| CN101068794B (zh) | 2004-09-02 | 2012-12-19 | 沃泰克斯药物股份有限公司 | 可用作离子通道调控剂的喹唑啉 |
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| WO2013058448A1 (fr) | 2011-10-20 | 2013-04-25 | 한국해양연구원 | Gènes de medaka marin répondant à l'exposition à des substances chimiques perturbant le système endocrinien et procédé destiné à diagnostiquer une pollution d'un écosystème aquatique les utilisant |
| EP2814321B1 (fr) | 2012-02-14 | 2018-09-26 | Syngenta Participations AG | Dérivés de cis(hétéro)arylcyclopropylcarboxamide utiles en tant que nematicides |
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| KR102243637B1 (ko) | 2013-03-14 | 2021-04-26 | 리커리엄 아이피 홀딩스, 엘엘씨 | 바이사이클릭 진통 화합물 |
| CA2904794C (fr) | 2013-03-15 | 2021-11-23 | Peter Walter | Modulateurs de la voie eif2 alpha |
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| TW201808903A (zh) | 2016-05-05 | 2018-03-16 | 嘉來克生命科學有限責任公司 | 整合應激途徑之調節劑 |
| US10851053B2 (en) | 2016-06-08 | 2020-12-01 | Glaxosmithkline Intellectual Property Development Limited | Chemical compounds |
| KR20190015748A (ko) | 2016-06-08 | 2019-02-14 | 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 | Atf4 경로 억제제로서의 화학적 화합물 |
| TWI749024B (zh) | 2016-07-06 | 2021-12-11 | 美商艾克奎斯特有限責任公司 | 化合物及其於降低尿酸位準之用途 |
| JOP20190072A1 (ar) | 2016-10-13 | 2019-04-07 | Glaxosmithkline Ip Dev Ltd | مشتقات 1، 3 سيكلوبوتان ثنائي الاستبدال أو آزيتيدين كمثبطات للإنزيم المخلق للبروستاجلاندين d المكون للدم |
| US10093664B2 (en) | 2016-12-08 | 2018-10-09 | Board Of Regents, The University Of Texas System | Bicyclo[1.1.1]pentane inhibitors of dual leucine zipper (DLK) kinase for the treatment of disease |
| WO2018225093A1 (fr) | 2017-06-07 | 2018-12-13 | Glaxosmithkline Intellectual Property Development Limited | Composés chimiques utilisés comme inhibiteurs de la voie atf4 |
| KR102615098B1 (ko) | 2017-06-09 | 2023-12-18 | 브리스톨-마이어스 스큅 컴퍼니 | 시클로프로필 우레아 포르밀 펩티드 2 수용체 및 포르밀 펩티드 1 수용체 효능제 |
| CA3068395A1 (fr) | 2017-07-03 | 2019-01-10 | Glaxosmithkline Intellectual Property Development Limited | Derives de 2-(4-chlorophenoxy)-n-((1-(2-(4-chlorophenoxy)ethynazetidine-3-yl)methyl)acetamide et composes apparentes servant d'inhibiteurs d'atf4 pour le traitement du cancer et d'autres maladies |
| BR112020000122A2 (pt) | 2017-07-03 | 2020-07-07 | Glaxosmithkline Intellectual Property Development Limited | derivados da n-(3-(2-(4-clorofenóxi)acetamido)biciclo[1.1.1] pentan-1-il)-2-ciclobutano-1-carboxamida e compostos relacionados como inibidores do atf4 para tratamento contra o câncer e outras doenças |
| MA49858A (fr) | 2017-08-09 | 2021-04-28 | Denali Therapeutics Inc | Composés, compositions et procédés |
| DK3676297T3 (da) | 2017-09-01 | 2023-08-14 | Denali Therapeutics Inc | Forbindelser, sammensætninger og fremgangsmåder |
| WO2019054430A1 (fr) | 2017-09-14 | 2019-03-21 | 第一三共株式会社 | Composé amide ayant un hétérocycle aromatique |
| CA3080808A1 (fr) | 2017-11-02 | 2019-05-09 | Calico Life Sciences Llc | Modulateurs de la voie de reponse integree au stress |
| CN112218869A (zh) | 2017-11-02 | 2021-01-12 | 卡里科生命科学有限责任公司 | 整合应激通路的调节剂 |
| UY37957A (es) | 2017-11-02 | 2019-05-31 | Abbvie Inc | Moduladores de la vía de estrés integrada |
| UY37956A (es) | 2017-11-02 | 2019-05-31 | Abbvie Inc | Moduladores de la vía de estrés integrada |
| CA3080964A1 (fr) | 2017-11-02 | 2019-05-09 | Calico Life Sciences Llc | Modulateurs de la voie de reponse integree au stress |
| UY37958A (es) | 2017-11-02 | 2019-05-31 | Abbvie Inc | Moduladores de la vía de estrés integrada |
| CA3080971A1 (fr) | 2017-11-02 | 2019-05-09 | Calico Life Sciences Llc | Modulateurs de la voie de reponse integree au stress |
| KR20200092332A (ko) | 2017-11-02 | 2020-08-03 | 칼리코 라이프 사이언시스 엘엘씨 | 통합된 스트레스 경로의 조절제 |
| SG11202004009TA (en) | 2017-11-02 | 2020-05-28 | Calico Life Sciences Llc | Modulators of the integrated stress pathway |
| EP3723762A4 (fr) | 2017-12-13 | 2021-12-08 | Praxis Biotech LLC | Inhibiteurs de la voie de réponse intégrée au stress |
| WO2019183589A1 (fr) | 2018-03-23 | 2019-09-26 | Denali Therapeutics Inc. | Modulateurs du facteur 2 d'initiation eucaryote |
| WO2019193540A1 (fr) | 2018-04-06 | 2019-10-10 | Glaxosmithkline Intellectual Property Development Limited | Dérivés hétéroaryles de formule (i) utilisés en tant qu'inhibiteurs d'atf4 |
| WO2019193541A1 (fr) | 2018-04-06 | 2019-10-10 | Glaxosmithkline Intellectual Property Development Limited | Dérivés de cycle aromatiques bicycliques de formule (i) utilisés en tant qu'inhibiteurs d'atf4 |
| EP3820843A1 (fr) | 2018-07-09 | 2021-05-19 | GlaxoSmithKline Intellectual Property Development Limited | Composés chimiques |
| WO2020031107A1 (fr) | 2018-08-08 | 2020-02-13 | Glaxosmithkline Intellectual Property Development Limited | Composés chimiques |
| TWI832295B (zh) | 2018-10-11 | 2024-02-11 | 美商嘉來克生命科學有限責任公司 | 整合應激路徑之前藥調節劑 |
| SG11202108552QA (en) | 2019-02-13 | 2021-09-29 | Denali Therapeutics Inc | Compounds, compositions and methods |
| MA54959A (fr) | 2019-02-13 | 2021-12-22 | Denali Therapeutics Inc | Composés, compositions et procédés |
| US20220177456A1 (en) | 2019-03-06 | 2022-06-09 | Denali Therapeutics Inc. | Compounds, compositions and methods |
| IL287379B2 (en) | 2019-04-23 | 2025-11-01 | Evotec Int Gmbh | Modulators of the integrated stress response pathway |
| US20200347043A1 (en) | 2019-04-30 | 2020-11-05 | Calico Life Sciences Llc | Modulators of the integrated stress pathway |
| KR20220016467A (ko) | 2019-04-30 | 2022-02-09 | 칼리코 라이프 사이언시스 엘엘씨 | 통합된 스트레스 경로의 조절인자로서 치환된 사이클로알킬 |
| US20230125481A1 (en) | 2020-01-28 | 2023-04-27 | Evotec International Gmbh | Modulators of the integrated stress response pathway |
| CR20230254A (es) | 2020-12-18 | 2023-07-26 | Denali Therapeutics Inc | Formas sólidas de un compuesto |
| KR20250028345A (ko) | 2022-06-23 | 2025-02-28 | 데날리 테라퓨틱스 인크. | 진핵생물 개시 인자 2b의 조절제를 제조하는 공정 |
-
2018
- 2018-08-31 DK DK18850713.1T patent/DK3676297T3/da active
- 2018-08-31 US US16/643,168 patent/US12139478B2/en active Active
- 2018-08-31 EP EP23173466.6A patent/EP4248965A3/fr active Pending
- 2018-08-31 SI SI201830964T patent/SI3676297T1/sl unknown
- 2018-08-31 PT PT188507131T patent/PT3676297T/pt unknown
- 2018-08-31 CN CN201880063335.4A patent/CN111201245B/zh active Active
- 2018-08-31 MA MA050063A patent/MA50063A/fr unknown
- 2018-08-31 ES ES18850713T patent/ES2952994T3/es active Active
- 2018-08-31 EP EP18850713.1A patent/EP3676297B1/fr active Active
- 2018-08-31 PL PL18850713.1T patent/PL3676297T3/pl unknown
- 2018-08-31 JP JP2020511347A patent/JP7382308B2/ja active Active
- 2018-08-31 CA CA3072057A patent/CA3072057A1/fr active Pending
- 2018-08-31 FI FIEP18850713.1T patent/FI3676297T3/fi active
- 2018-08-31 WO PCT/US2018/049197 patent/WO2019046779A1/fr not_active Ceased
- 2018-08-31 TW TW107130678A patent/TW201920129A/zh unknown
- 2018-08-31 HU HUE18850713A patent/HUE062446T2/hu unknown
-
2023
- 2023-02-28 JP JP2023030214A patent/JP2023060020A/ja active Pending
-
2024
- 2024-04-08 JP JP2024062313A patent/JP2024086819A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN111201245A (zh) | 2020-05-26 |
| JP2020532506A (ja) | 2020-11-12 |
| CA3072057A1 (fr) | 2019-03-07 |
| HUE062446T2 (hu) | 2023-11-28 |
| EP3676297A1 (fr) | 2020-07-08 |
| JP2024086819A (ja) | 2024-06-28 |
| JP7382308B2 (ja) | 2023-11-16 |
| US20200331900A1 (en) | 2020-10-22 |
| ES2952994T3 (es) | 2023-11-07 |
| DK3676297T3 (da) | 2023-08-14 |
| WO2019046779A1 (fr) | 2019-03-07 |
| SI3676297T1 (sl) | 2023-12-29 |
| PT3676297T (pt) | 2023-08-29 |
| EP3676297A4 (fr) | 2021-04-28 |
| EP3676297B1 (fr) | 2023-05-17 |
| CN111201245B (zh) | 2024-04-05 |
| PL3676297T3 (pl) | 2023-12-11 |
| US12139478B2 (en) | 2024-11-12 |
| TW201920129A (zh) | 2019-06-01 |
| EP4248965A3 (fr) | 2023-11-22 |
| FI3676297T3 (fi) | 2023-08-08 |
| EP4248965A2 (fr) | 2023-09-27 |
| JP2023060020A (ja) | 2023-04-27 |
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