DK3700940T3 - Funktionaliseret hyaluronsyre eller et derivat deraf i behandling af inflammatoriske tilstande - Google Patents

Funktionaliseret hyaluronsyre eller et derivat deraf i behandling af inflammatoriske tilstande Download PDF

Info

Publication number: DK3700940T3
Authority: DK; Denmark
Prior art keywords: derivative; treatment; hyaluronic acid; inflammatory conditions; functionalized hyaluronic
Prior art date: 2017-10-26

Application number

DK18804408.5T

Other languages

English (en)

Inventor

Giulio Bianchini

Lanfranco Callegaro

Original Assignee

Jointherapeutics S R L

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2017-10-26

Filing date

2018-10-24

Publication date

2022-02-21

2018-10-24 Application filed by Jointherapeutics S R L filed Critical Jointherapeutics S R L

2022-02-21 Application granted granted Critical

2022-02-21 Publication of DK3700940T3 publication Critical patent/DK3700940T3/da

Links

KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title 1
229920002674 hyaluronan Polymers 0.000 title 1
229960003160 hyaluronic acid Drugs 0.000 title 1
230000004968 inflammatory condition Effects 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/20—Polysaccharides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Dermatology (AREA)
Epidemiology (AREA)
Immunology (AREA)
Molecular Biology (AREA)
Transplantation (AREA)
Oral & Maxillofacial Surgery (AREA)
Rheumatology (AREA)
Materials Engineering (AREA)
Polymers & Plastics (AREA)
Biochemistry (AREA)
Dispersion Chemistry (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Pain & Pain Management (AREA)
Gastroenterology & Hepatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Materials For Medical Uses (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

DK18804408.5T 2017-10-26 2018-10-24 Funktionaliseret hyaluronsyre eller et derivat deraf i behandling af inflammatoriske tilstande DK3700940T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT102017000122135A IT201700122135A1 (it)	2017-10-26	2017-10-26	Acido ialuronico funzionalizzato o suo derivato nel trattamento di stati infiammatori
PCT/IB2018/058297 WO2019082097A1 (en)	2017-10-26	2018-10-24	FUNCTIONALIZED HYALURONIC ACID OR A DERIVATIVE THEREOF IN THE TREATMENT OF INFLAMMATORY CONDITIONS

Publications (1)

Publication Number	Publication Date
DK3700940T3 true DK3700940T3 (da)	2022-02-21

Family

ID=61526960

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK18804408.5T DK3700940T3 (da)	2017-10-26	2018-10-24	Funktionaliseret hyaluronsyre eller et derivat deraf i behandling af inflammatoriske tilstande

Country Status (13)

Country	Link
US (1)	US11203649B2 (da)
EP (1)	EP3700940B1 (da)
JP (1)	JP7277452B2 (da)
KR (1)	KR102688006B1 (da)
CN (1)	CN111247174B (da)
CA (1)	CA3078901A1 (da)
DK (1)	DK3700940T3 (da)
ES (1)	ES2906599T3 (da)
IL (1)	IL274089B2 (da)
IT (1)	IT201700122135A1 (da)
PL (1)	PL3700940T3 (da)
PT (1)	PT3700940T (da)
WO (1)	WO2019082097A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA3135919A1 (en) *	2019-04-19	2020-10-22	Jointherapeutics Srl	Crosslinked polymer of functionalized hyaluronic acid and its use in the treatment of inflammatory states
WO2022236585A1 (zh) *	2021-05-10	2022-11-17	傅毓秀	玻尿酸用于制备治疗肺纤维化药剂的用途
CN113754795B (zh) *	2021-10-19	2023-03-10	澳门大学	磺酸化透明质酸类化合物、其制备方法及其应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4851521A (en) *	1985-07-08	1989-07-25	Fidia, S.P.A.	Esters of hyaluronic acid
IT1219587B (it) *	1988-05-13	1990-05-18	Fidia Farmaceutici	Polisaccaridi carbossiilici autoreticolati
ATE229038T1 (de)	1997-04-04	2002-12-15	Fidia Advanced Biopolymers Srl	N-sulfatierte hyaluronsäureverbindungen, ihre derivate und verfahren zu ihrer herstellung
ITPD980169A1 (it) *	1998-07-06	2000-01-06	Fidia Advanced Biopolymers Srl	Ammidi dell'acido ialuronico e dei suoi derivati e processo per la loro preparazione.
US6756363B1 (en) *	2000-11-17	2004-06-29	Wound Healing Of Oklahoma, Inc.	Solutions and films of glycated chitosan
US20060134119A1 (en) *	2003-01-24	2006-06-22	Mitsuomi Hirashima	Drugs containing galectin 9
EP2402754B2 (en) *	2006-03-06	2023-07-26	Amunix Operating Inc.	Unstructured recombinant polymers and uses thereof
LU91414B1 (fr) *	2008-02-01	2009-08-03	Fidia Farmaceutici	Amides d'acide hyaluronique, derives de ce dernieret leurs procede de preparation
ITRM20080636A1 (it) *	2008-11-28	2010-05-29	Univ Palermo	Procedimento per la produzione di derivati funzionalizzati dell acido ialuronico e relativi idrogeli.
GB201214736D0 (en) *	2012-08-17	2012-10-03	Isis Innovation	Inflammation imaging and therapy
KR102130864B1 (ko) *	2012-09-05	2020-07-08	추가이 세이야쿠 가부시키가이샤	아미노산 및 스테릴기가 도입된 히알루론산 유도체
FR3033498B1 (fr) *	2015-03-12	2018-03-23	L'oreal	Procede de protection et de reparation des fibres keratiniques a partir de polysaccharide oxyde et de (poly)saccharide a groupe amine
CN106467563B (zh) *	2015-08-21	2019-08-06	北京大学	硫酸软骨素四糖的合成方法及其中间体化合物

2017
- 2017-10-26 IT IT102017000122135A patent/IT201700122135A1/it unknown
2018
- 2018-10-24 CN CN201880068662.9A patent/CN111247174B/zh active Active
- 2018-10-24 KR KR1020207013301A patent/KR102688006B1/ko active Active
- 2018-10-24 EP EP18804408.5A patent/EP3700940B1/en active Active
- 2018-10-24 US US16/757,864 patent/US11203649B2/en active Active
- 2018-10-24 JP JP2020522074A patent/JP7277452B2/ja active Active
- 2018-10-24 IL IL274089A patent/IL274089B2/en unknown
- 2018-10-24 WO PCT/IB2018/058297 patent/WO2019082097A1/en not_active Ceased
- 2018-10-24 ES ES18804408T patent/ES2906599T3/es active Active
- 2018-10-24 PL PL18804408T patent/PL3700940T3/pl unknown
- 2018-10-24 CA CA3078901A patent/CA3078901A1/en active Pending
- 2018-10-24 PT PT188044085T patent/PT3700940T/pt unknown
- 2018-10-24 DK DK18804408.5T patent/DK3700940T3/da active

Also Published As

Publication number	Publication date
US20210189017A1 (en)	2021-06-24
KR102688006B1 (ko)	2024-07-25
CN111247174B (zh)	2022-07-22
CN111247174A (zh)	2020-06-05
IL274089B2 (en)	2024-10-01
WO2019082097A1 (en)	2019-05-02
RU2020113879A (ru)	2021-11-26
PT3700940T (pt)	2022-02-14
EP3700940A1 (en)	2020-09-02
KR20200077528A (ko)	2020-06-30
US11203649B2 (en)	2021-12-21
IL274089A (en)	2020-06-30
IT201700122135A1 (it)	2019-04-26
CA3078901A1 (en)	2019-05-02
EP3700940B1 (en)	2021-12-15
IL274089B1 (en)	2024-06-01
PL3700940T3 (pl)	2022-03-21
JP7277452B2 (ja)	2023-05-19
ES2906599T3 (es)	2022-04-19
JP2021500436A (ja)	2021-01-07

Publication	Publication Date	Title
SI3169328T1 (sl)	2022-11-30	Derivati kinolina za zdravljenje vnetnih bolezni
EP3398564A4 (en)	2019-08-14	LUMINOUS STENT
DK3315593T3 (da)	2020-03-16	Detergentsammensætning omfattende et kationisk derivat af en polysaccharid
DK3663292T3 (da)	2021-10-25	Diphenylmethan-derivat i krystallinsk form
EP3247317C0 (en)	2024-10-16	Stent
EP3161143C0 (en)	2024-10-23	PRODUCTION OF OLIGOSACCHARIDES
DK3107500T3 (da)	2021-12-06	Fleksibel kommissurramme
DK3149152T3 (da)	2022-01-24	Forøgelse af lipidproduktion og optimering af lipidsammensætning
DK3102213T3 (da)	2020-05-04	Farmaceutiske sammensætninger til behandlingen af inflammatoriske lidelser
DK3689609T3 (da)	2022-07-04	Transplantatstillads til bruskreparation og en fremgangsmåde til fremstilling af samme
SI3398378T1 (sl)	2021-04-30	Postopek za vzpostavitev zveze med gostovanjem
EP3563802A4 (en)	2020-10-14	LUMINAL STENT
DK3380313T3 (da)	2019-09-02	Forbedringer vedrørende fremstillingen af vindmøllevinger
EP3563810A4 (en)	2020-08-19	ABSORBABLE STENT
FI20155406A7 (fi)	2016-11-30	Moolimassasäädelty selluloosa
DK3274159T3 (da)	2019-08-05	Reperation af vindmøllekomponenter
EP3320883A4 (en)	2019-03-20	INTRAVASCULAR STENT
IL249995A0 (en)	2017-03-30	Aluminophosphate glass composition
EP3778653C0 (en)	2025-07-09	NEW REACTIVE ALGINIC ACID DERIVATIVES
FR3020570B1 (fr)	2017-07-21	Association d'un acide hyaluronique et d'un polysaccharide sulfate
EP3632376C0 (en)	2024-03-06	SELF-CURVING STENT
LT3445743T (lt)	2021-09-27	Aminorūgšties darinio provaistas
HUE055778T2 (hu)	2021-12-28	Oligo-ovulációval összefüggõ májzsírosodás kezelése
DK4299264T3 (da)	2026-02-02	Fjernelse af glaspanel
BR112017001006A2 (pt)	2017-12-19	recuperação de ácido acético da acetilação de madeira