DK3729055T3 - Fremgangsmåde og sensor til detektering af tilstedeværelse eller fravær af en kontaminant - Google Patents
Fremgangsmåde og sensor til detektering af tilstedeværelse eller fravær af en kontaminantInfo
- Publication number
- DK3729055T3 DK3729055T3 DK18836809.6T DK18836809T DK3729055T3 DK 3729055 T3 DK3729055 T3 DK 3729055T3 DK 18836809 T DK18836809 T DK 18836809T DK 3729055 T3 DK3729055 T3 DK 3729055T3
- Authority
- DK
- Denmark
- Prior art keywords
- contaminant
- absence
- detecting
- sensor
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/15—Preventing contamination of the components of the optical system or obstruction of the light path
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
- G01N21/85—Investigating moving fluids or granular solids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/15—Preventing contamination of the components of the optical system or obstruction of the light path
- G01N2021/155—Monitoring cleanness of window, lens, or other parts
- G01N2021/157—Monitoring by optical means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6432—Quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N2021/7769—Measurement method of reaction-produced change in sensor
- G01N2021/7786—Fluorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/06—Illumination; Optics
- G01N2201/061—Sources
- G01N2201/06113—Coherent sources; lasers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/06—Illumination; Optics
- G01N2201/062—LED's
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Plasma & Fusion (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Ecology (AREA)
- Optics & Photonics (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA201700741 | 2017-12-22 | ||
| PCT/EP2018/084526 WO2019121220A1 (en) | 2017-12-22 | 2018-12-12 | Method and sensor for detecting presence or absence of a contaminant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3729055T3 true DK3729055T3 (da) | 2025-12-15 |
Family
ID=65138950
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK18836809.6T DK3729055T3 (da) | 2017-12-22 | 2018-12-12 | Fremgangsmåde og sensor til detektering af tilstedeværelse eller fravær af en kontaminant |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US11268905B2 (da) |
| EP (2) | EP4682515A3 (da) |
| JP (1) | JP7337069B2 (da) |
| KR (1) | KR102423160B1 (da) |
| CN (1) | CN111512143B (da) |
| DK (1) | DK3729055T3 (da) |
| WO (1) | WO2019121220A1 (da) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12180581B2 (en) | 2017-09-18 | 2024-12-31 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes |
| US11709155B2 (en) | 2017-09-18 | 2023-07-25 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes |
| US11709156B2 (en) | 2017-09-18 | 2023-07-25 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved analytical analysis |
| US12181452B2 (en) | 2017-09-18 | 2024-12-31 | Waters Technologies Corporation | Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes |
| US11918936B2 (en) | 2020-01-17 | 2024-03-05 | Waters Technologies Corporation | Performance and dynamic range for oligonucleotide bioanalysis through reduction of non specific binding |
| EP4208076A4 (en) * | 2020-09-01 | 2024-10-02 | The General Hospital Corporation | SYSTEMS AND METHODS FOR MONITORING AN ANALYTE OR PATIENT-RELATED PARAMETER |
| US12352734B2 (en) | 2020-09-24 | 2025-07-08 | Waters Technologies Corporation | Chromatographic hardware improvements for separation of reactive molecules |
| CN117255939A (zh) * | 2021-02-10 | 2023-12-19 | 罗伯特·博世有限公司 | 用于分析物检测的光学系统 |
| WO2022173432A1 (en) * | 2021-02-10 | 2022-08-18 | Aquaeasy Pte. Ltd. | Optical system for analyte detection |
| IT202100007418A1 (it) * | 2021-03-26 | 2022-09-26 | Datamed S R L | Dispositivo e metodo per misurare un parametro del sangue |
| CN117603632B (zh) * | 2024-01-23 | 2024-04-09 | 上海精珅新材料有限公司 | 一种含有uv增粘胶水的胶带制备方法 |
| WO2025225211A1 (ja) * | 2024-04-23 | 2025-10-30 | 株式会社日立ハイテク | 自動分析装置、及び自動分析装置におけるled光源の判定方法 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5030420A (en) * | 1982-12-23 | 1991-07-09 | University Of Virginia Alumni Patents Foundation | Apparatus for oxygen determination |
| CA1261717A (en) | 1982-12-23 | 1989-09-26 | John R. Bacon | Method and apparatus for oxygen determination |
| US4895156A (en) * | 1986-07-02 | 1990-01-23 | Schulze John E | Sensor system using fluorometric decay measurements |
| US5564419A (en) | 1987-11-25 | 1996-10-15 | Radiometer A/S | Method of photometric in vitro determination of the content of oxygen in a blood sample |
| US4910406A (en) | 1988-03-23 | 1990-03-20 | E. I. Du Pont De Nemours And Company | Method for detecting the presence of contaminants in a reusable plastic food or beverage container |
| AT407303B (de) * | 1995-07-17 | 2001-02-26 | Avl Verbrennungskraft Messtech | Verfahren zur qualitätskontrolle eines portablen analysensystems sowie flüssigkeit zur durchführung des verfahrens |
| JP2003504622A (ja) | 1999-07-08 | 2003-02-04 | ラジオメーター・メディカル・アクティーゼルスカブ | 親水性マトリックス材料を含んでなるセンサー |
| ATE421685T1 (de) | 1999-10-29 | 2009-02-15 | Radiometer Medical Aps | Verfahren und vorrichtung zum nachweis einer gasblase in einer flüssigkeit |
| AT414172B (de) | 2004-09-02 | 2006-09-15 | Hoffmann La Roche | Verfahren zur detektion einer gasblase in einer wässrigen flüssigkeit |
| US20060171845A1 (en) * | 2005-01-31 | 2006-08-03 | Dakota Technologies, Inc. | Sensors for measuring analytes |
| EP1722223A1 (en) * | 2005-05-10 | 2006-11-15 | Eidgenossisch Technische Hochschule Zürich | Metal oxide membrane with a gas-selective compound |
| US20110105869A1 (en) * | 2006-01-04 | 2011-05-05 | The Trustees Of The University Of Pennsylvania | Sensor for Internal Monitoring of Tissue O2 and/or pH/CO2 In Vivo |
| EP1973503B1 (en) * | 2006-01-04 | 2013-09-25 | The Trustees of the University of Pennsylvania | Oxygen sensor for internal monitoring of tissue oxygen in vivo |
| EP1986007A1 (en) | 2007-04-27 | 2008-10-29 | Radiometer Medical ApS | A sensor assembly for body fluids |
| EP1985994A1 (en) | 2007-04-27 | 2008-10-29 | Radiometer Medical ApS | An optical sensor system |
| JP2009222429A (ja) * | 2008-03-13 | 2009-10-01 | Nippon Sheet Glass Co Ltd | 光学式酸素センサーチップ、その製造方法及びそれを用いた光学式酸素センサー |
| JP2009281794A (ja) * | 2008-05-20 | 2009-12-03 | Tokyo Univ Of Science | 気泡または液滴の非接触処理方法および非接触処理装置 |
| SE533680C2 (sv) | 2009-04-07 | 2010-11-30 | Per Ola Andersson | Metod och anordning för detektering av läkemedel i ett prov |
| EP2246692B1 (de) | 2009-04-30 | 2012-02-08 | F. Hoffmann-La Roche AG | Verfahren zur Detektion von Verunreinigungen einer optischen Messküvette |
| JP5277082B2 (ja) * | 2009-06-15 | 2013-08-28 | 株式会社日立ハイテクノロジーズ | 蛍光分析方法 |
| JP2011185841A (ja) | 2010-03-10 | 2011-09-22 | Fujifilm Corp | 粒子分析装置および粒子分析方法 |
| EP2738544B1 (en) | 2012-11-30 | 2016-09-28 | Nxp B.V. | Fouling layer detection on an environmental sensor |
| US9709499B1 (en) * | 2013-09-12 | 2017-07-18 | Innovative Scientific Solutions, Inc. | Measurement of oxygen |
| DK3394615T3 (da) | 2015-12-22 | 2023-11-27 | Radiometer Medical Aps | Fremgangsmåde til påvisning af tilstedeværelse eller fravær af et koagel i en væskeprøveanalysator |
| EP3394614B1 (en) | 2015-12-22 | 2022-03-02 | Radiometer Medical ApS | Method of detecting the presence or absence of a clot in a liquid sample analyzer |
| US20170226571A1 (en) * | 2016-01-25 | 2017-08-10 | Trutag Technologies, Inc. | System and Method for Highly-Multiplexed, Label-Free Detection of Analytes Using Optical Tags |
| GB201621481D0 (en) * | 2016-12-16 | 2017-02-01 | Univ Oxford Innovation Ltd | Optical sensor |
-
2018
- 2018-12-12 JP JP2020534910A patent/JP7337069B2/ja active Active
- 2018-12-12 US US16/955,183 patent/US11268905B2/en active Active
- 2018-12-12 DK DK18836809.6T patent/DK3729055T3/da active
- 2018-12-12 EP EP25212709.7A patent/EP4682515A3/en active Pending
- 2018-12-12 EP EP18836809.6A patent/EP3729055B1/en active Active
- 2018-12-12 KR KR1020207021120A patent/KR102423160B1/ko active Active
- 2018-12-12 CN CN201880083009.XA patent/CN111512143B/zh active Active
- 2018-12-12 WO PCT/EP2018/084526 patent/WO2019121220A1/en not_active Ceased
-
2022
- 2022-02-01 US US17/649,564 patent/US11860095B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN111512143A (zh) | 2020-08-07 |
| US11268905B2 (en) | 2022-03-08 |
| US20220187207A1 (en) | 2022-06-16 |
| EP3729055B1 (en) | 2025-11-05 |
| EP3729055A1 (en) | 2020-10-28 |
| WO2019121220A1 (en) | 2019-06-27 |
| JP7337069B2 (ja) | 2023-09-01 |
| US20200309699A1 (en) | 2020-10-01 |
| EP4682515A2 (en) | 2026-01-21 |
| KR20200096845A (ko) | 2020-08-13 |
| JP2021507257A (ja) | 2021-02-22 |
| US11860095B2 (en) | 2024-01-02 |
| KR102423160B1 (ko) | 2022-07-19 |
| CN111512143B (zh) | 2023-11-14 |
| EP4682515A3 (en) | 2026-04-08 |
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