DK3729055T3 - Fremgangsmåde og sensor til detektering af tilstedeværelse eller fravær af en kontaminant - Google Patents

Fremgangsmåde og sensor til detektering af tilstedeværelse eller fravær af en kontaminant

Info

Publication number
DK3729055T3
DK3729055T3 DK18836809.6T DK18836809T DK3729055T3 DK 3729055 T3 DK3729055 T3 DK 3729055T3 DK 18836809 T DK18836809 T DK 18836809T DK 3729055 T3 DK3729055 T3 DK 3729055T3
Authority
DK
Denmark
Prior art keywords
contaminant
absence
detecting
sensor
Prior art date
Application number
DK18836809.6T
Other languages
English (en)
Inventor
Michael Taagaard
Peter Frischauf
Flemming Aas
Original Assignee
Radiometer Medical Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Radiometer Medical Aps filed Critical Radiometer Medical Aps
Application granted granted Critical
Publication of DK3729055T3 publication Critical patent/DK3729055T3/da

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/15Preventing contamination of the components of the optical system or obstruction of the light path
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6408Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84Systems specially adapted for particular applications
    • G01N21/85Investigating moving fluids or granular solids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/15Preventing contamination of the components of the optical system or obstruction of the light path
    • G01N2021/155Monitoring cleanness of window, lens, or other parts
    • G01N2021/157Monitoring by optical means
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6432Quenching
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7769Measurement method of reaction-produced change in sensor
    • G01N2021/7786Fluorescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/06Illumination; Optics
    • G01N2201/061Sources
    • G01N2201/06113Coherent sources; lasers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/06Illumination; Optics
    • G01N2201/062LED's
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plasma & Fusion (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Ecology (AREA)
  • Optics & Photonics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK18836809.6T 2017-12-22 2018-12-12 Fremgangsmåde og sensor til detektering af tilstedeværelse eller fravær af en kontaminant DK3729055T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA201700741 2017-12-22
PCT/EP2018/084526 WO2019121220A1 (en) 2017-12-22 2018-12-12 Method and sensor for detecting presence or absence of a contaminant

Publications (1)

Publication Number Publication Date
DK3729055T3 true DK3729055T3 (da) 2025-12-15

Family

ID=65138950

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18836809.6T DK3729055T3 (da) 2017-12-22 2018-12-12 Fremgangsmåde og sensor til detektering af tilstedeværelse eller fravær af en kontaminant

Country Status (7)

Country Link
US (2) US11268905B2 (da)
EP (2) EP4682515A3 (da)
JP (1) JP7337069B2 (da)
KR (1) KR102423160B1 (da)
CN (1) CN111512143B (da)
DK (1) DK3729055T3 (da)
WO (1) WO2019121220A1 (da)

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US12180581B2 (en) 2017-09-18 2024-12-31 Waters Technologies Corporation Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes
US11709155B2 (en) 2017-09-18 2023-07-25 Waters Technologies Corporation Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes
US11709156B2 (en) 2017-09-18 2023-07-25 Waters Technologies Corporation Use of vapor deposition coated flow paths for improved analytical analysis
US12181452B2 (en) 2017-09-18 2024-12-31 Waters Technologies Corporation Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes
US11918936B2 (en) 2020-01-17 2024-03-05 Waters Technologies Corporation Performance and dynamic range for oligonucleotide bioanalysis through reduction of non specific binding
EP4208076A4 (en) * 2020-09-01 2024-10-02 The General Hospital Corporation SYSTEMS AND METHODS FOR MONITORING AN ANALYTE OR PATIENT-RELATED PARAMETER
US12352734B2 (en) 2020-09-24 2025-07-08 Waters Technologies Corporation Chromatographic hardware improvements for separation of reactive molecules
CN117255939A (zh) * 2021-02-10 2023-12-19 罗伯特·博世有限公司 用于分析物检测的光学系统
WO2022173432A1 (en) * 2021-02-10 2022-08-18 Aquaeasy Pte. Ltd. Optical system for analyte detection
IT202100007418A1 (it) * 2021-03-26 2022-09-26 Datamed S R L Dispositivo e metodo per misurare un parametro del sangue
CN117603632B (zh) * 2024-01-23 2024-04-09 上海精珅新材料有限公司 一种含有uv增粘胶水的胶带制备方法
WO2025225211A1 (ja) * 2024-04-23 2025-10-30 株式会社日立ハイテク 自動分析装置、及び自動分析装置におけるled光源の判定方法

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US5030420A (en) * 1982-12-23 1991-07-09 University Of Virginia Alumni Patents Foundation Apparatus for oxygen determination
CA1261717A (en) 1982-12-23 1989-09-26 John R. Bacon Method and apparatus for oxygen determination
US4895156A (en) * 1986-07-02 1990-01-23 Schulze John E Sensor system using fluorometric decay measurements
US5564419A (en) 1987-11-25 1996-10-15 Radiometer A/S Method of photometric in vitro determination of the content of oxygen in a blood sample
US4910406A (en) 1988-03-23 1990-03-20 E. I. Du Pont De Nemours And Company Method for detecting the presence of contaminants in a reusable plastic food or beverage container
AT407303B (de) * 1995-07-17 2001-02-26 Avl Verbrennungskraft Messtech Verfahren zur qualitätskontrolle eines portablen analysensystems sowie flüssigkeit zur durchführung des verfahrens
JP2003504622A (ja) 1999-07-08 2003-02-04 ラジオメーター・メディカル・アクティーゼルスカブ 親水性マトリックス材料を含んでなるセンサー
ATE421685T1 (de) 1999-10-29 2009-02-15 Radiometer Medical Aps Verfahren und vorrichtung zum nachweis einer gasblase in einer flüssigkeit
AT414172B (de) 2004-09-02 2006-09-15 Hoffmann La Roche Verfahren zur detektion einer gasblase in einer wässrigen flüssigkeit
US20060171845A1 (en) * 2005-01-31 2006-08-03 Dakota Technologies, Inc. Sensors for measuring analytes
EP1722223A1 (en) * 2005-05-10 2006-11-15 Eidgenossisch Technische Hochschule Zürich Metal oxide membrane with a gas-selective compound
US20110105869A1 (en) * 2006-01-04 2011-05-05 The Trustees Of The University Of Pennsylvania Sensor for Internal Monitoring of Tissue O2 and/or pH/CO2 In Vivo
EP1973503B1 (en) * 2006-01-04 2013-09-25 The Trustees of the University of Pennsylvania Oxygen sensor for internal monitoring of tissue oxygen in vivo
EP1986007A1 (en) 2007-04-27 2008-10-29 Radiometer Medical ApS A sensor assembly for body fluids
EP1985994A1 (en) 2007-04-27 2008-10-29 Radiometer Medical ApS An optical sensor system
JP2009222429A (ja) * 2008-03-13 2009-10-01 Nippon Sheet Glass Co Ltd 光学式酸素センサーチップ、その製造方法及びそれを用いた光学式酸素センサー
JP2009281794A (ja) * 2008-05-20 2009-12-03 Tokyo Univ Of Science 気泡または液滴の非接触処理方法および非接触処理装置
SE533680C2 (sv) 2009-04-07 2010-11-30 Per Ola Andersson Metod och anordning för detektering av läkemedel i ett prov
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Also Published As

Publication number Publication date
CN111512143A (zh) 2020-08-07
US11268905B2 (en) 2022-03-08
US20220187207A1 (en) 2022-06-16
EP3729055B1 (en) 2025-11-05
EP3729055A1 (en) 2020-10-28
WO2019121220A1 (en) 2019-06-27
JP7337069B2 (ja) 2023-09-01
US20200309699A1 (en) 2020-10-01
EP4682515A2 (en) 2026-01-21
KR20200096845A (ko) 2020-08-13
JP2021507257A (ja) 2021-02-22
US11860095B2 (en) 2024-01-02
KR102423160B1 (ko) 2022-07-19
CN111512143B (zh) 2023-11-14
EP4682515A3 (en) 2026-04-08

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