DK376986A - Di-tert-butylphenol-forbindelser og fremgangsmaade til fremstilling heraf - Google Patents
Di-tert-butylphenol-forbindelser og fremgangsmaade til fremstilling heraf Download PDFInfo
- Publication number
- DK376986A DK376986A DK376986A DK376986A DK376986A DK 376986 A DK376986 A DK 376986A DK 376986 A DK376986 A DK 376986A DK 376986 A DK376986 A DK 376986A DK 376986 A DK376986 A DK 376986A
- Authority
- DK
- Denmark
- Prior art keywords
- tert
- procedures
- preparing
- butylphenol compounds
- butylphenol
- Prior art date
Links
- SKDGWNHUETZZCS-UHFFFAOYSA-N 2,3-ditert-butylphenol Chemical class CC(C)(C)C1=CC=CC(O)=C1C(C)(C)C SKDGWNHUETZZCS-UHFFFAOYSA-N 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/14—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/16—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/36—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
- C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
- C07D327/04—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76416085A | 1985-08-09 | 1985-08-09 | |
| US76416085 | 1985-08-09 | ||
| US86948886A | 1986-06-02 | 1986-06-02 | |
| US86948886 | 1986-06-02 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK376986D0 DK376986D0 (da) | 1986-08-07 |
| DK376986A true DK376986A (da) | 1987-02-10 |
| DK169324B1 DK169324B1 (da) | 1994-10-10 |
Family
ID=27117408
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK376986A DK169324B1 (da) | 1985-08-09 | 1986-08-07 | Di-tert-butylphenol-forbindelser, anvendelse af disse til fremstilling af farmaceutiske formuleringer, farmaceutiske formuleringer indeholdende forbindelserne samt fremgangsmåde til fremstilling af forbindelserne |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP0211670B1 (da) |
| JP (1) | JPH0625182B2 (da) |
| KR (1) | KR870000889B1 (da) |
| CN (1) | CN1014891B (da) |
| AR (1) | AR243173A1 (da) |
| AU (1) | AU590312B2 (da) |
| CA (1) | CA1285572C (da) |
| CY (1) | CY1619A (da) |
| DE (1) | DE3670951D1 (da) |
| DK (1) | DK169324B1 (da) |
| ES (1) | ES2001075A6 (da) |
| GR (1) | GR862081B (da) |
| HK (1) | HK94791A (da) |
| HU (1) | HU196192B (da) |
| IE (1) | IE58718B1 (da) |
| IL (1) | IL79648A (da) |
| LV (1) | LV10866B (da) |
| MX (1) | MX9203108A (da) |
| MY (1) | MY102365A (da) |
| NZ (1) | NZ217126A (da) |
| PH (1) | PH24517A (da) |
| PT (1) | PT83152B (da) |
| SG (1) | SG80391G (da) |
| SU (1) | SU1516012A3 (da) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8512163D0 (en) * | 1985-05-14 | 1985-06-19 | Fujisawa Pharmaceutical Co | Oxothiazolidine compound |
| US5356917A (en) * | 1985-08-09 | 1994-10-18 | Eli Lilly And Company | Aryl-substituted rhodanine derivatives |
| US5691367A (en) * | 1985-08-09 | 1997-11-25 | Eli Lilly And Company | Aryl-substituted rhodanine derivatives |
| US4897406A (en) * | 1987-11-13 | 1990-01-30 | Nisshin Flour Milling Co., Ltd. | Rhodanine derivatives and pharmaceutical compositions |
| US5306822A (en) * | 1988-05-25 | 1994-04-26 | Warner-Lambert Company | Arylmethylenyl derivatives of oxazolidinone |
| US5208250A (en) * | 1988-05-25 | 1993-05-04 | Warner-Lambert Company | Known and selected novel arylmethylenyl derivatives of thiazolidinones, imidazolidinones and oxazolidinones useful as antiallergy agents and anti-inflammatory agents |
| IE62214B1 (en) * | 1988-05-25 | 1995-01-11 | Warner Lambert Co | Arylmethylenyl derivatives of thiazolidinones, imidazolidinones and oxazolidinones useful as antiallergy agents and antiinflammatory agents |
| NZ231534A (en) * | 1988-11-29 | 1992-02-25 | Warner Lambert Co | 3,5-di-t-butyl-4-hydroxyphenyl-triazoles, oxadiazoles and thiadiazoles; anti-inflammatory compositions |
| ES2088965T3 (es) * | 1989-04-07 | 1996-10-01 | Lilly Co Eli | Derivados de rodanina aril-sustituidos. |
| US5216002A (en) * | 1989-12-21 | 1993-06-01 | Eli Lilly And Company | Method of treating inflammatory bowel disease |
| IL108962A (en) * | 1989-12-21 | 1996-12-05 | Lilly Co Eli | Use of hydroxybenzyl substituted sulfur containing heterocyclic derivatives a process for their preparation and pharmaceutical compositions containing them |
| US5143928A (en) * | 1990-03-27 | 1992-09-01 | Warner-Lambert Company | 3,5-di-tertiarybutyl-4-hydroxyphenylmethylene derivatives of 2-substituted thiazolidinones, oxazolidinones, and imidazolidinones as antiinflammatory agents |
| EP0526598B1 (en) * | 1990-04-27 | 1996-12-18 | Orion-Yhtymà Oy | New pharmacologically active catechol derivatives |
| ATE157355T1 (de) * | 1991-01-21 | 1997-09-15 | Shionogi & Co | 3-benzyliden-1-carbamoyl-2-pyrrolidon-analoga |
| US5158966A (en) * | 1991-02-22 | 1992-10-27 | The University Of Colorado Foundation, Inc. | Method of treating type i diabetes |
| US5143929A (en) * | 1991-05-09 | 1992-09-01 | Warner-Lambert Company | 2-substituted thiazolidinone, oxazolidinone, and imidazolidinone derivatives of fenamates as antiinflammatory agents |
| EP0915090A1 (en) * | 1992-09-10 | 1999-05-12 | Eli Lilly And Company | Compounds useful as hypoglycemic agents and for treating Alzheimer's disease |
| ATE135697T1 (de) * | 1992-10-28 | 1996-04-15 | Shionogi & Co | Benzylidenderivate |
| ATE196464T1 (de) * | 1993-06-23 | 2000-10-15 | Chugai Pharmaceutical Co Ltd | Benzol-derivate, verwendbar für ischämische erkrankungen |
| US6251928B1 (en) * | 1994-03-16 | 2001-06-26 | Eli Lilly And Company | Treatment of alzheimer's disease employing inhibitors of cathepsin D |
| US5476865A (en) * | 1994-07-06 | 1995-12-19 | Eli Lilly And Company | Methods of inhibiting bone loss |
| KR19980701588A (ko) * | 1995-01-23 | 1998-05-15 | 피터 쥐. 스트링거 | 다발성 경화증의 치료 방법(Method for Treating Multiple Sclerosis) |
| DK0761657T3 (da) * | 1995-09-07 | 2000-08-14 | Lilly Co Eli | Fremgangsmåde til fremstilling af benzylsubstituerede rhodaninderivater |
| NZ332763A (en) * | 1996-07-11 | 2000-07-28 | Warner Lambert Co | Treating and preventing neurodegenerative disorders by administering a thiazolidinone |
| US6005142A (en) * | 1996-09-03 | 1999-12-21 | Eli Lilly And Company | Process for preparing benzyl-substituted rhodanine derivatives |
| US6063799A (en) * | 1996-09-03 | 2000-05-16 | Eli Lilly And Company | Alternate crystal form of Tazofelone |
| WO2000018748A1 (en) * | 1998-09-30 | 2000-04-06 | Roche Diagnostics Gmbh | Rhodanine derivatives for the treatment and prevention of metabolic bone disorders |
| AU2002953533A0 (en) * | 2002-12-24 | 2003-01-16 | Arthron Limited | Fc receptor modulating compounds and compositions |
| DE202006018406U1 (de) | 2006-12-05 | 2008-04-10 | Seda S.P.A. | Verpackung |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1038050B (de) * | 1955-11-17 | 1958-09-04 | Farmaceutici Italia S A Soc | Verfahren zur Herstellung von 5-(3', 4'-Dioxybenzyliden)-Derivaten heterocyclischer Verbindungen |
| JPS5740478A (en) * | 1980-08-22 | 1982-03-06 | Ono Pharmaceut Co Ltd | Rhodanine derivative, its preparation and aldose reductase inhibitor containing rhodanine derivative |
| JPS57130950A (en) * | 1981-02-05 | 1982-08-13 | Kanegafuchi Chem Ind Co Ltd | 3,5-di-tert-butyl-4-hydroxystyrene derivative and anti- inflammatory, analgesic, antipyretic agent and inhibitor for blood platelet aggregation |
| JPS5879944A (ja) * | 1981-11-09 | 1983-05-13 | Kanegafuchi Chem Ind Co Ltd | ３，５−ジ・タ−シヤリ−・ブチルスチレン誘導体及び抗炎症、鎮痛、解熱剤並びに血小板凝集阻害剤 |
| US4636516A (en) * | 1981-02-19 | 1987-01-13 | Yamanouchi Pharmaceutical Co., Ltd. | 3,5-di-tert-butyl-4-hydroxyphenyl-substituted heterocyclic compounds |
-
1986
- 1986-08-06 IL IL79648A patent/IL79648A/xx not_active IP Right Cessation
- 1986-08-06 PT PT83152A patent/PT83152B/pt not_active IP Right Cessation
- 1986-08-06 CA CA000515379A patent/CA1285572C/en not_active Expired - Lifetime
- 1986-08-06 GR GR862081A patent/GR862081B/el unknown
- 1986-08-07 AU AU60972/86A patent/AU590312B2/en not_active Ceased
- 1986-08-07 DK DK376986A patent/DK169324B1/da not_active IP Right Cessation
- 1986-08-07 NZ NZ217126A patent/NZ217126A/xx unknown
- 1986-08-07 PH PH34111A patent/PH24517A/en unknown
- 1986-08-08 KR KR1019860006534A patent/KR870000889B1/ko not_active Expired
- 1986-08-08 ES ES8600951A patent/ES2001075A6/es not_active Expired
- 1986-08-08 SU SU864027906A patent/SU1516012A3/ru active
- 1986-08-08 AR AR86304842A patent/AR243173A1/es active
- 1986-08-08 CN CN86105036A patent/CN1014891B/zh not_active Expired
- 1986-08-08 IE IE213786A patent/IE58718B1/en not_active IP Right Cessation
- 1986-08-08 EP EP86306134A patent/EP0211670B1/en not_active Expired - Lifetime
- 1986-08-08 HU HU863516A patent/HU196192B/hu not_active IP Right Cessation
- 1986-08-08 JP JP61187645A patent/JPH0625182B2/ja not_active Expired - Fee Related
- 1986-08-08 DE DE8686306134T patent/DE3670951D1/de not_active Expired - Lifetime
-
1987
- 1987-09-22 MY MYPI87001858A patent/MY102365A/en unknown
-
1991
- 1991-10-04 SG SG803/91A patent/SG80391G/en unknown
- 1991-11-21 HK HK947/91A patent/HK94791A/en not_active IP Right Cessation
-
1992
- 1992-06-22 MX MX9203108A patent/MX9203108A/es unknown
- 1992-07-10 CY CY1619A patent/CY1619A/xx unknown
-
1993
- 1993-06-08 LV LVP-93-523A patent/LV10866B/lv unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0211670A2 (en) | 1987-02-25 |
| EP0211670B1 (en) | 1990-05-09 |
| DE3670951D1 (de) | 1990-06-13 |
| MY102365A (en) | 1992-06-17 |
| DK376986D0 (da) | 1986-08-07 |
| KR870000889B1 (ko) | 1987-05-02 |
| IE58718B1 (en) | 1993-11-03 |
| PH24517A (en) | 1990-07-18 |
| CN1014891B (zh) | 1991-11-27 |
| SU1516012A3 (ru) | 1989-10-15 |
| DK169324B1 (da) | 1994-10-10 |
| GR862081B (en) | 1986-12-24 |
| AU590312B2 (en) | 1989-11-02 |
| PT83152B (pt) | 1989-03-30 |
| MX9203108A (es) | 1992-07-01 |
| LV10866A (lv) | 1995-10-20 |
| IL79648A0 (en) | 1986-11-30 |
| NZ217126A (en) | 1989-01-27 |
| ES2001075A6 (es) | 1988-04-16 |
| CN86105036A (zh) | 1987-02-04 |
| HUT42765A (en) | 1987-08-28 |
| CY1619A (en) | 1992-07-10 |
| HK94791A (en) | 1991-11-29 |
| PT83152A (en) | 1986-09-01 |
| IL79648A (en) | 1991-12-12 |
| JPH0625182B2 (ja) | 1994-04-06 |
| LV10866B (en) | 1996-04-20 |
| SG80391G (en) | 1991-11-15 |
| AR243173A1 (es) | 1993-07-30 |
| EP0211670A3 (en) | 1987-05-06 |
| CA1285572C (en) | 1991-07-02 |
| HU196192B (en) | 1988-10-28 |
| JPS6242977A (ja) | 1987-02-24 |
| AU6097286A (en) | 1987-02-12 |
| KR870002109A (ko) | 1987-03-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PBP | Patent lapsed |
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