DK385388A - Anvendelse af 5ht-3-antagonister - Google Patents

Anvendelse af 5ht-3-antagonister

Info

Publication number: DK385388A
Authority: DK; Denmark
Prior art keywords: antagonists
Prior art date: 1987-07-11

Application number

DK385388A

Other languages

Danish (da)

English (en)

Other versions

DK385388D0 (da

Inventor

Assunta Imperato

Dietmar Roemer

Original Assignee

Sandoz Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-07-11

Filing date

1988-07-08

Publication date

1989-01-12

1988-07-08 Application filed by Sandoz Ag filed Critical Sandoz Ag

1988-07-08 Publication of DK385388D0 publication Critical patent/DK385388D0/da

1989-01-12 Publication of DK385388A publication Critical patent/DK385388A/da

Links

239000003369 serotonin 5-HT3 receptor antagonist Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Psychiatry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Addiction (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK385388A 1987-07-11 1988-07-08 Anvendelse af 5ht-3-antagonister DK385388A (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
DE3722959		1987-07-11
DE3735719		1987-10-22
CH451087		1987-11-19

Publications (2)

Publication Number	Publication Date
DK385388D0 DK385388D0 (da)	1988-07-08
DK385388A true DK385388A (da)	1989-01-12

Family

ID=27174878

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK385388A DK385388A (da)	1987-07-11	1988-07-08	Anvendelse af 5ht-3-antagonister

Country Status (18)

Country	Link
US (1)	US5039680A (de)
EP (1)	EP0302008A3 (de)
JP (1)	JPS6431729A (de)
KR (1)	KR890001537A (de)
AT (1)	AT401615B (de)
AU (3)	AU618008B2 (de)
BE (1)	BE1004835A5 (de)
DE (1)	DE3822792C2 (de)
DK (1)	DK385388A (de)
FR (1)	FR2617713A1 (de)
GB (2)	GB2206788B (de)
HU (1)	HU206042B (de)
IT (1)	IT1226632B (de)
MY (1)	MY103536A (de)
NL (1)	NL8801733A (de)
PH (1)	PH27002A (de)
PT (1)	PT87958B (de)
SE (1)	SE8802570L (de)

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US5166341A (en) *	1988-07-29	1992-11-24	Dainippon Pharmaceutical Co., Ltd.	6-amino-1,4-hexahydro-1H-diazepine derivatives
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GB8820650D0 (en) *	1988-09-01	1988-10-05	Glaxo Group Ltd	Medicaments
US4999382A (en) *	1988-10-26	1991-03-12	Massachusetts Institute Of Technology	Compositions for treating tobacco withdrawal symptoms and methods for their use
US5276050A (en) *	1989-08-01	1994-01-04	Glaxo Group Limited	Medicaments
CA2112487C (en) *	1991-06-26	2003-04-15	James W. Young	Method and compositions for treating emesis, nausea and other disorders using optically pure r(+) ondansetron
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US20040092511A1 (en) *	1999-12-10	2004-05-13	Billstein Stephan Anthony	Pharmaceutical combinations and their use in treating gastrointestinal and abdominal viscera disorders
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BR0212123A (pt) *	2001-08-24	2004-07-20	Upjohn Co	7-aza[2.2.1]biciclo-heptanos substituìdos com arila para o tratamento de doenças
WO2003018585A1 (en)	2001-08-24	2003-03-06	Pharmacia & Upjohn Company	Substituted-heteroaryl-7-aza[2.2.1]bicycloheptanes for the treatment of disease
EP1425286B1 (de) *	2001-09-12	2007-02-28	Pharmacia & Upjohn Company LLC	Substituierte 7-aza-[2.2.1]bicycloheptane für die behandlung von krankheiten
EP1432707B1 (de)	2001-10-02	2012-03-28	Pharmacia & Upjohn Company LLC	Azabicyclisch- substituierte annelierte heteroaryl-verbinungen für die behandlung von krankheiten
US6849620B2 (en)	2001-10-26	2005-02-01	Pfizer Inc	N-(azabicyclo moieties)-substituted hetero-bicyclic aromatic compounds for the treatment of disease
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US6951868B2 (en)	2001-11-09	2005-10-04	Pfizer Inc.	Azabicyclic-phenyl-fused-heterocyclic compounds for treatment of disease
DK1472225T3 (da)	2002-02-01	2010-08-09	Euro Celtique Sa	2-Piperazinpyridiner, som er anvendelige til behandling af smerte
JP2005522456A (ja)	2002-02-15	2005-07-28	ファルマシア・アンド・アップジョン・カンパニー・エルエルシー	Ｃｎｓ関連障害治療のためのアザビシクロ置換ベンゾイルアミドおよびチオアミド
BR0307782A (pt) *	2002-02-19	2005-01-04	Upjohn Co	Compostos azabiciclo para o tratamento de doença
US6858613B2 (en) *	2002-02-19	2005-02-22	Pfizer Inc.	Fused bicyclic-N-bridged-heteroaromatic carboxamides for the treatment of disease
WO2003072578A1 (en) *	2002-02-20	2003-09-04	Pharmacia & Upjohn Company	Azabicyclic compounds with alfa7 nicotinic acetylcholine receptor activity
US6974818B2 (en) *	2002-03-01	2005-12-13	Euro-Celtique S.A.	1,2,5-thiadiazol-3-YL-piperazine therapeutic agents useful for treating pain
US6864261B2 (en) *	2002-05-02	2005-03-08	Euro-Celtique S.A.	Therapeutic agents useful for treating pain
ES2300613T3 (es) *	2002-06-28	2008-06-16	Euro-Celtique S.A.	Derivados terapeuticos de piperacina utiles para tratar el dolor.
US7262194B2 (en) *	2002-07-26	2007-08-28	Euro-Celtique S.A.	Therapeutic agents useful for treating pain
US20080081834A1 (en)	2002-07-31	2008-04-03	Lippa Arnold S	Methods and compositions employing bicifadine for treating disability or functional impairment associated with acute pain, chronic pain, or neuropathic disorders
US7176198B2 (en) *	2002-08-01	2007-02-13	Pfizer Inc.	1H-pyrazole and 1H-pyrrole-azabicyclic compounds for the treatment of disease
US7157462B2 (en)	2002-09-24	2007-01-02	Euro-Celtique S.A.	Therapeutic agents useful for treating pain
US20040127501A1 (en) *	2002-09-24	2004-07-01	Zhengming Chen	Therapeutic agents useful for treating pain
CA2503786A1 (en) *	2002-11-01	2004-05-13	Pharmacia & Upjohn Company Llc	Compounds having both alpha7 nicotinic agonist activity and 5ht, antagonist activity for treatment of cns diseases
US7582635B2 (en) *	2002-12-24	2009-09-01	Purdue Pharma, L.P.	Therapeutic agents useful for treating pain
MY142655A (en) *	2003-06-12	2010-12-15	Euro Celtique Sa	Therapeutic agents useful for treating pain
SI1641775T1 (sl) *	2003-07-03	2009-08-31	Euro Celtique Sa	2-piridin alkinski derivati, uporabni za zdravljenje bolečine
EP2080757A1 (de) *	2003-07-24	2009-07-22	Euro-Celtique S.A.	Zur Behandlung oder Vorbeugung von Schmerzen geeignete Heteroaryl-Tetrahydropiperidyl-Verbindungen
BRPI0412808A (pt) *	2003-07-24	2006-09-26	Euro Celtique Sa	compostos de piperidina e composições farmacêuticas contendo os mesmos
PL1867644T3 (pl)	2003-07-24	2009-10-30	Euro Celtique Sa	Związki heteroarylo-tetrahydropiperydylowe przydatne w leczeniu lub zapobieganiu bólu
SI1942106T1 (sl)	2003-08-01	2012-01-31	Euro Celtique Sa	Terapevtska sredstva, uporabna za zdravljenje bolečine
DE602004017481D1 (de) *	2003-09-22	2008-12-11	Euro Celtique Sa	Zur behandlung von schmerzen geeignete therapeutische mittel
PT2017276E (pt)	2003-09-22	2011-04-05	Euro Celtique Sa	Compostos de fenilcarboxamida úteis para o tratamento da dor
CN1902178A (zh) *	2003-12-30	2007-01-24	欧洲凯尔特公司	用于治疗疼痛的哌嗪
US20070043100A1 (en)	2005-08-16	2007-02-22	Hagen Eric J	Novel polymorphs of azabicyclohexane
US20060100263A1 (en) *	2004-11-05	2006-05-11	Anthony Basile	Antipyretic compositions and methods
AU2006275870B2 (en)	2005-07-27	2013-01-10	Otsuka America Pharmaceutical, Inc.	Novel 1-aryl-3-azabicyclo[3.1.0]hexanes: preparation and use to treat neuropsychiatric disorders
US20080045725A1 (en) *	2006-04-28	2008-02-21	Murry Jerry A	Process For The Synthesis of (+) And (-)-1-(3,4-Dichlorophenyl)-3-Azabicyclo[3.1.0]Hexane
US8138377B2 (en) *	2006-11-07	2012-03-20	Dov Pharmaceutical, Inc.	Arylbicyclo[3.1.0]hexylamines and methods and compositions for their preparation and use
EP2479173A1 (de) *	2007-04-27	2012-07-25	Purdue Pharma LP	Zur Behandlung von Schmerzen geeignete therapeutische Mittel
US9133159B2 (en)	2007-06-06	2015-09-15	Neurovance, Inc.	1-heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments
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US8697722B2 (en) *	2007-11-02	2014-04-15	Sri International	Nicotinic acetylcholine receptor modulators
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US9980973B2 (en)	2012-10-19	2018-05-29	Astex Therapeutics Limited	Bicyclic heterocycle compounds and their uses in therapy
GB201218850D0 (en)	2012-10-19	2012-12-05	Astex Therapeutics Ltd	Bicyclic heterocycle compounds and their uses in therapy
GB201218864D0 (en)	2012-10-19	2012-12-05	Astex Therapeutics Ltd	Bicyclic heterocycle compounds and their uses in therapy
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WO2015092420A1 (en)	2013-12-20	2015-06-25	Astex Therapeutics Limited	Bicyclic heterocycle compounds and their uses in therapy

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FR2531083B1 (fr) *	1982-06-29	1986-11-28	Sandoz Sa	Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments
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1988
- 1988-07-06 DE DE3822792A patent/DE3822792C2/de not_active Expired - Fee Related
- 1988-07-07 EP EP19880810470 patent/EP0302008A3/de not_active Withdrawn
- 1988-07-08 AT AT0177688A patent/AT401615B/de not_active IP Right Cessation
- 1988-07-08 FR FR8809350A patent/FR2617713A1/fr active Granted
- 1988-07-08 NL NL8801733A patent/NL8801733A/nl not_active Application Discontinuation
- 1988-07-08 HU HU883610A patent/HU206042B/hu not_active IP Right Cessation
- 1988-07-08 PT PT87958A patent/PT87958B/pt not_active IP Right Cessation
- 1988-07-08 MY MYPI88000755A patent/MY103536A/en unknown
- 1988-07-08 GB GB8816298A patent/GB2206788B/en not_active Expired - Lifetime
- 1988-07-08 DK DK385388A patent/DK385388A/da not_active Application Discontinuation
- 1988-07-08 SE SE8802570A patent/SE8802570L/xx not_active Application Discontinuation
- 1988-07-09 JP JP63171704A patent/JPS6431729A/ja active Pending
- 1988-07-09 KR KR1019880008589A patent/KR890001537A/ko not_active Ceased
- 1988-07-11 PH PH37205A patent/PH27002A/en unknown
- 1988-07-11 BE BE8800802A patent/BE1004835A5/fr not_active IP Right Cessation
- 1988-07-11 IT IT8848172A patent/IT1226632B/it active
- 1988-07-11 AU AU18920/88A patent/AU618008B2/en not_active Ceased
1990
- 1990-01-19 US US07/467,598 patent/US5039680A/en not_active Expired - Fee Related
1991
- 1991-03-05 GB GB9104598A patent/GB2240475B/en not_active Expired - Lifetime
- 1991-10-07 AU AU85628/91A patent/AU633762B2/en not_active Ceased
- 1991-10-07 AU AU85630/91A patent/AU643075B2/en not_active Ceased

Also Published As

Publication number	Publication date
EP0302008A2 (de)	1989-02-01
PT87958B (pt)	1995-03-01
PH27002A (en)	1993-02-01
AU633762B2 (en)	1993-02-04
US5039680A (en)	1991-08-13
JPS6431729A (en)	1989-02-02
DE3822792A1 (de)	1989-01-19
NL8801733A (nl)	1989-02-01
SE8802570L (sv)	1989-03-28
DE3822792C2 (de)	1997-11-27
AU8562891A (en)	1991-12-05
EP0302008A3 (de)	1992-12-23
IT8848172A0 (it)	1988-07-11
IT1226632B (it)	1991-01-28
GB2240475A (en)	1991-08-07
GB2206788B (en)	1992-03-25
FR2617713A1 (fr)	1989-01-13
AU618008B2 (en)	1991-12-12
AU8563091A (en)	1991-12-12
AU643075B2 (en)	1993-11-04
GB9104598D0 (en)	1991-04-17
AT401615B (de)	1996-10-25
AU1892088A (en)	1989-01-12
DK385388D0 (da)	1988-07-08
GB2206788A (en)	1989-01-18
BE1004835A5 (fr)	1993-02-09
SE8802570D0 (sv)	1988-07-08
MY103536A (en)	1993-07-31
HU206042B (en)	1992-08-28
GB2240475B (en)	1992-03-18
FR2617713B1 (de)	1994-08-19
HUT50038A (en)	1989-12-28
GB8816298D0 (en)	1988-08-10
KR890001537A (ko)	1989-03-27
PT87958A (pt)	1989-06-30

Legal Events

Date	Code	Title	Description
1996-03-25	AHB	Application shelved due to non-payment

Publication	Publication Date	Title
DK385388D0 (da)	1988-07-08	Anvendelse af 5ht-3-antagonister
DK208188A (da)	1988-10-17	Anvendelse af 17-ketosteroider
DK263288D0 (da)	1988-05-13	Farmaceutisk praeparat af cefuroxim-axetil
DK363887A (da)	1988-01-15	Anvendelse af bromcruptin
DK193588A (da)	1988-10-11	Anvendelser af dopaminagonister
DK399088A (da)	1989-01-16	Anvendelse af olefine forbindelser
DK530888A (da)	1989-03-25	Leukotrien -ltd4- og - ltb4-antagonister
DK662687A (da)	1988-06-18	Anvendelse af tricycliske carbazoloner
DK185988A (da)	1988-10-16	Anvendelse af antigen
DK587A (da)	1987-01-02	Rensning af zirkonforbindelser
DK475187D0 (da)	1987-09-11	Delta22-derivater af ll-f28249-forbindelser samt anvendelse deraf
DK564886A (da)	1987-05-27	Fungicid anvendelse af tetrahydrobenzothienylurinstofderivater
DK293086A (da)	1986-12-23	Anvendelse af substituerede azabicycloforbindelser
DK102389A (da)	1989-09-05	Anvendelse af interleukin
DK87888A (da)	1988-02-19	Terapeutisk anvendelse af tindijoddeuteroporfyrin
DK104389A (da)	1989-09-05	Anvendelse af imidazolderivater
DK442186A (da)	1986-11-17	Thromboxan antagonister i forbindelse med behandlingen af hormonafhaengig neoplasi
DK316589D0 (da)	1989-06-26	Substituerede azacyclohexylderivater af rifamyciner
DK541487D0 (da)	1987-10-16	Sammenfoejning af materialer
DK237385A (da)	1985-12-01	Anvendelse af dihydroergotamin
DK333587D0 (da)	1987-06-29	Anvendelse af pyridinderivater
DK689388A (da)	1989-06-12	Anvendelse af dihydropyridinderivater
DK118189A (da)	1989-09-12	Anvendelse af piperazinderivat
DK0402857T3 (da)	1991-10-09	Anvendelse af 17beta-cyclopropylamino-androsten-derivater
DK105989A (da)	1990-09-07	Anvendelse af brugt stoeberisand