DK38984A - Pyridazinderivater, som i 3-stillingen er substitueret med amino, og som indvirker paa centralnervesystemet, fremgangsmaade til fremstilling heraf og laegemidler med indhold heraf - Google Patents

Pyridazinderivater, som i 3-stillingen er substitueret med amino, og som indvirker paa centralnervesystemet, fremgangsmaade til fremstilling heraf og laegemidler med indhold heraf Download PDF

Info

Publication number: DK38984A
Authority: DK; Denmark
Prior art keywords: procedures; amino; impact; preparing; nervous system
Prior art date: 1983-01-27

Application number

DK38984A

Other languages

English (en)

Other versions

DK162985B (da

DK162985C (da

DK38984D0 (da

Inventor

Jean-Pierre Chambon

Kathleen Biziere

Camille-Georges Wermuth

Original Assignee

Sanofi Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-01-27

Filing date

1984-01-27

Publication date

1984-07-28

1984-01-27 Application filed by Sanofi Sa filed Critical Sanofi Sa

1984-01-27 Publication of DK38984D0 publication Critical patent/DK38984D0/da

1984-07-28 Publication of DK38984A publication Critical patent/DK38984A/da

1992-01-06 Publication of DK162985B publication Critical patent/DK162985B/da

1992-06-01 Application granted granted Critical

1992-06-01 Publication of DK162985C publication Critical patent/DK162985C/da

Links

-1 AMINO Chemical group 0.000 title 1
210000003169 central nervous system Anatomy 0.000 title 1
239000003814 drug Substances 0.000 title 1
238000000034 method Methods 0.000 title 1
PBMFSQRYOILNGV-UHFFFAOYSA-N pyridazine Chemical group C1=CC=NN=C1 PBMFSQRYOILNGV-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/20—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Neurosurgery (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK038984A 1983-01-27 1984-01-27 Pyridazinderivater, som i 3-stillingen er substitueret med amino, og som indvirker paa centralnervesystemet, fremgangsmaade til fremstilling heraf og laegemidler med indhold heraf DK162985C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR8301234A FR2540113A1 (fr)	1983-01-27	1983-01-27	Acides derives de la pyridazine actifs sur le systeme nerveux central
FR8301234		1983-01-27

Publications (4)

Publication Number	Publication Date
DK38984D0 DK38984D0 (da)	1984-01-27
DK38984A true DK38984A (da)	1984-07-28
DK162985B DK162985B (da)	1992-01-06
DK162985C DK162985C (da)	1992-06-01

Family

ID=9285330

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK038984A DK162985C (da)	1983-01-27	1984-01-27	Pyridazinderivater, som i 3-stillingen er substitueret med amino, og som indvirker paa centralnervesystemet, fremgangsmaade til fremstilling heraf og laegemidler med indhold heraf

Country Status (27)

Country	Link
US (1)	US4721711A (da)
EP (1)	EP0117779B1 (da)
JP (1)	JPS59141564A (da)
KR (1)	KR910000638B1 (da)
AR (1)	AR240045A1 (da)
AT (1)	ATE48417T1 (da)
AU (2)	AU2372984A (da)
CA (1)	CA1238637A (da)
DD (1)	DD220026A5 (da)
DE (1)	DE3480653D1 (da)
DK (1)	DK162985C (da)
ES (1)	ES529081A0 (da)
FI (1)	FI78691C (da)
FR (1)	FR2540113A1 (da)
HU (1)	HU193890B (da)
IE (1)	IE57054B1 (da)
IL (1)	IL70756A (da)
MA (1)	MA20018A1 (da)
NO (1)	NO840313L (da)
NZ (1)	NZ206945A (da)
OA (1)	OA07644A (da)
PH (1)	PH21162A (da)
PL (1)	PL142340B1 (da)
PT (1)	PT77993B (da)
SG (1)	SG93690G (da)
YU (1)	YU14284A (da)
ZA (1)	ZA84502B (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2540113A1 (fr) *	1983-01-27	1984-08-03	Sanofi Sa	Acides derives de la pyridazine actifs sur le systeme nerveux central
DE3664772D1 (en) *	1985-01-14	1989-09-07	Boehringer Ingelheim Kg	12-amino pyridazinoû4',5':3,4¨pyrroloû2,1-a¨isoquinolines, process for their preparation and use
US5082939A (en) *	1987-01-08	1992-01-21	I.S.F. Societa Per Azioni	Pyridazine derivatives
US5106973A (en) *	1987-11-23	1992-04-21	Janssen Pharmaceutica N.V.	Pyridzainamine derivatives
FR2663326B2 (fr) *	1989-11-17	1992-10-16	Sanofi Sa	Derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
US5631255A (en) *	1989-02-07	1997-05-20	Sanofi	Pyridazine derivatives
FR2668151A1 (fr) *	1990-10-23	1992-04-24	Rhone Poulenc Agrochimie	Composes a groupe triazolopyridazine leurs preparations et compositions herbicides les contenant.
FR2676444B1 (fr) *	1991-05-16	1995-03-10	Sanofi Elf	Nouveaux derives d'amino-3 pyridazines actifs sur le systeme nerveux central, procede de preparation et compositions pharmaceutiques en contenant.
CN1038249C (zh) *	1991-08-28	1998-05-06	罗姆和哈斯公司	含有二氢哒嗪酮及其相关化合物的杀菌组合物
US20100210590A1 (en) *	1995-09-27	2010-08-19	Northwestern University	Compositions and treatments for seizure-related disorders
US20030176437A1 (en) *	2001-08-31	2003-09-18	D.M. Watterson	Anti-inflammatory and protein kinase inhibitor compositions and related methods for downregulation of detrimental cellular responses and inhibition of cell death
BRPI0517947A (pt)	2004-11-02	2008-10-21	Univ Northwestern	composto de piridazina, composições e métodos
ATE523199T1 (de) *	2004-11-02	2011-09-15	Univ Northwestern	Pyridazinverbindungen und verfahren
US20100168120A1 (en) *	2006-04-28	2010-07-01	Neuromedix Inc.	Salts of pyridazine compounds
CA2650711A1 (en) *	2006-04-28	2007-11-08	Northwestern University	Compositions and treatments using pyridazine compounds and cholinesterase inhibitors
JP2009535344A (ja)	2006-04-28	2009-10-01	ノースウェスタンユニバーシティ	神経炎症性疾患の処置のためのピリダジン化合物を含む処方物
EP2142498A2 (en) *	2007-04-02	2010-01-13	Institute for Oneworld Health	Cftr inhibitor compounds and uses thereof
EP2278879B1 (en)	2008-04-21	2016-06-15	PATH Drug Solutions	Compounds, compositions and methods comprising oxadiazole derivatives
WO2009131958A2 (en) *	2008-04-21	2009-10-29	Institute For Oneworld Health	Compounds, compositions and methods comprising triazine derivatives
US20090270398A1 (en) *	2008-04-21	2009-10-29	Institute For Oneworld Health	Compounds, Compositions and Methods Comprising Pyridazine Derivatives
US8236838B2 (en) *	2008-04-21	2012-08-07	Institute For Oneworld Health	Compounds, compositions and methods comprising isoxazole derivatives
JP2012503005A (ja) *	2008-09-19	2012-02-02	インスティテュートフォアワンワールドヘルス	イミダゾール誘導体およびトリアゾール誘導体を含む、化合物、組成物ならびに方法。
US8343976B2 (en) *	2009-04-20	2013-01-01	Institute For Oneworld Health	Compounds, compositions and methods comprising pyrazole derivatives
US20100267706A1 (en) *	2009-04-20	2010-10-21	Institute For Oneworld Health	Compounds, Compositions and Methods Comprising Pyridazine Derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2510998B1 (fr) *	1981-08-07	1986-01-10	Sanofi Sa	Nouveaux derives amines de la pyridazine, leur procede de preparation et les medicaments, a action desinhibitrice, qui en comportent
FR2510997A1 (fr) *	1981-08-10	1983-02-11	Sanofi Sa	Nouveaux derives de la methyl-4 phenyl-6 pyridazine, procede pour leur preparation et medicaments actifs sur le systeme nerveux central en contenant
FR2540113A1 (fr) *	1983-01-27	1984-08-03	Sanofi Sa	Acides derives de la pyridazine actifs sur le systeme nerveux central
US4565814A (en) *	1983-01-28	1986-01-21	Sanofi	Pyridazine derivatives having a psychotropic action and compositions

1983
- 1983-01-27 FR FR8301234A patent/FR2540113A1/fr active Granted
1984
- 1984-01-18 CA CA000445481A patent/CA1238637A/en not_active Expired
- 1984-01-20 PH PH30135A patent/PH21162A/en unknown
- 1984-01-20 AR AR295532A patent/AR240045A1/es active
- 1984-01-23 PT PT77993A patent/PT77993B/pt not_active IP Right Cessation
- 1984-01-23 ES ES529081A patent/ES529081A0/es active Granted
- 1984-01-23 IL IL70756A patent/IL70756A/xx unknown
- 1984-01-23 ZA ZA84502A patent/ZA84502B/xx unknown
- 1984-01-23 IE IE149/84A patent/IE57054B1/en not_active IP Right Cessation
- 1984-01-24 AU AU23729/84A patent/AU2372984A/en not_active Abandoned
- 1984-01-25 EP EP84400156A patent/EP0117779B1/fr not_active Expired
- 1984-01-25 DE DE8484400156T patent/DE3480653D1/de not_active Expired - Fee Related
- 1984-01-25 AT AT84400156T patent/ATE48417T1/de not_active IP Right Cessation
- 1984-01-26 FI FI840323A patent/FI78691C/fi not_active IP Right Cessation
- 1984-01-26 KR KR1019840000335A patent/KR910000638B1/ko not_active Expired
- 1984-01-26 OA OA58216A patent/OA07644A/xx unknown
- 1984-01-26 HU HU84331A patent/HU193890B/hu not_active IP Right Cessation
- 1984-01-26 NZ NZ206945A patent/NZ206945A/en unknown
- 1984-01-26 NO NO840313A patent/NO840313L/no unknown
- 1984-01-26 MA MA20239A patent/MA20018A1/fr unknown
- 1984-01-26 DD DD84259650A patent/DD220026A5/de not_active IP Right Cessation
- 1984-01-27 JP JP59013234A patent/JPS59141564A/ja active Pending
- 1984-01-27 YU YU00142/84A patent/YU14284A/xx unknown
- 1984-01-27 PL PL1984245931A patent/PL142340B1/pl unknown
- 1984-01-27 DK DK038984A patent/DK162985C/da active
1985
- 1985-10-03 US US06/783,686 patent/US4721711A/en not_active Expired - Fee Related
1988
- 1988-08-18 AU AU21421/88A patent/AU652118B2/en not_active Ceased
1990
- 1990-11-19 SG SG936/90A patent/SG93690G/en unknown

Also Published As

Publication number	Publication date
PL245931A1 (en)	1985-07-16
PT77993A (fr)	1984-02-01
ATE48417T1 (de)	1989-12-15
YU14284A (en)	1986-12-31
PH21162A (en)	1987-08-05
MA20018A1 (fr)	1984-10-01
EP0117779B1 (fr)	1989-12-06
PT77993B (fr)	1986-04-10
FR2540113A1 (fr)	1984-08-03
DE3480653D1 (de)	1990-01-11
FI840323L (fi)	1984-07-28
FI78691C (fi)	1989-09-11
JPS59141564A (ja)	1984-08-14
SG93690G (en)	1991-01-18
FR2540113B1 (da)	1985-05-17
ZA84502B (en)	1984-09-26
ES8500243A1 (es)	1984-10-01
HU193890B (en)	1987-12-28
DK162985B (da)	1992-01-06
NZ206945A (en)	1987-07-31
OA07644A (fr)	1985-05-23
NO840313L (no)	1984-07-30
FI840323A0 (fi)	1984-01-26
ES529081A0 (es)	1984-10-01
AR240045A1 (es)	1990-01-31
IE840149L (en)	1984-07-27
KR910000638B1 (ko)	1991-01-31
CA1238637A (en)	1988-06-28
AU2142188A (en)	1989-03-16
DK162985C (da)	1992-06-01
IL70756A0 (en)	1984-04-30
AU2372984A (en)	1984-08-02
DD220026A5 (de)	1985-03-20
KR840007586A (ko)	1984-12-08
EP0117779A1 (fr)	1984-09-05
IL70756A (en)	1987-03-31
FI78691B (fi)	1989-05-31
AU652118B2 (en)	1994-08-18
US4721711A (en)	1988-01-26
IE57054B1 (en)	1992-04-08
DK38984D0 (da)	1984-01-27
PL142340B1 (en)	1987-10-31

Publication	Publication Date	Title
DK38984D0 (da)	1984-01-27	Pyridazinderivater, som i 3-stillingen er substitueret med amino, og som indvirker pa centralnervesystemet, fremgangsmade til fremstilling heraf og laegemidler med indhold heraf
DK286786A (da)	1987-02-16	Hydrogeldannende polymersammensaetning, fremgangsmaade til fremstilling af samme samt absorberende struktur og artikel indeholdendesammensaetningen
DK163988C (da)	1992-09-21	9alfa,11alfa-epoxy-20-spiroxaner og analoge deraf med aaben tetrahydrofuranring e samt deres fremstilling og farmaceutiske praeparater indeholdende dem
DK181983D0 (da)	1983-04-25	1,8-naphthyridin- og 1,5,8-azanaphthyridin-derivater, fremgangsmade til deres fremstilling samt deres anvendelse
EP0261977A3 (en)	1989-04-05	Catechol derivatives, and preventive and remedial preparations for regressive disorders in the central nervous system
FI922235A7 (fi)	1992-11-17	Menetelmä keskushermostojärjestelmään vaikuttavien 3-aminopyridatsiinijohdannaisten valmistamiseksi
DK210483D0 (da)	1983-05-11	Pyrogallolderivater, deres anvendelse og fremgangsmade til fremstilling deraf
NO863765D0 (no)	1986-09-22	Arylmetylazoler og salter derav samt fremgangsmaater til fremstilling derav.
NO862976L (no)	1987-01-26	Oksalkylerte polyesteraminer, fremgangsmaate til deres fremstilling, og deres anvendelse.
NO822796L (no)	1983-03-04	Aminoorganoaminosilaner, fremgangsmaate til deres fremstilling og deres anvendelse
DK170788D0 (da)	1988-03-28	Dihydropyridazinonderivater, fremgangsmaader til fremstilling heraf samt laegemidler indeholdende disse
DK361288D0 (da)	1988-06-30	Hydroxyethylazolylderivater, deres fremstilling og anvendelse samt mellemprodukter til fremstilling og disses fremstilling
DK581183A (da)	1984-06-18	2-azabicyclo(2.2.1)heptan-derivater, fremgangsmaader til deres fremstilling, midler indeholdende disse derivater og deres anvendelse, samt 2-azabicyclo(2.2.1)heptan-derivater som mellemprodukter samt fremgangsmaader til deres fremstilling
DK136784D0 (da)	1984-02-29	Pyrazolo(1,5-a)pyridinderivater samt fremgangsmaade til fremstilling deraf
DE3677256D1 (de)	1991-03-07	Polarisationsselektiver reflektor und verfahren zu dessen herstellung.
NO905030D0 (no)	1990-11-20	Ekstrudert poroes struktur, samt fremgangsmaate og apparat for fremstilling av strukturen.
DK136684A (da)	1984-09-15	Pyrazolo(1,5-a)pyridinderivater samt fremgangsmaade til fremstilling deraf
DK247884D0 (da)	1984-05-17	Substituerede tetrahydrothiopyran-3,5-dion-4-carboxamider,fremgangsmaade til deres fremstilling og deres anvendelse samt mellemprodukter til fremstillingen
DK12084A (da)	1984-07-13	Substituerede carboxy-thiazolo(3,2-a)pyrimidinderivater samt fremgangsmaade til fremstilling heraf
NO881554D0 (no)	1988-04-11	Fremgangsmaate for fremstilling av 1-((1,1-difenyl)-1-alkenyl)- piperazin med virkning paa sentralnervesystemet.
DK393282A (da)	1983-03-04	Anilino-1,2,3-triazol-derivater, fremgangsmaade til deres fremstilling samt deres anvendelse
NO923592L (no)	1992-08-17	Polyhydroksycyklopentanderivat og fremgangsmaate til fremstilling derav, samt mikroorganisme som er anvendelig i fremgangsmaaten
ES272802Y (es)	1984-05-01	Soporte expositor para relojes, perfeccionado.
ES1004494Y (es)	1992-11-16	Gafa perfeccionada para canalones y similares.
NO913297L (no)	1991-08-22	Nye beta-karboliner, fremgangsmaate for deres fremstilling og anvendelse derav i legemidler.