DK3953348T3 - Forbindelser, sammensætninger og fremgangsmåder - Google Patents

Forbindelser, sammensætninger og fremgangsmåder Download PDF

Info

Publication number
DK3953348T3
DK3953348T3 DK20787582.4T DK20787582T DK3953348T3 DK 3953348 T3 DK3953348 T3 DK 3953348T3 DK 20787582 T DK20787582 T DK 20787582T DK 3953348 T3 DK3953348 T3 DK 3953348T3
Authority
DK
Denmark
Prior art keywords
compositions
compounds
methods
Prior art date
Application number
DK20787582.4T
Other languages
English (en)
Inventor
Vicente Fidalgo Javier De
Anthony A Estrada
Jianwen A Feng
Zachary K Sweeney
Original Assignee
Denali Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Denali Therapeutics Inc filed Critical Denali Therapeutics Inc
Application granted granted Critical
Publication of DK3953348T3 publication Critical patent/DK3953348T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK20787582.4T 2019-04-11 2020-04-10 Forbindelser, sammensætninger og fremgangsmåder DK3953348T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962832775P 2019-04-11 2019-04-11
PCT/US2020/027742 WO2020210684A1 (en) 2019-04-11 2020-04-10 Compounds, compositions and methods

Publications (1)

Publication Number Publication Date
DK3953348T3 true DK3953348T3 (da) 2025-03-17

Family

ID=72752101

Family Applications (1)

Application Number Title Priority Date Filing Date
DK20787582.4T DK3953348T3 (da) 2019-04-11 2020-04-10 Forbindelser, sammensætninger og fremgangsmåder

Country Status (19)

Country Link
US (1) US12358896B2 (da)
EP (1) EP3953348B1 (da)
JP (1) JP7623294B2 (da)
KR (1) KR102962366B1 (da)
CN (1) CN113939294A (da)
AR (1) AR118641A1 (da)
AU (1) AU2020272045B2 (da)
BR (1) BR112021020027A2 (da)
CA (1) CA3136447A1 (da)
DK (1) DK3953348T3 (da)
EA (1) EA202192530A1 (da)
ES (1) ES3018383T3 (da)
IL (1) IL287120B2 (da)
MA (1) MA55624A (da)
MX (1) MX2021012392A (da)
SG (1) SG11202111058XA (da)
TW (1) TWI851710B (da)
WO (1) WO2020210684A1 (da)
ZA (1) ZA202107499B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3086182A1 (en) 2017-12-20 2019-06-27 Denali Therapeutics Inc. Process for the preparation of pyrimidinyl-4-aminopyrazole compounds
AU2021371697B2 (en) * 2020-10-29 2024-10-24 Suzhou Yabao Pharmaceutical R&D Co., Ltd. Substituted diarylamine compound, pharmaceutical composition thereof, preparation method therefor, and use thereof
CN116120291B (zh) * 2023-04-11 2023-06-30 英矽智能科技(上海)有限公司 吲唑类化合物及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101566091B1 (ko) 2010-11-10 2015-11-04 에프. 호프만-라 로슈 아게 Lrrk2 조절제로서 피라졸 아미노피리미딘 유도체
PT3472153T (pt) * 2016-06-16 2021-12-31 Denali Therapeutics Inc Pirimidin-2-ilamino-1h-pirazóis como inibidores de lrrk2 para uso no tratamento de distúrbios neurodegenerativos
WO2018217946A1 (en) * 2017-05-24 2018-11-29 Denali Therapeutics Inc. Compounds, compositions and methods
CA3086182A1 (en) 2017-12-20 2019-06-27 Denali Therapeutics Inc. Process for the preparation of pyrimidinyl-4-aminopyrazole compounds

Also Published As

Publication number Publication date
ES3018383T3 (es) 2025-05-16
EP3953348B1 (en) 2024-12-18
CN113939294A (zh) 2022-01-14
AU2020272045A1 (en) 2021-10-28
IL287120B1 (en) 2025-02-01
BR112021020027A2 (pt) 2021-12-07
TWI851710B (zh) 2024-08-11
JP7623294B2 (ja) 2025-01-28
WO2020210684A1 (en) 2020-10-15
JP2022526015A (ja) 2022-05-20
AR118641A1 (es) 2021-10-20
KR102962366B1 (ko) 2026-05-11
TW202104213A (zh) 2021-02-01
AU2020272045B2 (en) 2026-01-15
EP3953348A1 (en) 2022-02-16
MX2021012392A (es) 2021-11-12
CA3136447A1 (en) 2020-10-15
EA202192530A1 (ru) 2022-03-15
IL287120B2 (en) 2025-06-01
US20220220094A1 (en) 2022-07-14
EP3953348A4 (en) 2023-01-18
SG11202111058XA (en) 2021-11-29
ZA202107499B (en) 2022-06-29
IL287120A (en) 2021-12-01
KR20210151887A (ko) 2021-12-14
US12358896B2 (en) 2025-07-15
MA55624A (fr) 2022-02-16

Similar Documents

Publication Publication Date Title
DK3676297T3 (da) Forbindelser, sammensætninger og fremgangsmåder
IL285302A (en) Compounds, preparations and methods
EP3917927A4 (en) IMMUNE MODULATORS, COMPOSITIONS AND METHODS THEREOF
DK3580561T3 (da) Hla-baserede metoder, sammensætninger og anvendelse heraf
DK4122997T3 (da) Stabiliserede fluorolefinsammensætninger og fremgangsmåder til fremstilling, oplagring og anvendelse deraf
LT4084779T (lt) 1-(4-brom-5-(1-etil-7-(metilamino)-2-okso-1,2-dihidro-1,6-naftiridin-3-il) -2- fluorfenil)-3-fenilkarbamido kompozicijos
DK3407888T3 (da) Pyridopyrroloquinoxalinforbindelser, deres sammensætninger og anvendelser
DK3924443T3 (da) Compositions
DK4428234T3 (da) Direkte-til-bibliotek-fremgangsmåder, systemer og sammensætninger
EP3930851A4 (en) COMBINATION THERAPIES
EP3919491C0 (en) AKT INHIBITOR
EP3967726A4 (en) Curable composition
EP3742771C0 (en) M2M SM-SR TO SM-DP NOTIFICATION
EP3871694A4 (en) COMPOSITION
DK3833682T3 (da) Selvmordsmolekyle sammensætninger og fremgangsmåder
DK4034535T3 (da) Aza-quinolinforbindelser og anvendelser deraf
EP3896109A4 (en) CURABLE COMPOSITION
DK3592430T3 (da) Antimikrobielle forbindelser, sammensætninger og anvendelser heraf
DK3892621T3 (da) Haloallylaminforbindelser og anvendelse deraf
EP3981256A4 (en) COMPOSITION
EP3954721A4 (en) Composition
EP3941942A4 (en) COMPOSITION
EP3912517C0 (en) FRAME
EP3929260A4 (en) CURABLE COMPOSITION
DK3932909T3 (da) Benzoindazolonforbindelse og mellemprodukt heraf