DK3993777T3 - Komprimerede macitentansammensætninger, fremgangsmåder og anvendelser deraf - Google Patents

Komprimerede macitentansammensætninger, fremgangsmåder og anvendelser deraf Download PDF

Info

Publication number
DK3993777T3
DK3993777T3 DK20750358.2T DK20750358T DK3993777T3 DK 3993777 T3 DK3993777 T3 DK 3993777T3 DK 20750358 T DK20750358 T DK 20750358T DK 3993777 T3 DK3993777 T3 DK 3993777T3
Authority
DK
Denmark
Prior art keywords
macitent
compressed
compositions
processes
macitent compositions
Prior art date
Application number
DK20750358.2T
Other languages
English (en)
Inventor
Serra João Pedro Silva
Pereira Ricardo José Camilo Ferreira
Original Assignee
Tecnimede Sociedade Tecnico Medicinal Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=71899791&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3993777(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Tecnimede Sociedade Tecnico Medicinal Sa filed Critical Tecnimede Sociedade Tecnico Medicinal Sa
Application granted granted Critical
Publication of DK3993777T3 publication Critical patent/DK3993777T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK20750358.2T 2019-07-05 2020-07-03 Komprimerede macitentansammensætninger, fremgangsmåder og anvendelser deraf DK3993777T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PT11563219 2019-07-05
EP19185065 2019-07-08
PCT/IB2020/056304 WO2021005478A1 (en) 2019-07-05 2020-07-03 Compressed macitentan compositions, methods and uses thereof

Publications (1)

Publication Number Publication Date
DK3993777T3 true DK3993777T3 (da) 2024-09-16

Family

ID=71899791

Family Applications (1)

Application Number Title Priority Date Filing Date
DK20750358.2T DK3993777T3 (da) 2019-07-05 2020-07-03 Komprimerede macitentansammensætninger, fremgangsmåder og anvendelser deraf

Country Status (14)

Country Link
US (1) US20220249381A1 (da)
EP (2) EP4417254A3 (da)
CN (1) CN114096239B (da)
AU (1) AU2020309223B2 (da)
BR (1) BR112022000117A2 (da)
CA (1) CA3144613A1 (da)
CL (1) CL2022000008A1 (da)
CO (1) CO2021017646A2 (da)
DK (1) DK3993777T3 (da)
FI (1) FI3993777T3 (da)
HU (1) HUE068040T2 (da)
MX (1) MX2022000267A (da)
PE (1) PE20220593A1 (da)
WO (1) WO2021005478A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022258796A1 (en) * 2021-06-11 2022-12-15 Actelion Pharmaceuticals Ltd Dispersible tablet for oral administration
EP4154873A1 (en) * 2021-09-22 2023-03-29 Sanovel Ilac Sanayi Ve Ticaret A.S. The tablet comprising macitentan
EP4456983A4 (en) * 2021-12-30 2025-09-17 Humanis Saglik Anonim Sirketi PHARMACEUTICAL COMPOSITIONS COMPRISING MACITENTAN AS ACTIVE INGREDIENT AND OTHER RELEVANT EXCIPIENTS

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1345920B1 (en) 2000-12-18 2006-04-12 Actelion Pharmaceuticals Ltd. Novel sulfamides and their use as endothelin receptor antagonists
JP4955685B2 (ja) 2005-09-12 2012-06-20 アクテリオン ファーマシューティカルズ リミテッド ピリミジン−スルファミドを含む安定な医薬組成物
WO2010054845A1 (en) 2008-11-17 2010-05-20 Nycomed Pharma As Improved dissolution stability of calcium carbonate tablets
DE14721256T1 (de) * 2013-04-22 2017-03-16 Sandoz Ag Pharmazeutische zusammensetzungen mit kristallinem macitentan
CN104411691B (zh) * 2013-06-14 2016-05-25 杭州普晒医药科技有限公司 马西替坦晶体及其制备方法、其药物组合物和用途
IN201641002749A (da) 2016-01-25 2017-09-15 Hetero Research Foundation
CN107913256A (zh) * 2016-10-08 2018-04-17 郑州泰丰制药有限公司 一种治疗肺动脉高压的马西替坦口腔崩解片及其制备方法
WO2018153925A1 (en) * 2017-02-22 2018-08-30 Amneal Pharmaceuticals Company Gmbh Stable pharmaceutical compositions comprising macitentan
CN109260163A (zh) * 2018-10-07 2019-01-25 威海云睿信息科技有限公司 一种马西替坦片剂组合物

Also Published As

Publication number Publication date
CL2022000008A1 (es) 2022-10-07
BR112022000117A2 (pt) 2022-02-15
FI3993777T3 (fi) 2024-09-10
PE20220593A1 (es) 2022-04-22
WO2021005478A1 (en) 2021-01-14
US20220249381A1 (en) 2022-08-11
CA3144613A1 (en) 2021-01-14
EP3993777A1 (en) 2022-05-11
AU2020309223B2 (en) 2025-05-29
EP4417254A3 (en) 2025-03-05
CO2021017646A2 (es) 2022-01-17
CN114096239A (zh) 2022-02-25
EP4417254A2 (en) 2024-08-21
MX2022000267A (es) 2022-02-03
AU2020309223A1 (en) 2022-03-03
EP3993777B1 (en) 2024-06-12
HUE068040T2 (hu) 2024-12-28
CN114096239B (zh) 2024-04-12

Similar Documents

Publication Publication Date Title
DK3580561T3 (da) Hla-baserede metoder, sammensætninger og anvendelse heraf
DK3676297T3 (da) Forbindelser, sammensætninger og fremgangsmåder
DK3712150T3 (da) Makrocyklisk forbindelse, der tjener som wee1-hæmmer, og anvendelser deraf
DK3478811T3 (da) Rengøringssammensætninger og anvendelser deraf
DK4428234T3 (da) Direkte-til-bibliotek-fremgangsmåder, systemer og sammensætninger
DK3640207T3 (da) Molekularsi scm-15, syntesefremgangsmåde dertil og anvendelse deraf
DK3612579T3 (da) Pultrudat, fremstilling og anvendelse heraf
GB202017595D0 (en) Compositions, and methods and uses relating thereto
GB201901099D0 (en) Methods, uses and compositions
EP4058568A4 (en) PLANT VECTORS, COMPOSITIONS AND RELATED USES
GB2576614B (en) Compositions, uses and methods
DK3592430T3 (da) Antimikrobielle forbindelser, sammensætninger og anvendelser heraf
EP3940230A4 (en) Compressor
DK3993777T3 (da) Komprimerede macitentansammensætninger, fremgangsmåder og anvendelser deraf
EP4053412A4 (en) Compressor
DK3932909T3 (da) Benzoindazolonforbindelse og mellemprodukt heraf
IL291645A (en) Packed tower
DK3712162T3 (da) Smac-mimetica anvendt som iap-inhibitorer og anvendelse deraf
DK3953348T3 (da) Forbindelser, sammensætninger og fremgangsmåder
GB201804163D0 (en) Uses, compositions and methods
DK3983387T3 (da) Sulfonylurinstofderivater og anvendelser deraf
EP3933198C0 (en) COMPRESSOR
ZA202104192B (en) Mmpl3 inhibitors, compositions and uses thereof
IL280078A (en) Thrombin inhibitors, preparations and their uses
EP4077273C0 (fr) Aldimines et leurs utilisations