DK400884A - Tautomere trans-(+-)-alkylerede octahydropyrazolo(3,4-g)- og -(4,3-f)-quinoliner, fremgangsmaade til fremstilling heraf og mellemprodukt til brug ved fremgangsmaaden - Google Patents

Tautomere trans-(+-)-alkylerede octahydropyrazolo(3,4-g)- og -(4,3-f)-quinoliner, fremgangsmaade til fremstilling heraf og mellemprodukt til brug ved fremgangsmaaden Download PDF

Info

Publication number: DK400884A
Authority: DK; Denmark
Prior art keywords: octahydropyrazolo; quinolines; tautomer; alkylated; intermediates
Prior art date: 1983-09-26

Application number

DK400884A

Other languages

Danish (da)

English (en)

Other versions

DK400884D0 (da

Inventor

John Mehnert Schaus

Diane Lynn Huser

Richard Nolan Booher

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-09-26

Filing date

1984-08-22

Publication date

1985-03-27

1984-08-22 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1984-08-22 Publication of DK400884D0 publication Critical patent/DK400884D0/da

1985-03-27 Publication of DK400884A publication Critical patent/DK400884A/da

Links

229940111121 antirheumatic drug quinolines Drugs 0.000 title 1
239000000543 intermediate Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/10—Spiro-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

DK400884A 1983-09-26 1984-08-22 Tautomere trans-(+-)-alkylerede octahydropyrazolo(3,4-g)- og -(4,3-f)-quinoliner, fremgangsmaade til fremstilling heraf og mellemprodukt til brug ved fremgangsmaaden DK400884A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US53551983A	1983-09-26	1983-09-26

Publications (2)

Publication Number	Publication Date
DK400884D0 DK400884D0 (da)	1984-08-22
DK400884A true DK400884A (da)	1985-03-27

Family

ID=24134591

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK400884A DK400884A (da)	1983-09-26	1984-08-22	Tautomere trans-(+-)-alkylerede octahydropyrazolo(3,4-g)- og -(4,3-f)-quinoliner, fremgangsmaade til fremstilling heraf og mellemprodukt til brug ved fremgangsmaaden

Country Status (10)

Country	Link
EP (1)	EP0145121B1 (mo)
JP (4)	JPS6110583A (mo)
KR (1)	KR870001159B1 (mo)
CA (1)	CA1270488A (mo)
DE (1)	DE3484925D1 (mo)
DK (1)	DK400884A (mo)
GB (1)	GB2146984B (mo)
GR (1)	GR80200B (mo)
HU (1)	HU199836B (mo)
IL (1)	IL72729A (mo)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6392722A (ja) *	1986-10-03	1988-04-23	Unitika Ltd	熱接着繊維およびその不織布
JPS6392723A (ja) *	1986-10-06	1988-04-23	Unitika Ltd	湿潤性複合繊維およびその不織布
JPS6420322A (en) *	1987-07-13	1989-01-24	Mitsubishi Petrochemical Co	Conjugated fiber
JPH01204617A (ja) *	1988-02-09	1989-08-17	Chisso Corp	敷物
GB8828669D0 (en) *	1988-12-08	1989-01-11	Lilly Industries Ltd	Organic compounds
KR20000008130A (ko) *	1998-07-10	2000-02-07	조정래	폴리에스터계 탄성사용 공중합물의 제조방법
US8829024B2 (en)	2011-01-07	2014-09-09	Corcept Therapeutics, Inc.	Combination steroid and glucocorticoid receptor antagonist therapy
US20130225633A1 (en) *	2012-02-27	2013-08-29	Corcept Therapeutics, Inc.	Phenyl heterocycloalkyl glucocorticoid receptor modulators
US12226412B2 (en)	2012-05-25	2025-02-18	Corcept Therapeutics, Inc.	Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators
US8859774B2 (en)	2012-05-25	2014-10-14	Corcept Therapeutics, Inc.	Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators
PL3848027T3 (pl)	2013-11-25	2023-07-24	Corcept Therapeutics Incorporated	Skondensowane oktahydrozwiązki azadekaliny jako modulatory receptora glukokortykoidowego
MX2019011543A (es)	2017-03-31	2019-12-16	Corcept Therapeutics Inc	Moduladores del receptor de glucocorticoides para el tratamiento de cancer cervical.
US11389432B2 (en)	2018-12-19	2022-07-19	Corcept Therapeutics Incorporated	Methods of treating cancer comprising administration of a glucocorticoid receptor modulator and a cancer chemotherapy agent
US11464764B2 (en)	2018-12-19	2022-10-11	Corcept Therapeutics Incorporated	Pharmaceutical formulations containing relacorilant, a heteroaryl-ketone fused azadecalin compound
US11234971B2 (en)	2018-12-19	2022-02-01	Corcept Therapeutics Incorporated	Methods of treating cancer comprising administration of a glucocorticoid receptor modulator and a cancer chemotherapy agent
JP7789561B2 (ja)	2019-02-22	2025-12-22	コーセプトセラピューティクス，インコーポレイテッド	レラコリラント、ヘテロアリール－ケトン縮合アザデカリングルココルチコイド受容体調節物質の治療用途
JP7569492B2 (ja)	2019-12-11	2024-10-18	コーセプトセラピューティクス，インコーポレイテッド	抗精神病薬誘発性体重増加のミリコリラントによる治療方法
WO2021242912A1 (en)	2020-05-27	2021-12-02	Corcept Therapeutics Incorporated	Concomitant administration of glucocorticoid receptor modulator relacorilant and paclitaxel, a dual substrate of cyp2c8 and cyp3a4
WO2022134033A1 (en)	2020-12-25	2022-06-30	Corcept Therapeutics Incorporated	Methods of preparing heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators
US12433882B2 (en)	2022-10-28	2025-10-07	Corcept Therapeutics Incorporated	Treatments for amyotrophic lateral sclerosis using dazucorilant

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4198415A (en) *	1979-01-22	1980-04-15	Eli Lilly And Company	Prolactin inhibiting octahydro pyrazolo[3,4-g]quinolines
US4230861A (en) *	1979-01-22	1980-10-28	Eli Lilly And Company	1-And/or 7-substituted-6-hydroxy (or oxo)-3-decahydroquinoline carboxylic acids
SU776048A1 (ru) *	1979-06-05	1983-09-23	Институт Бисорганической Химии Ан Бсср	Производные 8-аза-16-оксагона-17-онов, про вл ющие противовоспалительную,мембраностабилизирующую и антифибринолитическую активность,и способ их получени
US4252945A (en) *	1979-07-11	1981-02-24	E. R. Squibb & Sons, Inc.	Process for preparing pyrazolo[1,5-c]-quinazoline derivatives and novel intermediates
US4367231A (en) *	1979-09-14	1983-01-04	Eli Lilly And Company	Method of using octahydro pyrazolo[3,4-g]quinolines
ES524452A0 (es) *	1982-11-03	1985-04-16	Lilly Co Eli	Un procedimiento para la preparacion de derivados de pirazolo-quinolinas.

1984
- 1984-08-20 CA CA000461330A patent/CA1270488A/en not_active Expired - Lifetime
- 1984-08-20 IL IL72729A patent/IL72729A/xx unknown
- 1984-08-21 GB GB08421159A patent/GB2146984B/en not_active Expired
- 1984-08-21 DE DE8484305685T patent/DE3484925D1/de not_active Expired - Lifetime
- 1984-08-21 EP EP84305685A patent/EP0145121B1/en not_active Expired - Lifetime
- 1984-08-22 HU HU843161A patent/HU199836B/hu not_active IP Right Cessation
- 1984-08-22 DK DK400884A patent/DK400884A/da not_active Application Discontinuation
- 1984-08-23 GR GR80200A patent/GR80200B/el unknown
- 1984-08-24 JP JP59177382A patent/JPS6110583A/ja active Granted
- 1984-08-24 KR KR1019840005148A patent/KR870001159B1/ko not_active Expired
1992
- 1992-09-16 JP JP4246412A patent/JPH05194511A/ja active Pending
- 1992-09-16 JP JP4246440A patent/JPH0660183B2/ja not_active Expired - Lifetime
- 1992-09-16 JP JP4246442A patent/JPH0625251A/ja active Pending

Also Published As

Publication number	Publication date
JPH0660183B2 (ja)	1994-08-10
DE3484925D1 (de)	1991-09-19
GB8421159D0 (en)	1984-09-26
EP0145121B1 (en)	1991-08-14
JPH05194527A (ja)	1993-08-03
HU199836B (en)	1990-03-28
JPH05194511A (ja)	1993-08-03
IL72729A (en)	1988-02-29
KR870001159B1 (ko)	1987-06-13
EP0145121A2 (en)	1985-06-19
GB2146984A (en)	1985-05-01
CA1270488A (en)	1990-06-19
JPH0625251A (ja)	1994-02-01
EP0145121A3 (en)	1988-04-27
JPS6110583A (ja)	1986-01-18
GR80200B (en)	1985-01-02
HUT34750A (en)	1985-04-28
IL72729A0 (en)	1984-11-30
KR850002480A (ko)	1985-05-13
DK400884D0 (da)	1984-08-22
GB2146984B (en)	1987-04-08
JPH0568475B2 (mo)	1993-09-29

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Legal Events

Date	Code	Title	Description
1993-08-16	ATS	Application withdrawn