DK413180A - Fremgangsmaade til fremstilling af n-(5-tetrazolyl)-1-oxo-1h-thiazolo (3,2-a)pyrimidin-2-carboxamider eller farmaceutisk acceptable kationsalte deraf samt mellemprodukter ved fremgangsmaaden - Google Patents

Fremgangsmaade til fremstilling af n-(5-tetrazolyl)-1-oxo-1h-thiazolo (3,2-a)pyrimidin-2-carboxamider eller farmaceutisk acceptable kationsalte deraf samt mellemprodukter ved fremgangsmaaden

Info

Publication number: DK413180A
Authority: DK; Denmark
Prior art keywords: thiazolo; tetrazolyl; oxo; procedure; preparation
Prior art date: 1979-11-23

Application number

DK413180A

Other languages

English (en)

Other versions

DK151811B (da

DK151811C (da

Inventor

S B Kadin

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-11-23

Filing date

1980-09-30

Publication date

1981-05-24

1980-09-30 Application filed by Pfizer filed Critical Pfizer

1981-05-24 Publication of DK413180A publication Critical patent/DK413180A/da

1984-01-12 Priority to DK0131/84A priority Critical patent/DK13184D0/da

1988-01-04 Publication of DK151811B publication Critical patent/DK151811B/da

1988-06-06 Application granted granted Critical

1988-06-06 Publication of DK151811C publication Critical patent/DK151811C/da

Links

-1 5-TETRAZOLYL Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Immunology (AREA)
Diabetes (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Thiazole And Isothizaole Compounds (AREA)

DK413180A 1979-11-23 1980-09-30 Analogifremgangsmaade til fremstilling af n-(5-tetrazolyl)-1-oxo-1h-thiazolooe3,2-aaa-pyrimidin-2-carboxamider eller farmaceutisk acceptable kationsalte deraf samt 1-oxo-1h-thiazolooe3,2-aaapyrimidin-2-carboxylsyrer til anvendelse som udgangsmaterialer ved fremgangsmaaden DK151811C (da)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
DK0131/84A DK13184D0 (da)	1979-11-23	1984-01-12	Analogifremgangsmade til fremstilling af 1-oxo-1h-thiazolo(3,2-a)pyrimidin-2-carboxylsyrer eller farmaceutisk acceptable kationsalte deraf samt 1-oxo-1h-thiazolo(3,2-a)pyrimidin-2-carboxylsyreestere til anvendelse som mellemprodukter ved fremgangsmaden

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US9663179A	1979-11-23	1979-11-23
US9663179		1979-11-23

Publications (3)

Publication Number	Publication Date
DK413180A true DK413180A (da)	1981-05-24
DK151811B DK151811B (da)	1988-01-04
DK151811C DK151811C (da)	1988-06-06

Family

ID=22258306

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK413180A DK151811C (da)	1979-11-23	1980-09-30	Analogifremgangsmaade til fremstilling af n-(5-tetrazolyl)-1-oxo-1h-thiazolooe3,2-aaa-pyrimidin-2-carboxamider eller farmaceutisk acceptable kationsalte deraf samt 1-oxo-1h-thiazolooe3,2-aaapyrimidin-2-carboxylsyrer til anvendelse som udgangsmaterialer ved fremgangsmaaden

Country Status (35)

Country	Link
JP (1)	JPS5687586A (da)
KR (1)	KR830004322A (da)
AR (2)	AR228859A1 (da)
AT (1)	AT380883B (da)
AU (1)	AU520995B2 (da)
BE (1)	BE886319A (da)
CA (1)	CA1143731A (da)
CH (1)	CH649299A5 (da)
CS (1)	CS241476B2 (da)
DD (1)	DD154608A5 (da)
DE (2)	DE3043979C2 (da)
DK (1)	DK151811C (da)
EG (1)	EG14929A (da)
ES (1)	ES8203363A1 (da)
FI (1)	FI67706C (da)
FR (1)	FR2470132A1 (da)
GB (1)	GB2063862B (da)
GR (1)	GR72132B (da)
GT (1)	GT198066458A (da)
HU (1)	HU179091B (da)
IE (1)	IE50404B1 (da)
IL (1)	IL61535A (da)
IN (1)	IN154926B (da)
IT (1)	IT1209373B (da)
LU (1)	LU82950A1 (da)
NL (1)	NL182565C (da)
NO (1)	NO803521L (da)
NZ (1)	NZ195596A (da)
PH (1)	PH16666A (da)
PL (1)	PL132354B1 (da)
PT (1)	PT72090B (da)
SE (1)	SE448732B (da)
SU (1)	SU1042620A3 (da)
YU (1)	YU41953B (da)
ZA (1)	ZA807293B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8300728D0 (en) *	1983-01-12	1983-02-16	Erba Farmitalia	Substituted carboxy-thiazolo / 3 2 - a / pyrimidine derivatives
US4457932A (en) *	1983-07-22	1984-07-03	Bristol-Myers Company	Anti-ulcer agents
GB8422916D0 (en) *	1984-09-11	1984-10-17	May & Baker Ltd	Compositions of matter
JP2690742B2 (ja) *	1987-03-30	1997-12-17	第一製薬株式会社	複素環アミン誘導体
DE68926473T2 (de) *	1988-03-28	1996-10-02	Janssen Pharmaceutica Nv	Mittel zur Konservierung oder Wiederherstellung der gesunden Haut
TWI500623B (zh) *	2009-10-13	2015-09-21	Torrent Pharmaceuticals Ltd	新穎稠合噻唑及噁唑嘧啶酮

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1331059A (en) *	1971-04-19	1973-09-19	Lilly Industries Ltd	Pyrimidotriazinone compounds
US4041163A (en) *	1976-03-29	1977-08-09	Pfizer Inc.	N-(5-Tetrazolyl)-4-oxo-4H-pyrimido(2,1-b)benzothiazole-3-carboxamide antiallergy agents
DE2810863A1 (de) *	1978-03-13	1979-09-27	Boehringer Mannheim Gmbh	1-oxo-1h-pyrimido eckige klammer auf 6,1-b eckige klammer zu benzthiazol-derivate und verfahren zu ihrer herstellung
US4223031A (en) *	1978-05-05	1980-09-16	Mead Johnson & Company	Azolopyrimidinones

1980
- 1980-09-30 DK DK413180A patent/DK151811C/da not_active IP Right Cessation
- 1980-10-15 IN IN760/DEL/80A patent/IN154926B/en unknown
- 1980-11-17 SU SU803212053A patent/SU1042620A3/ru active
- 1980-11-18 AR AR283276A patent/AR228859A1/es active
- 1980-11-18 GB GB8036904A patent/GB2063862B/en not_active Expired
- 1980-11-18 CS CS807820A patent/CS241476B2/cs unknown
- 1980-11-18 HU HU80802755A patent/HU179091B/hu not_active IP Right Cessation
- 1980-11-19 EG EG723/80A patent/EG14929A/xx active
- 1980-11-19 CH CH8567/80A patent/CH649299A5/fr not_active IP Right Cessation
- 1980-11-20 GR GR63413A patent/GR72132B/el unknown
- 1980-11-20 YU YU2950/80A patent/YU41953B/xx unknown
- 1980-11-20 NZ NZ195596A patent/NZ195596A/en unknown
- 1980-11-21 FR FR8024822A patent/FR2470132A1/fr active Granted
- 1980-11-21 IT IT8026176A patent/IT1209373B/it active
- 1980-11-21 NO NO803521A patent/NO803521L/no unknown
- 1980-11-21 ES ES497066A patent/ES8203363A1/es not_active Expired
- 1980-11-21 CA CA000365258A patent/CA1143731A/en not_active Expired
- 1980-11-21 SE SE8008189A patent/SE448732B/sv not_active IP Right Cessation
- 1980-11-21 IE IE2418/80A patent/IE50404B1/en unknown
- 1980-11-21 FI FI803628A patent/FI67706C/fi not_active IP Right Cessation
- 1980-11-21 NL NLAANVRAGE8006362,A patent/NL182565C/xx not_active IP Right Cessation
- 1980-11-21 DE DE3043979A patent/DE3043979C2/de not_active Expired
- 1980-11-21 IL IL61535A patent/IL61535A/xx unknown
- 1980-11-21 LU LU82950A patent/LU82950A1/fr unknown
- 1980-11-21 JP JP16450280A patent/JPS5687586A/ja active Granted
- 1980-11-21 ZA ZA00807293A patent/ZA807293B/xx unknown
- 1980-11-21 DE DE3050491A patent/DE3050491C2/de not_active Expired
- 1980-11-21 PT PT72090A patent/PT72090B/pt not_active IP Right Cessation
- 1980-11-21 AU AU64595/80A patent/AU520995B2/en not_active Ceased
- 1980-11-21 AT AT0570780A patent/AT380883B/de not_active IP Right Cessation
- 1980-11-21 PH PH24891A patent/PH16666A/en unknown
- 1980-11-21 GT GT198066458A patent/GT198066458A/es unknown
- 1980-11-21 DD DD80225391A patent/DD154608A5/de not_active IP Right Cessation
- 1980-11-22 KR KR1019800004474A patent/KR830004322A/ko not_active Ceased
- 1980-11-22 PL PL1980228008A patent/PL132354B1/pl unknown
- 1980-11-24 BE BE0/202915A patent/BE886319A/fr not_active IP Right Cessation
1982
- 1982-09-13 AR AR290628A patent/AR231296A1/es active

Also Published As

Publication number	Publication date
PT72090A (en)	1980-12-01
FI67706B (fi)	1985-01-31
FR2470132A1 (fr)	1981-05-29
DE3043979A1 (de)	1981-09-03
PL132354B1 (en)	1985-02-28
ZA807293B (en)	1981-12-30
PL228008A1 (da)	1981-12-11
IL61535A (en)	1984-06-29
IE50404B1 (en)	1986-04-16
CH649299A5 (fr)	1985-05-15
FI803628L (fi)	1981-05-24
AR231296A1 (es)	1984-10-31
DK151811B (da)	1988-01-04
NL8006362A (nl)	1981-06-16
CS782080A2 (en)	1985-06-13
DD154608A5 (de)	1982-04-07
GT198066458A (es)	1982-05-15
CA1143731A (en)	1983-03-29
AT380883B (de)	1986-07-25
NO803521L (no)	1981-05-25
GR72132B (da)	1983-09-19
IN154926B (da)	1984-12-22
SE448732B (sv)	1987-03-16
KR830004322A (ko)	1983-07-09
SU1042620A3 (ru)	1983-09-15
IT8026176A0 (it)	1980-11-21
HU179091B (en)	1982-08-28
FI67706C (fi)	1985-05-10
YU41953B (en)	1988-02-29
AR228859A1 (es)	1983-04-29
SE8008189L (sv)	1981-05-24
PT72090B (en)	1981-09-29
LU82950A1 (fr)	1981-06-04
ES497066A0 (es)	1982-04-01
IT1209373B (it)	1989-07-16
GB2063862A (en)	1981-06-10
GB2063862B (en)	1983-06-22
IE802418L (en)	1981-05-23
DE3050491C2 (de)	1985-10-10
YU295080A (en)	1983-06-30
NL182565C (nl)	1988-04-05
PH16666A (en)	1983-12-13
CS241476B2 (en)	1986-03-13
ATA570780A (de)	1985-12-15
EG14929A (en)	1989-01-30
IL61535A0 (en)	1980-12-31
JPS617432B2 (da)	1986-03-06
BE886319A (fr)	1981-05-25
FR2470132B1 (da)	1983-07-29
AU6459580A (en)	1981-05-28
ES8203363A1 (es)	1982-04-01
DE3043979C2 (de)	1986-08-21
NZ195596A (en)	1984-05-31
AU520995B2 (en)	1982-03-11
NL182565B (nl)	1987-11-02
DK151811C (da)	1988-06-06
JPS5687586A (en)	1981-07-16

Legal Events

Date	Code	Title	Description
1991-05-27	PBP	Patent lapsed

Publication	Publication Date	Title
DK29681A (da)	1981-01-22	Fremgangsmaade til fremstilling af immunogammaglobulin
NO149389C (no)	1984-04-11	Fremgangsmaate til fremstilling av 4,1`,6`-triklor-4,1`,6`-trideoksy-galaktosukrose
DK311580A (da)	1981-01-22	Fremgangsmaade til fremstilling af oxoalkylxanthiner
DK222980A (da)	1980-11-24	Fremgangsmaade til fremstilling af sulfonamidderivater
DK4280A (da)	1980-07-13	Fremgangsmaade til fremstilling af pleuromutilinderivater
DK274580A (da)	1980-12-29	Fremgangsmaade til fremstilling af tripeptidamider
DK149623C (da)	1987-06-01	Fremgangsmaade til fremstilling af alfa-hydroxycarboxylsyreamider
DK289480A (da)	1981-01-06	Fremgangsmaade til fremstilling af o-substituerede ketoximer
MX6160E (es)	1984-11-29	Procedimiento para la preparacion de n-(2-fenil 2-hidroxietil)-1,1-dimetil-3-(4-fenil sustituidas)propilaminas
DK149856C (da)	1987-05-25	Fremgangsmaade til fremstilling af 1,3-di- eller 1,3,8-trisubstituerede xanthiner eller fysiologisk acceptable salte deraf
DK341281A (da)	1982-02-01	Fremgangsmaade til fremstilling af 3,3-dialkyldenzodiazepinderivater eller syreadditionssalte deraf samt ved fremgangsmaaden som mellemprodukter anvendelige forbindelrser
DK343280A (da)	1981-02-11	Fremgangsmaade til fremstilling af 7-hydroxycumaraner
DK262180A (da)	1980-12-21	Fremgangsmaade til fremstilling af alkyl-2-chlorpropionater
DK334580A (da)	1981-02-04	Fremgangsmaade til fremstilling af substituerede tetraazatricycler
DK117779A (da)	1979-09-24	Fremgangsmaade til fremstilling af 2,6-dialkoxybenzamider
DK215980A (da)	1980-11-17	Fremgangsmaade til fremstilling af sulfonamidderivater
DK187980A (da)	1980-11-05	Fremgangsmaade til fremstilling af benzimidazolderivater
NO820281L (no)	1982-08-03	Fremgangsmaate ved fremstilling av n-(halogenmethyl)-acylamider
DK274680A (da)	1980-12-29	Fremgangsmaade til fremstilling af tripeptidamider
DK173379A (da)	1979-10-29	Fremgangsmaade til fremstilling af 6alfa-halogen-3-keto-delta 1,4-pregnadienderivater
NO150601C (no)	1984-11-14	Fremgangsmaate ved fremstilling av 2`-6`-dialkyl-n-alkoxymethyl-2-klor-acetanilider.
DK338480A (da)	1981-02-10	Fremgangsmaade til fremstilling af pyrrolidinderivater
NO153100C (no)	1986-01-15	Fremgangsmaate ved fremstilling av n-(halogenmethyl)-acylamider.
DK318280A (da)	1981-01-26	Fremgangsmaade til fremstilling af naphthyridinderivater
DK156427C (da)	1990-01-22	Fremgangsmaade til fremstilling af n-alkylarylaminer