DK414182A - Bis-thymosin-alfa1-forbindelser - Google Patents

Bis-thymosin-alfa1-forbindelser Download PDF

Info

Publication number: DK414182A
Authority: DK; Denmark
Prior art keywords: alpha; carbon atoms; bis; relations; groups
Prior art date: 1981-09-18

Application number

DK414182A

Other languages

English (en)

Other versions

DK166391C (da

DK166391B (da

Inventor

Christian Birr

Original Assignee

Max Planck Gesellschaft

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-09-18

Filing date

1982-09-16

Publication date

1983-03-19

1982-09-16 Application filed by Max Planck Gesellschaft filed Critical Max Planck Gesellschaft

1983-03-19 Publication of DK414182A publication Critical patent/DK414182A/da

1993-05-10 Publication of DK166391B publication Critical patent/DK166391B/da

1993-09-27 Application granted granted Critical

1993-09-27 Publication of DK166391C publication Critical patent/DK166391C/da

Links

229960004231 thymalfasin Drugs 0.000 title 1
125000004432 carbon atom Chemical group C* 0.000 abstract 3
150000001875 compounds Chemical class 0.000 abstract 2
125000006239 protecting group Chemical group 0.000 abstract 2
150000001413 amino acids Chemical class 0.000 abstract 1
230000008878 coupling Effects 0.000 abstract 1
238000010168 coupling process Methods 0.000 abstract 1
238000005859 coupling reaction Methods 0.000 abstract 1
125000000524 functional group Chemical group 0.000 abstract 1
238000010647 peptide synthesis reaction Methods 0.000 abstract 1
239000002798 polar solvent Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57581—Thymosin; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/837—Lymph; lymph-glands; thymus
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/18—Thymus derived hormone or factor; related peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Immunology (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Toxicology (AREA)
Endocrinology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

DK414182A 1981-09-18 1982-09-16 Analogifremgangsmaade til fremstilling af bis-thymosin-alfa1-forbindelser DK166391C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE3137231		1981-09-18
DE19813137231 DE3137231A1 (de)	1981-09-18	1981-09-18	Bis-thymosin(alpha)(pfeil abwaerts)1(pfeil abwaerts)-verbindungen

Publications (3)

Publication Number	Publication Date
DK414182A true DK414182A (da)	1983-03-19
DK166391B DK166391B (da)	1993-05-10
DK166391C DK166391C (da)	1993-09-27

Family

ID=6142082

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK414182A DK166391C (da)	1981-09-18	1982-09-16	Analogifremgangsmaade til fremstilling af bis-thymosin-alfa1-forbindelser

Country Status (8)

Country	Link
US (1)	US4396605A (da)
EP (1)	EP0075776B1 (da)
JP (2)	JPS5869854A (da)
AT (1)	ATE10189T1 (da)
AU (1)	AU531708B2 (da)
CA (1)	CA1246547A (da)
DE (2)	DE3137231A1 (da)
DK (1)	DK166391C (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3137231A1 (de) *	1981-09-18	1983-04-14	Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen	Bis-thymosin(alpha)(pfeil abwaerts)1(pfeil abwaerts)-verbindungen
US4504415A (en) *	1983-04-04	1985-03-12	Hoffman-La Roche Inc.	Synthesis of thymosin α1 and desacetyl thymosin α1
DE3633651A1 (de) *	1986-10-03	1988-04-14	Alfred Dr Dick	Verwendung von fraktionen aus thymus- und milzextrakten zur behandlung der psoriasis
US5807830A (en) *	1987-12-30	1998-09-15	Cytoven J.V.	Method for treatment of purulent inflammatory diseases
US5728680A (en)	1987-12-30	1998-03-17	Cytoven J.V.	Methods for normalizing numbers of lymphocytes
US5811399A (en) *	1988-12-14	1998-09-22	Cytran, Inc.	Pharmaceutical dipeptide compositions and methods of use thereof: immunodepressants
US5770576A (en) *	1989-08-30	1998-06-23	Cytran, Inc.	Pharmaceutical dipeptide compositions and methods of use thereof: systemic toxicity
US6100380A (en) *	1991-10-28	2000-08-08	Cytran, Inc.	Immunomodulating peptides and methods of use
US6066622A (en)	1991-10-28	2000-05-23	Cytran, Inc.	Immunomodulating peptides and methods of use
IT1256925B (it) *	1992-08-05	1995-12-27		Impiego di frammenti o/e di derivati della timosina alfa 1.
CN1058500C (zh) *	1993-02-03	2000-11-15	施塞克龙药品公司	胸腺素α－1衍生物
WO1994020063A2 (en) *	1993-03-04	1994-09-15	Cytoven International N.V.	Pharmaceutical tryptophan containing dipeptide compositions and methods of use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH633258A5 (en) *	1976-10-28	1982-11-30	Hoffmann La Roche	Process for preparing thymosin alpha 1
DE2919592A1 (de) *	1979-05-15	1981-01-15	Max Planck Gesellschaft	Verfahren zur herstellung von thymosin- alpha 1 und derivaten davon
EP0033384B1 (de) *	1980-01-18	1984-02-15	Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.	Thymosin-alpha-1-Fragmente enthaltende Arzneimittel mit immunstimulierender Wirkung, und Thymosin-alpha-1-Fragmente
DE3137231A1 (de) *	1981-09-18	1983-04-14	Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen	Bis-thymosin(alpha)(pfeil abwaerts)1(pfeil abwaerts)-verbindungen

1981
- 1981-09-18 DE DE19813137231 patent/DE3137231A1/de not_active Withdrawn
1982
- 1982-04-12 US US06/367,817 patent/US4396605A/en not_active Expired - Lifetime
- 1982-09-13 DE DE8282108438T patent/DE3261206D1/de not_active Expired
- 1982-09-13 EP EP82108438A patent/EP0075776B1/de not_active Expired
- 1982-09-13 AT AT82108438T patent/ATE10189T1/de active
- 1982-09-16 JP JP57159688A patent/JPS5869854A/ja active Granted
- 1982-09-16 CA CA000411554A patent/CA1246547A/en not_active Expired
- 1982-09-16 AU AU88473/82A patent/AU531708B2/en not_active Ceased
- 1982-09-16 DK DK414182A patent/DK166391C/da active
1986
- 1986-12-17 JP JP61299062A patent/JPS62142200A/ja active Granted

Also Published As

Publication number	Publication date
AU531708B2 (en)	1983-09-01
DE3261206D1 (en)	1984-12-13
EP0075776A1 (de)	1983-04-06
DK166391C (da)	1993-09-27
US4396605A (en)	1983-08-02
JPH0374680B2 (da)	1991-11-27
ATE10189T1 (de)	1984-11-15
JPS6244000B2 (da)	1987-09-17
CA1246547A (en)	1988-12-13
JPS5869854A (ja)	1983-04-26
EP0075776B1 (de)	1984-11-07
DK166391B (da)	1993-05-10
AU8847382A (en)	1983-05-12
DE3137231A1 (de)	1983-04-14
JPS62142200A (ja)	1987-06-25

Publication	Publication Date	Title
ATE10189T1 (de)	1984-11-15	Bis-thymosin alpha 1-verbindungen.
KR850003417A (ko)	1985-06-17	폴리펩티드의 제조방법
ES528649A0 (es)	1985-05-01	Un polipeptido sintetico
BR1100650A (pt)	2000-08-08	Proteìnas de superfìcie cd44 variantes, sequências de dna que as codificam, anticorpos contra estas proteìnas, bem como a sua utilização no diagnóstico e na terapia
ES2147178T3 (es)	2000-09-01	Dominio de union a cd2 del antigeno 3 asociado con la funcion linfocitica.
FI894799A0 (fi)	1989-10-10	Nya proteolytiska enzymer och deras anvaendning i tvaettmedel.
IL100343A0 (en)	1992-09-06	G protein coupled glutamate receptors
ATE63126T1 (de)	1991-05-15	Tetra- und penta-peptide mit der sequenz lysylarginyl-aspartyl, und ihre verwendung als antithrombotika.
ES2095255T3 (es)	1997-02-16	Analogos de sustitucion de peptidos magainina.
ATE121754T1 (de)	1995-05-15	Vakzine gegen bordetella.
ZA835951B (en)	1984-04-25	Novel polypeptide having an action on the immunological system,processes for its isolation and purification,its use,agents containing this compound,and its cleavage products,their use and agents containing these products
KR830004223A (ko)	1983-07-09	싸이클 헥사펩티드 소마토스테틴 유사체의 제조방법
IT1164239B (it)	1987-04-08	Un retro-inverso analogo del decapeptide (5-14)dell'angiotensinogeno equino inibitore specifico della renina con elevata resistenza all'idrolisi enzimatica
GB1294771A (en)	1972-11-01	Thyrocalcitonin derivative
DK250287A (da)	1987-05-18	Polypeptidfremstilling
KR850007802A (ko)	1985-12-09	펩타이드의 제조방법
EP0178676A3 (en)	1988-08-17	Antigenic peptide compounds
FR1251313A (fr)	1961-01-20	Perfectionnements aux joints d'étanchéité, particulièrement aux joints de dilatation et de retrait
ES2051152B1 (es)	1994-12-16	Procedimiento de sistesis de peptidos con capacidad de detectar anticuerpos anti-virus de la hepatitis c (vhc) en suero de individuos afectados.
ATE20669T1 (de)	1986-07-15	Antigene lineare peptidverbindungen.
ATE50036T1 (de)	1990-02-15	Dichtung mit ring zum axialdruckausgleich.
SE8503248D0 (sv)	1985-07-01	Arrangemang vid slanganslutning
JPS5340712A (en)	1978-04-13	Isolation and purification of alpha-and omega-isomers of acidic amino acid or peptide having acidic amino acid unit