DK4314005T3 - Glucocorticoidreceptoragonister - Google Patents

Glucocorticoidreceptoragonister

Info

Publication number
DK4314005T3
DK4314005T3 DK22715884.7T DK22715884T DK4314005T3 DK 4314005 T3 DK4314005 T3 DK 4314005T3 DK 22715884 T DK22715884 T DK 22715884T DK 4314005 T3 DK4314005 T3 DK 4314005T3
Authority
DK
Denmark
Prior art keywords
receptoragonists
glucocorticoid
glucocorticoid receptoragonists
Prior art date
Application number
DK22715884.7T
Other languages
English (en)
Inventor
Adel Ahmed Rashad Ahmed
Joshua Ryan Clayton
Jose Eduardo Lopez
William Thomas Mcmillen
Ryan Edward Stites
Takako Wilson
Jacqueline Mary Wurst
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of DK4314005T3 publication Critical patent/DK4314005T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK22715884.7T 2021-03-23 2022-03-22 Glucocorticoidreceptoragonister DK4314005T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163164613P 2021-03-23 2021-03-23
US202163260451P 2021-08-20 2021-08-20
PCT/US2022/021299 WO2022204108A1 (en) 2021-03-23 2022-03-22 Glucocorticoid receptor agonists

Publications (1)

Publication Number Publication Date
DK4314005T3 true DK4314005T3 (da) 2026-05-11

Family

ID=81325459

Family Applications (1)

Application Number Title Priority Date Filing Date
DK22715884.7T DK4314005T3 (da) 2021-03-23 2022-03-22 Glucocorticoidreceptoragonister

Country Status (28)

Country Link
US (3) US11787834B2 (da)
EP (2) EP4785999A2 (da)
JP (2) JP7706565B2 (da)
KR (1) KR102896688B1 (da)
AU (1) AU2022242757B2 (da)
BR (1) BR112023016448A2 (da)
CA (1) CA3209170A1 (da)
CL (1) CL2023002809A1 (da)
CO (1) CO2023012249A2 (da)
CR (1) CR20230451A (da)
DK (1) DK4314005T3 (da)
DO (1) DOP2023000201A (da)
EC (1) ECSP23071886A (da)
ES (1) ES3070570T3 (da)
FI (1) FI4314005T3 (da)
HR (1) HRP20260586T1 (da)
IL (1) IL305277A (da)
JO (1) JOP20230226A1 (da)
LT (1) LT4314005T (da)
MA (1) MA63945B1 (da)
MX (1) MX2023011279A (da)
PE (1) PE20240889A1 (da)
PL (1) PL4314005T3 (da)
PT (1) PT4314005T (da)
RS (1) RS68044B1 (da)
SI (1) SI4314005T1 (da)
TW (1) TWI899455B (da)
WO (1) WO2022204108A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR125084A1 (es) * 2021-03-23 2023-06-07 Lilly Co Eli Agonistas del receptor de glucocorticoides novedosos
CN119744180A (zh) * 2022-05-13 2025-04-01 伊莱利利公司 人肿瘤坏死因子α抗体糖皮质激素缀合物
WO2023235738A1 (en) * 2022-06-02 2023-12-07 Eli Lilly And Company Human interleukin-4 receptor alpha antibody glucocorticoid conjugates
JP2025532110A (ja) * 2022-09-22 2025-09-29 イーライ リリー アンド カンパニー グルココルチコイド受容体アゴニスト
EP4635969A4 (en) * 2022-12-16 2026-06-10 Tianjin Pharmaceutical Biotechnology Co Ltd NEW GLUCOCORTICOID, ITS PREPARATION PROCESS AND ITS USE

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004071389A2 (en) * 2003-02-15 2004-08-26 Glaxo Group Limited Non-steroidal infalmmation inhibitors
AU2006259604A1 (en) 2005-06-14 2006-12-28 Gilead Sciences, Inc. Substituted phenylphosphates as mutual prodrugs of steroids and beta -agonists for the treatment of pulmonary inflammation and bronchoconstriction
EP2225256B1 (en) 2007-11-30 2013-01-09 Pfizer Limited Novel glucocorticoid receptor agonists
CN101970452A (zh) 2007-12-21 2011-02-09 先灵公司 C20-c21取代的糖皮质激素受体激动剂
BRPI0907789A2 (pt) 2008-02-27 2019-01-22 Astrazeneca Ab derivaldos 16-alfa e 17-alfa de glicocorticosteroides e seus usos
WO2017062271A2 (en) 2015-10-06 2017-04-13 Merck Sharp & Dohme Corp. Antibody drug conjugate for anti-inflammatory applications
EP3407916B1 (en) 2016-01-29 2023-12-20 Merck Sharp & Dohme LLC Phosphonate linkers and their use to facilitate cellular retention of compounds
RS62040B1 (sr) * 2016-06-02 2021-07-30 Abbvie Inc Agonist receptora glukokortikoida i njegovi imunokonjugati
CA3042428A1 (en) 2016-11-08 2018-05-17 Regeneron Pharmaceuticals, Inc. Steroids and protein-conjugates thereof
EP3658192B1 (en) * 2017-12-01 2021-04-28 AbbVie Inc. Glucocorticoid receptor agonist and immunoconjugates thereof
RU2020117156A (ru) 2017-12-01 2022-01-04 Эббви Инк. Конъюгаты анти-cd40 антитела и лекарственного средства
CN116096413A (zh) 2020-04-22 2023-05-09 伊穆奈克斯特股份有限公司 抗人vista抗体及其用途
EP4271387A4 (en) * 2021-01-07 2026-01-28 Immunext Inc NEW STEROID PAYLOAD, STEROID BINDERS, CONTAINERS AND ASSOCIATED USES
JP2024531480A (ja) * 2021-08-26 2024-08-29 デュアリティ バイオロジクス（スーチョウ）カンパニー，リミティド ステロイド化合物及びそのコンジュゲート

Also Published As

Publication number Publication date
EP4314005A1 (en) 2024-02-07
PL4314005T3 (pl) 2026-06-08
US12404298B2 (en) 2025-09-02
MX2023011279A (es) 2023-10-04
ES3070570T3 (en) 2026-06-16
TW202304462A (zh) 2023-02-01
JP7706565B2 (ja) 2025-07-11
EP4785999A2 (en) 2026-08-05
HRP20260586T1 (hr) 2026-06-05
IL305277A (en) 2023-10-01
KR102896688B1 (ko) 2025-12-08
PE20240889A1 (es) 2024-04-24
JOP20230226A1 (ar) 2023-09-19
BR112023016448A2 (pt) 2023-10-24
PT4314005T (pt) 2026-05-04
CR20230451A (es) 2023-10-11
LT4314005T (lt) 2026-05-25
JP2024510774A (ja) 2024-03-11
MA63945B1 (fr) 2026-04-30
US11787834B2 (en) 2023-10-17
US20250353874A1 (en) 2025-11-20
JP2025143371A (ja) 2025-10-01
AU2022242757A1 (en) 2023-08-24
ECSP23071886A (es) 2023-10-31
AU2022242757B2 (en) 2024-12-05
US20240018182A1 (en) 2024-01-18
TWI899455B (zh) 2025-10-01
KR20230145487A (ko) 2023-10-17
SI4314005T1 (sl) 2026-07-31
CO2023012249A2 (es) 2023-09-29
RS68044B1 (sr) 2026-05-29
WO2022204108A1 (en) 2022-09-29
DOP2023000201A (es) 2023-10-15
US20220324904A1 (en) 2022-10-13
CA3209170A1 (en) 2022-09-29
EP4314005B1 (en) 2026-02-25
FI4314005T3 (fi) 2026-05-05
CL2023002809A1 (es) 2024-04-26

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