DK437788A - Derivater af 2-((4-piperidinyl)methyl)-1,2,3,4-tetrahydro-9h-pyrido(3,4-b)indol til terapeutisk anvendelse samt fremgangsmaade til fremstilling af saadanne derivater - Google Patents

Derivater af 2-((4-piperidinyl)methyl)-1,2,3,4-tetrahydro-9h-pyrido(3,4-b)indol til terapeutisk anvendelse samt fremgangsmaade til fremstilling af saadanne derivater

Info

Publication number
DK437788A
DK437788A DK437788A DK437788A DK437788A DK 437788 A DK437788 A DK 437788A DK 437788 A DK437788 A DK 437788A DK 437788 A DK437788 A DK 437788A DK 437788 A DK437788 A DK 437788A
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DK
Denmark
Prior art keywords
group
derivatives
denotes
formula
pyrido
Prior art date
Application number
DK437788A
Other languages
English (en)
Other versions
DK437788D0 (da
Inventor
Mireille Sevrin
Pascal George
Jacques Menin
Claude Morel
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of DK437788D0 publication Critical patent/DK437788D0/da
Publication of DK437788A publication Critical patent/DK437788A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK437788A 1987-08-07 1988-08-05 Derivater af 2-((4-piperidinyl)methyl)-1,2,3,4-tetrahydro-9h-pyrido(3,4-b)indol til terapeutisk anvendelse samt fremgangsmaade til fremstilling af saadanne derivater DK437788A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8711291A FR2619111B1 (fr) 1987-08-07 1987-08-07 Derives de (piperidinyl-4)methyl-2 tetrahydro-1,2,3,4 9h-pyrido (3,4-b) indole, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
DK437788D0 DK437788D0 (da) 1988-08-05
DK437788A true DK437788A (da) 1989-02-07

Family

ID=9354027

Family Applications (1)

Application Number Title Priority Date Filing Date
DK437788A DK437788A (da) 1987-08-07 1988-08-05 Derivater af 2-((4-piperidinyl)methyl)-1,2,3,4-tetrahydro-9h-pyrido(3,4-b)indol til terapeutisk anvendelse samt fremgangsmaade til fremstilling af saadanne derivater

Country Status (17)

Country Link
US (1) US4977159A (da)
EP (1) EP0302788B1 (da)
JP (1) JPS6466185A (da)
KR (1) KR890003756A (da)
AT (1) ATE72436T1 (da)
AU (1) AU597188B2 (da)
DE (1) DE3868301D1 (da)
DK (1) DK437788A (da)
FI (1) FI883669A7 (da)
FR (1) FR2619111B1 (da)
GR (1) GR3003920T3 (da)
HU (1) HU198931B (da)
IL (1) IL87343A0 (da)
NO (1) NO166129C (da)
NZ (1) NZ225706A (da)
PT (1) PT88206B (da)
ZA (1) ZA885788B (da)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4978669A (en) * 1989-06-08 1990-12-18 Neurex Corporation Method of suppressing appetite by administration of tetrahydro-beta-carboline derivatives
US5229517A (en) * 1990-09-27 1993-07-20 Hoechst-Roussel Pharmaceuticals Incorporated 2-(4-Piperindinyl)-1H-pyrido[4,3-B]indol-1-ones and related compounds
US5102889B1 (en) * 1990-09-27 1993-05-11 2-(4-piperidinyl)-1h-pyrido(4,3-b)indol-1-ones and related compounds
US5455254A (en) * 1991-02-15 1995-10-03 Mondadori; Cesare Substituted benzofuranylpiperidine as a nootropic agent
RU2095339C1 (ru) * 1991-10-17 1997-11-10 Циба-Гейги АГ Производные гидрохинона в свободном виде или в виде соли, способы их получения, производные пиперидина и способы их получения
US5693807A (en) * 1992-10-14 1997-12-02 Ciba-Geigy Corporation Substituted hydroquinone derivatives
FR2715659B1 (fr) * 1994-02-03 1996-03-22 Synthelabo Dérivés de 3-(2-aminoéthyl)-4-[3-(trifluorométhyl)benzoyl]-3,4-dihydro-2H-1,4-benzoxazine, leur préparation et leur application en thérapeutique.
CN1109880A (zh) * 1994-02-03 1995-10-11 合成实验室公司 3-(2-氨基乙基)-4-[3-(三氟甲基)苯甲酰基]-3，4-二氢-2h-1，4-苯并噁嗪衍生物、制备及其应用
AU3831495A (en) * 1994-10-20 1996-05-15 American Home Products Corporation Indole derivatives useful as serotonergic agents
US6255302B1 (en) 1998-12-17 2001-07-03 American Home Products Corporation 1,4-piperazine derivatives
CO5180550A1 (es) 1999-04-19 2002-07-30 Smithkline Beecham Corp Inhibidores de fab i
CO5370679A1 (es) * 1999-06-01 2004-02-27 Smithkline Beecham Corp Inhibidores fab 1
US6762201B1 (en) 1999-10-08 2004-07-13 Affinium Pharmaceuticals, Inc. Fab I inhibitors
US6730684B1 (en) 1999-10-08 2004-05-04 Affinium Pharmaceuticals, Inc. Fab I inhibitors
HU230030B1 (hu) * 1999-10-08 2015-05-28 Debiopharm International Sa Fab I inhibitorok
DE60037345T2 (de) 1999-12-10 2008-11-13 Pfizer Products Inc., Groton Pyrrolo(2,3-d)pyrimidin-Verbindungen
EP1560584B1 (en) * 2001-04-06 2009-01-14 Affinium Pharmaceuticals, Inc. Fab i inhibitors
AU2002360561A1 (en) * 2001-12-11 2003-06-23 Sepracor, Inc. 4-substituted piperidines, and methods of use thereof
AU2003278529A1 (en) * 2002-11-21 2004-06-15 Pfizer Products Inc. 3-amino-piperidine derivatives and processes for their preparation
EP1575951B1 (en) 2002-12-06 2014-06-25 Debiopharm International SA Heterocyclic compounds, methods of making them and their use in therapy
WO2004082586A2 (en) 2003-03-17 2004-09-30 Affinium Pharmaceuticals, Inc. Phamaceutical compositions comprising inhibitors of fab i and further antibiotics
JP2006525347A (ja) * 2003-04-29 2006-11-09 オシエント ファーマシューティカルズ 抗生テトラヒドロ−β−カルボリン誘導体
DK1828167T3 (da) 2004-06-04 2014-10-20 Debiopharm Int Sa Acrylamidderivater som antibiotiske midler
JP5468899B2 (ja) 2006-07-20 2014-04-09 アフィニウム ファーマシューティカルズ， インク． Ｆａｂｉインヒビターとしてのアクリルアミド誘導体
EP2125802A4 (en) 2007-02-16 2014-08-20 Debiopharm Int Sa SALTS, PRODRUGS AND POLYMORPHES OF FAB I INHIBITORS
AU2013279021C1 (en) 2012-06-19 2017-03-16 Debiopharm International Sa Prodrug derivatives of (E)-N-methyl-N-((3-methylbenzofuran-2-yl)methyl)-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)acrylamide
RS61312B1 (sr) 2016-02-26 2021-02-26 Debiopharm Int Sa Lek za lečenje infekcija dijabetskog stopala
TN2021000159A1 (en) 2019-02-14 2023-04-04 Debiopharm Int Sa Afabicin formulation, method for making the same and uses thereof
SG11202113174SA (en) 2019-06-14 2021-12-30 Debiopharm Int Sa Medicament and use thereof for treating bacterial infections involving biofilm

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4539407A (en) * 1983-12-13 1985-09-03 American Home Products Corporation β-Carboline anticonvulsants
US4663456A (en) * 1985-09-16 1987-05-05 American Home Products Corporation 2-(substituted piperazinylalkyl)β-carbolines useful in treatment of psychological disorders

Also Published As

Publication number Publication date
FI883669A0 (fi) 1988-08-05
NO166129C (no) 1991-06-05
ATE72436T1 (de) 1992-02-15
HUT48242A (en) 1989-05-29
DK437788D0 (da) 1988-08-05
NZ225706A (en) 1990-04-26
FR2619111A1 (fr) 1989-02-10
FR2619111B1 (fr) 1991-01-11
NO883487L (no) 1989-02-08
EP0302788A1 (fr) 1989-02-08
IL87343A0 (en) 1989-01-31
JPS6466185A (en) 1989-03-13
HU198931B (en) 1989-12-28
AU597188B2 (en) 1990-05-24
NO883487D0 (no) 1988-08-05
ZA885788B (en) 1989-04-26
US4977159A (en) 1990-12-11
DE3868301D1 (de) 1992-03-19
PT88206B (pt) 1995-05-04
PT88206A (pt) 1989-06-30
EP0302788B1 (fr) 1992-02-05
GR3003920T3 (da) 1993-03-16
NO166129B (no) 1991-02-25
KR890003756A (ko) 1989-04-17
AU2044588A (en) 1989-02-09
FI883669A7 (fi) 1989-02-08

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Legal Events

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AHB Application shelved due to non-payment