DK443489D0 - Substituerede urinstofforbindelser, deres fremstilling og anvendelse - Google Patents

Substituerede urinstofforbindelser, deres fremstilling og anvendelse

Info

Publication number
DK443489D0
DK443489D0 DK443489A DK443489A DK443489D0 DK 443489 D0 DK443489 D0 DK 443489D0 DK 443489 A DK443489 A DK 443489A DK 443489 A DK443489 A DK 443489A DK 443489 D0 DK443489 D0 DK 443489D0
Authority
DK
Denmark
Prior art keywords
substituted
alkyl
cycloalkyl
compounds
preparation
Prior art date
Application number
DK443489A
Other languages
English (en)
Inventor
John Bondo Hansen
Original Assignee
Ferrosan As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrosan As filed Critical Ferrosan As
Priority to DK443489A priority Critical patent/DK443489D0/da
Publication of DK443489D0 publication Critical patent/DK443489D0/da
Priority to IL9544090A priority patent/IL95440A/en
Priority to IE308290A priority patent/IE69266B1/en
Priority to NZ235117A priority patent/NZ235117A/en
Priority to CA002066696A priority patent/CA2066696A1/en
Priority to ZA907111A priority patent/ZA907111B/xx
Priority to AT90610056T priority patent/ATE106885T1/de
Priority to ES90610056T priority patent/ES2054309T3/es
Priority to EP90913477A priority patent/EP0491770A1/en
Priority to PCT/DK1990/000232 priority patent/WO1991003475A1/en
Priority to AU63414/90A priority patent/AU639487B2/en
Priority to EP90610056A priority patent/EP0419397B1/en
Priority to FI921005A priority patent/FI921005A0/fi
Priority to JP2512602A priority patent/JPH05505171A/ja
Priority to HU92776A priority patent/HU208433B/hu
Priority to DE69009646T priority patent/DE69009646T2/de
Priority to DK90610056.5T priority patent/DK0419397T3/da
Priority to PT95248A priority patent/PT95248B/pt
Priority to NO920833A priority patent/NO300460B1/no
Priority to US07/947,073 priority patent/US5330990A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Treating Waste Gases (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Lubricants (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
DK443489A 1989-09-08 1989-09-08 Substituerede urinstofforbindelser, deres fremstilling og anvendelse DK443489D0 (da)

Priority Applications (20)

Application Number Priority Date Filing Date Title
DK443489A DK443489D0 (da) 1989-09-08 1989-09-08 Substituerede urinstofforbindelser, deres fremstilling og anvendelse
IL9544090A IL95440A (en) 1989-09-08 1990-08-21 N-(2-substituted phenyl)-n'-azabicycloalkyl ureas, their preparation and pharmaceutical compositions containing them
IE308290A IE69266B1 (en) 1989-09-08 1990-08-24 Substituted urea compounds and their preparation and use
NZ235117A NZ235117A (en) 1989-09-08 1990-08-31 N-azabicyclosubstituted-n'-(substituted phenyl)urea derivatives; preparatory processes and pharmaceutical compositions
DK90610056.5T DK0419397T3 (da) 1989-09-08 1990-09-06 Substituerede urinsyreforbindelser, deres fremstilling og anvendelse
EP90913477A EP0491770A1 (en) 1989-09-08 1990-09-06 Substituted urea compounds and their preparation and use
EP90610056A EP0419397B1 (en) 1989-09-08 1990-09-06 Substituted urea compounds and their preparation and use
AT90610056T ATE106885T1 (de) 1989-09-08 1990-09-06 Substituierte harnstoffverbindungen, ihre herstellung und verwendung.
ES90610056T ES2054309T3 (es) 1989-09-08 1990-09-06 Compuestos de urea sustituida y su preparacion y uso.
CA002066696A CA2066696A1 (en) 1989-09-08 1990-09-06 Substituted urea compounds and their preparation and use
PCT/DK1990/000232 WO1991003475A1 (en) 1989-09-08 1990-09-06 Substituted urea compounds and their preparation and use
AU63414/90A AU639487B2 (en) 1989-09-08 1990-09-06 Substituted urea compounds and their preparation and use
ZA907111A ZA907111B (en) 1989-09-08 1990-09-06 Substituted urea compounds and their preparation and use
FI921005A FI921005A0 (fi) 1989-09-08 1990-09-06 Substituerade karbamidfoereningar samt deras framstaellning och anvaendning.
JP2512602A JPH05505171A (ja) 1989-09-08 1990-09-06 置換尿素化合物およびその製造並びに使用
HU92776A HU208433B (en) 1989-09-08 1990-09-06 Process for producing substituted urea derivatives and pharmaceutical compositions containing them as active components
DE69009646T DE69009646T2 (de) 1989-09-08 1990-09-06 Substituierte Harnstoffverbindungen, ihre Herstellung und Verwendung.
PT95248A PT95248B (pt) 1989-09-08 1990-09-07 Processo de preparacao de compostos de ureia substituidos e de composicoes farmaceuticas que os contem
NO920833A NO300460B1 (no) 1989-09-08 1992-03-03 Analogifremgangsmåte for fremstilling av terapeutisk aktive ureaforbindelser
US07/947,073 US5330990A (en) 1989-09-08 1992-09-17 Substituted urea compounds and their preparation and use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK443489A DK443489D0 (da) 1989-09-08 1989-09-08 Substituerede urinstofforbindelser, deres fremstilling og anvendelse

Publications (1)

Publication Number Publication Date
DK443489D0 true DK443489D0 (da) 1989-09-08

Family

ID=8133482

Family Applications (2)

Application Number Title Priority Date Filing Date
DK443489A DK443489D0 (da) 1989-09-08 1989-09-08 Substituerede urinstofforbindelser, deres fremstilling og anvendelse
DK90610056.5T DK0419397T3 (da) 1989-09-08 1990-09-06 Substituerede urinsyreforbindelser, deres fremstilling og anvendelse

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK90610056.5T DK0419397T3 (da) 1989-09-08 1990-09-06 Substituerede urinsyreforbindelser, deres fremstilling og anvendelse

Country Status (18)

Country Link
US (1) US5330990A (da)
EP (2) EP0419397B1 (da)
JP (1) JPH05505171A (da)
AT (1) ATE106885T1 (da)
AU (1) AU639487B2 (da)
CA (1) CA2066696A1 (da)
DE (1) DE69009646T2 (da)
DK (2) DK443489D0 (da)
ES (1) ES2054309T3 (da)
FI (1) FI921005A0 (da)
HU (1) HU208433B (da)
IE (1) IE69266B1 (da)
IL (1) IL95440A (da)
NO (1) NO300460B1 (da)
NZ (1) NZ235117A (da)
PT (1) PT95248B (da)
WO (1) WO1991003475A1 (da)
ZA (1) ZA907111B (da)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8922622D0 (en) * 1989-10-07 1989-11-22 Wyeth John & Brother Ltd Aroylureas
DK40890D0 (da) * 1990-02-16 1990-02-16 Ferrosan As Substituerede urinstofforbindelser, deres fremstilling og anvendelse
GB9106571D0 (en) * 1991-03-27 1991-05-15 Erba Carlo Spa Derivatives of substituted imidazol-2-one and process for their preparation
FR2677019B1 (fr) * 1991-05-27 1994-11-25 Pf Medicament Nouvelles piperidines disubstituees-1,4, leur preparation et leur application en therapeutique.
GB9120628D0 (en) * 1991-09-27 1991-11-06 Fujisawa Pharmaceutical Co Pyrrolobenzoxazine derivatives and process for preparation thereof
GB9121835D0 (en) * 1991-10-15 1991-11-27 Smithkline Beecham Plc Pharmaceuticals
GB9206989D0 (en) * 1992-03-31 1992-05-13 Glaxo Group Ltd Chemical compounds
CA2133083A1 (en) * 1992-03-31 1993-10-14 Alexander W. Oxford Substituted phenylcarbamates and phenylureas, their preparation and their use as 5-ht antagonists
GB9214184D0 (en) * 1992-07-03 1992-08-12 Smithkline Beecham Plc Pharmaceuticals
GB9307400D0 (en) * 1993-04-08 1993-06-02 Smithkline Beecham Plc Compounds
US5773459A (en) * 1995-06-07 1998-06-30 Sugen, Inc. Urea- and thiourea-type compounds
DE69739869D1 (de) * 1996-03-20 2010-06-17 Univ Wake Forest Health Sciences Sigma-2 rezeptoren als biomarkierer der tumorzellenproliferation
US6676925B1 (en) 1996-03-20 2004-01-13 Wake Forest University Sigma-2 receptors as biomarkers of tumor cell proliferation
DE19643037A1 (de) * 1996-10-18 1998-04-23 Boehringer Ingelheim Kg Neue Oxadiazole, Verfahren zu ihrer Herstellung sowie deren Verwendung als Arzneimittel
US6660529B2 (en) * 1998-07-28 2003-12-09 Pe Corporation Heteroaryl substituted benzothiazole dioxetanes
US6693202B1 (en) 1999-02-16 2004-02-17 Theravance, Inc. Muscarinic receptor antagonists
UA73543C2 (uk) 1999-12-07 2005-08-15 Тераванс, Інк. Похідні сечовини, фармацевтична композиція та застосування похідного при приготуванні лікарського засобу для лікування захворювання, яке опосередковується мускариновим рецептором
DE60021282T2 (de) 1999-12-07 2006-05-18 Theravance, Inc., South San Francisco Carbamat-derivate als muscarin-rezeptor antonisten
WO2001080905A2 (en) 2000-04-27 2001-11-01 Wake Forest University Health Sciences Sigma-2 receptors as biomarkers of tumor cell proliferation
US20050069976A1 (en) * 2001-02-14 2005-03-31 Peter Lind Protein-coupled receptor
PE20040950A1 (es) 2003-02-14 2005-01-01 Theravance Inc DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
ES2329586T3 (es) 2003-11-21 2009-11-27 Theravance, Inc. Compuestos que tienen actividad agonista del receptor beta2 adrenergico y antagonista del receptor muscarino.
GB0602778D0 (en) 2006-02-10 2006-03-22 Glaxo Group Ltd Novel compound
MA37975B2 (fr) 2012-09-11 2021-03-31 Genzyme Corp Inhibiteurs de synthase de glucosylcéramide
CN114040762A (zh) 2019-02-04 2022-02-11 建新公司 使用葡糖神经酰胺合酶(gcs)的抑制剂治疗纤毛疾病
JP2023512366A (ja) 2020-02-03 2023-03-27 ジェンザイム・コーポレーション リソソーム蓄積性疾患と関連する神経学的症状を処置するための方法
AU2021311131B2 (en) 2020-07-24 2026-02-19 Genzyme Corporation Pharmaceutical compositions comprising venglustat

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0158265A2 (en) 1984-04-13 1985-10-16 Beecham Group Plc Benzamide and anilide derivatives
EP0235878A3 (en) 1986-01-16 1989-06-14 Beecham Group Plc Novel compounds
AU611976B2 (en) * 1987-12-24 1991-06-27 John Wyeth & Brother Limited Aroyl urea and carbamic acid derivatives of azabicyclo compounds
DK40890D0 (da) * 1990-02-16 1990-02-16 Ferrosan As Substituerede urinstofforbindelser, deres fremstilling og anvendelse

Also Published As

Publication number Publication date
AU639487B2 (en) 1993-07-29
PT95248B (pt) 1997-06-30
HUT61019A (en) 1992-11-30
HU208433B (en) 1993-10-28
AU6341490A (en) 1991-04-08
US5330990A (en) 1994-07-19
IE69266B1 (en) 1996-08-21
EP0491770A1 (en) 1992-07-01
DK0419397T3 (da) 1994-10-10
NZ235117A (en) 1993-02-25
EP0419397B1 (en) 1994-06-08
FI921005A7 (fi) 1992-03-06
FI921005A0 (fi) 1992-03-06
CA2066696A1 (en) 1991-03-09
NO920833L (no) 1992-03-03
DE69009646D1 (de) 1994-07-14
PT95248A (pt) 1991-05-22
EP0419397A1 (en) 1991-03-27
IE903082A1 (en) 1991-03-13
DE69009646T2 (de) 1995-01-12
JPH05505171A (ja) 1993-08-05
HU9200776D0 (en) 1992-08-28
ZA907111B (en) 1991-07-31
ES2054309T3 (es) 1994-08-01
NO920833D0 (no) 1992-03-03
IL95440A (en) 1994-07-31
WO1991003475A1 (en) 1991-03-21
IL95440A0 (en) 1991-06-30
NO300460B1 (no) 1997-06-02
ATE106885T1 (de) 1994-06-15

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Legal Events

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AHS Application shelved for other reasons than non-payment