DK465182A - Fremgangsmaade til fremstilling af substituerede 6-chlor-4-phenyl quinazolin-derivater - Google Patents

Fremgangsmaade til fremstilling af substituerede 6-chlor-4-phenyl quinazolin-derivater Download PDF

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Publication number
DK465182A
DK465182A DK465182A DK465182A DK465182A DK 465182 A DK465182 A DK 465182A DK 465182 A DK465182 A DK 465182A DK 465182 A DK465182 A DK 465182A DK 465182 A DK465182 A DK 465182A
Authority
DK
Denmark
Prior art keywords
chlor
procedure
quinazoline derivatives
image
preparing substituted
Prior art date
Application number
DK465182A
Other languages
English (en)
Other versions
DK156063B (da
DK156063C (da
Inventor
Andre Hallot
Kathleen Biziere
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of DK465182A publication Critical patent/DK465182A/da
Publication of DK156063B publication Critical patent/DK156063B/da
Application granted granted Critical
Publication of DK156063C publication Critical patent/DK156063C/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C07D239/84—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Luminescent Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Pyrrole Compounds (AREA)
DK465182A 1981-10-21 1982-10-20 Analogifremgangsmaade til fremstilling af 2-substituerede 6-chlor-4-phenylquinazolin-derivater DK156063C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8119767A FR2514765A1 (fr) 1981-10-21 1981-10-21 Nouveaux derives de la phenyl-4 quinazoline actifs sur le systeme nerveux central
FR8119767 1981-10-21

Publications (3)

Publication Number Publication Date
DK465182A true DK465182A (da) 1983-04-22
DK156063B DK156063B (da) 1989-06-19
DK156063C DK156063C (da) 1989-11-13

Family

ID=9263248

Family Applications (1)

Application Number Title Priority Date Filing Date
DK465182A DK156063C (da) 1981-10-21 1982-10-20 Analogifremgangsmaade til fremstilling af 2-substituerede 6-chlor-4-phenylquinazolin-derivater

Country Status (24)

Country Link
US (1) US4499092A (da)
EP (1) EP0079810B1 (da)
JP (1) JPS5888369A (da)
KR (1) KR880001077B1 (da)
AT (1) ATE17576T1 (da)
AU (1) AU551938B2 (da)
CA (1) CA1236102A (da)
CS (1) CS229692B2 (da)
DD (1) DD210040A5 (da)
DE (1) DE3268699D1 (da)
DK (1) DK156063C (da)
ES (1) ES516694A0 (da)
FI (1) FI73982C (da)
FR (1) FR2514765A1 (da)
GR (1) GR76535B (da)
HU (1) HU187579B (da)
IE (1) IE53653B1 (da)
IL (1) IL66960A0 (da)
NO (1) NO164167C (da)
NZ (1) NZ202237A (da)
PT (1) PT75667B (da)
SU (1) SU1299511A3 (da)
YU (1) YU43528B (da)
ZA (1) ZA827516B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2521144A1 (fr) * 1982-02-08 1983-08-12 Sanofi Sa Nouveaux derives de la piperazinyl-2 phenyl-4 quinazoline possedant des proprietes antidepressives, methode de preparation desdits composes et medicaments en contenant
WO1994007498A1 (fr) * 1992-10-07 1994-04-14 Sumitomo Pharmaceuticals Company, Limited Composition pharmaceutique utilisee pour inhiber la production des facteurs de necrose tumorale
JPH11209350A (ja) 1998-01-26 1999-08-03 Eisai Co Ltd 含窒素複素環誘導体およびその医薬
DE602004008762T2 (de) * 2003-04-30 2008-06-12 The Institutes for Pharmaceutical Discovery, LLC, Branford Substituierte heteroarylverbindungen als inhibitoren von proteintyrosinphosphatasen
MXPA06005019A (es) * 2003-11-03 2006-07-06 Warner Lambert Co Nuevos inhibidores de la recaptacion de norpinefrina para el tratamiento de transtornos del sistema nervioso central.
BRPI0614032A2 (pt) * 2005-06-27 2011-03-01 Hoffmann La Roche guanidinas substituìdas com cloro
US7855194B2 (en) 2006-03-27 2010-12-21 Hoffmann-La Roche Inc. Pyrimidine, quinazoline, pteridine and triazine derivatives
KR20140054433A (ko) 2006-11-22 2014-05-08 스미또모 가가꾸 가부시끼가이샤 사이토카이닌 신호전달을 저해할 수 있는 물질

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA894239A (en) * 1972-02-29 Pfizer Inc. Nitrogen heterocycles
US3305553A (en) * 1965-10-18 1967-02-21 Parke Davis & Co 2-aminoquinazoline derivatives
US3509141A (en) * 1966-09-15 1970-04-28 Ciba Geigy Corp 2-amino-quinazolines
GB1347493A (en) * 1971-02-11 1974-02-27 Aspro Nicholas Ltd Benzazine derivatives
JPS5398997A (en) * 1977-02-09 1978-08-29 Sumitomo Chem Co Ltd Fused pyridine derivertives and process for their preparation

Also Published As

Publication number Publication date
YU43528B (en) 1989-08-31
CA1236102A (en) 1988-05-03
ES8307226A1 (es) 1983-07-01
ZA827516B (en) 1983-08-31
NO823491L (no) 1983-04-22
FI73982B (fi) 1987-08-31
SU1299511A3 (ru) 1987-03-23
FI73982C (fi) 1987-12-10
FR2514765A1 (fr) 1983-04-22
DE3268699D1 (en) 1986-03-06
FR2514765B1 (da) 1984-04-06
PT75667A (fr) 1982-11-01
DK156063B (da) 1989-06-19
CS229692B2 (en) 1984-06-18
AU551938B2 (en) 1986-05-15
AU8962882A (en) 1983-04-28
DK156063C (da) 1989-11-13
KR880001077B1 (ko) 1988-06-22
ES516694A0 (es) 1983-07-01
HU187579B (en) 1986-01-28
EP0079810A1 (fr) 1983-05-25
FI823580A0 (fi) 1982-10-20
KR840001968A (ko) 1984-06-07
GR76535B (da) 1984-08-10
NO164167B (no) 1990-05-28
YU223382A (en) 1984-10-31
IE53653B1 (en) 1989-01-04
PT75667B (fr) 1985-01-11
EP0079810B1 (fr) 1986-01-22
JPS5888369A (ja) 1983-05-26
IL66960A0 (en) 1983-02-23
NZ202237A (en) 1985-08-30
FI823580L (fi) 1983-04-22
DD210040A5 (de) 1984-05-30
IE822447L (en) 1983-04-21
US4499092A (en) 1985-02-12
NO164167C (no) 1990-09-05
ATE17576T1 (de) 1986-02-15

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PBP Patent lapsed