DK485881A - Hexitoler indeholdende fri carboxylgruppe eller et salt deraf deres fremstilling og anvendelse som tumorhaemmende midler - Google Patents

Hexitoler indeholdende fri carboxylgruppe eller et salt deraf deres fremstilling og anvendelse som tumorhaemmende midler

Info

Publication number: DK485881A
Authority: DK; Denmark
Prior art keywords: carbon atoms; unsaturated; group; free carboxy; saturated
Prior art date: 1980-11-04

Application number

DK485881A

Other languages

English (en)

Inventor

I Elekes

L Institoris

K Medzihradszky

L Oetvoes

H Medzihradszky

K D Gleria

J Sugar

Z Somfai-Relle

S Eckhardt

I Hidy

S Kerpel-Fronius

Original Assignee

Chinoin Gyogyszer Es Vegyeszet

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-11-04

Filing date

1981-11-03

Publication date

1982-05-05

1981-11-03 Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet

1982-05-05 Publication of DK485881A publication Critical patent/DK485881A/da

Links

150000003839 salts Chemical class 0.000 title abstract 2
-1 CARBOXYL GROUP Chemical group 0.000 title 1
239000003112 inhibitor Substances 0.000 title 1
125000004432 carbon atom Chemical group C* 0.000 abstract 7
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 6
229920006395 saturated elastomer Polymers 0.000 abstract 6
125000004448 alkyl carbonyl group Chemical group 0.000 abstract 4
125000005099 aryl alkyl carbonyl group Chemical group 0.000 abstract 3
125000005129 aryl carbonyl group Chemical group 0.000 abstract 2
FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 abstract 1
FBPFZTCFMRRESA-ZXXMMSQZSA-N D-iditol Chemical compound OC[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-ZXXMMSQZSA-N 0.000 abstract 1
OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 1
229930195725 Mannitol Natural products 0.000 abstract 1
206010028980 Neoplasm Diseases 0.000 abstract 1
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
125000001584 benzyloxycarbonyl group Chemical group C(=O)(OCC1=CC=CC=C1)* 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
FBPFZTCFMRRESA-GUCUJZIJSA-N galactitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-GUCUJZIJSA-N 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
230000026030 halogenation Effects 0.000 abstract 1
238000005658 halogenation reaction Methods 0.000 abstract 1
FBPFZTCFMRRESA-UHFFFAOYSA-N hexane-1,2,3,4,5,6-hexol Chemical group OCC(O)C(O)C(O)C(O)CO FBPFZTCFMRRESA-UHFFFAOYSA-N 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
238000005984 hydrogenation reaction Methods 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
230000002401 inhibitory effect Effects 0.000 abstract 1
235000010355 mannitol Nutrition 0.000 abstract 1
239000000594 mannitol Substances 0.000 abstract 1
125000004430 oxygen atom Chemical group O* 0.000 abstract 1
UYWQUFXKFGHYNT-UHFFFAOYSA-N phenylmethyl ester of formic acid Natural products O=COCC1=CC=CC=C1 UYWQUFXKFGHYNT-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/16—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by esterified hydroxyl radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Hematology (AREA)
Oncology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Epoxy Compounds (AREA)
Peptides Or Proteins (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Separation By Low-Temperature Treatments (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Compounds Of Unknown Constitution (AREA)

DK485881A 1980-11-04 1981-11-03 Hexitoler indeholdende fri carboxylgruppe eller et salt deraf deres fremstilling og anvendelse som tumorhaemmende midler DK485881A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HU802649A HU182227B (en)	1980-11-04	1980-11-04	Process for preparing hexitols containing free carboxyl group

Publications (1)

Publication Number	Publication Date
DK485881A true DK485881A (da)	1982-05-05

Family

ID=10960444

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK485881A DK485881A (da)	1980-11-04	1981-11-03	Hexitoler indeholdende fri carboxylgruppe eller et salt deraf deres fremstilling og anvendelse som tumorhaemmende midler

Country Status (15)

Country	Link
US (1)	US4419522A (da)
EP (1)	EP0051467B1 (da)
JP (1)	JPH0699364B2 (da)
AT (1)	ATE21394T1 (da)
CA (1)	CA1192210A (da)
CS (1)	CS251066B2 (da)
DD (2)	DD202431A5 (da)
DE (1)	DE3175121D1 (da)
DK (1)	DK485881A (da)
FI (1)	FI66607C (da)
GR (1)	GR77292B (da)
HU (1)	HU182227B (da)
IL (1)	IL64088A0 (da)
SU (3)	SU1205769A3 (da)
YU (1)	YU259081A (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU195754B (en) *	1984-01-18	1988-07-28	Chinoin Gyogyszer Es Vegyeszet	Process for producing 1,2-5,6-dianhydro-3,4-diacyl-dulcitol
JP3046095B2 (ja) *	1991-05-23	2000-05-29	株式会社日立製作所	並列抵抗付遮断器
US8496917B2 (en) *	2009-11-13	2013-07-30	Sytheon Ltd	Compositions and methods for improving skin appearance
BR112013003671A2 (pt) *	2010-08-18	2017-01-10	Del Mar Pharmaceuticals	composições e métodos para melhorar os benefícios terapêuticos de compostos químicos administyrados sub-otimamente incluindo hexitóis substituídos tais como dianidrogalactitol e diacetildianidrogalactiol
EP3273951B1 (en)	2015-03-27	2020-07-29	Symbionyx Pharmaceuticals Inc.	Compositions and methods for treating psoriasis

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU172826B (hu) *	1974-12-24	1978-12-28	Mta Koezponti Kemiai Kutato In	Sposob poluchenija novykh acilnykh proizvodnykh 1,2-5,6-diangidro-geksitov s protivoopukholevoj aktivnost'ju

1980
- 1980-11-04 HU HU802649A patent/HU182227B/hu not_active IP Right Cessation
1981
- 1981-10-21 IL IL64088A patent/IL64088A0/xx not_active IP Right Cessation
- 1981-10-26 US US06/315,182 patent/US4419522A/en not_active Expired - Fee Related
- 1981-10-30 EP EP81305161A patent/EP0051467B1/en not_active Expired
- 1981-10-30 AT AT81305161T patent/ATE21394T1/de not_active IP Right Cessation
- 1981-10-30 DE DE8181305161T patent/DE3175121D1/de not_active Expired
- 1981-11-02 GR GR66405A patent/GR77292B/el unknown
- 1981-11-02 YU YU02590/81A patent/YU259081A/xx unknown
- 1981-11-02 JP JP56174703A patent/JPH0699364B2/ja not_active Expired - Lifetime
- 1981-11-02 FI FI813430A patent/FI66607C/fi not_active IP Right Cessation
- 1981-11-03 DK DK485881A patent/DK485881A/da not_active Application Discontinuation
- 1981-11-03 SU SU813350453A patent/SU1205769A3/ru active
- 1981-11-03 DD DD81234590A patent/DD202431A5/de not_active IP Right Cessation
- 1981-11-03 CS CS818075A patent/CS251066B2/cs unknown
- 1981-11-03 CA CA000389270A patent/CA1192210A/en not_active Expired
1982
- 1982-05-18 SU SU823437277A patent/SU1225487A3/ru active
- 1982-05-18 SU SU823437177A patent/SU1194863A1/ru active
1983
- 1983-11-03 DD DD83247073A patent/DD207374A5/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0051467B1 (en)	1986-08-13
YU259081A (en)	1983-12-31
DD202431A5 (de)	1983-09-14
GR77292B (da)	1984-09-11
CA1192210A (en)	1985-08-20
EP0051467A1 (en)	1982-05-12
FI813430L (fi)	1981-05-05
SU1205769A3 (ru)	1986-01-15
FI66607B (fi)	1984-07-31
IL64088A0 (en)	1982-01-31
DD207374A5 (de)	1984-02-29
SU1194863A1 (ru)	1985-11-30
HU182227B (en)	1983-12-28
DE3175121D1 (en)	1986-09-18
CS251066B2 (en)	1987-06-11
US4419522A (en)	1983-12-06
JPH0699364B2 (ja)	1994-12-07
FI66607C (fi)	1984-11-12
JPS57106642A (en)	1982-07-02
ATE21394T1 (de)	1986-08-15
SU1225487A3 (ru)	1986-04-15

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Legal Events

Date	Code	Title	Description
1993-10-04	AHS	Application shelved for other reasons than non-payment