DK496089A - Biologisk aktive phenylalkansyreforbindelser og fremgangsmaade til fremstilling deraf - Google Patents

Biologisk aktive phenylalkansyreforbindelser og fremgangsmaade til fremstilling deraf Download PDF

Info

Publication number: DK496089A
Authority: DK; Denmark
Prior art keywords: phenylalkanic; procedures; producing; biologically active; acid compounds
Prior art date: 1988-10-10

Application number

DK496089A

Other languages

English (en)

Other versions

DK496089D0 (da

Inventor

David Gwyn Cooper

Andrew Derrick Gribble

Original Assignee

Smith Kline French Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-10-10

Filing date

1989-10-06

Publication date

1990-04-11

1989-10-06 Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab

1989-10-06 Publication of DK496089D0 publication Critical patent/DK496089D0/da

1990-04-11 Publication of DK496089A publication Critical patent/DK496089A/da

Links

150000001875 compounds Chemical class 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
239000002253 acid Substances 0.000 title 1
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
125000002015 acyclic group Chemical group 0.000 abstract 1
150000001408 amides Chemical class 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
230000001404 mediated effect Effects 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1
RZWIIPASKMUIAC-VQTJNVASSA-N thromboxane Chemical compound CCCCCCCC[C@H]1OCCC[C@@H]1CCCCCCC RZWIIPASKMUIAC-VQTJNVASSA-N 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Diabetes (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

DK496089A 1988-10-10 1989-10-06 Biologisk aktive phenylalkansyreforbindelser og fremgangsmaade til fremstilling deraf DK496089A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB888823731A GB8823731D0 (en)	1988-10-10	1988-10-10	Biologically active compounds

Publications (2)

Publication Number	Publication Date
DK496089D0 DK496089D0 (da)	1989-10-06
DK496089A true DK496089A (da)	1990-04-11

Family

ID=10644962

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK496089A DK496089A (da)	1988-10-10	1989-10-06	Biologisk aktive phenylalkansyreforbindelser og fremgangsmaade til fremstilling deraf

Country Status (11)

Country	Link
EP (1)	EP0365183B1 (da)
JP (1)	JPH02157258A (da)
AT (1)	ATE85608T1 (da)
AU (1)	AU621667B2 (da)
DE (1)	DE68904863T2 (da)
DK (1)	DK496089A (da)
ES (1)	ES2054020T3 (da)
GB (1)	GB8823731D0 (da)
IE (1)	IE893246L (da)
PT (1)	PT91931B (da)
ZA (1)	ZA897660B (da)

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US6099856A (en)	1992-06-15	2000-08-08	Emisphere Technologies, Inc.	Active agent transport systems
US5693338A (en)	1994-09-29	1997-12-02	Emisphere Technologies, Inc.	Diketopiperazine-based delivery systems
US5578323A (en)	1992-06-15	1996-11-26	Emisphere Technologies, Inc.	Proteinoid carriers and methods for preparation and use thereof
US5447728A (en) *	1992-06-15	1995-09-05	Emisphere Technologies, Inc.	Desferrioxamine oral delivery system
US6331318B1 (en)	1994-09-30	2001-12-18	Emisphere Technologies Inc.	Carbon-substituted diketopiperazine delivery systems
US5443841A (en)	1992-06-15	1995-08-22	Emisphere Technologies, Inc.	Proteinoid microspheres and methods for preparation and use thereof
US5629020A (en)	1994-04-22	1997-05-13	Emisphere Technologies, Inc.	Modified amino acids for drug delivery
US6221367B1 (en)	1992-06-15	2001-04-24	Emisphere Technologies, Inc.	Active agent transport systems
US5451410A (en) *	1993-04-22	1995-09-19	Emisphere Technologies, Inc.	Modified amino acids for encapsulating active agents
US5714167A (en)	1992-06-15	1998-02-03	Emisphere Technologies, Inc.	Active agent transport systems
US5541155A (en)	1994-04-22	1996-07-30	Emisphere Technologies, Inc.	Acids and acid salts and their use in delivery systems
US5811127A (en)	1992-06-15	1998-09-22	Emisphere Technologies, Inc.	Desferrioxamine oral delivery system
US5792451A (en)	1994-03-02	1998-08-11	Emisphere Technologies, Inc.	Oral drug delivery compositions and methods
US5401516A (en)	1992-12-21	1995-03-28	Emisphere Technologies, Inc.	Modified hydrolyzed vegetable protein microspheres and methods for preparation and use thereof
ATE204467T1 (de)	1993-04-22	2001-09-15	Emisphere Tech Inc	Orale darreichungsform
US5643957A (en)	1993-04-22	1997-07-01	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US6610329B2 (en)	1993-04-22	2003-08-26	Emisphere Technologies Inc.	Compositions for the delivery of antigens
US5958457A (en)	1993-04-22	1999-09-28	Emisphere Technologies, Inc.	Compositions for the delivery of antigens
US5709861A (en)	1993-04-22	1998-01-20	Emisphere Technologies, Inc.	Compositions for the delivery of antigens
US6090958A (en)	1995-03-31	2000-07-18	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5965121A (en)	1995-03-31	1999-10-12	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
BR9604880A (pt)	1995-03-31	1998-05-19	Emisphere Tech Inc	Composto composição forma de unidade de dosagem métodos para administração de um agente biologicamente ativo para preparar uma composição para administração de um agente ativo e para preparar um composto e composição farmacológica
US5989539A (en)	1995-03-31	1999-11-23	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5866536A (en)	1995-03-31	1999-02-02	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5650386A (en)	1995-03-31	1997-07-22	Emisphere Technologies, Inc.	Compositions for oral delivery of active agents
US6001347A (en)	1995-03-31	1999-12-14	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5820881A (en)	1995-04-28	1998-10-13	Emisphere Technologies, Inc.	Microspheres of diamide-dicarboxylic acids
US5824345A (en)	1995-06-07	1998-10-20	Emisphere Technologies, Inc.	Fragrances and flavorants
US5750147A (en)	1995-06-07	1998-05-12	Emisphere Technologies, Inc.	Method of solubilizing and encapsulating itraconazole
US5667806A (en)	1995-06-07	1997-09-16	Emisphere Technologies, Inc.	Spray drying method and apparatus
US6051258A (en)	1995-06-07	2000-04-18	Emisphere Technologies, Inc.	Proteinoid emulsions and methods for preparation and use thereof
WO1997010197A1 (en)	1995-09-11	1997-03-20	Emisphere Technologies, Inc.	METHOD FOR PREPARING φ-AMINOALKANOIC ACID DERIVATIVES FROM CYCLOALKANONES
SI9720025A (sl)	1996-03-29	1999-08-31	Emishphere Technologies, Inc.	Spojine in sestavki za prenos aktivne snovi
CA2258264A1 (en)	1996-06-14	1997-12-18	Emisphere Technologies, Inc.	Microencapsulated fragrances and method for preparation
US6313088B1 (en)	1997-02-07	2001-11-06	Emisphere Technologies, Inc.	8-[(2-hydroxy-4-methoxy benzoyl) amino]-octanoic acid compositions for delivering active agents
US6060513A (en)	1997-02-07	2000-05-09	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5939381A (en)	1997-02-07	1999-08-17	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5876710A (en)	1997-02-07	1999-03-02	Emisphere Technologies Inc.	Compounds and compositions for delivering active agents
US5990166A (en)	1997-02-07	1999-11-23	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5879681A (en)	1997-02-07	1999-03-09	Emisphere Technolgies Inc.	Compounds and compositions for delivering active agents
US5804688A (en)	1997-02-07	1998-09-08	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US6358504B1 (en)	1997-02-07	2002-03-19	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5863944A (en)	1997-04-30	1999-01-26	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5962710A (en)	1997-05-09	1999-10-05	Emisphere Technologies, Inc.	Method of preparing salicyloylamino acids
BE1012386A3 (fr) *	1999-01-15	2000-10-03	Univ Liege	Derives de sulfonamides benzeniques et leurs utilisations.
EP1175390B1 (en)	1999-04-05	2005-02-02	Emisphere Technologies, Inc.	Disodium salts, monohydrates, and ethanol solvates
US7129274B1 (en)	1999-11-05	2006-10-31	Emisphere Technologies Inc.	Phenoxy carboxylic acid compounds and compositions for delivering active agents
US7279597B1 (en)	1999-11-05	2007-10-09	Emisphere Technologies, Inc.	Phenyl amine carboxylic acid compounds and compositions for delivering active agents
ES2298168T3 (es)	1999-12-16	2008-05-16	Emisphere Technologies, Inc.	Compuestos y composiciones para suministrar agentes activos.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3629320A (en) *	1969-04-09	1971-12-21	Geigy Chem Corp	2-(4-halo- and 4-trifluoromethylphenylsulfonamido)phenylacetic acids and esters thereof
DE3000377A1 (de) *	1980-01-07	1981-07-09	Boehringer Mannheim Gmbh, 6800 Mannheim	Neue sulfonamide, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
GB8600397D0 (en) *	1986-01-08	1986-02-12	Glaxo Group Ltd	Chemical compounds

1988
- 1988-10-10 GB GB888823731A patent/GB8823731D0/en active Pending
1989
- 1989-10-03 JP JP1258653A patent/JPH02157258A/ja active Pending
- 1989-10-05 AU AU42578/89A patent/AU621667B2/en not_active Ceased
- 1989-10-06 AT AT89310242T patent/ATE85608T1/de not_active IP Right Cessation
- 1989-10-06 DK DK496089A patent/DK496089A/da not_active Application Discontinuation
- 1989-10-06 DE DE8989310242T patent/DE68904863T2/de not_active Expired - Fee Related
- 1989-10-06 EP EP89310242A patent/EP0365183B1/en not_active Expired - Lifetime
- 1989-10-06 ES ES89310242T patent/ES2054020T3/es not_active Expired - Lifetime
- 1989-10-09 IE IE893246A patent/IE893246L/xx unknown
- 1989-10-09 ZA ZA897660A patent/ZA897660B/xx unknown
- 1989-10-09 PT PT91931A patent/PT91931B/pt not_active IP Right Cessation

Also Published As

Publication number	Publication date
PT91931A (pt)	1990-04-30
AU621667B2 (en)	1992-03-19
EP0365183A1 (en)	1990-04-25
JPH02157258A (ja)	1990-06-18
PT91931B (pt)	1995-05-31
ATE85608T1 (de)	1993-02-15
EP0365183B1 (en)	1993-02-10
DK496089D0 (da)	1989-10-06
ZA897660B (en)	1990-09-26
GB8823731D0 (en)	1988-11-16
DE68904863D1 (de)	1993-03-25
ES2054020T3 (es)	1994-08-01
AU4257889A (en)	1990-04-12
DE68904863T2 (de)	1993-06-24
IE893246L (en)	1990-04-10

Legal Events

Date	Code	Title	Description
1995-06-26	AHB	Application shelved due to non-payment

Publication	Publication Date	Title
DK496089D0 (da)	1989-10-06	Biologisk aktive phenylalkansyreforbindelser og fremgangsmaade til fremstilling deraf
DK602589A (da)	1990-05-31	Quinazolinonderivater
KR900700465A (ko)	1990-08-13	화합물
DK245888D0 (da)	1988-05-05	4-aminoquinolinderivater
DK363689A (da)	1990-01-26	Purinonderivater og fremgangsmaade til fremstilling deraf
ATE103812T1 (de)	1994-04-15	Zusammensetzung zur behandlung von ischaemischen stoerungen in organen.
FI895046A0 (fi)	1989-10-24	4-amino-3-acylkinolinderivat samt deras anvaendning saosom inhibitorer av sekretion av matsmaeltningsvaetskor.
ZA885241B (en)	1989-06-28	Biologically active compounds
ATE38982T1 (de)	1988-12-15	Guanidinmethylcyclohexancarbonsaeure-derivate, verfahren zur herstellung und pharmazeutische mittel.
WO1989001330A3 (en)	1989-05-05	W-arylsulphonamidoalkanoic acids for treatment of thromboxane mediated diseases
ATE88176T1 (de)	1993-04-15	2-hydroxy-3-aryloxy-propylaminderivate mit kardiovaskulaerer wirkung.
HUT47900A (en)	1989-04-28	Process for producing new amides of butenic acid and pharmaceutical compositions containing them as active components
PT87310A (pt)	1988-05-01	Process for the preparation of thiadiazole guanidines
ATE95697T1 (de)	1993-10-15	Uricosuretische zusammensetzung.
FI865302A0 (fi)	1986-12-23	Dioxanhexensyror.
FR2633292B1 (fr)	1990-11-09	Nouveaux derives de la 20,21-dinoreburnamenine substitues en 15 par un groupement amine, leur procede de preparation et les intermediaires ainsi obtenus, leur application comme medicaments et les compositions pharmaceutiques les reenfermant
ATE41770T1 (de)	1989-04-15	Derivate von n-(2-pyrrolidinylmethyl)benzamid, verfahren zu ihrer herstellung, zwischenprodukte und pharmazeutische zubereitung.