PT91931A - Processo de preparacao de derivados de acido fenilalcanoico e de composicoes farmaceuticas que os contem - Google Patents

Processo de preparacao de derivados de acido fenilalcanoico e de composicoes farmaceuticas que os contem

Info

Publication number: PT91931A
Authority: PT; Portugal
Prior art keywords: pharmaceutical compositions; compositions containing; phenylcanic; preparing; acid derivatives
Prior art date: 1988-10-10

Application number

PT91931A

Other languages

English (en)

Other versions

PT91931B (pt

Inventor

David Gwyn Cooper

Andrew Derrick Gribble

Original Assignee

Smith Kline French Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-10-10

Filing date

1989-10-09

Publication date

1990-04-30

1989-10-09 Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab

1990-04-30 Publication of PT91931A publication Critical patent/PT91931A/pt

1995-05-31 Publication of PT91931B publication Critical patent/PT91931B/pt

Links

238000000034 method Methods 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title abstract 2
239000002253 acid Substances 0.000 title 1
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
125000002015 acyclic group Chemical group 0.000 abstract 1
150000001408 amides Chemical class 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
230000001404 mediated effect Effects 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1
RZWIIPASKMUIAC-VQTJNVASSA-N thromboxane Chemical compound CCCCCCCC[C@H]1OCCC[C@@H]1CCCCCCC RZWIIPASKMUIAC-VQTJNVASSA-N 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/21—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Diabetes (AREA)
Hematology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

PT91931A 1988-10-10 1989-10-09 Processo de preparacao de derivados de acido fenilalcanoico e de composicoes farmaceuticas que os contem PT91931B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB888823731A GB8823731D0 (en)	1988-10-10	1988-10-10	Biologically active compounds

Publications (2)

Publication Number	Publication Date
PT91931A true PT91931A (pt)	1990-04-30
PT91931B PT91931B (pt)	1995-05-31

Family

ID=10644962

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT91931A PT91931B (pt)	1988-10-10	1989-10-09	Processo de preparacao de derivados de acido fenilalcanoico e de composicoes farmaceuticas que os contem

Country Status (11)

Country	Link
EP (1)	EP0365183B1 (pt)
JP (1)	JPH02157258A (pt)
AT (1)	ATE85608T1 (pt)
AU (1)	AU621667B2 (pt)
DE (1)	DE68904863T2 (pt)
DK (1)	DK496089A (pt)
ES (1)	ES2054020T3 (pt)
GB (1)	GB8823731D0 (pt)
IE (1)	IE893246L (pt)
PT (1)	PT91931B (pt)
ZA (1)	ZA897660B (pt)

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US5541155A (en)	1994-04-22	1996-07-30	Emisphere Technologies, Inc.	Acids and acid salts and their use in delivery systems
US5629020A (en) *	1994-04-22	1997-05-13	Emisphere Technologies, Inc.	Modified amino acids for drug delivery
US5714167A (en)	1992-06-15	1998-02-03	Emisphere Technologies, Inc.	Active agent transport systems
US5447728A (en) *	1992-06-15	1995-09-05	Emisphere Technologies, Inc.	Desferrioxamine oral delivery system
US6331318B1 (en)	1994-09-30	2001-12-18	Emisphere Technologies Inc.	Carbon-substituted diketopiperazine delivery systems
US6221367B1 (en)	1992-06-15	2001-04-24	Emisphere Technologies, Inc.	Active agent transport systems
US6099856A (en)	1992-06-15	2000-08-08	Emisphere Technologies, Inc.	Active agent transport systems
US5578323A (en)	1992-06-15	1996-11-26	Emisphere Technologies, Inc.	Proteinoid carriers and methods for preparation and use thereof
US5693338A (en)	1994-09-29	1997-12-02	Emisphere Technologies, Inc.	Diketopiperazine-based delivery systems
US5451410A (en) *	1993-04-22	1995-09-19	Emisphere Technologies, Inc.	Modified amino acids for encapsulating active agents
US5443841A (en)	1992-06-15	1995-08-22	Emisphere Technologies, Inc.	Proteinoid microspheres and methods for preparation and use thereof
US5811127A (en)	1992-06-15	1998-09-22	Emisphere Technologies, Inc.	Desferrioxamine oral delivery system
US5792451A (en)	1994-03-02	1998-08-11	Emisphere Technologies, Inc.	Oral drug delivery compositions and methods
US5401516A (en)	1992-12-21	1995-03-28	Emisphere Technologies, Inc.	Modified hydrolyzed vegetable protein microspheres and methods for preparation and use thereof
US5709861A (en)	1993-04-22	1998-01-20	Emisphere Technologies, Inc.	Compositions for the delivery of antigens
US5643957A (en)	1993-04-22	1997-07-01	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US6461643B2 (en)	1993-04-22	2002-10-08	Emisphere Technologies, Inc.	Oral drug delivery compositions and methods
US5958457A (en)	1993-04-22	1999-09-28	Emisphere Technologies, Inc.	Compositions for the delivery of antigens
IL109403A0 (en)	1993-04-22	1994-07-31	Emisphere Tech Inc	Oral drug delivery compositions and methods
US5866536A (en)	1995-03-31	1999-02-02	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5650386A (en)	1995-03-31	1997-07-22	Emisphere Technologies, Inc.	Compositions for oral delivery of active agents
CN1151836C (zh)	1995-03-31	2004-06-02	艾米斯菲尔技术有限公司	用作传送活性剂的化合物和组合物
US6001347A (en)	1995-03-31	1999-12-14	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US6090958A (en)	1995-03-31	2000-07-18	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5989539A (en)	1995-03-31	1999-11-23	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5965121A (en)	1995-03-31	1999-10-12	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5820881A (en)	1995-04-28	1998-10-13	Emisphere Technologies, Inc.	Microspheres of diamide-dicarboxylic acids
US5750147A (en)	1995-06-07	1998-05-12	Emisphere Technologies, Inc.	Method of solubilizing and encapsulating itraconazole
US5667806A (en)	1995-06-07	1997-09-16	Emisphere Technologies, Inc.	Spray drying method and apparatus
US5824345A (en)	1995-06-07	1998-10-20	Emisphere Technologies, Inc.	Fragrances and flavorants
US6051258A (en)	1995-06-07	2000-04-18	Emisphere Technologies, Inc.	Proteinoid emulsions and methods for preparation and use thereof
WO1997010197A1 (en)	1995-09-11	1997-03-20	Emisphere Technologies, Inc.	METHOD FOR PREPARING φ-AMINOALKANOIC ACID DERIVATIVES FROM CYCLOALKANONES
AU2595697A (en)	1996-03-29	1997-10-22	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
WO1997047288A1 (en)	1996-06-14	1997-12-18	Emisphere Technologies, Inc.	Microencapsulated fragrances and method for preparation
US5804688A (en)	1997-02-07	1998-09-08	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5879681A (en)	1997-02-07	1999-03-09	Emisphere Technolgies Inc.	Compounds and compositions for delivering active agents
US6313088B1 (en)	1997-02-07	2001-11-06	Emisphere Technologies, Inc.	8-[(2-hydroxy-4-methoxy benzoyl) amino]-octanoic acid compositions for delivering active agents
US6358504B1 (en)	1997-02-07	2002-03-19	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US6060513A (en)	1997-02-07	2000-05-09	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5939381A (en)	1997-02-07	1999-08-17	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5876710A (en)	1997-02-07	1999-03-02	Emisphere Technologies Inc.	Compounds and compositions for delivering active agents
US5990166A (en)	1997-02-07	1999-11-23	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5863944A (en)	1997-04-30	1999-01-26	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents
US5962710A (en)	1997-05-09	1999-10-05	Emisphere Technologies, Inc.	Method of preparing salicyloylamino acids
BE1012386A3 (fr) *	1999-01-15	2000-10-03	Univ Liege	Derives de sulfonamides benzeniques et leurs utilisations.
NZ534409A (en)	1999-04-05	2006-03-31	Emisphere Tech Inc	Disodium salts, monohydrates, and ethanol solvates for delivering active agents
US7129274B1 (en)	1999-11-05	2006-10-31	Emisphere Technologies Inc.	Phenoxy carboxylic acid compounds and compositions for delivering active agents
US7279597B1 (en)	1999-11-05	2007-10-09	Emisphere Technologies, Inc.	Phenyl amine carboxylic acid compounds and compositions for delivering active agents
EP1237872B1 (en)	1999-12-16	2008-02-27	Emisphere Technologies, Inc.	Compounds and compositions for delivering active agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3629320A (en) *	1969-04-09	1971-12-21	Geigy Chem Corp	2-(4-halo- and 4-trifluoromethylphenylsulfonamido)phenylacetic acids and esters thereof
DE3000377A1 (de) *	1980-01-07	1981-07-09	Boehringer Mannheim Gmbh, 6800 Mannheim	Neue sulfonamide, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
GB8600397D0 (en) *	1986-01-08	1986-02-12	Glaxo Group Ltd	Chemical compounds

1988
- 1988-10-10 GB GB888823731A patent/GB8823731D0/en active Pending
1989
- 1989-10-03 JP JP1258653A patent/JPH02157258A/ja active Pending
- 1989-10-05 AU AU42578/89A patent/AU621667B2/en not_active Ceased
- 1989-10-06 DK DK496089A patent/DK496089A/da not_active Application Discontinuation
- 1989-10-06 DE DE8989310242T patent/DE68904863T2/de not_active Expired - Fee Related
- 1989-10-06 ES ES89310242T patent/ES2054020T3/es not_active Expired - Lifetime
- 1989-10-06 AT AT89310242T patent/ATE85608T1/de not_active IP Right Cessation
- 1989-10-06 EP EP89310242A patent/EP0365183B1/en not_active Expired - Lifetime
- 1989-10-09 ZA ZA897660A patent/ZA897660B/xx unknown
- 1989-10-09 PT PT91931A patent/PT91931B/pt not_active IP Right Cessation
- 1989-10-09 IE IE893246A patent/IE893246L/xx unknown

Also Published As

Publication number	Publication date
ZA897660B (en)	1990-09-26
ES2054020T3 (es)	1994-08-01
DK496089D0 (da)	1989-10-06
PT91931B (pt)	1995-05-31
EP0365183A1 (en)	1990-04-25
DE68904863T2 (de)	1993-06-24
DE68904863D1 (de)	1993-03-25
EP0365183B1 (en)	1993-02-10
AU4257889A (en)	1990-04-12
ATE85608T1 (de)	1993-02-15
AU621667B2 (en)	1992-03-19
DK496089A (da)	1990-04-11
JPH02157258A (ja)	1990-06-18
GB8823731D0 (en)	1988-11-16
IE893246L (en)	1990-04-10

Legal Events

Date

Code

Title

Description

1995-05-31

FG3A

Patent granted, date of granting

Effective date: 19941118

1996-09-30

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19960531

Publication	Publication Date	Title
AU4257889A (en)	1990-04-12	Sulphonamido-phenylalkanoic acid derivatives having thromboxane A2 antagonist activity
PT91231A (pt)	1990-02-08	Processo de preparacao de derivados substituidos purinona e de composicoes farmaceuticas que os contem
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BR8704582A (pt)	1988-04-26	Processo para preparar derivados de piridinacarboxamida
MX11031A (es)	1993-11-01	Proceso para la preparacion de nuevas 1-fenil-3-naftaleniloxipropanaminas producto obtenido y composicion farmaceutica que lo incluye.
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PT96890A (pt)	1991-10-31	Processo para a preparacao de novos derivados com estrutura naftalenica e de composicoes farmaceuticas que os contem
PT89788A (pt)	1989-10-04	Processo de preparacao de derivados da quinolina substituidas e de composicoes farmaceuticas que os contem
AT384424B (de)	1987-11-10	Verfahren zur herstellung von neuen 3-hydroxy-2-oxo-pyrrolidinderivaten und ihren salzen
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PT94163A (pt)	1991-01-08	Processo para a preparacao de novas 2-aminotetralinas 8-substituidas e de composicoes farmaceuticas que as contem
PT96030A (pt)	1991-09-13	Processo para a preparacao de aminocarbonilcarbamatos relacionados com fisoestigmina e de composicoes farmaceuticas que os contem
DE3882438D1 (de)	1993-08-26	Alkansulfonanilid-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzung.
PT93450A (pt)	1990-11-07	Processo para a preparacao de novos derivados azetidinicos de acidos piridinocarboxilicos e de composicoes farmaceuticas que os contem
PT95651A (pt)	1991-09-13	Processo para a preparacao de derivados de benzo-ciclo-alquilamino-piridinaminas e de composicoes farmaceuticas que os contem
PT90635A (pt)	1989-11-30	Processo para a preparacao de derivados do acido n-(5,6,7,8-tetra-hidropirido-{2,3-d}pirimidin-6-il-alcanoil)glutamico
EP0446921A3 (en)	1992-01-29	Optically active alkylene-dioxybenzene derivatives and their use in therapy
PT92189A (pt)	1990-05-31	Processo para a preparacao de derivados de difenilacetamidas e de composicoes farmaceuticas que os contem
PT91051A (pt)	1990-02-08	Processo para a preparacao de novos derivados de glicerina e de composicoes farmaceuticas que os contem
PT82550B (pt)	1988-08-17	Processo de preparacao de derivados de 1,3-oxatiano e de composicoes farmaceuticas que os contem
PT98911A (pt)	1992-07-31	Processo para a preparacao de 3-(1h-indazol-3-il)-4-piridinaminas, seus intermediarios e composicoes farmaceuticas que os contem
ES2080062T3 (es)	1996-02-01	Derivados de carboximidamida.
PT92494A (pt)	1990-06-29	Processo para a preparacao de novos derivados do indol
PT84024B (pt)	1989-07-31	Processo para a preparacao de acidos dioxano-hexenoicos