DK513980A - Fremgangmaade til fremstilling af quinazolinderivater - Google Patents

Fremgangmaade til fremstilling af quinazolinderivater

Info

Publication number: DK513980A
Authority: DK; Denmark
Prior art keywords: carboxy; chem; alkyl; quinazoline derivatives; hydrogen
Prior art date: 1979-12-03

Application number

DK513980A

Other languages

English (en)

Inventor

I Ueda

M Kato

M Nagano

Original Assignee

Fujisawa Pharmaceutical Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-12-03

Filing date

1980-12-02

Publication date

1981-06-04

1980-12-02 Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co

1981-06-04 Publication of DK513980A publication Critical patent/DK513980A/da

Links

JWVCLYRUEFBMGU-UHFFFAOYSA-N quinazoline Chemical class N1=CN=CC2=CC=CC=C21 JWVCLYRUEFBMGU-UHFFFAOYSA-N 0.000 title 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 5
125000000217 alkyl group Chemical group 0.000 abstract 4
150000002431 hydrogen Chemical class 0.000 abstract 4
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
125000003545 alkoxy group Chemical group 0.000 abstract 3
125000004663 dialkyl amino group Chemical group 0.000 abstract 3
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
125000003302 alkenyloxy group Chemical group 0.000 abstract 2
125000002294 quinazolinyl group Chemical class N1=C(N=CC2=CC=CC=C12)* 0.000 abstract 2
125000004442 acylamino group Chemical group 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000004414 alkyl thio group Chemical group 0.000 abstract 1
239000000043 antiallergic agent Substances 0.000 abstract 1
125000004104 aryloxy group Chemical group 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
-1 nitro, amino Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
- C07D265/26—Two oxygen atoms, e.g. isatoic anhydride
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/94—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
- C07D239/96—Two oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Pulmonology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Immunology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK513980A 1979-12-03 1980-12-02 Fremgangmaade til fremstilling af quinazolinderivater DK513980A (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB7941607		1979-12-03
GB8031965		1980-10-03

Publications (1)

Publication Number	Publication Date
DK513980A true DK513980A (da)	1981-06-04

Family

ID=26273769

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK513980A DK513980A (da)	1979-12-03	1980-12-02	Fremgangmaade til fremstilling af quinazolinderivater

Country Status (10)

Country	Link
US (2)	US4377580A (da)
EP (1)	EP0030156B1 (da)
JP (1)	JPH0651686B2 (da)
AT (1)	ATE6778T1 (da)
AU (1)	AU541811B2 (da)
DE (1)	DE3067201D1 (da)
DK (1)	DK513980A (da)
ES (4)	ES497426A0 (da)
GR (1)	GR71637B (da)
IE (1)	IE51802B1 (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3046366A1 (de) *	1980-12-09	1982-07-08	Bayer Ag, 5090 Leverkusen	Tricyclische cytosinderivate zur verwendung in arzneimitteln und verfahren zu ihrer herstellung
JPS608274A (ja) *	1983-06-27	1985-01-17	Fujisawa Pharmaceut Co Ltd	新規キナゾリノン誘導体およびその製造法・並びに抗アレルギ−剤
NO162019C (no) *	1983-11-23	1989-10-25	Fujisawa Pharmaceutical Co	Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrimidoiskinolinderivater.
US5420133A (en) *	1993-03-19	1995-05-30	Merck & Co., Inc.	Quinazolinones substituted with phenoxyphenylacetic acid derivatives
CN101137412B (zh)	2005-01-13	2012-11-07	布里斯托尔-迈尔斯·斯奎布公司	用作凝血因子XIa抑制剂的取代的二芳基化合物
US9603848B2 (en) *	2007-06-08	2017-03-28	Senomyx, Inc.	Modulation of chemosensory receptors and ligands associated therewith
US7928111B2 (en) *	2007-06-08	2011-04-19	Senomyx, Inc.	Compounds including substituted thienopyrimidinone derivatives as ligands for modulating chemosensory receptors
US8633186B2 (en) *	2007-06-08	2014-01-21	Senomyx Inc.	Modulation of chemosensory receptors and ligands associated therewith
AU2013202912B2 (en) *	2007-06-08	2016-10-27	Firmenich Incorporated	Modulation of chemosensory receptors and ligands associated therewith
MX2011001155A (es)	2008-07-31	2011-07-29	Senomyx Inc	Composiciones que comprenden mejoradores del dulzor, y métodos para prepararlas.
EP3085699B1 (en)	2008-07-31	2022-03-02	Firmenich Incorporated	Processes for making sweet taste enhancers
CN103153096B (zh)	2010-08-12	2016-08-03	赛诺米克斯公司	提高甜味增强剂的稳定性的方法和包含稳定的甜味增强剂的组合物
JP6231085B2 (ja) *	2012-05-31	2017-11-15	エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト	アミノキナゾリン誘導体及びピリドピリミジン誘導体
AU2013299859B2 (en)	2012-08-06	2017-06-15	Firmenich Incorporated	Sweet flavor modifier
JO3155B1 (ar)	2013-02-19	2017-09-20	Senomyx Inc	معدِّل نكهة حلوة
WO2020033420A1 (en)	2018-08-07	2020-02-13	Firmenich Incorporated	5-substituted 4-amino-1h-benzo[c][1,2,6]thiadiazine 2,2-dioxides and formulations and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1086666A (en) *	1966-09-12	1967-10-11	Wander Ag Dr A	Novel 6-p-tolyl-2,3,6,7-tetrahydro-4h-pyrimido-[1,2-c] quinazoline
US3594379A (en) *	1968-09-16	1971-07-20	Sandoz Ag	2,3-dihydroimidazo(1,2-c)quinazolines
BE759842R (fr)	1969-12-05	1971-06-03	Sandoz Sa	Nouveaux derives de la 4-amino-quinazoline, leur preparation etmedicaments contenant ces
CA986932A (en) *	1970-08-27	1976-04-06	Shigeho Inaba	Process for preparing quinazoline derivatives
US4167569A (en) *	1976-12-09	1979-09-11	Imperial Chemical Industries Limited	Pyrimido[1,2-a ]benzimidazole derivatives
US4105766A (en) *	1977-08-19	1978-08-08	Sterling Drug Inc.	4,5-Dihydro-5-oxopyrazolo[1,5-a]quinazoline-3-carboxylic acid derivatives
US4192944A (en) *	1978-04-03	1980-03-11	Bristol-Myers Company	Optionally substituted 4-oxo-4H-pyrido[1,2-a]pyrimidine-3-N-(1H-tetrazol-4-yl)carboxamides and their use as antiallergy agents

1980
- 1980-11-21 IE IE2421/80A patent/IE51802B1/en unknown
- 1980-11-25 US US06/210,340 patent/US4377580A/en not_active Expired - Lifetime
- 1980-11-25 GR GR63451A patent/GR71637B/el unknown
- 1980-11-26 AU AU64733/80A patent/AU541811B2/en not_active Ceased
- 1980-12-02 EP EP80304335A patent/EP0030156B1/en not_active Expired
- 1980-12-02 DE DE8080304335T patent/DE3067201D1/de not_active Expired
- 1980-12-02 AT AT80304335T patent/ATE6778T1/de not_active IP Right Cessation
- 1980-12-02 DK DK513980A patent/DK513980A/da not_active Application Discontinuation
- 1980-12-03 ES ES497426A patent/ES497426A0/es active Granted
1981
- 1981-12-15 ES ES507996A patent/ES8207540A1/es not_active Expired
- 1981-12-15 ES ES507994A patent/ES8301234A1/es not_active Expired
- 1981-12-15 ES ES507995A patent/ES507995A0/es active Granted
1983
- 1983-01-03 US US06/455,411 patent/US4543356A/en not_active Expired - Fee Related
1991
- 1991-05-09 JP JP3201541A patent/JPH0651686B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
ATE6778T1 (de)	1984-04-15
ES507994A0 (es)	1982-11-16
EP0030156A1 (en)	1981-06-10
AU541811B2 (en)	1985-01-24
ES507996A0 (es)	1982-10-01
IE802421L (en)	1981-06-03
ES8207539A1 (es)	1982-10-01
US4377580A (en)	1983-03-22
US4543356A (en)	1985-09-24
AU6473380A (en)	1981-06-11
ES8205202A1 (es)	1982-06-01
IE51802B1 (en)	1987-04-01
ES8301234A1 (es)	1982-11-16
JPH0651686B2 (ja)	1994-07-06
ES8207540A1 (es)	1982-10-01
EP0030156B1 (en)	1984-03-21
JPH05294946A (ja)	1993-11-09
DE3067201D1 (en)	1984-04-26
ES507995A0 (es)	1982-10-01
GR71637B (da)	1983-06-20
ES497426A0 (es)	1982-06-01

Legal Events

Date	Code	Title	Description
1988-08-29	AHB	Application shelved due to non-payment

Publication	Publication Date	Title
AU541811B2 (en)	1985-01-24	Quinazoline derivatives
DK165244C (da)	1993-03-22	Analogifremgangsmaade til fremstilling af 1,2,3-trisubstituerede indoler
ES2070660B1 (es)	1996-01-01	Un procedimiento para la preparacion de 2,5-damino-3-hidroxihexanos sustituidos, utiles como inhibidores de proteasas retrovirales.
AU558433B2 (en)	1987-01-29	A fungicidal indanylbenzamide
ES8504130A1 (es)	1985-04-01	Un metodo para preparar derivados de 4-hidroxi-2-quinolona
ES545728A0 (es)	1987-08-01	Procedimiento para preparar 5h,11h-pirrolo (2,1c)-(1,4)ben- zoxazepinas sustituidas en posicion 11
ES2010284A6 (es)	1989-11-01	Procedimiento para preparar derivados de tiourea.
DK0589322T3 (da)	1997-09-22	5-Oxo-dibenzo a,d cyclohepta-1,4-diener samt deres anvendelse som retrovirale midler.
DK415789D0 (da)	1989-08-23	Tetracykliske antidepressive midler
ES8705421A1 (es)	1987-05-01	Un procedimiento para la preparacion de 4-amino-2-fenil-quinolinas
JPS53119866A (en)	1978-10-19	5-aryloxy-oxazoleakanoic acid derivatives and their preparation
NO853551L (no)	1986-03-13	Fremgangsmaate ved fremstilling av prolinderivater og lignende forbindelser med antihypertensiv aktivitet.
ES8301480A1 (es)	1982-12-01	Un procedimiento para la produccion de derivados de 11-piperazinil-5h--pirrolo 1,2-b, 1,2,5 benzotriazepina.
ES2035849T3 (es)	1993-05-01	Procedimiento para preparar derivados de eter difenilico.
ES2017493B3 (es)	1991-02-16	Herbicidas de difenil-eter.
ES515201A0 (es)	1983-11-01	"procedimiento para la fabricacion de derivados n- susbtituidos de la tetrahidroisftalimida".
ES548497A0 (es)	1986-03-16	Procedimiento para preparar compuestos de 3-amino-2,3-dihi- dro-1-benzoxepina
ES8302703A1 (es)	1983-02-01	"un procedimiento para la preparacion de fenil-quinolicidinas".
ES8606265A1 (es)	1986-04-16	Procedimiento para la preparacion de tiocarbamatos
ES8105713A1 (es)	1981-05-16	Un procedimiento para la preparacion de los enatiomeros levogiro y dextrogiro de la 1-ciclopropil-metil-4-(3-metoxi-5h- dibenzo (a,d) ciclohepten-5-iliden) piperidina