DK514989A - Enolestere og -ethere af 3-acyl-2-oxindol-1-carboxamider og deres anvendelse til fremstilling af laegemidler - Google Patents

Enolestere og -ethere af 3-acyl-2-oxindol-1-carboxamider og deres anvendelse til fremstilling af laegemidler

Info

Publication number: DK514989A
Authority: DK; Denmark
Prior art keywords: enolesters; oxindol; carboxamides; acyl; ethers
Prior art date: 1988-10-18

Application number

DK514989A

Other languages

English (en)

Other versions

DK514989D0 (da

Inventor

Thomas Charles Crawford

Lawrence Alan Reiter

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-10-18

Filing date

1989-10-17

Publication date

1990-04-19

1989-10-17 Application filed by Pfizer filed Critical Pfizer

1989-10-17 Publication of DK514989D0 publication Critical patent/DK514989D0/da

1990-04-19 Publication of DK514989A publication Critical patent/DK514989A/da

Links

150000002170 ethers Chemical class 0.000 title 1
229940126601 medicinal product Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Rheumatology (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pain & Pain Management (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DK514989A 1988-10-18 1989-10-17 Enolestere og -ethere af 3-acyl-2-oxindol-1-carboxamider og deres anvendelse til fremstilling af laegemidler DK514989A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/US1988/003658 WO1990004393A1 (en)	1988-10-18	1988-10-18	Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides

Publications (2)

Publication Number	Publication Date
DK514989D0 DK514989D0 (da)	1989-10-17
DK514989A true DK514989A (da)	1990-04-19

Family

ID=22208957

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK514989A DK514989A (da)	1988-10-18	1989-10-17	Enolestere og -ethere af 3-acyl-2-oxindol-1-carboxamider og deres anvendelse til fremstilling af laegemidler

Country Status (33)

Country	Link
US (1)	US5118703A (da)
JP (1)	JPH07597B2 (da)
KR (1)	KR910007237B1 (da)
CN (1)	CN1022241C (da)
AP (1)	AP118A (da)
AR (1)	AR246519A1 (da)
AT (1)	ATE125794T1 (da)
AU (1)	AU606819B2 (da)
BG (1)	BG50834A3 (da)
CA (1)	CA1339558C (da)
CZ (1)	CZ278983B6 (da)
DD (1)	DD285604A5 (da)
DK (1)	DK514989A (da)
EG (1)	EG19887A (da)
FI (1)	FI95253C (da)
HU (1)	HU208421B (da)
IE (1)	IE66586B1 (da)
IL (1)	IL91960A (da)
IS (1)	IS1598B (da)
MA (1)	MA21657A1 (da)
MX (1)	MX18021A (da)
MY (1)	MY104238A (da)
NO (1)	NO178027C (da)
NZ (1)	NZ231044A (da)
OA (1)	OA09140A (da)
PH (1)	PH27554A (da)
PL (2)	PL162316B1 (da)
PT (1)	PT92000B (da)
RO (1)	RO109195B1 (da)
RU (1)	RU2036905C1 (da)
SK (1)	SK278175B6 (da)
WO (1)	WO1990004393A1 (da)
YU (1)	YU48070B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5059693A (en) *	1989-10-06	1991-10-22	Pfizer Inc.	Process for making 3-aroyl-2-oxindole-1-carboxamides
RU2114854C1 (ru) *	1992-11-23	1998-07-10	Пфайзер Инк.	Производные 4-хлор-2-тиофенкарбоновой кислоты, способ получения 4-хлор-2-тиофенкарбоновой кислоты (варианты) и способ получения 5-фтор-6-хлор-3-(4-хлор-2-теноил)-2-оксиндол-1-карбоксамида (варианты)
US5270331A (en) *	1993-01-26	1993-12-14	Pfizer, Inc.	Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides
JP2709530B2 (ja) *	1993-02-09	1998-02-04	ファイザー・インク．	抗炎症薬としてのオキシンドール１−［ｎ−（アルコキシカルボニル）］カルボキサミド類および１−（ｎ−カルボキサミド）カルボキサミド類
US5449788A (en) *	1994-01-28	1995-09-12	Catalytica, Inc.	Process for preparing 2-oxindole-1-carboxamides
CN1094819C (zh) *	1997-04-30	2002-11-27	大兴株式会社	环状坯料之制造装置
EP0984012A3 (en) *	1998-08-31	2001-01-10	Pfizer Products Inc.	Nitric oxide releasing oxindole prodrugs with analgesic and anti-inflammatory properties
WO2001030151A1 (en) *	1999-10-26	2001-05-03	The University Of Texas Southwestern Medical Center	Methods of treating hair loss comprising administering indoline compound

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL96047C (da) *	1956-06-08
US3564009A (en) *	1966-01-13	1971-02-16	Sumitomo Chemical Co	Process for producing 1-acylindole derivatives
BE756447A (fr) *	1969-10-15	1971-03-22	Pfizer	Oxindolecarboxamides
US3923996A (en) *	1972-07-31	1975-12-02	Sandoz Ag	3-Substituted-oxindoles in compositions and methods of treating obesity
IE53102B1 (en) *	1981-05-12	1988-06-22	Ici Plc	Pharmaceutical spiro-succinimide derivatives
DE3268971D1 (en) *	1981-10-06	1986-03-20	Ici Plc	Biochemical process
US4556672A (en) *	1984-03-19	1985-12-03	Pfizer Inc.	3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
US4752609A (en) *	1985-06-20	1988-06-21	Pfizer Inc.	Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds
RO105052B1 (en) *	1987-02-02	1994-12-01	Pfizer	Producing process for the crystalline sodium salt, anhydre, of 5-chlorine-3-(2-tenoil)-2-oxindol-1-carboxamide
EP0365194B1 (en) *	1988-10-18	1995-08-02	Pfizer Inc.	Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides
US5047554A (en) *	1989-04-18	1991-09-10	Pfizer Inc.	3-substituted-2-oxindole derivatives
US5059693A (en) *	1989-10-06	1991-10-22	Pfizer Inc.	Process for making 3-aroyl-2-oxindole-1-carboxamides

1988
- 1988-10-18 MX MX1802188A patent/MX18021A/es unknown
- 1988-10-18 RO RO147347A patent/RO109195B1/ro unknown
- 1988-10-18 SK SK5906-89A patent/SK278175B6/sk unknown
- 1988-10-18 WO PCT/US1988/003658 patent/WO1990004393A1/en not_active Ceased
- 1988-10-18 US US07/675,883 patent/US5118703A/en not_active Expired - Lifetime
- 1988-10-18 HU HU886740A patent/HU208421B/hu not_active IP Right Cessation
1989
- 1989-09-20 IS IS3509A patent/IS1598B/is unknown
- 1989-09-28 CA CA000614317A patent/CA1339558C/en not_active Expired - Fee Related
- 1989-10-04 PH PH39329A patent/PH27554A/en unknown
- 1989-10-09 AT AT89310319T patent/ATE125794T1/de active
- 1989-10-12 IL IL9196089A patent/IL91960A/xx not_active IP Right Cessation
- 1989-10-16 PT PT92000A patent/PT92000B/pt not_active IP Right Cessation
- 1989-10-16 BG BG090022A patent/BG50834A3/xx unknown
- 1989-10-16 YU YU200589A patent/YU48070B/sh unknown
- 1989-10-16 AP APAP/P/1989/000141A patent/AP118A/en active
- 1989-10-16 MY MYPI89001415A patent/MY104238A/en unknown
- 1989-10-17 PL PL89281871A patent/PL162316B1/pl unknown
- 1989-10-17 MA MA21909A patent/MA21657A1/fr unknown
- 1989-10-17 CN CN89107943A patent/CN1022241C/zh not_active Expired - Fee Related
- 1989-10-17 DK DK514989A patent/DK514989A/da not_active Application Discontinuation
- 1989-10-17 AU AU42956/89A patent/AU606819B2/en not_active Ceased
- 1989-10-17 KR KR1019890014914A patent/KR910007237B1/ko not_active Expired
- 1989-10-17 OA OA59665A patent/OA09140A/xx unknown
- 1989-10-17 NZ NZ231044A patent/NZ231044A/en unknown
- 1989-10-17 IE IE333289A patent/IE66586B1/en not_active IP Right Cessation
- 1989-10-17 JP JP1270174A patent/JPH07597B2/ja not_active Expired - Lifetime
- 1989-10-17 DD DD89333653A patent/DD285604A5/de not_active IP Right Cessation
- 1989-10-17 AR AR89315179A patent/AR246519A1/es active
- 1989-10-17 PL PL89296831A patent/PL163112B1/pl unknown
- 1989-10-18 EG EG49689A patent/EG19887A/xx active
- 1989-10-18 CZ CS895906A patent/CZ278983B6/cs not_active IP Right Cessation
1991
- 1991-04-17 RU SU914895525A patent/RU2036905C1/ru active
- 1991-04-17 NO NO911512A patent/NO178027C/no unknown
- 1991-04-17 FI FI911855A patent/FI95253C/fi not_active IP Right Cessation

Also Published As

Publication number	Publication date
IL91960A (en)	1994-04-12
IS3509A7 (is)	1990-04-19
SK590689A3 (en)	1996-03-06
RU2036905C1 (ru)	1995-06-09
HUT58052A (en)	1992-01-28
PT92000A (pt)	1990-04-30
NO911512D0 (no)	1991-04-17
HU886740D0 (en)	1991-07-29
IL91960A0 (en)	1990-07-12
CZ590689A3 (en)	1994-04-13
ATE125794T1 (de)	1995-08-15
US5118703A (en)	1992-06-02
OA09140A (fr)	1991-10-31
CA1339558C (en)	1997-11-25
NO911512L (no)	1991-06-12
BG50834A3 (en)	1992-11-16
PL162316B1 (pl)	1993-09-30
NO178027B (no)	1995-10-02
DD285604A5 (de)	1990-12-19
PH27554A (en)	1993-08-18
IS1598B (is)	1996-05-20
FI911855A0 (fi)	1991-04-17
IE66586B1 (en)	1996-01-24
DK514989D0 (da)	1989-10-17
EG19887A (en)	1996-03-31
WO1990004393A1 (en)	1990-05-03
JPH07597B2 (ja)	1995-01-11
HU208421B (en)	1993-10-28
YU48070B (sh)	1997-01-08
AU606819B2 (en)	1991-02-14
AU4295689A (en)	1990-04-26
IE893332L (en)	1990-04-18
FI95253C (fi)	1996-01-10
MX18021A (es)	1993-11-01
NO178027C (no)	1996-01-10
KR910007237B1 (ko)	1991-09-24
SK278175B6 (en)	1996-03-06
AP8900141A0 (en)	1989-10-31
CZ278983B6 (en)	1994-11-16
CN1041938A (zh)	1990-05-09
NZ231044A (en)	1990-12-21
PT92000B (pt)	1995-06-30
MA21657A1 (fr)	1990-07-01
PL163112B1 (pl)	1994-02-28
CN1022241C (zh)	1993-09-29
RO109195B1 (ro)	1994-12-30
YU200589A (en)	1991-02-28
AP118A (en)	1991-02-22
AR246519A1 (es)	1994-08-31
KR900006285A (ko)	1990-05-07
MY104238A (en)	1994-02-28
FI95253B (fi)	1995-09-29
JPH02149559A (ja)	1990-06-08

Similar Documents

Publication	Publication Date	Title
DK165730C (da)	1993-06-07	Sammensaetning til afgivelse af hydrofobe medikamenter og dennes fremstilling
DK195587A (da)	1987-10-20	Phenylpiperazinderivater og deres anvendelse til fremstilling af antiarrytmi-laegemidler
DK51493A (da)	1993-05-05	Laegemiddel indeholdende humant interleukin-1alfa og anvendelse af interleukin-1alfa til fremstilling af et saadant laegemiddel
DK495585D0 (da)	1985-10-29	Farmaceutisk praeparat med kontrolleret frigivelse og fremgangsmaade til fremstilling af samme
DK118791D0 (da)	1991-06-19	1-benzopyran-4-oner og 2-amino-1,3-benzoxazin-4-oner, deres fremstilling og anvendelse som eller til fremstilling af laegemidler
DK189581A (da)	1981-11-15	Hidtil ukendte heparinestere der er anvendelige til fremstilling af laegemidler og fremgangsmaader til deres frmstilling
DK288785D0 (da)	1985-06-26	Benzensulfonamido-derivater til terapeutisk anvendelse og fremgangsmaade til fremstilling af saadanne derivater
DK546788D0 (da)	1988-09-30	Fremgangsmaade og anordning ti oparbejdning af flyveaske
DK535687D0 (da)	1987-10-13	Asbestfri friktionsmaterialer og fremgangsmaade til deres fremstilling
DK299089D0 (da)	1989-06-16	Anvendelse af prostaglandiner til fremstilling af laegemidler
DK537685A (da)	1986-05-23	Fremgangsmaade til fremstilling af isosilybinfrit silibinin samt laegemiddel med indhold deraf
DK408786D0 (da)	1986-08-27	Fremgangsmaade til fremstilling af vitaminforstadier og vitaminer
DK514989A (da)	1990-04-19	Enolestere og -ethere af 3-acyl-2-oxindol-1-carboxamider og deres anvendelse til fremstilling af laegemidler
DK154382A (da)	1982-10-08	Hidtil ukendte derivater af 2-piperazinopyrimidin,fremgangsmaader til deres fremstilling og deres anvendelse som laegemidlereller mellemprodukter til fremstilling af laegemidler
DK165985C (da)	1993-11-08	1-cytosinderivater, fremgangsmaader til deres fremstilling, samt anvendelse af dem i og til fremstilling af laegemidler
DK95489A (da)	1989-09-02	Anvendelse af quinolizin- og quinolizinonderivater til fremstilling af et laegemiddel
DK393489D0 (da)	1989-08-10	Benzodiazepinforbindelser og fremgangsmaade til deres fremstilling
DK221689A (da)	1989-11-07	Naturstensplade og fremgangsmaade til fremstilling af naturstensplade
DK701588D0 (da)	1988-12-16	N-hydroxy-5-phenyl-2-furancarboximidamider og anvendelse heraf til fremstilling af farmceutiske praeparater
DK13989A (da)	1989-07-16	Anvendelse af tnf og lt til fremstilling af laegemidler.
DK670588D0 (da)	1988-12-01	Farmaceutisk praeparat til behandling af phlebektasi og fremgangsmaade til fremstilling af praeparatet
DK170290A (da)	1990-07-16	Fremgangsmaade til fremstilling af vandoploeseligt primycin og dets komponent samt farmaceutiske praeparater indeholdende dem
DK171089D0 (da)	1989-04-10	Anvendelse af tetrazolderivater til fremstilling af laegemidler
DK68790D0 (da)	1990-03-16	Anvendelse af tripeptidet l-pyroglutamyl-l-histidylglycin til fremstilling af laegemidler
DK630089D0 (da)	1989-12-13	Anvendelse af aryloxyalkanoler og estere deraf til fremstilling af farmaceutika til behandling af retrovirusinfektioner

Legal Events

Date	Code	Title	Description
1999-07-19	AHB	Application shelved due to non-payment