DK515285A - Imidazoliumsalte med blodsukker-saenkende virkning og farmaceutiske midler indeholdende saadanne forbindelser - Google Patents

Imidazoliumsalte med blodsukker-saenkende virkning og farmaceutiske midler indeholdende saadanne forbindelser Download PDF

Info

Publication number
DK515285A
DK515285A DK515285A DK515285A DK515285A DK 515285 A DK515285 A DK 515285A DK 515285 A DK515285 A DK 515285A DK 515285 A DK515285 A DK 515285A DK 515285 A DK515285 A DK 515285A
Authority
DK
Denmark
Prior art keywords
compounds
blood sugar
pharmaceutical agents
agents containing
imidazolium salts
Prior art date
Application number
DK515285A
Other languages
English (en)
Other versions
DK515285D0 (da
DK164547B (da
DK164547C (da
Inventor
Samuel James Dominianni
Terence T T Yen
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK515285D0 publication Critical patent/DK515285D0/da
Publication of DK515285A publication Critical patent/DK515285A/da
Publication of DK164547B publication Critical patent/DK164547B/da
Application granted granted Critical
Publication of DK164547C publication Critical patent/DK164547C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/60—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK515285A 1984-11-13 1985-11-08 Imidazoliumsalte til brug ved saenkning af blodsukkerniveauet hos pattedyr og farmaceutiske praeparater indeholdende saadanne salte DK164547C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/670,776 US4609670A (en) 1984-11-13 1984-11-13 Imidazolium hypoglycemic agents
US67077684 1984-11-13

Publications (4)

Publication Number Publication Date
DK515285D0 DK515285D0 (da) 1985-11-08
DK515285A true DK515285A (da) 1986-05-14
DK164547B DK164547B (da) 1992-07-13
DK164547C DK164547C (da) 1992-11-30

Family

ID=24691822

Family Applications (1)

Application Number Title Priority Date Filing Date
DK515285A DK164547C (da) 1984-11-13 1985-11-08 Imidazoliumsalte til brug ved saenkning af blodsukkerniveauet hos pattedyr og farmaceutiske praeparater indeholdende saadanne salte

Country Status (21)

Country Link
US (1) US4609670A (da)
EP (1) EP0182533B1 (da)
JP (1) JPH0647576B2 (da)
KR (1) KR880001231B1 (da)
CN (1) CN1013444B (da)
AR (1) AR244671A1 (da)
AT (1) ATE46505T1 (da)
AU (1) AU574532B2 (da)
CA (1) CA1266673A (da)
DE (1) DE3573114D1 (da)
DK (1) DK164547C (da)
EG (1) EG17707A (da)
ES (1) ES8702370A1 (da)
GR (1) GR852707B (da)
HU (1) HU195490B (da)
IE (1) IE59093B1 (da)
NZ (1) NZ214088A (da)
PH (1) PH21656A (da)
PT (1) PT81439B (da)
SU (1) SU1424733A3 (da)
ZA (1) ZA858499B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1142778C (zh) * 1995-01-18 2004-03-24 奥尔顿有限公司 噻唑鎓化合物用于预防和逆转高级糖基化终产物形成的用途
US5656261A (en) * 1995-01-18 1997-08-12 The Picower Institute For Medical Research Preventing and reversing advanced glycosylation endproducts
FI119756B (fi) * 1995-01-18 2009-03-13 Alteon Inc Tiatsoliumyhdisteiden käyttö pitkälle edenneen glykosylaation lopputuotteiden muodostumisen estossa ja suunnan muutoksessa
US20040198795A1 (en) * 1996-05-08 2004-10-07 Wagle Dilip R Substituted imidazoliums and methods of use therefor
US6121300A (en) * 1998-11-10 2000-09-19 Wagle; Dilip R. Reversing advanced glycosylation cross-links using heterocyclic-substituted thiazolium salts
US6781039B2 (en) * 2002-05-07 2004-08-24 Stine Seed Farm, Inc. Soybean cultivar S010360
DE102006028264B4 (de) * 2006-01-10 2008-12-11 Uwe Pisching Sägebock
CN100460395C (zh) * 2006-07-06 2009-02-11 云南大学 芳环和杂环酰甲基咪唑盐类化合物及其制备方法
EP3064204A1 (en) * 2010-03-01 2016-09-07 GTx, Inc. Compounds for treatment of cancer
JP7692834B2 (ja) * 2019-03-11 2025-06-16 ノシオン セラピューティクス，インコーポレイテッド 荷電したイオンチャンネル遮断薬および使用方法
CA3129111A1 (en) 2019-03-11 2020-09-17 Bridget M. Cole Charged ion channel blockers and methods for use
US10933055B1 (en) 2019-11-06 2021-03-02 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3852301A (en) * 1973-06-21 1974-12-03 Squibb & Sons Inc Enol betaines of imidazoles
US4017631A (en) * 1974-11-19 1977-04-12 Janssen Pharmaceutica N.V. Imidazolium salts
GB1533706A (en) * 1976-03-01 1978-11-29 Ici Ltd Fungicidal imidazoles and 1,2,4-triazoles
DE2643563A1 (de) * 1976-09-28 1978-03-30 Bayer Ag Alpha-(4-biphenylyl)-benzyl-azolium- salze, verfahren zu ihrer herstellung sowie ihre verwendung zur bekaempfung von mikroorganismen
DE2714290A1 (de) * 1977-03-31 1978-10-05 Bayer Ag Fungizide mittel
JPS5479278A (en) * 1977-12-05 1979-06-25 Nippon Soda Co Ltd Imidazolium halide
JPS58150567A (ja) * 1982-03-03 1983-09-07 Kissei Pharmaceut Co Ltd 新規な１，３−二置換イミダゾ−ル誘導体およびその製造方法
US4581370A (en) * 1983-07-12 1986-04-08 Schering A.G. Antiarrhythmic imidazoliums

Also Published As

Publication number Publication date
PT81439A (en) 1985-12-01
HUT39164A (en) 1986-08-28
EG17707A (en) 1990-08-30
EP0182533B1 (en) 1989-09-20
GR852707B (da) 1986-03-10
SU1424733A3 (ru) 1988-09-15
PH21656A (en) 1988-01-13
JPS61122212A (ja) 1986-06-10
CA1266673A (en) 1990-03-13
KR860004029A (ko) 1986-06-16
US4609670A (en) 1986-09-02
ZA858499B (en) 1987-06-24
AU4973785A (en) 1986-05-22
AR244671A1 (es) 1993-11-30
NZ214088A (en) 1988-09-29
AU574532B2 (en) 1988-07-07
DE3573114D1 (en) 1989-10-26
DK515285D0 (da) 1985-11-08
PT81439B (pt) 1988-03-03
IE59093B1 (en) 1994-01-12
CN1013444B (zh) 1991-08-07
CN85108115A (zh) 1986-07-30
DK164547B (da) 1992-07-13
KR880001231B1 (ko) 1988-07-12
IE852822L (en) 1986-05-13
ES8702370A1 (es) 1987-01-01
DK164547C (da) 1992-11-30
EP0182533A2 (en) 1986-05-28
JPH0647576B2 (ja) 1994-06-22
ATE46505T1 (de) 1989-10-15
EP0182533A3 (en) 1987-06-03
ES548797A0 (es) 1987-01-01
HU195490B (en) 1988-05-30

Similar Documents

Publication Publication Date Title
DK150986A (da) Hydroxamater med lipoxygenase-inhiberende virkning og terapeutiske midler indeholdende saadanne forbindelser
DK269186D0 (da) Dipeptidforbindelser med farmaceutisk virkning og praeparater indeholdende disse
DK453684A (da) Pyridinderivater til medicinsk anvendelse og farmaceutiske praeparater indeholdende pyridinderivater
DK163923C (da) 2-phenyl-3-aminomethyl-imidazooe1,2-aaapyridinderivater og farmaceutisk praeparat indeholdende saadanne forbindelser
DK453584A (da) Pyridinderivater til medicinsk anvendelse og farmaceutiske praeparater indeholdende pyridinderivater
DK165693C (da) 2-(n-substitueret guanidino)-4-heteroarylthiazol-forbindelser og farmaceutiske praeparater indeholdende disse
DK162986C (da) 4-substituerede 2-amino-5-hydroxypyrimidin-forbindelser og farmaceutiske praeparater indeholdende disse
DK346486A (da) Aminosalicylsyrederivater og farmaceutiske midler
DK475684D0 (da) Phenothiazinderivater og farmaceutiske praeparater indeholdende phenothiazinderivaterne
DK497685D0 (da) Ketongruppeholdige oxindol-3-carboxamid-derivater og laegemiddel indeholdende saadanne derivater
DK515285A (da) Imidazoliumsalte med blodsukker-saenkende virkning og farmaceutiske midler indeholdende saadanne forbindelser
DK253585D0 (da) Heterocyclisk substituerede 1,4-dihydropyridin-derivater og farmaceutiske praeparater indeholdende disse derivater
DK21785A (da) Dihydropyridinforbindelser og farmaceutiske praeparater indeholdende disse
DK712388A (da) Heterocyclisk substituerede oxo- eller thiophthalazinyl-eddikesyre-forbindelser og farmaceutiske praeparater indeholdende disse
DK4487D0 (da) Heterocycliske forbindelser og farmaceutiske praeparater indeholdende disse
DK81185A (da) Carboxicam-enolester-forbindelser og farmaceutiske praeparater indeholdende disse
DK449188A (da) 2'-deoxy-5-fluoruridinderivater og farmaceutiske praeparater med indhold af saadanne forbindelser
DK415087A (da) Terapeutiske midler indeholdende benzhydrylthiomethanderivater
FI840659A7 (fi) Uusia heterosyklisiä yhdisteitä, niiden synteesi, niitä sisältäviä valmisteita ja niiden käyttö lääketieteessä
DK453785D0 (da) Laegemiddel med grf-virkning
DK156771C (da) Bis-dioxopiperazin-derivater med antitumor-aktivitet og laegemiddelformuleringer indeholdende saadanne forbindelser
DK285286A (da) Fungicide forbindelser og midler
DK343688D0 (da) Benzodipyranforbindelse og dens farmaceutiske anvendelse
DK151785D0 (da) 3-aminoalkylthio-1-phenylindolforbindelser og farmaceutiske praeparater
IT8523158A0 (it) Composti eterociclici dotati di attivita' terapeutica.

Legal Events

Date Code Title Description
PBP Patent lapsed