DK524283D0 - Fremgangsmade til fremstilling af nitrosoureaderivater - Google Patents

Fremgangsmade til fremstilling af nitrosoureaderivater

Info

Publication number: DK524283D0
Authority: DK; Denmark
Prior art keywords: nitrosoure; addes; procedure; preparation; alkyl
Prior art date: 1982-11-17

Application number

DK5242/83A

Other languages

English (en)

Other versions

DK524283A (da

DK169340B1 (da

Inventor

Gilbert Lavielle

Claude Cudennec

Original Assignee

Adir

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-11-17

Filing date

1983-11-16

Publication date

1983-11-16

1983-11-16 Application filed by Adir filed Critical Adir

1983-11-16 Publication of DK524283D0 publication Critical patent/DK524283D0/da

1984-05-18 Publication of DK524283A publication Critical patent/DK524283A/da

1994-10-10 Application granted granted Critical

1994-10-10 Publication of DK169340B1 publication Critical patent/DK169340B1/da

Links

125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 3
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
125000001424 substituent group Chemical group 0.000 abstract 2
206010028980 Neoplasm Diseases 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
OSTGTTZJOCZWJG-UHFFFAOYSA-N nitrosourea Chemical class NC(=O)N=NO OSTGTTZJOCZWJG-UHFFFAOYSA-N 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1
125000001544 thienyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

DK524283A 1982-11-17 1983-11-16 Analogifremgangsmåde til fremstilling af nitrosoureaderivater DK169340B1 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR8219199		1982-11-17
FR8219199A FR2536075B1 (fr)	1982-11-17	1982-11-17	Nouveaux derives de la nitrosouree, leur procede de preparation et les compositions pharmaceutiques les renfermant

Publications (3)

Publication Number	Publication Date
DK524283D0 true DK524283D0 (da)	1983-11-16
DK524283A DK524283A (da)	1984-05-18
DK169340B1 DK169340B1 (da)	1994-10-10

Family

ID=9279241

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK524283A DK169340B1 (da)	1982-11-17	1983-11-16	Analogifremgangsmåde til fremstilling af nitrosoureaderivater

Country Status (19)

Country	Link
US (1)	US4567169A (da)
EP (1)	EP0117959B1 (da)
JP (1)	JPS59106497A (da)
AT (1)	ATE21905T1 (da)
AU (1)	AU557139B2 (da)
CA (1)	CA1204442A (da)
DE (1)	DE3365900D1 (da)
DK (1)	DK169340B1 (da)
ES (1)	ES527353A0 (da)
FR (1)	FR2536075B1 (da)
IE (1)	IE56259B1 (da)
IL (1)	IL70253A (da)
MA (1)	MA19952A1 (da)
NO (1)	NO163409C (da)
NZ (1)	NZ206293A (da)
OA (1)	OA07589A (da)
PT (1)	PT77666B (da)
SU (1)	SU1303024A3 (da)
ZA (1)	ZA838558B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2567129B1 (fr) *	1984-07-06	1986-12-05	Adir	Nouveaux derives de l'oxaazaphosphorine, leur procede de preparation et les compositions pharmaceutiques les renfermant
IT1246778B (it) *	1991-04-12	1994-11-26	Boehringer Mannheim Italia	Nitrosocarbamoil derivati di acidi gem-difosfonici, un processo per la loro preparazione e composizioni farmaceutiche che li contengono
US5298499A (en) *	1991-07-05	1994-03-29	Research Triangle Institute	S-2-(substituted ethylamino)ethyl phosphorothioates
AU1057797A (en) *	1995-11-20	1997-06-11	Sepracor, Inc.	Antineoplastic methods and compositions employing optically pure (-)-fotemustine
CA2237909A1 (en) *	1995-11-20	1997-05-29	Nancy M. Gray	Antineoplastic methods and compositions employing (+)-fotemustine
US20040072889A1 (en) *	1997-04-21	2004-04-15	Pharmacia Corporation	Method of using a COX-2 inhibitor and an alkylating-type antineoplastic agent as a combination therapy in the treatment of neoplasia
CN100365002C (zh) *	2004-06-02	2008-01-30	上海医药科技发展有限公司	注射用福莫司汀制备工艺
AT501496B1 (de) *	2005-02-21	2007-03-15	Iep Gmbh	Verfahren zur enantioselektiven enzymatischen reduktion von ketoverbindungen
CN102311456A (zh) *	2011-07-08	2012-01-11	山东睿鹰先锋制药有限公司	一种福莫司汀原料药的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3920733A (en) *	1973-08-06	1975-11-18	Monsanto Co	Ureidoalkylphosphonic acids

1982
- 1982-11-17 FR FR8219199A patent/FR2536075B1/fr not_active Expired
1983
- 1983-11-02 US US06/547,881 patent/US4567169A/en not_active Expired - Lifetime
- 1983-11-15 PT PT77666A patent/PT77666B/pt unknown
- 1983-11-16 IL IL70253A patent/IL70253A/xx not_active IP Right Cessation
- 1983-11-16 EP EP83402209A patent/EP0117959B1/fr not_active Expired
- 1983-11-16 NO NO834214A patent/NO163409C/no unknown
- 1983-11-16 NZ NZ206293A patent/NZ206293A/en unknown
- 1983-11-16 AT AT83402209T patent/ATE21905T1/de active
- 1983-11-16 DK DK524283A patent/DK169340B1/da not_active IP Right Cessation
- 1983-11-16 DE DE8383402209T patent/DE3365900D1/de not_active Expired
- 1983-11-16 CA CA000441305A patent/CA1204442A/fr not_active Expired
- 1983-11-16 MA MA20173A patent/MA19952A1/fr unknown
- 1983-11-16 SU SU833665922A patent/SU1303024A3/ru active
- 1983-11-16 IE IE2680/83A patent/IE56259B1/en not_active IP Right Cessation
- 1983-11-16 AU AU21436/83A patent/AU557139B2/en not_active Expired
- 1983-11-16 ZA ZA838558A patent/ZA838558B/xx unknown
- 1983-11-17 OA OA58159A patent/OA07589A/xx unknown
- 1983-11-17 ES ES527353A patent/ES527353A0/es active Granted
- 1983-11-17 JP JP58217066A patent/JPS59106497A/ja active Granted

Also Published As

Publication number	Publication date
IL70253A0 (en)	1984-02-29
IE56259B1 (en)	1991-06-05
OA07589A (fr)	1985-03-31
US4567169A (en)	1986-01-28
FR2536075B1 (fr)	1985-07-05
JPS59106497A (ja)	1984-06-20
DK524283A (da)	1984-05-18
EP0117959A2 (fr)	1984-09-12
CA1204442A (fr)	1986-05-13
NO834214L (no)	1984-05-18
SU1303024A3 (ru)	1987-04-07
ES8501772A1 (es)	1984-12-01
PT77666B (fr)	1986-05-12
AU2143683A (en)	1984-05-24
DE3365900D1 (en)	1986-10-09
MA19952A1 (fr)	1984-07-01
NO163409B (no)	1990-02-12
JPS6411637B2 (da)	1989-02-27
EP0117959A3 (en)	1984-11-14
DK169340B1 (da)	1994-10-10
ES527353A0 (es)	1984-12-01
EP0117959B1 (fr)	1986-09-03
FR2536075A1 (fr)	1984-05-18
PT77666A (fr)	1983-12-01
NZ206293A (en)	1987-02-20
ZA838558B (en)	1984-07-25
IL70253A (en)	1986-10-31
NO163409C (no)	1990-05-23
IE832680L (en)	1984-05-17
AU557139B2 (en)	1986-12-04
ATE21905T1 (de)	1986-09-15

Legal Events

Date	Code	Title	Description
1994-10-10	B1	Patent granted (law 1993)
2003-12-01	PUP	Patent expired

Publication	Publication Date	Title
SE8700499D0 (sv)	1987-02-10	Novel pharmacologically active compounds
IT1179866B (it)	1987-09-16	Derivati del triptofano farmaceuticamente attivi e composizioni farmaceutiche che li contengono
ES525653A0 (es)	1984-06-01	Procedimiento para preparar nuevos diazabiciclo-(3.3.1)-nonanos
SE7704256L (sv)	1977-11-25	Nya substituerade fluoracylresorcin for lekemedel, kosmetika och pesticider samt forfarande for framstellning derav
DK524283A (da)	1984-05-18	Fremgangsmaade til fremstilling af nitrosoureaderivater
SE8802412L (sv)	1988-12-31	Tiokarbamidderivat
ES2032217T3 (es)	1993-01-16	Nuevos derivados n-(23-vinblastinoil del acido 1-amino-metilfosfonico, sus procedimientos de preparacion y las composiciones farmaceuticas que los contienen.
DK532679A (da)	1980-06-17	Fremgangsmaade til fremstilling af 2-aryl-3,4-diaza-bicyclo (4,1,0)hepten-(2)-on-(5).
SE8105689L (sv)	1982-03-27	Terapeutiska medel
ATE30152T1 (de)	1987-10-15	1-methyl-5-nitro-imidazolin-derivate und diese enthaltende therapeutische zusammensetzungen.
ATE18761T1 (de)	1986-04-15	Carbamoyloxybenzhydrol-derivate, ihre herstellung und ihre pharmazeutische zusammensetzungen.
NO872574D0 (no)	1987-06-19	Fremgangsmaate for fremstilling av terapeutisk aktive tetrahydro-benzotiazoler.
DE3269505D1 (en)	1986-04-03	Substituted 1-benzoyl-2-phenylimino-imidazolidines, their acid addition salts, process for their preparation and pharmaceutical compositions containing them
SE8400629D0 (sv)	1984-02-07	Novel basic oxime ethers and a process for preparing same
DK602083D0 (da)	1983-12-27	4-hydroxybenzhydroler
IT1175915B (it)	1987-08-12	Preparati farmaceutici ad azione analgesica contenenti 5 fenil-1, 4-benzodiazepine
FR2405965A1 (fr)	1979-05-11	Polyenes du type amide-acide et imide, leur preparation, les compositions durcissables et polymerisables les contenant, et leur utilisation pour le revetement