DK53083D0 - Fremgangsmade til fremstilling af 2-(phenyl-methylen)-cycloalkylaminer og-azetidiner eller syreadditionssalte deraf - Google Patents

Fremgangsmade til fremstilling af 2-(phenyl-methylen)-cycloalkylaminer og-azetidiner eller syreadditionssalte deraf

Info

Publication number
DK53083D0
DK53083D0 DK0530/83A DK53083A DK53083D0 DK 53083 D0 DK53083 D0 DK 53083D0 DK 0530/83 A DK0530/83 A DK 0530/83A DK 53083 A DK53083 A DK 53083A DK 53083 D0 DK53083 D0 DK 53083D0
Authority
DK
Denmark
Prior art keywords
cylamines
azetidines
cycloal
methylene
phenyl
Prior art date
Application number
DK0530/83A
Other languages
English (en)
Other versions
DK53083A (da
Inventor
Jacob Szmuskovicz
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of DK53083D0 publication Critical patent/DK53083D0/da
Publication of DK53083A publication Critical patent/DK53083A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
    • C07C45/66—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups by dehydration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/657—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings
    • C07C49/683—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings having unsaturation outside the aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK53083A 1982-02-09 1983-02-08 Fremgangsmaade til fremstilling af 2-(phenyl-methylen)-cycloalkylaminer og -azetidiner eller syreadditionssalte deraf DK53083A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34712382A 1982-02-09 1982-02-09
US06/408,333 US4540690A (en) 1982-02-09 1982-08-16 2-(Phenylmethylene)cycloalkylamines and -azetidines

Publications (2)

Publication Number Publication Date
DK53083D0 true DK53083D0 (da) 1983-02-08
DK53083A DK53083A (da) 1983-08-10

Family

ID=26995138

Family Applications (1)

Application Number Title Priority Date Filing Date
DK53083A DK53083A (da) 1982-02-09 1983-02-08 Fremgangsmaade til fremstilling af 2-(phenyl-methylen)-cycloalkylaminer og -azetidiner eller syreadditionssalte deraf

Country Status (11)

Country Link
US (1) US4540690A (da)
EP (1) EP0085811B1 (da)
AU (2) AU562051B2 (da)
DE (1) DE3271073D1 (da)
DK (1) DK53083A (da)
ES (6) ES519331A0 (da)
GR (1) GR78061B (da)
HU (1) HU190887B (da)
IL (1) IL67442A (da)
NZ (1) NZ202728A (da)
PH (1) PH17709A (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2634483B2 (fr) * 1987-12-29 1994-03-04 Esteve Labor Dr Derives des acides 7-(1-azetidinyl)-1,4-dihydro-4-oxoquinoleine-3-carboxyliques, leur preparation et leur application en tant que medicaments
JP3739377B2 (ja) * 2003-12-10 2006-01-25 シャープ株式会社 洗濯乾燥機
NZ548212A (en) * 2003-12-29 2010-07-30 Sepracor Inc Pyrrole and pyrazole DAAO inhibitors
WO2007006003A2 (en) 2005-07-06 2007-01-11 Sepracor Inc. Combinations of eszopiclone and trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-n-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine, and methods of treatment of menopause and mood, anxiety, and cognitive disorders
KR101294014B1 (ko) 2006-01-06 2013-08-09 선오비온 파마슈티컬스 인코포레이티드 모노아민 재흡수 저해제로서의 시클로알킬아민
US8053603B2 (en) * 2006-01-06 2011-11-08 Sunovion Pharmaceuticals Inc. Tetralone-based monoamine reuptake inhibitors
DK2816024T3 (da) 2006-03-31 2017-10-30 Sunovion Pharmaceuticals Inc Chirale aminer
US7579370B2 (en) * 2006-06-30 2009-08-25 Sepracor Inc. Fused heterocycles
US7884124B2 (en) 2006-06-30 2011-02-08 Sepracor Inc. Fluoro-substituted inhibitors of D-amino acid oxidase
US20080082066A1 (en) * 2006-10-02 2008-04-03 Weyerhaeuser Co. Crosslinked carboxyalkyl cellulose fibers having non-permanent and temporary crosslinks
US20090099248A1 (en) * 2007-01-18 2009-04-16 Sepracor Inc. Inhibitors of d-amino acid oxidase
US7902252B2 (en) * 2007-01-18 2011-03-08 Sepracor, Inc. Inhibitors of D-amino acid oxidase
MX2009012685A (es) * 2007-05-31 2009-12-14 Sepracor Inc Cicloalquilaminas sustituidas con fenilo como inhibidores de la reabsorcion de monoamina.
WO2010017418A1 (en) * 2008-08-07 2010-02-11 Sepracor Inc. Prodrugs of fused heterocyclic inhibitors of d-amino acid oxidase
WO2011017634A2 (en) * 2009-08-07 2011-02-10 Sepracore Inc. Prodrugs of fused heterocyclic inhibitors of d-amino acid oxidase
WO2013042139A1 (en) * 2011-09-23 2013-03-28 Advinus Therapeutics Limited Amide compounds, compositions and applications thereof
CA2953218A1 (en) 2014-06-06 2015-12-10 Allergan, Inc. Ep4 agonists as therapeutic compounds
KR102270026B1 (ko) * 2020-01-31 2021-06-28 현대약품 주식회사 (3s)-3-(4-(3-(1,4-다이옥사스파이로[4,5]데스-7-엔-8-일)벤질옥시)페닐)헥스-4-이노익산의 품질 평가 방법

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3595867A (en) * 1966-06-13 1971-07-27 Upjohn Co 2 - piperidino- and methyl-substituted piperidino-substituted-phentl cycloalkane-methanols and derivatives
US3668199A (en) * 1966-06-13 1972-06-06 Upjohn Co 1,3-aminoalcohols
US3705176A (en) * 1966-06-13 1972-12-05 Upjohn Co 1,3-aminoalcohols
US3558599A (en) * 1966-06-13 1971-01-26 Upjohn Co 1-(2-(alpha-alkoxybenzyl and substituted benzyl)cycloalkyl)heterocyclic amines
US3632813A (en) * 1966-06-13 1972-01-04 Upjohn Co Substituted phenyl 2-piperidinocycloalkyl ketones
US3468881A (en) * 1966-08-15 1969-09-23 Upjohn Co Allylic amines
US3458523A (en) * 1966-08-15 1969-07-29 Upjohn Co 2-(2 - furoyl)cycloalkanones,2 - furyl-2-(heterocyclicamino) cycloalkyl ketones,and d-(2 - furyl)-2-heterocyclicamino-cyclohexanemethanols
US3506670A (en) * 1966-09-26 1970-04-14 Upjohn Co 2-hetero-amino-alpha,alpha-diaryl-cycloalkone-methanols and esters thereof
US3499033A (en) * 1967-01-06 1970-03-03 Upjohn Co Ethers of alpha-phenyl-2-aminocycloalkanemethanols
US3651232A (en) * 1968-09-10 1972-03-21 Upjohn Co Compositions and methods for lowering blood sugar levels
US4145435A (en) * 1976-11-12 1979-03-20 The Upjohn Company 2-aminocycloaliphatic amide compounds
US4098904A (en) * 1976-11-12 1978-07-04 The Upjohn Company Analgesic n-(2-aminocycloaliphatic)benzamides
US4242261A (en) * 1979-07-19 1980-12-30 A. H. Robins Company, Inc. Production of methylene-cycloamines
US4260606A (en) * 1979-07-19 1981-04-07 A. H. Robins Company, Inc. 3-Methyleneazetidine derivatives

Also Published As

Publication number Publication date
IL67442A (en) 1986-01-31
IL67442A0 (en) 1983-05-15
ES8502969A1 (es) 1984-10-01
HU190887B (en) 1986-12-28
ES523065A0 (es) 1985-02-01
DK53083A (da) 1983-08-10
AU9134382A (en) 1983-08-18
ES8501745A1 (es) 1984-12-16
AU562051B2 (en) 1987-05-28
ES523067A0 (es) 1984-12-16
ES8507483A1 (es) 1985-09-16
DE3271073D1 (de) 1986-06-12
NZ202728A (en) 1985-12-13
AU6350486A (en) 1987-01-15
EP0085811B1 (en) 1986-05-07
ES8501744A1 (es) 1984-12-16
US4540690A (en) 1985-09-10
ES519331A0 (es) 1984-12-16
ES523066A0 (es) 1984-12-16
PH17709A (en) 1984-11-19
ES532058A0 (es) 1985-09-16
ES8502673A1 (es) 1985-02-01
EP0085811A1 (en) 1983-08-17
ES523064A0 (es) 1984-10-01
ES8501746A1 (es) 1984-12-16
GR78061B (da) 1984-09-26

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