ES523064A0 - Procedimiento para preparar azetidinas. - Google Patents

Procedimiento para preparar azetidinas.

Info

Publication number
ES523064A0
ES523064A0 ES523064A ES523064A ES523064A0 ES 523064 A0 ES523064 A0 ES 523064A0 ES 523064 A ES523064 A ES 523064A ES 523064 A ES523064 A ES 523064A ES 523064 A0 ES523064 A0 ES 523064A0
Authority
ES
Spain
Prior art keywords
azetidins
preparing
procedure
preparing azetidins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES523064A
Other languages
English (en)
Other versions
ES8502969A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of ES8502969A1 publication Critical patent/ES8502969A1/es
Publication of ES523064A0 publication Critical patent/ES523064A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
    • C07C45/66—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups by dehydration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/657—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings
    • C07C49/683—Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings having unsaturation outside the aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES523064A 1982-02-09 1983-06-07 Procedimiento para preparar azetidinas. Granted ES523064A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34712382A 1982-02-09 1982-02-09
US06/408,333 US4540690A (en) 1982-02-09 1982-08-16 2-(Phenylmethylene)cycloalkylamines and -azetidines

Publications (2)

Publication Number Publication Date
ES8502969A1 ES8502969A1 (es) 1984-10-01
ES523064A0 true ES523064A0 (es) 1984-10-01

Family

ID=26995138

Family Applications (6)

Application Number Title Priority Date Filing Date
ES519331A Granted ES519331A0 (es) 1982-02-09 1983-01-28 Procedimiento para preparar un compuesto de 2-(fenilmetilen) cicloalquilaminas y -azetidinas.
ES523067A Expired ES8501746A1 (es) 1982-02-09 1983-06-07 Procedimiento para preparar 1-(2-(fenilmetilen)ciclohexil) azetidinas.
ES523064A Granted ES523064A0 (es) 1982-02-09 1983-06-07 Procedimiento para preparar azetidinas.
ES523066A Granted ES523066A0 (es) 1982-02-09 1983-06-07 Procedimiento para preparar compuestos de azetidinas. desglose de la patente n 519.331.
ES523065A Expired ES8502673A1 (es) 1982-02-09 1983-06-07 Procedimiento para preparar compuestos de n-(2-(fenilmetilen)cicloalquil) aminas libres. desglose de la patente n 519.331.
ES532058A Granted ES532058A0 (es) 1982-02-09 1984-04-30 Procedimiento para preparar un compuesto de 2-(fenilmetilen) cicloalquilaminas y azetidinas

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES519331A Granted ES519331A0 (es) 1982-02-09 1983-01-28 Procedimiento para preparar un compuesto de 2-(fenilmetilen) cicloalquilaminas y -azetidinas.
ES523067A Expired ES8501746A1 (es) 1982-02-09 1983-06-07 Procedimiento para preparar 1-(2-(fenilmetilen)ciclohexil) azetidinas.

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES523066A Granted ES523066A0 (es) 1982-02-09 1983-06-07 Procedimiento para preparar compuestos de azetidinas. desglose de la patente n 519.331.
ES523065A Expired ES8502673A1 (es) 1982-02-09 1983-06-07 Procedimiento para preparar compuestos de n-(2-(fenilmetilen)cicloalquil) aminas libres. desglose de la patente n 519.331.
ES532058A Granted ES532058A0 (es) 1982-02-09 1984-04-30 Procedimiento para preparar un compuesto de 2-(fenilmetilen) cicloalquilaminas y azetidinas

Country Status (11)

Country Link
US (1) US4540690A (es)
EP (1) EP0085811B1 (es)
AU (2) AU562051B2 (es)
DE (1) DE3271073D1 (es)
DK (1) DK53083A (es)
ES (6) ES519331A0 (es)
GR (1) GR78061B (es)
HU (1) HU190887B (es)
IL (1) IL67442A (es)
NZ (1) NZ202728A (es)
PH (1) PH17709A (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2634483B2 (fr) * 1987-12-29 1994-03-04 Esteve Labor Dr Derives des acides 7-(1-azetidinyl)-1,4-dihydro-4-oxoquinoleine-3-carboxyliques, leur preparation et leur application en tant que medicaments
JP3739377B2 (ja) * 2003-12-10 2006-01-25 シャープ株式会社 洗濯乾燥機
NZ548212A (en) * 2003-12-29 2010-07-30 Sepracor Inc Pyrrole and pyrazole DAAO inhibitors
WO2007006003A2 (en) 2005-07-06 2007-01-11 Sepracor Inc. Combinations of eszopiclone and trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-n-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine, and methods of treatment of menopause and mood, anxiety, and cognitive disorders
KR101294014B1 (ko) 2006-01-06 2013-08-09 선오비온 파마슈티컬스 인코포레이티드 모노아민 재흡수 저해제로서의 시클로알킬아민
US8053603B2 (en) * 2006-01-06 2011-11-08 Sunovion Pharmaceuticals Inc. Tetralone-based monoamine reuptake inhibitors
DK2816024T3 (en) 2006-03-31 2017-10-30 Sunovion Pharmaceuticals Inc CHIRALE AMINER
US7579370B2 (en) * 2006-06-30 2009-08-25 Sepracor Inc. Fused heterocycles
US7884124B2 (en) 2006-06-30 2011-02-08 Sepracor Inc. Fluoro-substituted inhibitors of D-amino acid oxidase
US20080082066A1 (en) * 2006-10-02 2008-04-03 Weyerhaeuser Co. Crosslinked carboxyalkyl cellulose fibers having non-permanent and temporary crosslinks
US20090099248A1 (en) * 2007-01-18 2009-04-16 Sepracor Inc. Inhibitors of d-amino acid oxidase
US7902252B2 (en) * 2007-01-18 2011-03-08 Sepracor, Inc. Inhibitors of D-amino acid oxidase
MX2009012685A (es) * 2007-05-31 2009-12-14 Sepracor Inc Cicloalquilaminas sustituidas con fenilo como inhibidores de la reabsorcion de monoamina.
WO2010017418A1 (en) * 2008-08-07 2010-02-11 Sepracor Inc. Prodrugs of fused heterocyclic inhibitors of d-amino acid oxidase
WO2011017634A2 (en) * 2009-08-07 2011-02-10 Sepracore Inc. Prodrugs of fused heterocyclic inhibitors of d-amino acid oxidase
WO2013042139A1 (en) * 2011-09-23 2013-03-28 Advinus Therapeutics Limited Amide compounds, compositions and applications thereof
CA2953218A1 (en) 2014-06-06 2015-12-10 Allergan, Inc. Ep4 agonists as therapeutic compounds
KR102270026B1 (ko) * 2020-01-31 2021-06-28 현대약품 주식회사 (3s)-3-(4-(3-(1,4-다이옥사스파이로[4,5]데스-7-엔-8-일)벤질옥시)페닐)헥스-4-이노익산의 품질 평가 방법

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3595867A (en) * 1966-06-13 1971-07-27 Upjohn Co 2 - piperidino- and methyl-substituted piperidino-substituted-phentl cycloalkane-methanols and derivatives
US3668199A (en) * 1966-06-13 1972-06-06 Upjohn Co 1,3-aminoalcohols
US3705176A (en) * 1966-06-13 1972-12-05 Upjohn Co 1,3-aminoalcohols
US3558599A (en) * 1966-06-13 1971-01-26 Upjohn Co 1-(2-(alpha-alkoxybenzyl and substituted benzyl)cycloalkyl)heterocyclic amines
US3632813A (en) * 1966-06-13 1972-01-04 Upjohn Co Substituted phenyl 2-piperidinocycloalkyl ketones
US3468881A (en) * 1966-08-15 1969-09-23 Upjohn Co Allylic amines
US3458523A (en) * 1966-08-15 1969-07-29 Upjohn Co 2-(2 - furoyl)cycloalkanones,2 - furyl-2-(heterocyclicamino) cycloalkyl ketones,and d-(2 - furyl)-2-heterocyclicamino-cyclohexanemethanols
US3506670A (en) * 1966-09-26 1970-04-14 Upjohn Co 2-hetero-amino-alpha,alpha-diaryl-cycloalkone-methanols and esters thereof
US3499033A (en) * 1967-01-06 1970-03-03 Upjohn Co Ethers of alpha-phenyl-2-aminocycloalkanemethanols
US3651232A (en) * 1968-09-10 1972-03-21 Upjohn Co Compositions and methods for lowering blood sugar levels
US4145435A (en) * 1976-11-12 1979-03-20 The Upjohn Company 2-aminocycloaliphatic amide compounds
US4098904A (en) * 1976-11-12 1978-07-04 The Upjohn Company Analgesic n-(2-aminocycloaliphatic)benzamides
US4242261A (en) * 1979-07-19 1980-12-30 A. H. Robins Company, Inc. Production of methylene-cycloamines
US4260606A (en) * 1979-07-19 1981-04-07 A. H. Robins Company, Inc. 3-Methyleneazetidine derivatives

Also Published As

Publication number Publication date
IL67442A (en) 1986-01-31
IL67442A0 (en) 1983-05-15
ES8502969A1 (es) 1984-10-01
HU190887B (en) 1986-12-28
ES523065A0 (es) 1985-02-01
DK53083A (da) 1983-08-10
AU9134382A (en) 1983-08-18
ES8501745A1 (es) 1984-12-16
AU562051B2 (en) 1987-05-28
ES523067A0 (es) 1984-12-16
ES8507483A1 (es) 1985-09-16
DE3271073D1 (de) 1986-06-12
NZ202728A (en) 1985-12-13
AU6350486A (en) 1987-01-15
EP0085811B1 (en) 1986-05-07
ES8501744A1 (es) 1984-12-16
US4540690A (en) 1985-09-10
DK53083D0 (da) 1983-02-08
ES519331A0 (es) 1984-12-16
ES523066A0 (es) 1984-12-16
PH17709A (en) 1984-11-19
ES532058A0 (es) 1985-09-16
ES8502673A1 (es) 1985-02-01
EP0085811A1 (en) 1983-08-17
ES8501746A1 (es) 1984-12-16
GR78061B (es) 1984-09-26

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