ES523066A0 - Procedimiento para preparar compuestos de azetidinas. desglose de la patente n 519.331. - Google Patents

Procedimiento para preparar compuestos de azetidinas. desglose de la patente n 519.331.

Info

Publication number
ES523066A0
ES523066A0 ES523066A ES523066A ES523066A0 ES 523066 A0 ES523066 A0 ES 523066A0 ES 523066 A ES523066 A ES 523066A ES 523066 A ES523066 A ES 523066A ES 523066 A0 ES523066 A0 ES 523066A0
Authority
ES
Spain
Prior art keywords
breakdown
preparing
procedure
azetidin
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES523066A
Other languages
English (en)
Other versions
ES8501745A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of ES8501745A1 publication Critical patent/ES8501745A1/es
Publication of ES523066A0 publication Critical patent/ES523066A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
    • C07C45/66Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups by dehydration
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • C07C45/74Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups combined with dehydration
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/657Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings
    • C07C49/683Unsaturated compounds containing a keto groups being part of a ring containing six-membered aromatic rings having unsaturation outside the aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES523066A 1982-02-09 1983-06-07 Procedimiento para preparar compuestos de azetidinas. desglose de la patente n 519.331. Granted ES523066A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34712382A 1982-02-09 1982-02-09
US06/408,333 US4540690A (en) 1982-02-09 1982-08-16 2-(Phenylmethylene)cycloalkylamines and -azetidines

Publications (2)

Publication Number Publication Date
ES8501745A1 ES8501745A1 (es) 1984-12-16
ES523066A0 true ES523066A0 (es) 1984-12-16

Family

ID=26995138

Family Applications (6)

Application Number Title Priority Date Filing Date
ES519331A Expired ES8501744A1 (es) 1982-02-09 1983-01-28 Procedimiento para preparar un compuesto de 2-(fenilmetilen) cicloalquilaminas y -azetidinas.
ES523065A Expired ES8502673A1 (es) 1982-02-09 1983-06-07 Procedimiento para preparar compuestos de n-(2-(fenilmetilen)cicloalquil) aminas libres. desglose de la patente n 519.331.
ES523067A Expired ES8501746A1 (es) 1982-02-09 1983-06-07 Procedimiento para preparar 1-(2-(fenilmetilen)ciclohexil) azetidinas.
ES523064A Granted ES523064A0 (es) 1982-02-09 1983-06-07 Procedimiento para preparar azetidinas.
ES523066A Granted ES523066A0 (es) 1982-02-09 1983-06-07 Procedimiento para preparar compuestos de azetidinas. desglose de la patente n 519.331.
ES532058A Expired ES8507483A1 (es) 1982-02-09 1984-04-30 Procedimiento para preparar un compuesto de 2-(fenilmetilen) cicloalquilaminas y azetidinas

Family Applications Before (4)

Application Number Title Priority Date Filing Date
ES519331A Expired ES8501744A1 (es) 1982-02-09 1983-01-28 Procedimiento para preparar un compuesto de 2-(fenilmetilen) cicloalquilaminas y -azetidinas.
ES523065A Expired ES8502673A1 (es) 1982-02-09 1983-06-07 Procedimiento para preparar compuestos de n-(2-(fenilmetilen)cicloalquil) aminas libres. desglose de la patente n 519.331.
ES523067A Expired ES8501746A1 (es) 1982-02-09 1983-06-07 Procedimiento para preparar 1-(2-(fenilmetilen)ciclohexil) azetidinas.
ES523064A Granted ES523064A0 (es) 1982-02-09 1983-06-07 Procedimiento para preparar azetidinas.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES532058A Expired ES8507483A1 (es) 1982-02-09 1984-04-30 Procedimiento para preparar un compuesto de 2-(fenilmetilen) cicloalquilaminas y azetidinas

Country Status (11)

Country Link
US (1) US4540690A (es)
EP (1) EP0085811B1 (es)
AU (2) AU562051B2 (es)
DE (1) DE3271073D1 (es)
DK (1) DK53083A (es)
ES (6) ES8501744A1 (es)
GR (1) GR78061B (es)
HU (1) HU190887B (es)
IL (1) IL67442A (es)
NZ (1) NZ202728A (es)
PH (1) PH17709A (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2634483B2 (fr) * 1987-12-29 1994-03-04 Esteve Labor Dr Derives des acides 7-(1-azetidinyl)-1,4-dihydro-4-oxoquinoleine-3-carboxyliques, leur preparation et leur application en tant que medicaments
JP3739377B2 (ja) * 2003-12-10 2006-01-25 シャープ株式会社 洗濯乾燥機
CN1922149A (zh) * 2003-12-29 2007-02-28 塞普拉科公司 吡咯和吡唑daao抑制剂
CA2614282A1 (en) 2005-07-06 2007-01-11 Sepracor Inc. Combinations of eszopiclone and trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-n-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine, and methods of treatment of menopause and mood, anxiety, and cognitive disorders
EP1976513B1 (en) 2006-01-06 2016-08-24 Sunovion Pharmaceuticals Inc. Cycloalkylamines as monoamine reuptake inhibitors
KR101381768B1 (ko) * 2006-01-06 2014-04-07 선오비온 파마슈티컬스 인코포레이티드 테트랄론-기재 모노아민 재흡수 저해제
PT2816024T (pt) 2006-03-31 2017-10-20 Sunovion Pharmaceuticals Inc Aminas quirais
US7884124B2 (en) 2006-06-30 2011-02-08 Sepracor Inc. Fluoro-substituted inhibitors of D-amino acid oxidase
US7579370B2 (en) * 2006-06-30 2009-08-25 Sepracor Inc. Fused heterocycles
US20080082066A1 (en) * 2006-10-02 2008-04-03 Weyerhaeuser Co. Crosslinked carboxyalkyl cellulose fibers having non-permanent and temporary crosslinks
JP2010516697A (ja) * 2007-01-18 2010-05-20 セプラコール インク. D−アミノ酸オキシダーゼ阻害剤
US7902252B2 (en) * 2007-01-18 2011-03-08 Sepracor, Inc. Inhibitors of D-amino acid oxidase
WO2008151156A1 (en) 2007-05-31 2008-12-11 Sepracor Inc. Phenyl substituted cycloalkylamines as monoamine reuptake inhibitors
US20100120740A1 (en) * 2008-08-07 2010-05-13 Sepracor Inc. Prodrugs of fused heterocyclic inhibitors of d-amino acid oxidase
US20110034434A1 (en) * 2009-08-07 2011-02-10 Sepracor Inc. Prodrugs of fused heterocyclic inhibitors of d-amino acid oxidase
EP2758375A1 (en) * 2011-09-23 2014-07-30 Advinus Therapeutics Limited Amide compounds, compositions and applications thereof
ES2721525T3 (es) * 2014-06-06 2019-08-01 Allergan Inc Novedosos agonistas de EP4 como compuestos terapéuticos
KR102270026B1 (ko) * 2020-01-31 2021-06-28 현대약품 주식회사 (3s)-3-(4-(3-(1,4-다이옥사스파이로[4,5]데스-7-엔-8-일)벤질옥시)페닐)헥스-4-이노익산의 품질 평가 방법

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3632813A (en) * 1966-06-13 1972-01-04 Upjohn Co Substituted phenyl 2-piperidinocycloalkyl ketones
US3595867A (en) * 1966-06-13 1971-07-27 Upjohn Co 2 - piperidino- and methyl-substituted piperidino-substituted-phentl cycloalkane-methanols and derivatives
US3705176A (en) * 1966-06-13 1972-12-05 Upjohn Co 1,3-aminoalcohols
US3558599A (en) * 1966-06-13 1971-01-26 Upjohn Co 1-(2-(alpha-alkoxybenzyl and substituted benzyl)cycloalkyl)heterocyclic amines
US3668199A (en) * 1966-06-13 1972-06-06 Upjohn Co 1,3-aminoalcohols
US3468881A (en) * 1966-08-15 1969-09-23 Upjohn Co Allylic amines
US3458523A (en) * 1966-08-15 1969-07-29 Upjohn Co 2-(2 - furoyl)cycloalkanones,2 - furyl-2-(heterocyclicamino) cycloalkyl ketones,and d-(2 - furyl)-2-heterocyclicamino-cyclohexanemethanols
US3506670A (en) * 1966-09-26 1970-04-14 Upjohn Co 2-hetero-amino-alpha,alpha-diaryl-cycloalkone-methanols and esters thereof
US3499033A (en) * 1967-01-06 1970-03-03 Upjohn Co Ethers of alpha-phenyl-2-aminocycloalkanemethanols
US3651232A (en) * 1968-09-10 1972-03-21 Upjohn Co Compositions and methods for lowering blood sugar levels
US4145435A (en) * 1976-11-12 1979-03-20 The Upjohn Company 2-aminocycloaliphatic amide compounds
US4098904A (en) * 1976-11-12 1978-07-04 The Upjohn Company Analgesic n-(2-aminocycloaliphatic)benzamides
US4242261A (en) * 1979-07-19 1980-12-30 A. H. Robins Company, Inc. Production of methylene-cycloamines
US4260606A (en) * 1979-07-19 1981-04-07 A. H. Robins Company, Inc. 3-Methyleneazetidine derivatives

Also Published As

Publication number Publication date
PH17709A (en) 1984-11-19
ES532058A0 (es) 1985-09-16
AU9134382A (en) 1983-08-18
ES523065A0 (es) 1985-02-01
ES519331A0 (es) 1984-12-16
IL67442A0 (en) 1983-05-15
ES8502969A1 (es) 1984-10-01
EP0085811B1 (en) 1986-05-07
GR78061B (es) 1984-09-26
EP0085811A1 (en) 1983-08-17
ES523067A0 (es) 1984-12-16
ES8507483A1 (es) 1985-09-16
DK53083A (da) 1983-08-10
IL67442A (en) 1986-01-31
ES8501745A1 (es) 1984-12-16
ES523064A0 (es) 1984-10-01
HU190887B (en) 1986-12-28
ES8501744A1 (es) 1984-12-16
DK53083D0 (da) 1983-02-08
ES8501746A1 (es) 1984-12-16
AU6350486A (en) 1987-01-15
DE3271073D1 (de) 1986-06-12
US4540690A (en) 1985-09-10
ES8502673A1 (es) 1985-02-01
NZ202728A (en) 1985-12-13
AU562051B2 (en) 1987-05-28

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