DK538485A - Rekombinante dna-molekyler - Google Patents

Rekombinante dna-molekyler Download PDF

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Publication number
DK538485A
DK538485A DK538485A DK538485A DK538485A DK 538485 A DK538485 A DK 538485A DK 538485 A DK538485 A DK 538485A DK 538485 A DK538485 A DK 538485A DK 538485 A DK538485 A DK 538485A
Authority
DK
Denmark
Prior art keywords
recombinant dna
dna molecules
molecules
recombinant
dna
Prior art date
Application number
DK538485A
Other languages
Danish (da)
English (en)
Other versions
DK538485D0 (da
Inventor
A R Dunn
N M Gough
D Metcalf
Original Assignee
Research Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=3770545&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK538485(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Research Corp filed Critical Research Corp
Publication of DK538485D0 publication Critical patent/DK538485D0/da
Publication of DK538485A publication Critical patent/DK538485A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/53Colony-stimulating factor [CSF]
    • C07K14/535Granulocyte CSF; Granulocyte-macrophage CSF
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK538485A 1984-03-21 1985-11-21 Rekombinante dna-molekyler DK538485A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPG417384 1984-03-21
PCT/US1985/000465 WO1985004188A1 (en) 1984-03-21 1985-03-19 Recombinant dna molecules

Publications (2)

Publication Number Publication Date
DK538485D0 DK538485D0 (da) 1985-11-21
DK538485A true DK538485A (da) 1985-11-21

Family

ID=3770545

Family Applications (1)

Application Number Title Priority Date Filing Date
DK538485A DK538485A (da) 1984-03-21 1985-11-21 Rekombinante dna-molekyler

Country Status (8)

Country Link
US (1) US5602007A (de)
EP (2) EP0574029A1 (de)
JP (3) JPS61501490A (de)
AU (2) AU594014B2 (de)
DE (1) DE3587864T2 (de)
DK (1) DK538485A (de)
NL (1) NL940022I1 (de)
WO (1) WO1985004188A1 (de)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0041313B1 (de) 1980-04-03 1990-09-12 Biogen, Inc. DNS-Sequenzen, rekombinante DNS-Moleküle und Verfahren zur Herstellung von dem menschlichen Fibroblast-Interferon
UA39161C2 (uk) * 1984-07-06 2001-06-15 Новартіс Аг Рекомбінантний білок gm-csf для збільшення продукції гранулоцитів і макрофагів у пацієнтів, вектор і кднк, що його кодують
JPS61227526A (ja) * 1984-07-25 1986-10-09 Chugai Pharmaceut Co Ltd 新規なコロニー刺激因子
UA29377C2 (uk) * 1984-09-19 2000-11-15 Новартіс Аг Спосіб отримання білка з активністю колонієстимулювального фактора гранулоцитів та макрофагів(gm-csf) приматів
JP3038348B2 (ja) * 1984-11-20 2000-05-08 シェーリング コーポレイション ヒト顆粒状、マクロファージおよび好酸球の細胞増殖因子活性を示すポリペプチドをコードするcDNAクローン
US5078996A (en) * 1985-08-16 1992-01-07 Immunex Corporation Activation of macrophage tumoricidal activity by granulocyte-macrophage colony stimulating factor
DE3681551D1 (de) * 1985-09-30 1991-10-24 Chugai Pharmaceutical Co Ltd Menschlicher granulozyten-colony stimulierender faktor.
JPH0618778B2 (ja) * 1985-10-04 1994-03-16 中外製薬株式会社 白血球減少症治療剤
US5298603A (en) * 1985-12-21 1994-03-29 Hoechst Aktiengesellschaft GM-CSF protein, its derivatives, the preparation of proteins of this type, and their use
DE3545568A1 (de) * 1985-12-21 1987-07-16 Hoechst Ag Gm-csf-protein, seine derivate, herstellung solcher proteine und ihre verwendung
EP0232707A1 (de) * 1986-01-09 1987-08-19 Ajinomoto Co., Inc. Menschlicher Faktor zur Steigerung des hämatopoietischen Zellwachstums
US5106733A (en) * 1987-06-25 1992-04-21 Immunex Corporation Bovine granulocyte-macrophage colony stimulating factor
EP0413721A4 (en) * 1988-04-21 1991-11-13 Medvet Science Pty. Ltd. Human gm-csf variants
EP0486572B1 (de) * 1989-08-11 1998-01-07 Amrad Corporation Limited Rezeptor für granulozyten-macrophagen-koloniestimulierungsfaktor und seine derivate
DK0814154T3 (da) 1993-09-15 2009-08-31 Novartis Vaccines & Diagnostic Rekombinante alfavirusvektorer
EP0791061A4 (de) * 1994-03-04 1998-07-15 Ludwig Inst Cancer Res Tiere mit gezielter genunterbrechung
AU2800797A (en) 1996-04-05 1997-10-29 Chiron Corporation Recombinant alphavirus-based vectors with reduced inhibition of cellular macromolecular synthesis
EP2298900A1 (de) 1996-09-17 2011-03-23 Novartis Vaccines and Diagnostics, Inc. Zusammensetzungen und Verfahren zur Behandlung intrazellulärer Erkrankungen
US7153943B2 (en) * 1997-07-14 2006-12-26 Bolder Biotechnology, Inc. Derivatives of growth hormone and related proteins, and methods of use thereof
US6753165B1 (en) * 1999-01-14 2004-06-22 Bolder Biotechnology, Inc. Methods for making proteins containing free cysteine residues
US20080076706A1 (en) 1997-07-14 2008-03-27 Bolder Biotechnology, Inc. Derivatives of Growth Hormone and Related Proteins, and Methods of Use Thereof
ES2297889T3 (es) * 1997-07-14 2008-05-01 Bolder Biotechnology, Inc. Derivados de hormona de crecimiento y proteinas relacionadas.
US7507705B2 (en) 1997-10-02 2009-03-24 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Methods for the modulation of neovascularization and/or the growth of collateral arteries and/or other arteries from preexisting arteriolar connections
AU2221600A (en) 1998-12-31 2000-07-31 Chiron Corporation Improved expression of hiv polypeptides and production of virus-like particles
US7935805B1 (en) 1998-12-31 2011-05-03 Novartis Vaccines & Diagnostics, Inc Polynucleotides encoding antigenic HIV Type C polypeptides, polypeptides and uses thereof
US8288126B2 (en) 1999-01-14 2012-10-16 Bolder Biotechnology, Inc. Methods for making proteins containing free cysteine residues
ATE446767T1 (de) * 1999-02-12 2009-11-15 Univ Washington Gm-csf zur behandlung von morbus crohn
US6911204B2 (en) 2000-08-11 2005-06-28 Favrille, Inc. Method and composition for altering a B cell mediated pathology
HK1052314A1 (zh) * 2000-08-11 2003-09-11 Favrille, Inc. 改变t细胞介导的病理的方法和组合物
EP2280074A3 (de) 2001-07-05 2011-06-22 Novartis Vaccines and Diagnostics, Inc. Antigene typ-b- und/oder typ-c-hiv-polypeptide codierende polynukleotide, polypeptide und deren verwendungen
EP1411770A4 (de) 2001-07-05 2006-05-10 Chiron Corp Polynukleotide, die für antigene hiv-polypeptide des c-typs codieren, polypeptide und ihre verwendung
JP2006500905A (ja) 2002-02-13 2006-01-12 ルードヴィッヒ インスティテュート フォー キャンサー リサーチ ヒト化gm−csf抗体
EP2339010B1 (de) 2002-05-01 2017-04-12 Miltenyi Biotec Technology, Inc. Gegenüber Komplement-Inaktivierung resistente Lentivirusvektorpartikel
GB0210741D0 (en) * 2002-05-10 2002-06-19 Medical Res Council Methods of therapy
GB0224415D0 (en) * 2002-10-21 2002-11-27 Medical Res Council Compositions
US8541003B2 (en) 2003-06-20 2013-09-24 Protein Sciences Corporation Vectors expressing SARS immunogens, compositions containing such vectors or expression products thereof, methods and assays for making and using
CN101072585A (zh) 2004-11-01 2007-11-14 诺华疫苗和诊断公司 产生免疫应答的组合方法
GB0524103D0 (en) * 2005-11-26 2006-01-04 Medical Res Council Healing
US7741450B2 (en) 2006-02-08 2010-06-22 Morphotek Inc. Antibodies to GM-CSF
WO2007137300A2 (en) 2006-05-23 2007-11-29 Bellicum Pharmaceuticals, Inc. Modified dendritic cells having enhanced survival and immunogenicity and related compositions and methods
CA2777400C (en) 2009-10-12 2018-11-27 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Granulysin in immunotherapy
WO2012093258A2 (en) 2011-01-05 2012-07-12 Imperial Innovations Limited Treatment and screening
EP2870238A4 (de) 2012-07-05 2016-03-09 Ohio State Innovation Foundation Zusammensetzungen und verfahren in zusammenhang mit viralen impfstoffen
CA2996762A1 (en) 2015-08-31 2017-03-09 Technovax, Inc. Human respiratory syncytial virus (hrsv) virus-like particles (vlps) based vaccine
US10612005B2 (en) 2016-01-08 2020-04-07 Replimune Limited Modified oncolytic virus
JP7250520B2 (ja) 2016-04-13 2023-04-03 ヤンセン ファーマシューティカルズ,インコーポレーテッド 組換えアルテリウイルスレプリコン系およびその使用
KR102718353B1 (ko) 2016-10-17 2024-10-15 얀센 파마슈티칼즈, 인코포레이티드 재조합 바이러스 레플리콘 시스템 및 그의 용도
CA3045650A1 (en) 2016-12-05 2018-06-14 Janssen Pharmaceuticals, Inc. Compositions and methods for enhancing gene expression
GB201700350D0 (en) 2017-01-09 2017-02-22 Replimune Ltd Altered virus
EA202091517A1 (ru) 2017-12-19 2020-11-03 Янссен Сайенсиз Айрлэнд Анлимитед Компани Способы и устройство для доставки вакцин против вируса гепатита b (hbv)
EA202091516A1 (ru) 2017-12-19 2020-11-03 Янссен Сайенсиз Айрлэнд Анлимитед Компани Способы и композиции для индукции иммунного ответа против вируса гепатита b (hbv)
US11021692B2 (en) 2017-12-19 2021-06-01 Janssen Sciences Ireland Unlimited Company Hepatitis B virus (HBV) vaccines and uses thereof
JP7494117B2 (ja) 2018-01-19 2024-06-03 ヤンセン ファーマシューティカルズ,インコーポレーテッド 組換えレプリコン系を使用する免疫応答の誘導および増強
WO2020076775A1 (en) 2018-10-08 2020-04-16 Janssen Pharmaceuticals, Inc. Alphavirus-based replicons for administration of biotherapeutics

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN150740B (de) * 1978-11-24 1982-12-04 Hoffmann La Roche
US4438032A (en) * 1981-01-30 1984-03-20 The Regents Of The University Of California Unique T-lymphocyte line and products derived therefrom
US4658018A (en) * 1984-03-13 1987-04-14 Immunex Corporation Process for producing homogeneous colony stimulating factor
UA39161C2 (uk) * 1984-07-06 2001-06-15 Новартіс Аг Рекомбінантний білок gm-csf для збільшення продукції гранулоцитів і макрофагів у пацієнтів, вектор і кднк, що його кодують
JP3038348B2 (ja) * 1984-11-20 2000-05-08 シェーリング コーポレイション ヒト顆粒状、マクロファージおよび好酸球の細胞増殖因子活性を示すポリペプチドをコードするcDNAクローン
US4810643A (en) * 1985-08-23 1989-03-07 Kirin- Amgen Inc. Production of pluripotent granulocyte colony-stimulating factor
US5298603A (en) * 1985-12-21 1994-03-29 Hoechst Aktiengesellschaft GM-CSF protein, its derivatives, the preparation of proteins of this type, and their use

Also Published As

Publication number Publication date
US5602007A (en) 1997-02-11
DK538485D0 (da) 1985-11-21
EP0177568A1 (de) 1986-04-16
DE3587864D1 (de) 1994-07-28
EP0177568B1 (de) 1994-06-22
JPH10165190A (ja) 1998-06-23
DE3587864T2 (de) 1994-09-29
NL940022I1 (nl) 1995-01-02
AU629938B2 (en) 1992-10-15
WO1985004188A1 (en) 1985-09-26
EP0177568A4 (de) 1987-10-08
AU594014B2 (en) 1990-03-01
JPS61501490A (ja) 1986-07-24
EP0574029A1 (de) 1993-12-15
JPH09271A (ja) 1997-01-07
AU5589390A (en) 1990-09-13
AU4008485A (en) 1985-09-26

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