DK593986A - Forbindelser og farmaceutiske praeparater til inhibering af 5-lipoxygenase-vejen - Google Patents

Forbindelser og farmaceutiske praeparater til inhibering af 5-lipoxygenase-vejen

Info

Publication number: DK593986A
Authority: DK; Denmark
Prior art keywords: lipoxygenase; inhibiting; road; compounds; pharmaceutical preparations
Prior art date: 1985-12-12

Application number

DK593986A

Other languages

English (en)

Other versions

DK593986D0 (da

Inventor

Poul Elliot Bender

David Taylor Hill

Original Assignee

Smithkline Beckman Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-12-12

Filing date

1986-12-10

Publication date

1987-06-13

1986-12-10 Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp

1986-12-10 Publication of DK593986D0 publication Critical patent/DK593986D0/da

1987-06-13 Publication of DK593986A publication Critical patent/DK593986A/da

Links

102000001381 Arachidonate 5-Lipoxygenase Human genes 0.000 title 1
108010093579 Arachidonate 5-lipoxygenase Proteins 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1
230000002401 inhibitory effect Effects 0.000 title 1
239000000825 pharmaceutical preparation Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DK593986A 1985-12-12 1986-12-10 Forbindelser og farmaceutiske praeparater til inhibering af 5-lipoxygenase-vejen DK593986A (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US80839685A	1985-12-12	1985-12-12
US06/856,735 US4728656A (en)	1985-12-12	1986-04-28	2,2-alkyldiylbis(thio)bis(imidazoles) useful for inhibition of the 5-lipoxygenase pathway

Publications (2)

Publication Number	Publication Date
DK593986D0 DK593986D0 (da)	1986-12-10
DK593986A true DK593986A (da)	1987-06-13

Family

ID=27123120

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK593986A DK593986A (da)	1985-12-12	1986-12-10	Forbindelser og farmaceutiske praeparater til inhibering af 5-lipoxygenase-vejen

Country Status (9)

Country	Link
US (1)	US4728656A (da)
EP (1)	EP0229496B1 (da)
JP (1)	JPH072737B2 (da)
AU (1)	AU586056B2 (da)
DE (1)	DE3672254D1 (da)
DK (1)	DK593986A (da)
ES (1)	ES2016263B3 (da)
GR (1)	GR3000784T3 (da)
PT (1)	PT83903B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4847270A (en) *	1985-12-12	1989-07-11	Smithkline Beckman Corporation	Inhibition of the 5-lipoxygenase pathway utilizing certain 2,2'-alkyldiyl bis(thio)bis-imidazoles and derivatives
US5021440A (en) *	1989-07-31	1991-06-04	Merck & Co., Inc.	Imidazole compounds and their use as transglutaminase inhibitors
US5030644A (en) *	1989-07-31	1991-07-09	Merck & Co., Inc.	Imidazole compounds and their use as transglutaminase inhibitors
IL96619A0 (en) *	1989-12-11	1991-09-16	Rhone Poulenc Sante	Imidazole derivatives,process for their preparation and pharmaceutical compositions containing them
AU742293B2 (en)	1997-06-12	2001-12-20	Aventis Pharma Limited	Imidazolyl-cyclic acetals
CN107233337A (zh)	2009-04-29	2017-10-10	阿马里纳药物爱尔兰有限公司	含有epa和心血管剂的药物组合物以及使用其的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1178242A (en) *	1966-02-05	1970-01-21	Wellcome Found	Novel Biologically Active Bis-Isothioureas
DE2823197A1 (de) *	1978-05-24	1979-11-29	Schering Ag	Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US4188397A (en) *	1978-09-22	1980-02-12	Smithkline Corporation	2,2-Alkyldiylbis(thio)bis(imidazoles)
GR71915B (da) *	1979-11-27	1983-08-16	Pfizer

1986
- 1986-04-28 US US06/856,735 patent/US4728656A/en not_active Expired - Fee Related
- 1986-12-10 DK DK593986A patent/DK593986A/da not_active Application Discontinuation
- 1986-12-10 PT PT83903A patent/PT83903B/pt unknown
- 1986-12-11 EP EP86309674A patent/EP0229496B1/en not_active Expired - Lifetime
- 1986-12-11 DE DE8686309674T patent/DE3672254D1/de not_active Expired - Fee Related
- 1986-12-11 ES ES86309674T patent/ES2016263B3/es not_active Expired - Lifetime
- 1986-12-12 AU AU66453/86A patent/AU586056B2/en not_active Ceased
- 1986-12-12 JP JP61297443A patent/JPH072737B2/ja not_active Expired - Lifetime
1990
- 1990-09-12 GR GR90400642T patent/GR3000784T3/el unknown

Also Published As

Publication number	Publication date
JPH072737B2 (ja)	1995-01-18
ES2016263B3 (es)	1990-11-01
AU586056B2 (en)	1989-06-29
PT83903B (en)	1988-10-19
DE3672254D1 (de)	1990-08-02
US4728656A (en)	1988-03-01
EP0229496A1 (en)	1987-07-22
AU6645386A (en)	1987-06-18
EP0229496B1 (en)	1990-06-27
DK593986D0 (da)	1986-12-10
PT83903A (en)	1987-01-01
JPS62153285A (ja)	1987-07-08
GR3000784T3 (en)	1991-10-10

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Legal Events

Date	Code	Title	Description
1991-08-26	AHB	Application shelved due to non-payment