DK593986D0 - Forbindelser og farmaceutiske praeparater til inhibering af 5-lipoxygenase-vejen - Google Patents

Forbindelser og farmaceutiske praeparater til inhibering af 5-lipoxygenase-vejen

Info

Publication number
DK593986D0
DK593986D0 DK593986A DK593986A DK593986D0 DK 593986 D0 DK593986 D0 DK 593986D0 DK 593986 A DK593986 A DK 593986A DK 593986 A DK593986 A DK 593986A DK 593986 D0 DK593986 D0 DK 593986D0
Authority
DK
Denmark
Prior art keywords
lipoxygenase
inhibiting
road
compounds
pharmaceutical preparations
Prior art date
Application number
DK593986A
Other languages
English (en)
Other versions
DK593986A (da
Inventor
Poul Elliot Bender
David Taylor Hill
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of DK593986D0 publication Critical patent/DK593986D0/da
Publication of DK593986A publication Critical patent/DK593986A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK593986A 1985-12-12 1986-12-10 Forbindelser og farmaceutiske praeparater til inhibering af 5-lipoxygenase-vejen DK593986A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80839685A 1985-12-12 1985-12-12
US06/856,735 US4728656A (en) 1985-12-12 1986-04-28 2,2-alkyldiylbis(thio)bis(imidazoles) useful for inhibition of the 5-lipoxygenase pathway

Publications (2)

Publication Number Publication Date
DK593986D0 true DK593986D0 (da) 1986-12-10
DK593986A DK593986A (da) 1987-06-13

Family

ID=27123120

Family Applications (1)

Application Number Title Priority Date Filing Date
DK593986A DK593986A (da) 1985-12-12 1986-12-10 Forbindelser og farmaceutiske praeparater til inhibering af 5-lipoxygenase-vejen

Country Status (9)

Country Link
US (1) US4728656A (da)
EP (1) EP0229496B1 (da)
JP (1) JPH072737B2 (da)
AU (1) AU586056B2 (da)
DE (1) DE3672254D1 (da)
DK (1) DK593986A (da)
ES (1) ES2016263B3 (da)
GR (1) GR3000784T3 (da)
PT (1) PT83903B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4847270A (en) * 1985-12-12 1989-07-11 Smithkline Beckman Corporation Inhibition of the 5-lipoxygenase pathway utilizing certain 2,2'-alkyldiyl bis(thio)bis-imidazoles and derivatives
US5021440A (en) * 1989-07-31 1991-06-04 Merck & Co., Inc. Imidazole compounds and their use as transglutaminase inhibitors
US5030644A (en) * 1989-07-31 1991-07-09 Merck & Co., Inc. Imidazole compounds and their use as transglutaminase inhibitors
IL96619A0 (en) * 1989-12-11 1991-09-16 Rhone Poulenc Sante Imidazole derivatives,process for their preparation and pharmaceutical compositions containing them
EP0988301B1 (en) 1997-06-12 2006-08-09 Aventis Pharma Limited Imidazolyl-cyclic acetals
NZ720946A (en) 2009-04-29 2017-09-29 Amarin Pharmaceuticals Ie Ltd Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1178242A (en) * 1966-02-05 1970-01-21 Wellcome Found Novel Biologically Active Bis-Isothioureas
DE2823197A1 (de) * 1978-05-24 1979-11-29 Schering Ag Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US4188397A (en) * 1978-09-22 1980-02-12 Smithkline Corporation 2,2-Alkyldiylbis(thio)bis(imidazoles)
GR71915B (da) * 1979-11-27 1983-08-16 Pfizer

Also Published As

Publication number Publication date
JPH072737B2 (ja) 1995-01-18
PT83903B (en) 1988-10-19
AU586056B2 (en) 1989-06-29
AU6645386A (en) 1987-06-18
GR3000784T3 (en) 1991-10-10
DK593986A (da) 1987-06-13
JPS62153285A (ja) 1987-07-08
PT83903A (en) 1987-01-01
US4728656A (en) 1988-03-01
EP0229496B1 (en) 1990-06-27
ES2016263B3 (es) 1990-11-01
EP0229496A1 (en) 1987-07-22
DE3672254D1 (de) 1990-08-02

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment