DK59691D0 - Fremgangsmaade til fremstilling af liposomer med forbedret stabilitet under toerring - Google Patents

Fremgangsmaade til fremstilling af liposomer med forbedret stabilitet under toerring

Info

Publication number
DK59691D0
DK59691D0 DK91596A DK59691A DK59691D0 DK 59691 D0 DK59691 D0 DK 59691D0 DK 91596 A DK91596 A DK 91596A DK 59691 A DK59691 A DK 59691A DK 59691 D0 DK59691 D0 DK 59691D0
Authority
DK
Denmark
Prior art keywords
procedure
improved stability
stability under
under drying
preparing liposomes
Prior art date
Application number
DK91596A
Other languages
English (en)
Other versions
DK59691A (da
Inventor
Paul Gardner Schmidt
Gary Fujii
Original Assignee
Vestar Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vestar Inc filed Critical Vestar Inc
Publication of DK59691A publication Critical patent/DK59691A/da
Publication of DK59691D0 publication Critical patent/DK59691D0/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277Preparation processes; Proliposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/829Liposomes, e.g. encapsulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Cosmetics (AREA)
DK91596A 1988-10-05 1991-04-04 Fremgangsmaade til fremstilling af liposomer med forbedret stabilitet under toerring DK59691D0 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25368088A 1988-10-05 1988-10-05
PCT/US1989/004222 WO1990003795A1 (en) 1988-10-05 1989-10-03 Method of making liposomes with improved stability during drying

Publications (2)

Publication Number Publication Date
DK59691A DK59691A (da) 1991-04-04
DK59691D0 true DK59691D0 (da) 1991-04-04

Family

ID=22961272

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91596A DK59691D0 (da) 1988-10-05 1991-04-04 Fremgangsmaade til fremstilling af liposomer med forbedret stabilitet under toerring

Country Status (13)

Country Link
US (1) US5817334A (da)
EP (1) EP0437479B1 (da)
JP (1) JP2792702B2 (da)
AT (1) ATE107502T1 (da)
AU (1) AU612285B2 (da)
CA (1) CA2000219A1 (da)
DE (1) DE68916439T2 (da)
DK (1) DK59691D0 (da)
FI (1) FI902249A7 (da)
IE (1) IE64559B1 (da)
IL (1) IL91901A (da)
NO (1) NO180363C (da)
WO (1) WO1990003795A1 (da)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5705187A (en) * 1989-12-22 1998-01-06 Imarx Pharmaceutical Corp. Compositions of lipids and stabilizing materials
AU2583892A (en) * 1991-09-11 1993-04-05 Pitman-Moore, Inc. Method for enhancing the immune system in a host employing liposome-encapsulated polypeptides
JP3329554B2 (ja) * 1993-03-10 2002-09-30 千葉製粉株式会社 乾燥小胞体
DE4341472A1 (de) * 1993-12-02 1995-06-08 Schering Ag Verfahren zur Erhöhung der Stabilität von hydrophile Wirkstoffe enthaltenden Liposomensuspensionen
US5589189A (en) * 1994-09-14 1996-12-31 Nexstar Pharmaceuticals, Inc. Liposome dispersion
CA2202103C (en) * 1996-04-11 2007-01-09 Toshiaki Tagawa Method for preparing closed vesicles
RU2144352C1 (ru) * 1997-07-16 2000-01-20 Российский научно-исследовательский институт гематологии и трансфузиологии Способ получения лиофилизированных липосом
GB9813100D0 (en) * 1998-06-18 1998-08-19 Secr Defence Method of forming liposomes
AU775694B2 (en) * 1999-03-11 2004-08-12 Fujisawa Pharmaceutical Co., Ltd. Liposome preparations
CA2309373A1 (en) * 1999-05-27 2000-11-27 Johnson & Johnson Consumer Companies, Inc. Novel topical formulations
DK1059092T3 (da) * 1999-06-08 2006-03-27 Gentium Spa Anvendelse af komplekser af kationiske liposomer og polydeoxyribonukleotider som medikamenter
WO2000079283A1 (en) * 1999-06-23 2000-12-28 Cornell Research Foundation, Inc. Dehydration/rehydration of marked liposomes on a test device
US6576460B1 (en) 1999-10-28 2003-06-10 Cornell Research Foundation, Inc. Filtration-detection device and method of use
WO2002038128A1 (fr) * 2000-11-10 2002-05-16 Japan Science And Technology Corporation Procede de preparation d'une dispersion de microsome
US7125568B2 (en) 2001-08-23 2006-10-24 Sung Michael T Lipophilic drug compositions
US20050118250A1 (en) * 2001-11-13 2005-06-02 Paul Tardi Lipid carrier compositions with enhanced blood stability
EP1512010B1 (en) 2002-05-31 2008-01-02 Cornell Research Foundation, Inc. Universal biosensor and methods of use
DE10233632A1 (de) * 2002-07-24 2004-02-05 Wilex Ag Formulierungen von Phenylalanin-Derivaten
WO2004017944A1 (en) * 2002-08-23 2004-03-04 Neopharm, Inc. Liposomal gemcitabine compositions for better drug delivery
US7179484B2 (en) * 2002-11-06 2007-02-20 Azaya Therapeutics, Inc. Protein-stabilized liposomal formulations of pharmaceutical agents
EP1581201A4 (en) * 2002-12-23 2011-03-30 Vical Inc METHOD FOR PRODUCING STERILIC DRUGS ON POLYNUCLEOTIDE BASIS
CA2508279A1 (en) * 2002-12-23 2004-07-22 Vical Incorporated Method for freeze-drying nucleic acid/block copolymer/cationic surfactant complexes
WO2005020893A2 (en) * 2003-08-06 2005-03-10 The Regents Of The University Of California Therapeutic platelets and methods
ATE450251T1 (de) * 2004-05-17 2009-12-15 Tekmira Pharmaceuticals Corp Liposomale formulierungen mit dihydrosphingomyelin und verfahren zu ihrer verwendung
FR2870741B1 (fr) * 2004-05-25 2008-03-14 Coletica Sa Phase lamellaires hydratees ou liposomes, contenant une monoamine grasse ou un polymere cationique favorisant la penetration intercellulaire, et composition cosmetique ou pharmaceutique la contenant.
EP1809254A2 (en) * 2004-10-28 2007-07-25 Alza Corporation Lyophilized liposome formulations and method
WO2006068759A2 (en) * 2004-11-22 2006-06-29 Magellan Companies, Inc. Liposomes containing phytochemical agents and methods for making and using same
EP1932517A3 (en) * 2006-12-11 2008-07-16 Universiteit Utrecht Holding B.V. Liposomes containing a polyphenol derivative such as caffeic acid and a method of post-loading thereof
US20090047336A1 (en) * 2007-08-17 2009-02-19 Hong Kong Baptist University novel formulation of dehydrated lipid vesicles for controlled release of active pharmaceutical ingredient via inhalation
US8962015B2 (en) * 2007-09-28 2015-02-24 Sdg, Inc. Orally bioavailable lipid-based constructs
CN101485629B (zh) * 2008-01-16 2013-01-23 沈阳药科大学 一种给药系统及其制备方法
JP5903268B2 (ja) * 2008-07-24 2016-04-13 アモーレパシフィック コーポレイションAmorepacific Corporation 多層ラメラ顆粒、及びこれを含有する皮膚外用剤組成物
WO2010104883A1 (en) * 2009-03-09 2010-09-16 Molecular Express, Inc. Methods and compositions for liposomal formulation of antigens and uses thereof
US9775819B2 (en) * 2009-09-16 2017-10-03 R.P. Scherer Technologies, Llc Oral solid dosage form containing nanoparticles and process of formulating the same using fish gelatin
US9980765B2 (en) 2010-02-15 2018-05-29 The General Hospital Corporation Methods and devices for selective disruption of visceral fat by controlled cooling
EP2386647A1 (de) * 2010-05-10 2011-11-16 Qiagen GmbH Verfahren zur Transfektion einer eurkaryotischen Zelle
EP2471511A1 (en) 2011-01-04 2012-07-04 Archivel Farma, SL Liposome formulation suitable for treating or preventing tuberculosis
KR102284689B1 (ko) * 2011-10-21 2021-08-02 셀라토 파마슈티칼즈, 인코포레이티드 동결건조된 리포좀
US10076496B2 (en) * 2011-11-11 2018-09-18 The Chinese University Of Hong Kong Engineering of polymer-stabilized nanoparticles for drugs with Log P values below 6 by controlled antisolvent precipitation
EA022183B1 (ru) * 2012-12-24 2015-11-30 Общество С Ограниченной Ответственностью "Технология Лекарств" Способ получения липосомальной формы цитохрома с
US11471401B2 (en) 2014-08-28 2022-10-18 The General Hospital Corporation Injectable slurries and methods of manufacturing the same
PL3185854T3 (pl) 2014-08-28 2022-01-31 The General Hospital Corporation Zawiesiny do wstrzykiwań oraz sposoby ich wytwarzania i stosowania
US11504322B2 (en) 2014-08-28 2022-11-22 The General Hospital Corporation Injectable slurries and methods of manufacturing the same
CN109069288B (zh) 2016-02-26 2022-04-19 通用医疗公司 医用冰浆生产和递送系统和方法
JP2022542571A (ja) * 2019-07-24 2022-10-05 ザ ジェネラル ホスピタル コーポレイション カプセル化により異なる凝固点を有する物質を作製する方法
CN114886785B (zh) * 2022-06-07 2023-02-03 美尚(广州)化妆品股份有限公司 一种三元冻干组合物及其在冻干制剂中的应用

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5186117A (en) * 1975-01-27 1976-07-28 Tanabe Seiyaku Co Johoseibiryushiseizainoseiho
CH621479A5 (da) * 1977-08-05 1981-02-13 Battelle Memorial Institute
US4460577A (en) * 1977-09-30 1984-07-17 Farmitalia Carlo Erba S.P.A. Pharmaceutical compositions consisting or consisting essentially of liposomes, and processes for making same
FR2416008A1 (fr) * 1978-02-02 1979-08-31 Oreal Lyophilisats de liposomes
US4235871A (en) * 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4193983A (en) * 1978-05-16 1980-03-18 Syva Company Labeled liposome particle compositions and immunoassays therewith
US4377567A (en) * 1978-10-02 1983-03-22 The Procter & Gamble Company Lipid membrane drug delivery
CA1173360A (en) * 1979-06-22 1984-08-28 Jurg Schrank Pharmaceutical preparations
JPS574913A (en) * 1980-06-11 1982-01-11 Green Cross Corp:The Urokinase preparation for oral administration
US4460560A (en) * 1982-06-18 1984-07-17 University Of Southern California Drug delivery by polymeric carriers
AU1629383A (en) * 1982-10-02 1984-04-05 Amano Seiyaku K.K. Earthworm tissue protease thrombolytic agents
US4544545A (en) * 1983-06-20 1985-10-01 Trustees University Of Massachusetts Liposomes containing modified cholesterol for organ targeting
US4914084A (en) * 1984-05-09 1990-04-03 Synthetic Blood Corporation Composition and method for introducing heme, hemoproteins, and/or heme-hemoprotein complexes into the body
US5008109A (en) * 1984-05-25 1991-04-16 Vestar, Inc. Vesicle stabilization
US4880635B1 (en) * 1984-08-08 1996-07-02 Liposome Company Dehydrated liposomes
US4857319A (en) * 1985-01-11 1989-08-15 The Regents Of The University Of California Method for preserving liposomes
JPS62501631A (ja) * 1985-01-11 1987-07-02 ザ・リ−ジェンツ・オブ・ジ・ユニバ−シィティ・オブ・カリフォルニア リポソ−ムの保持法
CA1256372A (en) * 1985-04-11 1989-06-27 Koichiro Miyazima Process for producing liposome composition
US4735210A (en) * 1985-07-05 1988-04-05 Immunomedics, Inc. Lymphographic and organ imaging method and kit
US4766046A (en) * 1985-09-27 1988-08-23 Liposome Technology, Inc. Stabilized liposome/amphotericin composition and method
IE58981B1 (en) * 1985-10-15 1993-12-15 Vestar Inc Anthracycline antineoplastic agents encapsulated in phospholipid micellular particles
GB8604983D0 (en) * 1986-02-28 1986-04-09 Biocompatibles Ltd Protein preservation
US5089181A (en) * 1987-02-24 1992-02-18 Vestar, Inc. Method of dehydrating vesicle preparations for long term storage
KR900700079A (ko) * 1988-01-12 1990-08-11 후지하라 도미오 누출방지 리포좀 제제
JPH02273538A (ja) * 1989-04-13 1990-11-08 Fuji Photo Film Co Ltd リポソームの保存方法
US5705187A (en) * 1989-12-22 1998-01-06 Imarx Pharmaceutical Corp. Compositions of lipids and stabilizing materials

Also Published As

Publication number Publication date
EP0437479B1 (en) 1994-06-22
DK59691A (da) 1991-04-04
FI902249A0 (fi) 1990-05-04
JP2792702B2 (ja) 1998-09-03
FI902249A7 (fi) 1990-05-04
DE68916439D1 (de) 1994-07-28
DE68916439T2 (de) 1994-10-20
JPH04500803A (ja) 1992-02-13
AU612285B2 (en) 1991-07-04
NO901852L (no) 1990-08-01
IL91901A0 (en) 1990-06-10
AU4340089A (en) 1990-05-01
ATE107502T1 (de) 1994-07-15
US5817334A (en) 1998-10-06
NO180363C (no) 1997-04-09
NO180363B (no) 1996-12-30
CA2000219A1 (en) 1990-04-05
EP0437479A4 (en) 1991-10-16
EP0437479A1 (en) 1991-07-24
NO901852D0 (no) 1990-04-26
IE64559B1 (en) 1995-08-23
WO1990003795A1 (en) 1990-04-19
IE893196L (en) 1990-04-05
IL91901A (en) 1993-06-10

Similar Documents

Publication Publication Date Title
DK59691A (da) Fremgangsmaade til fremstilling af liposomer med forbedret stabilitet under toerring
ATE114156T1 (de) Herstellung von proteinen in aktiver form.
EP0283713A3 (en) Complexes of saponins with phospholipids and pharmaceutical and cosmetic compositions containing them
SE8903777L (sv) Liposome/doxorubicin, komposition och foerfarande
CA2113995A1 (en) Use of gentisic acid or gentisyl alcohol for stabilising radiolabeled peptides and proteins
EP0158277A3 (de) Implantierbare Zubereitungen von regulatorischen Peptiden mit gesteuerter Freisetzung und Verfahren zur ihrer Herstellung
TR199802789T2 (xx) Eksendin analoglar� bunlar�n �retimi i�in y�ntemler ve bunlar� i�eren farmas�tik m�stahzarlar.
IE881755L (en) Novel proteins with factor viii activity, process for their¹preparation using genetically engineered cells and¹pharmaceutical compositions containing them
DK164479C (da) Sucralfatsuspension og fremgangsmaade til fremstilling af denne
IT8620799A0 (it) Composizioni farmacueutiche adattivita' sequestrante degli acidi biliari contenenti colestiramina quale principio attivo, eprocedimento per prepararle.
FI102036B1 (fi) Menetelmä rasvaliukoisten aineiden stabiilien valmisteiden valmistamiseksi
EP0141374A3 (en) Capsule production using biologically active substrates
ES8305501A1 (es) Procedimiento para preparar un material de referencia o control de hemoglobina.
SE8204064L (sv) Vevnadslim samt sett for dess framstellning
NO922953D0 (no) Rekombinant fremstilt blodfaktorer og fremgangsmaate for ekspresjon av blodfaktorene, samt vacciniavirusrekombinanter
ES8607984A1 (es) Un procedimiento para cargar un polimero insoluble en agua yesponjable en agua con acetato de metilhidroxiprogesterona
ES8404160A1 (es) Un procedimiento para producir productos de plantas aromaticas.
EP0161007A3 (en) Retro - inverso c-terminal hexapeptide analogues of substance p
DK0740547T3 (da) Liposomer indeholdende deri indkapslede proteiner, fremgangsmåde til deres fremstilling, samt farmaceutiske og kosmetiske p
HUT35155A (en) Pesticide composition containing heterocyclic nitro-methylene derivatives as active substances and process for preparing the active substance
EP0261648A3 (en) Cell membrane proteins, compositions containing them and procedure for their preparation
NO881942L (no) Fremgangsmaate for fremstilling av fremmede proteiner i streptomyceten.
HUT33951A (en) Pesticide composition and process for producing tetrahydo-thio-pirane-3,5-dione-4-carboxamide derivatives utilizable as active agents
FI895899A7 (fi) Uudet trombolyyttiset proteiinit, menetelmä niiden valmistamiseksi ja näitä aktiiviaineina sisältävät lääkkeet
Salamah et al. Effect of the virulence associated 47 megadalton plasmid of Yersinia pestis on permeability to gentian violet and sensitivity to novobiocin