DK68585A - Fremgangsmaade til fremstilling af unilamellare liposomer - Google Patents

Fremgangsmaade til fremstilling af unilamellare liposomer Download PDF

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Publication number
DK68585A
DK68585A DK68585A DK68585A DK68585A DK 68585 A DK68585 A DK 68585A DK 68585 A DK68585 A DK 68585A DK 68585 A DK68585 A DK 68585A DK 68585 A DK68585 A DK 68585A
Authority
DK
Denmark
Prior art keywords
procedure
preparation
unilamelar
liposomes
unilamelar liposomes
Prior art date
Application number
DK68585A
Other languages
English (en)
Other versions
DK68585D0 (da
Inventor
Rene Muntwyler
Helmut Hauser
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK68585D0 publication Critical patent/DK68585D0/da
Publication of DK68585A publication Critical patent/DK68585A/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277Preparation processes; Proliposomes

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK68585A 1984-02-15 1985-02-14 Fremgangsmaade til fremstilling af unilamellare liposomer DK68585A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH73684 1984-02-15

Publications (2)

Publication Number Publication Date
DK68585D0 DK68585D0 (da) 1985-02-14
DK68585A true DK68585A (da) 1985-08-16

Family

ID=4194001

Family Applications (1)

Application Number Title Priority Date Filing Date
DK68585A DK68585A (da) 1984-02-15 1985-02-14 Fremgangsmaade til fremstilling af unilamellare liposomer

Country Status (7)

Country Link
EP (1) EP0152379A3 (da)
JP (1) JPS60190710A (da)
AU (1) AU588798B2 (da)
CA (1) CA1246446A (da)
DK (1) DK68585A (da)
ES (1) ES8607906A1 (da)
ZA (1) ZA851111B (da)

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DE3421468A1 (de) * 1984-06-08 1985-12-19 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim Lipidnanopellets als traegersystem fuer arzneimittel zur peroralen anwendung
JPS63501134A (ja) * 1985-10-21 1988-04-28 ザ リポソ−ム カンパニ−,インコ−ポレイテツド リポソ−ムの本来の調製及び配送
MY101125A (en) * 1985-12-23 1991-07-31 Kao Corp Gel-like emulsion and o/w emulsions obtained from gel-like emulsion
US5244678A (en) * 1986-01-14 1993-09-14 Ire-Celltarg S.A. Pharmaceutical composition containing a local anesthetic and/or centrally acting analgesic encapsulated in liposomes
FR2592791A1 (fr) * 1986-01-14 1987-07-17 Ire Celltarg Sa Composition pharmaceutique, contenant un anesthesique local et/ou un analgesique central encapsule dans des liposomes
DE3607339A1 (de) * 1986-03-06 1987-09-10 Merck Patent Gmbh Pharmazeutische zubereitung
SE8601457D0 (sv) * 1986-04-01 1986-04-01 Draco Ab Compositions of liposomes and b?712-receptor active substances for inhalation
DE3623193A1 (de) * 1986-07-10 1988-01-14 Gruenenthal Gmbh Neue verbindungen, diese enthaltende arzneimittel und verfahren zu deren herstellung
EP0265388A1 (de) * 1986-10-24 1988-04-27 Ciba-Geigy Ag Pyrrol-Derivate, therapeutische Mittel, die sie enthalten und ihre Verwendung
CH673395A5 (da) * 1987-01-30 1990-03-15 Ciba Geigy Ag
AU614527B2 (en) * 1987-07-24 1991-09-05 Nexstar Pharmaceuticals, Inc. Opioid analgesic liposomal delivery-release system
EP0380558A4 (en) * 1987-09-22 1991-07-31 The Regents Of The University Of California Liposomal nucleoside analogues for treating aids
US5830498A (en) * 1987-10-16 1998-11-03 Board Of Regents, The University Of Texas System Liposomal-polyene preliposomal powder and method for its preparation
US5178875A (en) * 1991-01-14 1993-01-12 The Board Of Regents, The University Of Texas System Liposomal-polyene preliposomal powder and method for its preparation
EP0472639A4 (en) * 1989-05-15 1992-07-01 The Liposome Company, Inc. Accumulation of drugs into liposomes by a proton gradient
FR2648462B1 (fr) * 1989-06-15 1994-01-28 Oreal Procede pour ameliorer l'efficacite therapeutique de corticosteroides liposolubles et composition pour la mise en oeuvre de ce procede
AT393955B (de) * 1990-03-30 1992-01-10 Martin Dr Leixnering Einrichtung zur nachbehandlung frischer beugesehnenverletzungen
IT1240354B (it) * 1990-03-30 1993-12-07 Poli Ind Chimica Spa Formulazioni liposomiali di farmaci antimicotici,antibatterici e/o antantiflogistici per applicazione locale e vaginale
DE4018767A1 (de) * 1990-06-12 1991-12-19 Braun Melsungen Ag Wirkstofffreie liposomen zur behandlung von atherosklerose
US5444076A (en) * 1990-11-26 1995-08-22 Roemmers S.A.I.C.F. Pharmaceutical preparation for topical application
DE4037554A1 (de) * 1990-11-26 1992-05-27 Roemmers Sa Arzneimittel zur topischen anwendung
AU664359B2 (en) * 1990-12-03 1995-11-16 Nexstar Pharmaceuticals, Inc. Prevention of synovial adhesions
GB9126209D0 (en) * 1991-12-10 1992-02-12 Orion Yhtymae Oy Drug formulations for parenteral use
GB9212450D0 (en) * 1992-06-11 1992-07-22 Indena Spa New derivatives of non-steroidal anti-inflammatory,analgesic and/or antipyretic substances,their use and pharmaceutical formulations containing them
NZ260408A (en) 1993-05-10 1996-05-28 Euro Celtique Sa Controlled release preparation comprising tramadol
WO1994028876A1 (en) * 1993-06-07 1994-12-22 Advanced Therapies, Inc. Liposome powders
US5891471A (en) * 1993-11-23 1999-04-06 Euro-Celtique, S.A. Pharmaceutical multiparticulates
KR100354702B1 (ko) * 1993-11-23 2002-12-28 유로-셀티크 소시에떼 아노뉨 약학조성물의제조방법및서방형조성물
US5843480A (en) * 1994-03-14 1998-12-01 Euro-Celtique, S.A. Controlled release diamorphine formulation
GB9422154D0 (en) 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5965161A (en) 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
AU713025B2 (en) * 1995-03-17 1999-11-18 Ciba Specialty Chemicals Holding Inc. Liposomogenic UV absorbers
FR2732895B1 (fr) * 1995-04-11 1997-05-16 Pasteur Merieux Serums Vacc Utilisation d'un compose amphipathique cationique comme agent de transfection, comme adjuvant de vaccin, ou comme medicament
US5731339A (en) * 1995-04-28 1998-03-24 Zonagen, Inc. Methods and formulations for modulating the human sexual response
GB9605915D0 (en) * 1996-03-21 1996-05-22 Univ Bruxelles Liposome encapsulated amphiphilic drug compositions
EP0834304B1 (de) * 1996-09-17 2005-01-26 Ciba SC Holding AG Verwendung liposomogener UV-Absorber zum Schutz des Haars
DE19959689A1 (de) * 1998-12-04 2000-06-08 Max Delbrueck Centrum Mittel zur Tumortherapie
DE69825495T2 (de) 1998-12-23 2005-07-28 Idea Ag Verbesserte formulierung zur topischen, nichtinvasiven anwendung in vivo
SI1031347T1 (en) 1999-01-27 2002-10-31 Idea Ag Transnasal transport/immunisation with highly adaptable carriers
PT1031346E (pt) 1999-01-27 2002-09-30 Idea Ag Vacinacao nao invasiva atraves da pele
DE19918325A1 (de) 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
WO2001001962A1 (en) 1999-07-05 2001-01-11 Idea Ag. A method for the improvement of transport across adaptable semi-permeable barriers
US20040105881A1 (en) 2002-10-11 2004-06-03 Gregor Cevc Aggregates with increased deformability, comprising at least three amphipats, for improved transport through semi-permeable barriers and for the non-invasive drug application in vivo, especially through the skin
CN101889981A (zh) * 2003-11-20 2010-11-24 Ym生物科学有限公司 包含含有药物成分的亲脂胺的稳定脂质体组合物
AT500143A1 (de) * 2004-04-22 2005-11-15 Sanochemia Pharmazeutika Ag Cholinesterase-inhibitoren in liposomen sowie deren herstellung und verwendung
US20090238763A1 (en) 2006-07-09 2009-09-24 Chongxi Yu High penetration compositions and uses thereof
CN103922946A (zh) * 2006-07-09 2014-07-16 于崇曦 带有正电荷的水溶性阿司匹林前药
US20090221703A1 (en) 2006-07-09 2009-09-03 Chongxi Yu High penetration composition and uses thereof
CA2656858C (en) * 2006-07-09 2016-01-19 Techfields Biochem Co. Ltd Positively charged water-soluble prodrugs of acetylsalicylic acid
AU2013206215C9 (en) * 2006-07-09 2018-03-08 Techfields Biochem Co. Ltd Positively charged water-soluble prodrugs of aspirin
AU2016219617B2 (en) * 2006-07-09 2018-05-17 Techfields Biochem Co. Ltd Positively charged water-soluble prodrugs of aspirin
KR20150058566A (ko) 2007-06-04 2015-05-28 테크필즈 인크 매우 높은 피부 및 막 침투율을 가지는 nsaia 약물전구체 및 이들의 새로운 의약적 용도
BR122021011394B1 (pt) 2008-12-04 2021-09-28 Chongxi Yu Composição de alta penetração de um fármaco principal, e uso de uma hpc
CN111012914A (zh) 2012-01-18 2020-04-17 苏州泰飞尔医药有限公司 治疗肺部疾病的高穿透力前药组合物和医药组合物
JP6289438B2 (ja) * 2015-12-03 2018-03-07 テックフィールズ バイオケム カンパニー リミテッド アスピリンの正荷電水溶性プロドラッグ
JP6588485B2 (ja) * 2017-02-21 2019-10-09 テックフィールズ バイオケム カンパニー リミテッド アスピリンの正荷電水溶性プロドラッグ
GB2571696B (en) 2017-10-09 2020-05-27 Compass Pathways Ltd Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced
US12459965B2 (en) 2017-10-09 2025-11-04 Compass Pathfinder Limited Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
JP2018058899A (ja) * 2018-01-04 2018-04-12 テックフィールズ バイオケム カンパニー リミテッド アスピリンの正荷電水溶性プロドラッグ
US12377112B2 (en) 2019-04-17 2025-08-05 Compass Pathfinder Limited Methods of treating neurocognitive disorders, chronic pain and reducing inflammation
US12240813B2 (en) 2020-05-19 2025-03-04 Cybin Irl Limited Deuterated tryptamine derivatives and methods of use

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5186117A (en) * 1975-01-27 1976-07-28 Tanabe Seiyaku Co Johoseibiryushiseizainoseiho
JPS5782310A (en) * 1980-11-11 1982-05-22 Tanabe Seiyaku Co Ltd Production of liposome preparation
IL64397A0 (en) * 1981-01-07 1982-02-28 Weder Hans G Process for the preparation of liposomal medicaments
DE3374837D1 (en) * 1982-02-17 1988-01-21 Ciba Geigy Ag Lipids in the aqueous phase
EP0102324A3 (de) * 1982-07-29 1984-11-07 Ciba-Geigy Ag Lipide und Tenside in wässriger Phase
JPS607932A (ja) * 1983-06-29 1985-01-16 Dai Ichi Seiyaku Co Ltd リポソーム懸濁液およびその製法
JPS60208910A (ja) * 1984-03-31 1985-10-21 Green Cross Corp:The 水難溶性薬物・リン脂質複合体の製造方法

Also Published As

Publication number Publication date
ES8607906A1 (es) 1986-06-01
ES540372A0 (es) 1986-06-01
CA1246446A (en) 1988-12-13
AU3875385A (en) 1985-08-22
EP0152379A2 (de) 1985-08-21
EP0152379A3 (de) 1986-10-29
ZA851111B (en) 1985-09-25
DK68585D0 (da) 1985-02-14
JPS60190710A (ja) 1985-09-28
AU588798B2 (en) 1989-09-28

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