DK73278A - Fremgangsmaade til fremstilling af ( +,-)-cis-alfa-(3-(2,6-dimethyl-1-piperidinyl)-alfaphenyl-2-pyridinmethanol eller syreadditionssalte heraf - Google Patents

Fremgangsmaade til fremstilling af ( +,-)-cis-alfa-(3-(2,6-dimethyl-1-piperidinyl)-alfaphenyl-2-pyridinmethanol eller syreadditionssalte heraf

Info

Publication number
DK73278A
DK73278A DK73278A DK73278A DK73278A DK 73278 A DK73278 A DK 73278A DK 73278 A DK73278 A DK 73278A DK 73278 A DK73278 A DK 73278A DK 73278 A DK73278 A DK 73278A
Authority
DK
Denmark
Prior art keywords
alfaphenyl
pyridinmethanol
alfa
piperidinyl
cis
Prior art date
Application number
DK73278A
Other languages
English (en)
Other versions
DK143229C (da
DK143229B (da
Inventor
R W Fleming
Original Assignee
Parke Davis & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/772,203 external-priority patent/US4112103A/en
Application filed by Parke Davis & Co filed Critical Parke Davis & Co
Publication of DK73278A publication Critical patent/DK73278A/da
Publication of DK143229B publication Critical patent/DK143229B/da
Application granted granted Critical
Publication of DK143229C publication Critical patent/DK143229C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/16—Radicals substituted by halogen atoms or nitro radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK73278A 1977-02-25 1978-02-17 Analogifremgangsmaade til fremstilling af (+,-)-cis-alfa-(3-(2,6-dimethyl-1-piperidinyl)propyl)-alfa-phenyl-2-pyridinmethanol eller syreadditionssalte heraf DK143229C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/772,203 US4112103A (en) 1976-04-15 1977-02-25 Antiarrhythmic (+,-)-cis-α-[3-(2,6-dimethyl-1-piperidinyl)propyl]-α-phenyl-2-pyridinemethanols
US77220377 1977-02-25

Publications (3)

Publication Number Publication Date
DK73278A true DK73278A (da) 1978-08-26
DK143229B DK143229B (da) 1981-07-27
DK143229C DK143229C (da) 1981-11-30

Family

ID=25094280

Family Applications (1)

Application Number Title Priority Date Filing Date
DK73278A DK143229C (da) 1977-02-25 1978-02-17 Analogifremgangsmaade til fremstilling af (+,-)-cis-alfa-(3-(2,6-dimethyl-1-piperidinyl)propyl)-alfa-phenyl-2-pyridinmethanol eller syreadditionssalte heraf

Country Status (11)

Country Link
JP (1) JPS53105479A (da)
AT (1) AT358040B (da)
BE (1) BE864033A (da)
CA (1) CA1096382A (da)
CH (1) CH635095A5 (da)
DE (1) DE2806654A1 (da)
DK (1) DK143229C (da)
ES (1) ES467100A1 (da)
FR (1) FR2381761A1 (da)
GB (1) GB1581096A (da)
PH (1) PH13125A (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2818914B2 (ja) * 1991-04-05 1998-10-30 シャープ株式会社 多目的スチーム発生器
CN116514770B (zh) * 2023-05-09 2025-02-07 郑州大学 2-苄基吡啶高效制备吡美诺的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE757408A (fr) * 1969-10-13 1971-04-13 Thomae Gmbh Dr K Nouveaux butanols tertiaires a constituants basiques

Also Published As

Publication number Publication date
JPS6257632B2 (da) 1987-12-02
DE2806654C2 (da) 1987-07-16
DK143229C (da) 1981-11-30
DE2806654A1 (de) 1978-08-31
CA1096382A (en) 1981-02-24
PH13125A (en) 1979-12-12
GB1581096A (en) 1980-12-10
FR2381761A1 (fr) 1978-09-22
CH635095A5 (en) 1983-03-15
BE864033A (fr) 1978-06-16
FR2381761B1 (da) 1982-03-26
AT358040B (de) 1980-08-11
DK143229B (da) 1981-07-27
ES467100A1 (es) 1978-11-01
ATA117078A (de) 1980-01-15
JPS53105479A (en) 1978-09-13

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