DK83886D0 - Pyrazolanaloge af mevalonolacton og derivater deraf, fremgangsmaader til fremstilling deraf og deres anvendelse - Google Patents

Pyrazolanaloge af mevalonolacton og derivater deraf, fremgangsmaader til fremstilling deraf og deres anvendelse

Info

Publication number
DK83886D0
DK83886D0 DK83886A DK83886A DK83886D0 DK 83886 D0 DK83886 D0 DK 83886D0 DK 83886 A DK83886 A DK 83886A DK 83886 A DK83886 A DK 83886A DK 83886 D0 DK83886 D0 DK 83886D0
Authority
DK
Denmark
Prior art keywords
3alkyl
phenoxy
fluoro
chloro
trifluoromethyl
Prior art date
Application number
DK83886A
Other languages
English (en)
Other versions
DK83886A (da
DK157543C (da
DK157543B (da
Inventor
James Richard Wareing
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of DK83886A publication Critical patent/DK83886A/da
Publication of DK83886D0 publication Critical patent/DK83886D0/da
Publication of DK157543B publication Critical patent/DK157543B/da
Application granted granted Critical
Publication of DK157543C publication Critical patent/DK157543C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F13/00—Interconnection of, or transfer of information or other signals between, memories, input/output devices or central processing units
    • G06F13/38—Information transfer, e.g. on bus
    • G06F13/382—Information transfer, e.g. on bus using universal interface adapter
    • G06F13/387—Information transfer, e.g. on bus using universal interface adapter for adaptation of different data processing systems to different peripheral devices, e.g. protocol converters for incompatible systems, open system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F13/00—Interconnection of, or transfer of information or other signals between, memories, input/output devices or central processing units
    • G06F13/38—Information transfer, e.g. on bus
    • G06F13/40—Bus structure
    • G06F13/4004—Coupling between buses
    • G06F13/4009—Coupling between buses with data restructuring
    • G06F13/4018—Coupling between buses with data restructuring with data-width conversion

Landscapes

  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Theoretical Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Computer Hardware Design (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK083886A 1984-06-22 1986-02-21 Pyrazolanaloge af mevalonolacton og derivater deraf samt deres anvendelse DK157543C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US62339384A 1984-06-22 1984-06-22
US62339384 1984-06-22
EP8500293 1985-06-18
PCT/EP1985/000293 WO1986000307A2 (en) 1984-06-22 1985-06-18 Pyrazole analogs of mevalonolactone and derivatives thereof, processes for their production and their use

Publications (4)

Publication Number Publication Date
DK83886A DK83886A (da) 1986-02-21
DK83886D0 true DK83886D0 (da) 1986-02-21
DK157543B DK157543B (da) 1990-01-22
DK157543C DK157543C (da) 1990-06-11

Family

ID=24497918

Family Applications (1)

Application Number Title Priority Date Filing Date
DK083886A DK157543C (da) 1984-06-22 1986-02-21 Pyrazolanaloge af mevalonolacton og derivater deraf samt deres anvendelse

Country Status (19)

Country Link
EP (1) EP0200736B1 (da)
JP (1) JPS61502467A (da)
KR (1) KR890001651B1 (da)
AT (1) ATE62906T1 (da)
AU (1) AU573368B2 (da)
CA (1) CA1249283A (da)
DE (1) DE3582674D1 (da)
DK (1) DK157543C (da)
ES (1) ES8703842A1 (da)
FI (1) FI860755A0 (da)
GR (1) GR851510B (da)
HU (1) HU198711B (da)
IL (1) IL75583A (da)
MY (1) MY101903A (da)
NZ (1) NZ212501A (da)
PL (1) PL151016B1 (da)
PT (1) PT80674B (da)
WO (1) WO1986000307A2 (da)
ZA (1) ZA854719B (da)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4668794A (en) * 1985-05-22 1987-05-26 Sandoz Pharm. Corp. Intermediate imidazole acrolein analogs
AU598775B2 (en) * 1985-10-25 1990-07-05 Sandoz Ag Heterocyclic analogs of mevalonolactone
JPS6322056A (ja) * 1986-04-30 1988-01-29 サンド・アクチエンゲゼルシヤフト オレフイン性化合物の製造法
US4808621A (en) * 1986-07-07 1989-02-28 Warner-Lambert Company Trans-6-[2-(N-heteroaryl-3,5-disubstituted)pyrazol-4-yl)-ethyl]- or ethenyl]tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis
IL83821A0 (en) * 1986-09-10 1988-02-29 Sandoz Ag Azaindole and indolizine derivatives,their production and pharmaceutical compositions containing them
US4751235A (en) * 1986-12-23 1988-06-14 Sandoz Pharm. Corp. Anti-atherosclerotic indolizine derivatives
US4735958A (en) * 1986-12-22 1988-04-05 Warner-Lambert Company Trans-6-[2-[2-(substituted-phenyl)-3- (or 4-) heteroaryl-5-substituted-1H-pyrrol-1-yl]-ethyl]tetrahydro-4-hydroxy-2H-pyran-2-one inhibitors of cholesterol biosynthesis
US4898949A (en) * 1987-02-25 1990-02-06 Bristol-Myers Company Intermediates for the preparation of antihypercholesterolemic tetrazole compounds
US4897490A (en) * 1987-02-25 1990-01-30 Bristol-Meyers Company Antihypercholesterolemic tetrazole compounds
AT401518B (de) * 1987-02-25 1996-09-25 Bristol Myers Squibb Co Neue tetrazol-verbindungen und verfahren zu ihrer herstellung
JP2569746B2 (ja) * 1987-08-20 1997-01-08 日産化学工業株式会社 キノリン系メバロノラクトン類
CA1336714C (en) * 1987-08-20 1995-08-15 Yoshihiro Fujikawa Quinoline type mevalonolactone inhibitors of cholesterol biosynthesis
US4906624A (en) * 1987-09-08 1990-03-06 Warner-Lambert Company 6-(((Substituted)pyridin-3-yl)alkyl)-and alkenyl)-tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis
US4997837A (en) * 1987-09-08 1991-03-05 Warner-Lambert Company 6-(((substituted)pyridin-3-yl)alkyl)-and alkenyl)-tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis
DE3800785A1 (de) * 1988-01-09 1989-07-20 Hoechst Ag Substituierte 7-(pyridazin-5-yl)-3,5-dihydroxyheptan(en)- saeuren, ihre entsprechenden (delta)-lactone bzw. derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte
US4822799A (en) * 1988-01-27 1989-04-18 Sandoz Pharm. Corp. Pyrazolopyridine analogs of mevalonolactone and derivatives thereof useful for inhibiting cholesterol biosynthesis in mammals
NO890522L (no) * 1988-02-25 1989-08-28 Bayer Ag Substituerte imidazolinoner og imidazolinthioner.
JP2890448B2 (ja) * 1988-04-26 1999-05-17 日産化学工業株式会社 ピラゾロピリジン系メバロノラクトン類
US5024999A (en) * 1988-04-26 1991-06-18 Nissan Chemical Industries Ltd. Pyrazolopyridine type mevalonolactones useful as pharmaeuticals
MY105067A (en) * 1988-10-13 1994-07-30 Novartis Ag Process for the preparation of 7-substituted-hept-6-enoic and -heptanoic acids and derivatives and intermediates thereof.
JPH04270285A (ja) * 1988-11-14 1992-09-25 Nissan Chem Ind Ltd ピラゾロピリミジン系メバロノラクトン類
IT1237793B (it) * 1989-12-21 1993-06-17 Zambon Spa Composti attivi come inibitori dell'enzima hmg-coa reduttasi
US5134155A (en) * 1991-08-08 1992-07-28 Ortho Pharmaceutical Corporation Tetrahydroindazole, tetrahydrocyclopentapyrazole, and hexahydrocycloheptapyrazole compounds and their use as HMG-coA reductase inhibitors
WO1993006236A1 (en) * 1991-09-20 1993-04-01 Zeneca Limited Enzymatic production of optical isomers of tetrahydropyran-2-ones
US5335293A (en) * 1992-06-16 1994-08-02 Key Technology, Inc. Product inspection method and apparatus
EP1556032A1 (en) 2002-11-01 2005-07-27 Takeda Pharmaceutical Company Limited Agent for preventing or treating neuropathy
AU2005308575A1 (en) 2004-11-23 2006-06-01 Warner-Lambert Company Llc 7-(2h-pyrazol-3-yl)-3, 5-dihyroxy-heptanoic acid derivatives as HMG Co-A reductase inhibitors for the treatment of lipidemia
WO2006087630A2 (en) * 2005-02-16 2006-08-24 Warner-Lambert Company Llc OXYPYRAZOLE HMG Co-A REDUCTASE INHIBITORS
EP1775299A1 (en) * 2005-10-05 2007-04-18 LEK Pharmaceuticals D.D. Process for the synthesis of HMG-CoA reductase inhibitors
WO2007081019A1 (ja) * 2006-01-16 2007-07-19 Sankyo Agro Company, Limited （３－硫黄原子置換フェニル）ピラゾール誘導体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1261124B (de) * 1961-09-22 1968-02-15 Hoechst Ag Verfahren zur Herstellung von Pyrazolen
DE2920933A1 (de) * 1979-05-23 1980-12-04 Basf Ag 3-aryl-5-methyl-pyrazol-4-carbonsaeureester enthaltende herbizide
US4245106A (en) * 1979-07-05 1981-01-13 Monsanto Company Process for the preparation of 1-alkyl-3-aryl-4-pyrazolecarboxylates

Also Published As

Publication number Publication date
CA1249283A (en) 1989-01-24
GR851510B (da) 1985-11-25
FI860755A7 (fi) 1986-02-20
PT80674A (en) 1985-07-01
FI860755L (fi) 1986-02-20
PT80674B (en) 1987-03-17
DK83886A (da) 1986-02-21
EP0200736A1 (en) 1986-11-12
PL151016B1 (en) 1990-07-31
ES544407A0 (es) 1987-03-01
ES8703842A1 (es) 1987-03-01
MY101903A (en) 1992-02-15
AU573368B2 (en) 1988-06-02
DK157543C (da) 1990-06-11
ATE62906T1 (de) 1991-05-15
DE3582674D1 (de) 1991-05-29
DK157543B (da) 1990-01-22
WO1986000307A3 (en) 1986-04-10
KR860700253A (ko) 1986-08-01
AU4546685A (en) 1986-01-24
PL254121A1 (en) 1988-07-21
WO1986000307A2 (en) 1986-01-16
JPS61502467A (ja) 1986-10-30
ZA854719B (en) 1987-02-25
EP0200736B1 (en) 1991-04-24
IL75583A0 (en) 1985-10-31
FI860755A0 (fi) 1986-02-20
NZ212501A (en) 1988-06-30
HU198711B (en) 1989-11-28
HUT39178A (en) 1986-08-28
KR890001651B1 (ko) 1989-05-12
IL75583A (en) 1989-09-10

Similar Documents

Publication Publication Date Title
DK157543C (da) Pyrazolanaloge af mevalonolacton og derivater deraf samt deres anvendelse
DK369086D0 (da) Indenanaloge af mevalonolacton og derivater deraf
SE7903392L (sv) Basiska respektive katjonaktiva sulfonsyragrupphaltiga monoazo- eller disazoforeningar
DK165244C (da) Analogifremgangsmaade til fremstilling af 1,2,3-trisubstituerede indoler
WO1987002662A3 (en) Heterocyclic analogs of mevalonolactone and derivatives thereof, processes for their production and their use as pharmaceuticals
NO853604L (no) 3-amino-2-benzoyl-akrylsyrederivater og fremgangsm¨te til deres fremstilling.
ES8507111A1 (es) Un procedimiento para la preparacion de compuestos de 1,4-dihidropiridina.
ES529090A0 (es) Procedimiento para preparar analogos de mevalonolactona y derivados de los mismos
ES2010284A6 (es) Procedimiento para preparar derivados de tiourea.
ES2040222T3 (es) Procedimiento para preparar ciertas 2-benzoil-2,3,5-ciclohexanotrionas.
DK596883A (da) Optisk aktive phenoxypropionsyre-derivater, fremgangsmaader til deres fremstilling og deres anvendelse som herbicider
ES8201979A1 (es) Procedimiento para la obtencion de derivados de bifeni- lil-azoliletano
SE7908940L (sv) Nya acyl-1h-1,2,4-triazolderivat
ATE32339T1 (de) Imidazolkarbonsaeure derivate.
DK253483D0 (da) Fremgangsmade til fremstilling af benzhydrylsulfinylethylaminderivater
ES8603395A1 (es) "procedimiento para preparar derivados de acido n-(fenilme- tiltio-3-oxo-1-propil)-aminoacetico".
DK506885D0 (da) 3-amino-2,3-dihydro-1-benzoxepin-forbindelser og farmaceutiske praeparater indeholdende disse

Legal Events

Date Code Title Description
PBP Patent lapsed