DK98588A - Fremgangsmaade til fremstilling og isolering af (r)-2-hydroxy-4-phenylsmoersyre og -estere deraf - Google Patents

Fremgangsmaade til fremstilling og isolering af (r)-2-hydroxy-4-phenylsmoersyre og -estere deraf

Info

Publication number: DK98588A
Authority: DK; Denmark
Prior art keywords: acid; menthyl; hydroxy; esters; insulation
Prior art date: 1987-02-26

Application number

DK098588A

Other languages

English (en)

Other versions

DK98588D0 (da

DK169100B1 (da

Inventor

Gary A Flynn

Douglas W Beight

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-02-26

Filing date

1988-02-25

Publication date

1988-08-27

1988-02-25 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1988-02-25 Publication of DK98588D0 publication Critical patent/DK98588D0/da

1988-08-27 Publication of DK98588A publication Critical patent/DK98588A/da

1994-08-15 Application granted granted Critical

1994-08-15 Publication of DK169100B1 publication Critical patent/DK169100B1/da

Links

239000002253 acid Substances 0.000 title abstract 4
238000000034 method Methods 0.000 title abstract 2
238000009413 insulation Methods 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 3
PPKAIMDMNWBOKN-UHFFFAOYSA-N 2-Oxo-4-phenylbutyric acid Chemical compound OC(=O)C(=O)CCC1=CC=CC=C1 PPKAIMDMNWBOKN-UHFFFAOYSA-N 0.000 abstract 2
238000002425 crystallisation Methods 0.000 abstract 1
230000008025 crystallization Effects 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
230000003301 hydrolyzing effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/48—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK098588A 1987-02-26 1988-02-25 (L)-Menthyl-2-oxo-4-phenylbutyrat samt fremgangsmåde til fremstilling og isolering af i det væsentlige ren (R)-2-hydroxy-4-phenylsmørsyre og estere deraf DK169100B1 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US1910287A	1987-02-26	1987-02-26
US1910287		1987-02-26

Publications (3)

Publication Number	Publication Date
DK98588D0 DK98588D0 (da)	1988-02-25
DK98588A true DK98588A (da)	1988-08-27
DK169100B1 DK169100B1 (da)	1994-08-15

Family

ID=21791451

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK098588A DK169100B1 (da)	1987-02-26	1988-02-25	(L)-Menthyl-2-oxo-4-phenylbutyrat samt fremgangsmåde til fremstilling og isolering af i det væsentlige ren (R)-2-hydroxy-4-phenylsmørsyre og estere deraf

Country Status (9)

Country	Link
EP (1)	EP0280285B1 (da)
JP (1)	JP2652027B2 (da)
KR (1)	KR950013082B1 (da)
AT (1)	ATE80147T1 (da)
DE (1)	DE3874166T2 (da)
DK (1)	DK169100B1 (da)
ES (1)	ES2046220T3 (da)
GR (1)	GR3005588T3 (da)
IE (1)	IE61113B1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AT401513B (de) *	1994-12-22	1996-09-25	Chemie Linz Gmbh	Verfahren zur herstellung von 2-hydroxy-4-phenylbuttersäure
JP3915015B2 (ja) *	1995-08-22	2007-05-16	味の素株式会社	光学活性２−ヒドロキシ−４−アリール酪酸またはそのエステルの製造方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3663597A (en) *	1970-05-05	1972-05-16	American Home Prod	Process for the purification of cyclandelate
JPS5823861B2 (ja) *	1979-06-05	1983-05-18	工業技術院長	α−ケトエステルの不斉水素化方法

1988
- 1988-02-24 DE DE8888102763T patent/DE3874166T2/de not_active Expired - Fee Related
- 1988-02-24 KR KR1019880001899A patent/KR950013082B1/ko not_active Expired - Fee Related
- 1988-02-24 ES ES198888102763T patent/ES2046220T3/es not_active Expired - Lifetime
- 1988-02-24 EP EP88102763A patent/EP0280285B1/en not_active Expired - Lifetime
- 1988-02-24 AT AT88102763T patent/ATE80147T1/de not_active IP Right Cessation
- 1988-02-25 IE IE51688A patent/IE61113B1/en not_active IP Right Cessation
- 1988-02-25 JP JP63040907A patent/JP2652027B2/ja not_active Expired - Lifetime
- 1988-02-25 DK DK098588A patent/DK169100B1/da not_active IP Right Cessation
1992
- 1992-09-03 GR GR920401869T patent/GR3005588T3/el unknown

Also Published As

Publication number	Publication date
GR3005588T3 (da)	1993-06-07
IE61113B1 (en)	1994-10-05
EP0280285A3 (en)	1989-11-02
JPS63227549A (ja)	1988-09-21
DE3874166D1 (de)	1992-10-08
KR950013082B1 (ko)	1995-10-24
DE3874166T2 (de)	1993-03-25
IE880516L (en)	1988-08-26
EP0280285B1 (en)	1992-09-02
KR880009898A (ko)	1988-10-05
DK98588D0 (da)	1988-02-25
ES2046220T3 (es)	1994-02-01
JP2652027B2 (ja)	1997-09-10
EP0280285A2 (en)	1988-08-31
DK169100B1 (da)	1994-08-15
ATE80147T1 (de)	1992-09-15

Legal Events

Date	Code	Title	Description
1994-08-15	B1	Patent granted (law 1993)
2000-10-30	PBP	Patent lapsed

Publication	Publication Date	Title
NO824175L (no)	1983-06-13	Fremgangsmaate ved fremstilling av optisk aktive alfa-arylalkansyrer og estere og amider derav
DK434889A (da)	1990-03-03	Fremgangsmaade til fremstilling af optisk aktive 3-phenylglycidsyreestere
DK98588D0 (da)	1988-02-25	Fremgangsmaade til fremstilling og isolering af (r)-2-hydroxy-4-phenylsmoersyre og -estere deraf
DE3783901D1 (de)	1993-03-11	Verfahren zur enzymatischen trennung der optischen isomere von racemischen oxazolidinon-derivaten.
AU1844788A (en)	1989-01-05	Process for the preparation of 2-aryloxypropionic acids
DE3566535D1 (en)	1989-01-05	Process for the preparation of l-carnitine
ES8707174A1 (es)	1987-07-01	Un procedimiento para preparar esteres de acido trans-beta-benzoilacrilico
DK93089A (da)	1989-08-30	Fremgangsmaade til fremstilling af phthalazineddikesyreesterederivater og mellemprodukt ved fremsgangsmaaden
DK521785D0 (da)	1985-11-12	Fremgangsmaade til fremstilling af halogenerede 3,3-dimethyl-5-hexan-2-oner
ATE78015T1 (de)	1992-07-15	Verfahren zur herstellung von 3-phenyl-2methylpropanol und seinen p-substituierten alkylderivaten.
DE69319113D1 (de)	1998-07-16	Verbessertes verfahren zur herstellung von n-phenyl-n-methoxyacetyl-dl-alanin-methylesterderivaten
MY105302A (en)	1994-09-30	Process for dehydrating corticosteroid intermediates.
ES8605779A1 (es)	1986-03-01	Un procedimiento de preparacion del 2,6-dimetil-5-metoxicar-bonil-4-(2-nitrofenil)-1,4-dihidropiridina-3-carboxilato de isobutilo