DK99690A - Fremgangsmaade til rensning af protein - Google Patents

Fremgangsmaade til rensning af protein Download PDF

Info

Publication number: DK99690A
Authority: DK; Denmark
Prior art keywords: procedure; disclosed; technique; cleaning protein; impurities
Prior art date: 1987-10-23

Application number

DK099690A

Other languages

Danish (da)

English (en)

Other versions

DK99690D0 (da

Inventor

David Naveh

John Chu-Tay Tang

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-10-23

Filing date

1990-04-23

Publication date

1990-04-23

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22340970&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK99690(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1990-04-23 Application filed by Schering Corp filed Critical Schering Corp

1990-04-23 Publication of DK99690D0 publication Critical patent/DK99690D0/da

1990-04-23 Publication of DK99690A publication Critical patent/DK99690A/da

Links

238000000034 method Methods 0.000 title abstract 3
102000004169 proteins and genes Human genes 0.000 title abstract 2
108090000623 proteins and genes Proteins 0.000 title abstract 2
238000004140 cleaning Methods 0.000 title 1
239000012535 impurity Substances 0.000 abstract 2
NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 abstract 1
235000019750 Crude protein Nutrition 0.000 abstract 1
102000004457 Granulocyte-Macrophage Colony-Stimulating Factor Human genes 0.000 abstract 1
108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 abstract 1
239000003729 cation exchange resin Substances 0.000 abstract 1
238000004255 ion exchange chromatography Methods 0.000 abstract 1
238000000746 purification Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
- B01J39/26—Cation exchangers for chromatographic processes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Chemical Kinetics & Catalysis (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Enzymes And Modification Thereof (AREA)
Ultra Sonic Daignosis Equipment (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Treatment Of Liquids With Adsorbents In General (AREA)

DK099690A 1987-10-23 1990-04-23 Fremgangsmaade til rensning af protein DK99690A (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US11188687A	1987-10-23	1987-10-23
PCT/US1988/003589 WO1989003840A1 (en)	1987-10-23	1988-10-19	Method of purifying protein

Publications (2)

Publication Number	Publication Date
DK99690D0 DK99690D0 (da)	1990-04-23
DK99690A true DK99690A (da)	1990-04-23

Family

ID=22340970

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK099690A DK99690A (da)	1987-10-23	1990-04-23	Fremgangsmaade til rensning af protein

Country Status (21)

Country	Link
EP (2)	EP0313343B2 (no)
JP (1)	JPH0788395B2 (no)
KR (1)	KR930008447B1 (no)
CN (1)	CN1031943C (no)
AT (1)	ATE121418T1 (no)
AU (1)	AU626008B2 (no)
DE (1)	DE3853610T3 (no)
DK (1)	DK99690A (no)
ES (1)	ES2070855T5 (no)
FI (1)	FI103974B1 (no)
HU (1)	HU204537B (no)
IE (1)	IE72219B1 (no)
IL (1)	IL88118A (no)
MY (1)	MY108512A (no)
NO (1)	NO303451B1 (no)
NZ (1)	NZ226651A (no)
OA (1)	OA09787A (no)
PT (1)	PT88813B (no)
TN (1)	TNSN88111A1 (no)
WO (1)	WO1989003840A1 (no)
ZA (1)	ZA887862B (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2796388B2 (ja) *	1988-05-13	1998-09-10	アムジエン・インコーポレーテツド	Ｇ−ｃｓｆの精製方法
US7217689B1 (en)	1989-10-13	2007-05-15	Amgen Inc.	Glycosylation analogs of erythropoietin
US5110913A (en) *	1990-05-25	1992-05-05	Miles Inc.	Antibody purification method
US5463029A (en) *	1992-11-23	1995-10-31	Immunex Corporation	Purification of fusion proteins comprising GM-CSF and IL-3
JPH09502728A (ja) *	1993-09-15	1997-03-18	アルファセラピューティクコーポレイション	α▲下１▼−酸性糖タンパク質の精製方法及び精製物
US5808011A (en) *	1996-07-01	1998-09-15	Biopure Corporation	Method for chromatographic removal of prions
US7304150B1 (en)	1998-10-23	2007-12-04	Amgen Inc.	Methods and compositions for the prevention and treatment of anemia
JP4360758B2 (ja)	1999-04-08	2009-11-11	ジェネンテック・インコーポレーテッド	逆の電荷のポリペプチド類をベースにした組成物
ES2558303T3 (es)	2002-09-11	2016-02-03	Chugai Seiyaku Kabushiki Kaisha	Método de purificación de proteínas
DE10360841A1 (de) *	2003-12-20	2005-07-14	Henkel Kgaa	Helle, stabile, staub- und geruchsarme Enzymgranulate
AU2006223180B2 (en) *	2005-03-11	2011-11-24	Wyeth Llc	A method of weak partitioning chromatography
SE529259C2 (sv) *	2005-08-31	2007-06-12	Ge Healthcare Bio Sciences Ab	Tillverkning av kromarografimatriser, en kromarografimatris, en vätskekromatografikolonn, prcess för att isolera målföreningar och användning av en kromarografimatris för vätskekromatografi
JP5276004B2 (ja) *	2006-11-10	2013-08-28	マリーゴールバーンシーオー−オペレイティブシーオー．リミテッド	アンギオゲニンの調製方法
CN101556261B (zh) *	2009-05-25	2012-01-11	北京理工大学	微管内等电聚焦和剪断吹出培养测定微生物等电点的方法
CN101556260B (zh) *	2009-05-25	2012-01-11	北京理工大学	固定化pH梯度毛细管等电聚焦测定微生物等电点的方法
WO2013075740A1 (en) *	2011-11-23	2013-05-30	Sanofi	Antibody purification method
RU2648999C2 (ru) *	2011-12-22	2018-03-29	Дженентек, Инк.	Способы повышения эффективности этапов очистки белка, находящихся ниже по потоку, с использованием мембранной ионообменной хроматографии
NO2994485T3 (no)	2013-05-06	2018-06-09
EP3546475A1 (en)	2018-03-27	2019-10-02	Sanofi	Full flow-through process for purifying recombinant proteins

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4658018A (en) *	1984-03-13	1987-04-14	Immunex Corporation	Process for producing homogeneous colony stimulating factor
IL76360A0 (en) *	1984-09-26	1986-01-31	Takeda Chemical Industries Ltd	Mutual separation of proteins
ZA872781B (en) *	1986-05-19	1987-10-05	Immunology Ventures	B-cell stimulating factor

1988
- 1988-10-19 EP EP88309824A patent/EP0313343B2/en not_active Expired - Lifetime
- 1988-10-19 AT AT88309824T patent/ATE121418T1/de not_active IP Right Cessation
- 1988-10-19 AU AU26247/88A patent/AU626008B2/en not_active Ceased
- 1988-10-19 KR KR1019890701131A patent/KR930008447B1/ko not_active Expired - Fee Related
- 1988-10-19 HU HU886264A patent/HU204537B/hu not_active IP Right Cessation
- 1988-10-19 EP EP88909648A patent/EP0391934A1/en active Pending
- 1988-10-19 ES ES88309824T patent/ES2070855T5/es not_active Expired - Lifetime
- 1988-10-19 DE DE3853610T patent/DE3853610T3/de not_active Expired - Fee Related
- 1988-10-19 JP JP63508950A patent/JPH0788395B2/ja not_active Expired - Lifetime
- 1988-10-19 WO PCT/US1988/003589 patent/WO1989003840A1/en not_active Ceased
- 1988-10-20 TN TNTNSN88111A patent/TNSN88111A1/fr unknown
- 1988-10-20 IE IE316888A patent/IE72219B1/en not_active IP Right Cessation
- 1988-10-20 NZ NZ226651A patent/NZ226651A/xx unknown
- 1988-10-20 ZA ZA887862A patent/ZA887862B/xx unknown
- 1988-10-20 MY MYPI88001190A patent/MY108512A/en unknown
- 1988-10-20 PT PT88813A patent/PT88813B/pt not_active IP Right Cessation
- 1988-10-21 IL IL88118A patent/IL88118A/xx not_active IP Right Cessation
- 1988-10-21 CN CN88107266A patent/CN1031943C/zh not_active Expired - Fee Related
1990
- 1990-04-17 OA OA59777A patent/OA09787A/en unknown
- 1990-04-20 NO NO901769A patent/NO303451B1/no not_active IP Right Cessation
- 1990-04-23 FI FI902017A patent/FI103974B1/fi not_active IP Right Cessation
- 1990-04-23 DK DK099690A patent/DK99690A/da unknown

Also Published As

Publication number	Publication date
EP0313343A1 (en)	1989-04-26
HU204537B (en)	1992-01-28
ES2070855T5 (es)	2004-03-01
EP0313343B2 (en)	2003-07-23
DE3853610T3 (de)	2004-05-13
AU626008B2 (en)	1992-07-23
KR930008447B1 (ko)	1993-09-04
PT88813B (pt)	1993-01-29
HUT52783A (en)	1990-08-28
NZ226651A (en)	1990-09-26
IE72219B1 (en)	1997-04-09
JPH0788395B2 (ja)	1995-09-27
FI103974B (fi)	1999-10-29
KR890701618A (ko)	1989-12-22
NO303451B1 (no)	1998-07-13
WO1989003840A1 (en)	1989-05-05
ES2070855T3 (es)	1995-06-16
ZA887862B (en)	1989-06-28
OA09787A (en)	1994-04-15
IL88118A0 (en)	1989-06-30
CN1032661A (zh)	1989-05-03
MY108512A (en)	1996-10-31
IE883168L (en)	1989-04-23
IL88118A (en)	1993-06-10
AU2624788A (en)	1989-05-23
FI103974B1 (fi)	1999-10-29
DE3853610D1 (de)	1995-05-24
DK99690D0 (da)	1990-04-23
EP0313343B1 (en)	1995-04-19
ATE121418T1 (de)	1995-05-15
NO901769D0 (no)	1990-04-20
TNSN88111A1 (fr)	1990-07-10
FI902017A0 (fi)	1990-04-23
NO901769L (no)	1990-04-20
JPH03500649A (ja)	1991-02-14
CN1031943C (zh)	1996-06-05
EP0391934A1 (en)	1990-10-17
HU886264D0 (en)	1990-07-28
DE3853610T2 (de)	1995-08-31

Publication	Publication Date	Title
DK99690A (da)	1990-04-23	Fremgangsmaade til rensning af protein
ATE73856T1 (de)	1992-04-15	Reinigung, herstellung und verwendung von tumor- nekrosisfaktoren.
HUT39462A (en)	1986-09-29	Process for the purification of proteins
IT8547835A1 (it)	1986-09-20	Procedimento di purificazione di proteine ossee
FR2603581B1 (fr)	1993-08-13	Procede pour isoler et purifier des aminoacides par chromatographie
DK184088D0 (da)	1988-04-05	Fremgangsmaade til oprensning af et polypeptid
BR8605129A (pt)	1987-05-05	Processo para purificacao de uma proteina atraves de cromatografia de coluna e processo para purificar fator anti-hemofilico a partir de crioprecipitado de plasma
DE3672973D1 (de)	1990-08-30	Verfahren zur spezifischen abtrennung von lactose aus milch.
GB2015531A (en)	1979-09-12	Purification of bordetella proteins by chromatography
ES2125938T3 (es)	1999-03-16	Procedimiento para la reactivacion de proteinas membranales purificadas.
DE3678633D1 (de)	1991-05-16	Verfahren zur reinigung vom humanen tumornekrosefaktor.
DK436982A (da)	1983-04-03	Fremgangsmaade til forbedring af kvaliteten af valleprotein
DK0383645T3 (da)	1993-08-02	Fremgangsmåde til fremstilling af antihæmofilifaktor (FVIIIc) med meget høj renhed
DK0546127T3 (da)	1996-11-04	Biosyntetisk cerebrospinalvæskekontrol og fremgangsmåde til fremstilling deraf
DE3674575D1 (de)	1990-10-31	Verwendung von optisch-aktiven carboalkylierten aminoalkohole zur trennung von optischen isomeren.
ATE38660T1 (de)	1988-12-15	Verfahren zur reinigung von rohem trifluranil.