DZ3027A1 - Composés et procédés pour le traitement de l'asthme, de l'allergie et des troubles inflammatoires. - Google Patents

Composés et procédés pour le traitement de l'asthme, de l'allergie et des troubles inflammatoires.

Info

Publication number: DZ3027A1
Authority: DZ; Algeria
Prior art keywords: allergy; asthma; compounds; treatment; methods
Prior art date: 1999-03-26

Application number

DZ000053A

Other languages

English (en)

Inventor

Ralph Scannel

Pierre Chatelain

Anna Toy-Palmer

Edmond Differding

James Ellis

Marie-Agnes Lassoie

Michelle Young

Xiong Cal

Sajjat Hussoin

Gurmit Grewal

Timothy Lewis

Original Assignee

Ucb Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-03-26

Filing date

2000-03-25

Publication date

2004-03-27

2000-03-25 Application filed by Ucb Sa filed Critical Ucb Sa

2004-03-27 Application granted granted Critical

2004-03-27 Publication of DZ3027A1 publication Critical patent/DZ3027A1/fr

Links

206010020751 Hypersensitivity Diseases 0.000 title 1
208000026935 allergic disease Diseases 0.000 title 1
230000007815 allergy Effects 0.000 title 1
208000006673 asthma Diseases 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1
208000027866 inflammatory disease Diseases 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/14—Radicals substituted by nitrogen atoms not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Dermatology (AREA)
Immunology (AREA)
Ophthalmology & Optometry (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Pain & Pain Management (AREA)
Diabetes (AREA)
Otolaryngology (AREA)
Toxicology (AREA)
Hematology (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Furan Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DZ000053A 1999-03-26 2000-03-25 Composés et procédés pour le traitement de l'asthme, de l'allergie et des troubles inflammatoires. DZ3027A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US12652199P	1999-03-26	1999-03-26

Publications (1)

Publication Number	Publication Date
DZ3027A1 true DZ3027A1 (fr)	2004-03-27

Family

ID=22425273

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DZ000053A DZ3027A1 (fr)	1999-03-26	2000-03-25	Composés et procédés pour le traitement de l'asthme, de l'allergie et des troubles inflammatoires.

Country Status (37)

Country	Link
US (3)	US6451801B1 (fr)
EP (1)	EP1165533B1 (fr)
JP (2)	JP2002540198A (fr)
KR (1)	KR20020005635A (fr)
CN (3)	CN1560041A (fr)
AR (2)	AR020026A1 (fr)
AT (1)	ATE279401T1 (fr)
AU (1)	AU761422B2 (fr)
BG (1)	BG105909A (fr)
BR (1)	BR0009341A (fr)
CA (1)	CA2368090A1 (fr)
CO (1)	CO5180543A1 (fr)
CZ (1)	CZ20013471A3 (fr)
DE (1)	DE60014876T2 (fr)
DZ (1)	DZ3027A1 (fr)
EE (2)	EE200400104A (fr)
ES (1)	ES2231164T3 (fr)
GT (1)	GT200000034A (fr)
HK (1)	HK1041880B (fr)
HU (1)	HUP0200613A2 (fr)
ID (1)	ID30430A (fr)
IL (1)	IL145481A0 (fr)
IS (2)	IS6077A (fr)
JO (1)	JO2250B1 (fr)
MX (1)	MXPA01009664A (fr)
NO (2)	NO20014648L (fr)
NZ (1)	NZ514291A (fr)
PA (1)	PA8493101A1 (fr)
PE (1)	PE20001566A1 (fr)
PL (1)	PL350845A1 (fr)
RU (1)	RU2241707C2 (fr)
SK (1)	SK13272001A3 (fr)
TR (2)	TR200401779T2 (fr)
UA (1)	UA69449C2 (fr)
WO (1)	WO2000058295A2 (fr)
YU (1)	YU68601A (fr)
ZA (1)	ZA200107642B (fr)

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US6894059B1 (en) *	1999-03-26	2005-05-17	Ucb S.A.	Compounds and methods for treatment of asthma, allergy and inflammatory disorders
US6686502B1 (en) *	1999-03-26	2004-02-03	Ucb S.A.	Compounds and methods for treatment of asthma, allergy and inflammatory disorders
PE20001566A1 (es) *	1999-03-26	2001-02-05	Ucb Sa	Piperazinas 1,4-sustituidas, piperidinas 1,4-sustituidas y 4-alquilidenilpiperidinas 1-sustituidas
US6864219B2 (en)	2000-01-17	2005-03-08	Bayer Aktiengesellschaft	Substituted aryl ketones
US6440994B1 (en) *	2000-03-29	2002-08-27	Richard J. Sanders, Jr.	Method of treating acne
GB0009479D0 (en) *	2000-04-17	2000-06-07	Cipla Limited	Antihistaminic compounds
ES2341236T3 (es) *	2002-03-27	2010-06-17	Sun Pharma Advanced Research Company Limited	Derivados de 4-(diarilmetil)-1-piperazinilo.
US7381821B2 (en)	2003-01-23	2008-06-03	Ucb, S.A.	Piperazine derivatives and their use as synthesis intermediates
EP1457485A1 (fr) *	2003-03-14	2004-09-15	Dompé S.P.A.	Acides sulfoniques, leurs dérivés ainsi que compositions pharmaceutiques les contenants
WO2006010283A1 (fr) *	2004-07-28	2006-02-02	Universität Zürich	Prevention et traitement de la formation de thrombus
KR100658436B1 (ko) *	2005-12-09	2006-12-27	한국화학연구원	아데노실코발라민 함유 피부질환 치료용 외용제 조성물
US20090247634A1 (en) *	2006-06-27	2009-10-01	Hans-Erik Claesson	Methods for identifying modulators of eoxin formation
DE602007011793D1 (de)	2006-10-18	2011-02-17	Pfizer Prod Inc	Biaryl-ether-harnstoffverbindungen
JP2011506441A (ja) *	2007-12-12	2011-03-03	アムジエン・インコーポレーテツド	グリシン輸送体−１阻害薬
PT2123277E (pt) *	2007-12-18	2011-04-20	Meiji Seika Kaisha	Agente preventivo ou terapêutico para doenças inflamatórias do intestino
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2000
- 2000-03-17 PE PE2000000236A patent/PE20001566A1/es not_active Application Discontinuation
- 2000-03-22 GT GT200000034A patent/GT200000034A/es unknown
- 2000-03-23 TR TR2004/01779T patent/TR200401779T2/xx unknown
- 2000-03-23 KR KR1020017012282A patent/KR20020005635A/ko not_active Ceased
- 2000-03-23 HU HU0200613A patent/HUP0200613A2/hu unknown
- 2000-03-23 AR ARP000101298A patent/AR020026A1/es not_active Application Discontinuation
- 2000-03-23 EP EP00912274A patent/EP1165533B1/fr not_active Expired - Lifetime
- 2000-03-23 WO PCT/BE2000/000026 patent/WO2000058295A2/fr not_active Ceased
- 2000-03-23 CN CNA2004100495405A patent/CN1560041A/zh active Pending
- 2000-03-23 CN CNB008068216A patent/CN1160344C/zh not_active Expired - Fee Related
- 2000-03-23 SK SK1327-2001A patent/SK13272001A3/sk unknown
- 2000-03-23 CA CA002368090A patent/CA2368090A1/fr not_active Abandoned
- 2000-03-23 AU AU34105/00A patent/AU761422B2/en not_active Ceased
- 2000-03-23 UA UA2001107287A patent/UA69449C2/uk unknown
- 2000-03-23 PL PL00350845A patent/PL350845A1/xx not_active Application Discontinuation
- 2000-03-23 IL IL14548100A patent/IL145481A0/xx unknown
- 2000-03-23 YU YU68601A patent/YU68601A/sh unknown
- 2000-03-23 DE DE60014876T patent/DE60014876T2/de not_active Expired - Fee Related
- 2000-03-23 RU RU2001129098/04A patent/RU2241707C2/ru not_active IP Right Cessation
- 2000-03-23 ES ES00912274T patent/ES2231164T3/es not_active Expired - Lifetime
- 2000-03-23 CZ CZ20013471A patent/CZ20013471A3/cs unknown
- 2000-03-23 HK HK02103566.6A patent/HK1041880B/en not_active IP Right Cessation
- 2000-03-23 ID IDW00200102070A patent/ID30430A/id unknown
- 2000-03-23 MX MXPA01009664A patent/MXPA01009664A/es active IP Right Grant
- 2000-03-23 NZ NZ514291A patent/NZ514291A/en unknown
- 2000-03-23 CN CNA2004100282269A patent/CN1528742A/zh active Pending
- 2000-03-23 EE EEP200400104A patent/EE200400104A/xx unknown
- 2000-03-23 JP JP2000607998A patent/JP2002540198A/ja not_active Withdrawn
- 2000-03-23 BR BR0009341-6A patent/BR0009341A/pt not_active IP Right Cessation
- 2000-03-23 EE EEP200100498A patent/EE200100498A/xx unknown
- 2000-03-23 AT AT00912274T patent/ATE279401T1/de not_active IP Right Cessation
- 2000-03-23 TR TR2001/02717T patent/TR200102717T2/xx unknown
- 2000-03-24 PA PA20008493101A patent/PA8493101A1/es unknown
- 2000-03-24 US US09/534,947 patent/US6451801B1/en not_active Expired - Fee Related
- 2000-03-24 CO CO00021428A patent/CO5180543A1/es not_active Application Discontinuation
- 2000-03-25 DZ DZ000053A patent/DZ3027A1/fr active
- 2000-03-27 JO JO200026A patent/JO2250B1/en active
2001
- 2001-09-17 ZA ZA200107642A patent/ZA200107642B/en unknown
- 2001-09-18 IS IS6077A patent/IS6077A/is unknown
- 2001-09-18 BG BG105909A patent/BG105909A/bg unknown
- 2001-09-25 NO NO20014648A patent/NO20014648L/no not_active Application Discontinuation
2002
- 2002-09-12 US US10/242,346 patent/US6797713B2/en not_active Expired - Fee Related
2003
- 2003-08-08 US US10/637,163 patent/US20040048875A1/en not_active Abandoned
2004
- 2004-07-05 IS IS7343A patent/IS7343A/is unknown
- 2004-07-06 NO NO20042861A patent/NO20042861L/no not_active Application Discontinuation
- 2004-07-12 JP JP2004204939A patent/JP2005002118A/ja not_active Withdrawn
- 2004-07-14 AR ARP040102477A patent/AR045991A2/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
US6797713B2 (en)	2004-09-28
US20030220347A1 (en)	2003-11-27
CN1528742A (zh)	2004-09-15
EE200400104A (et)	2004-10-15
EP1165533B1 (fr)	2004-10-13
ES2231164T3 (es)	2005-05-16
JP2002540198A (ja)	2002-11-26
GT200000034A (es)	2001-09-13
PE20001566A1 (es)	2001-02-05
RU2241707C2 (ru)	2004-12-10
US20040048875A1 (en)	2004-03-11
TR200401779T2 (tr)	2005-01-24
ATE279401T1 (de)	2004-10-15
IS6077A (is)	2001-09-18
EE200100498A (et)	2002-12-16
HK1041880A1 (en)	2002-07-26
SK13272001A3 (sk)	2002-05-09
NO20042861L (no)	2001-11-22
CO5180543A1 (es)	2002-07-30
PA8493101A1 (es)	2002-08-26
ZA200107642B (en)	2002-09-17
TR200102717T2 (tr)	2002-04-22
ID30430A (id)	2001-12-06
WO2000058295A3 (fr)	2001-02-08
AU761422B2 (en)	2003-06-05
DE60014876D1 (de)	2004-11-18
AU3410500A (en)	2000-10-16
CN1349521A (zh)	2002-05-15
HUP0200613A2 (en)	2002-06-29
UA69449C2 (uk)	2004-09-15
PL350845A1 (en)	2003-02-10
DE60014876T2 (de)	2005-10-20
US6451801B1 (en)	2002-09-17
IS7343A (is)	2004-07-05
JO2250B1 (en)	2004-10-07
BR0009341A (pt)	2002-02-19
AR020026A1 (es)	2002-03-27
AR045991A2 (es)	2005-11-23
HK1041880B (en)	2005-02-18
EP1165533A2 (fr)	2002-01-02
BG105909A (bg)	2002-05-31
NZ514291A (en)	2003-07-25
WO2000058295A2 (fr)	2000-10-05
CN1160344C (zh)	2004-08-04
NO20014648D0 (no)	2001-09-25
NO20014648L (no)	2001-11-22
YU68601A (sh)	2004-07-15
MXPA01009664A (es)	2002-08-12
JP2005002118A (ja)	2005-01-06
CN1560041A (zh)	2005-01-05
IL145481A0 (en)	2002-06-30
CZ20013471A3 (cs)	2002-06-12
KR20020005635A (ko)	2002-01-17
CA2368090A1 (fr)	2000-10-05

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