DZ3357A1 - Nouveaux médicaments composés de dibenzoazulène comme inhibiteurs de facteur onconécrosant - Google Patents

Nouveaux médicaments composés de dibenzoazulène comme inhibiteurs de facteur onconécrosant

Info

Publication number: DZ3357A1
Authority: DZ; Algeria
Prior art keywords: onconecrosive; dibenzoazulene; factor inhibitors; novel drugs; drugs composed
Prior art date: 2000-05-17

Application number

DZ013357A

Other languages

English (en)

Inventor

Mladen Mercep

Milan Mesic

Dijana Pesic

Zeljko Zupanovic

Boska Hrvacic

Original Assignee

Glaxosmithkline Zagreb

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-05-17

Filing date

2001-05-16

Publication date

2001-11-22

2001-05-16 Application filed by Glaxosmithkline Zagreb filed Critical Glaxosmithkline Zagreb

2001-11-22 Application granted granted Critical

2001-11-22 Publication of DZ3357A1 publication Critical patent/DZ3357A1/fr

Links

239000003814 drug Substances 0.000 title 1
229940079593 drug Drugs 0.000 title 1
239000003112 inhibitor Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Dermatology (AREA)
Immunology (AREA)
Pulmonology (AREA)
Rheumatology (AREA)
Ophthalmology & Optometry (AREA)
Pain & Pain Management (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

DZ013357A 2000-05-17 2001-05-16 Nouveaux médicaments composés de dibenzoazulène comme inhibiteurs de facteur onconécrosant DZ3357A1 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
HR20000310A HRP20000310A2 (en)	2000-05-17	2000-05-17	New dibenzoazulene compounds as tumor necrosis factor inhibitors
PCT/HR2001/000027 WO2001087890A1 (fr)	2000-05-17	2001-05-16	Utilisation de composes a base de thienodibenzoazulene comme inhibiteurs du facteur de necrose tumorale

Publications (1)

Publication Number	Publication Date
DZ3357A1 true DZ3357A1 (fr)	2001-11-22

Family

ID=10947110

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DZ013357A DZ3357A1 (fr)	2000-05-17	2001-05-16	Nouveaux médicaments composés de dibenzoazulène comme inhibiteurs de facteur onconécrosant

Country Status (36)

Country	Link
US (2)	US6897211B2 (fr)
EP (1)	EP1284977B1 (fr)
JP (1)	JP2003533528A (fr)
KR (1)	KR100823064B1 (fr)
CN (1)	CN1194976C (fr)
AR (1)	AR030562A1 (fr)
AT (1)	ATE434619T1 (fr)
AU (2)	AU2001256560B2 (fr)
BG (1)	BG65967B1 (fr)
BR (1)	BR0111202A (fr)
CA (1)	CA2409090C (fr)
CR (1)	CR6860A (fr)
CY (1)	CY1109328T1 (fr)
CZ (1)	CZ301770B6 (fr)
DE (1)	DE60139070D1 (fr)
DK (1)	DK1284977T3 (fr)
DZ (1)	DZ3357A1 (fr)
EA (1)	EA006069B1 (fr)
EE (1)	EE200200636A (fr)
ES (1)	ES2328335T3 (fr)
GE (1)	GEP20043304B (fr)
HR (1)	HRP20000310A2 (fr)
HU (1)	HUP0302295A3 (fr)
IL (1)	IL152809A0 (fr)
IS (1)	IS6621A (fr)
MA (1)	MA27125A1 (fr)
MX (1)	MXPA02011269A (fr)
NO (1)	NO20025510L (fr)
NZ (1)	NZ522553A (fr)
PL (1)	PL204849B1 (fr)
PT (1)	PT1284977E (fr)
RS (1)	RS50893B (fr)
SI (1)	SI1284977T1 (fr)
SK (1)	SK17702002A3 (fr)
WO (1)	WO2001087890A1 (fr)
ZA (1)	ZA200209180B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HRP20020303A8 (en)	2002-04-10	2009-03-31	GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o.	Benzonaphthoazulenes as inhibitors of tumour necrosis factor production and intermediates for the preparation thereof
HRP20020305A8 (en) *	2002-04-10	2009-03-31	GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o.	2-thia-dibenzoazulenes as inhibitors of tumour necrosis factor production and intermediates for the preparation thereof
HRP20020304B1 (en) *	2002-04-10	2008-04-30	GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o.	1-oxa-3-aza-dibenzoazulenes as inhibitors of tumor necrosis factor production and intermediates for the production thereof
HRP20020440B1 (en)	2002-05-21	2008-02-29	GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o.	1-aza-dibenzoazulenes as inhibitors of tumor necrosis factor production and intermediates for the preparation thereof
HRP20020441A2 (en) *	2002-05-21	2003-12-31	Pliva D D	1-oxa-dibenzoazulen as inhibitor of production of tumor necrosis factors and intermediate for preparation thereof
HRP20020453A2 (en)	2002-05-23	2003-12-31	Pliva D D	1,3-diaza-dibenzoazulen as inhibitor of production of tumor necrosis factors and intermediate for preparation thereof
HRP20020452A2 (en)	2002-05-23	2004-02-29	Pliva D D	1,2-diaza-dibenzoazulen as inhibitor of production of tumor necrosis factors and intermediates for preparation thereof
HRP20020451A2 (en) *	2002-05-23	2003-12-31	Pliva D D	1-tia-3-aza-dibenzoazulen as inhibitor of production of tumor necrosis factors and intermediates for preparation thereof
HRP20030160A2 (en) *	2003-03-06	2005-04-30	Pliva-Istra�iva�ki institut d.o.o.	1-thiadibenzoazulene derivatives and biological action thereof
HRP20030324A2 (en)	2003-04-24	2005-02-28	Pliva-Istra�iva�ki institut d.o.o.	Compounds of antiinflammatory effect
CA2575975A1 (fr) *	2003-11-12	2005-05-26	Dr. Reddy's Laboratories, Inc.	Preparation d'escitaloprame
HRP20030955A2 (en) *	2003-11-21	2005-08-31	Pliva-Istra�iva�ki institut d.o.o.	USE OF 1-OXADIBENZO[e,h]AZULENES FOR THE MANUFACTURE OF PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT AND PREVENTION OF CENTRAL NERVOUS SYSTEM DISEASES AND DISORDERS
HRP20030954A2 (en) *	2003-11-21	2005-08-31	Pliva D.D.	USE OF 1-AZA-DIBENZO[e,h]AZULENES FOR THE MANUFACTURENT AND PREVENTION OF CENTRAL NERVOUS SYSTEM DISEASES AND DISORDERS
HRP20040104A2 (en) *	2004-01-30	2005-10-31	Pliva-Istra�iva�ki institut d.o.o.	Use of benzonaphthoazulenes for the manufacture of pharmaceutical formulations for the treatment and prevention of central nervous system diseases and disorders
US20090048221A1 (en)	2004-10-27	2009-02-19	Mladen Mercep	Conjugates with Anti-Inflammatory Activity
RU2401257C2 (ru) *	2004-12-07	2010-10-10	Янссен Фармацевтика Н.В.	Новые замещенные тетрациклические производные тетрагидрофурана, пирролидина и тетрагидротиофена
JP2008532927A (ja) *	2005-01-13	2008-08-21	グラクソスミスクライン・イストラジヴァッキ・センタル・ザグレブ・ドルズバ・ゼー・オメイェノ・オドゴヴォルノスティオ	抗炎症マクロライド接合体
DK2026651T3 (da)	2006-03-08	2013-07-08	Cortria Corp	Kombinationsterapi med ikke-selektive COX-inhibitorer til forebyggelse af COX-relaterede maveskader
EP2114427B1 (fr)	2007-01-30	2014-06-25	New York University	Peptides destinés à être utilisés dans un traitement d'états associés à de l'oxyde nitrique
WO2008096755A1 (fr) *	2007-02-07	2008-08-14	Nippon Suisan Kaisha, Ltd.	Inhibiteur du récepteur vanilloïde (vr1) et son utilisation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3711489A (en) *	1971-03-31	1973-01-16	Pfizer	Certain 8,9-dihydro(3,4,7,8)cycloocta(1,2-d)imidazoles
JPS53116385A (en) *	1977-03-19	1978-10-11	Hokuriku Pharmaceutical	Pyrazin derivative and method for its production
US4198421A (en) *	1978-11-30	1980-04-15	E. I. Du Pont De Nemours And Company	Antiinflammatory 2-substituted-dibenzo[2,3:6,7]oxepino[4,5-d]imidazoles
DE69720709T2 (de) *	1996-04-12	2004-03-11	Janssen Pharmaceutica N.V.	Substituierte tetracyclische tetrahydrofuranderivate
GB9713368D0 (en) *	1997-06-25	1997-08-27	Weston Medical Ltd	Flame control
EP0887339A1 (fr) *	1997-06-27	1998-12-30	Boehringer Mannheim Gmbh	Dérivés de l'azulène et médicaments les contenant

2000
- 2000-05-17 HR HR20000310A patent/HRP20000310A2/hr not_active Application Discontinuation
2001
- 2001-05-16 RS YUP-841/02A patent/RS50893B/sr unknown
- 2001-05-16 GE GE5019A patent/GEP20043304B/en unknown
- 2001-05-16 EP EP01929882A patent/EP1284977B1/fr not_active Expired - Lifetime
- 2001-05-16 CA CA2409090A patent/CA2409090C/fr not_active Expired - Fee Related
- 2001-05-16 WO PCT/HR2001/000027 patent/WO2001087890A1/fr not_active Ceased
- 2001-05-16 HU HU0302295A patent/HUP0302295A3/hu unknown
- 2001-05-16 SK SK1770-2002A patent/SK17702002A3/sk unknown
- 2001-05-16 NZ NZ522553A patent/NZ522553A/en unknown
- 2001-05-16 DE DE60139070T patent/DE60139070D1/de not_active Expired - Lifetime
- 2001-05-16 KR KR1020027015567A patent/KR100823064B1/ko not_active Expired - Fee Related
- 2001-05-16 AU AU2001256560A patent/AU2001256560B2/en not_active Ceased
- 2001-05-16 CZ CZ20024090A patent/CZ301770B6/cs not_active IP Right Cessation
- 2001-05-16 JP JP2001584284A patent/JP2003533528A/ja active Pending
- 2001-05-16 EE EEP200200636A patent/EE200200636A/xx unknown
- 2001-05-16 AT AT01929882T patent/ATE434619T1/de not_active IP Right Cessation
- 2001-05-16 PL PL365054A patent/PL204849B1/pl not_active IP Right Cessation
- 2001-05-16 EA EA200201223A patent/EA006069B1/ru not_active IP Right Cessation
- 2001-05-16 CN CNB018115896A patent/CN1194976C/zh not_active Expired - Fee Related
- 2001-05-16 ES ES01929882T patent/ES2328335T3/es not_active Expired - Lifetime
- 2001-05-16 MX MXPA02011269A patent/MXPA02011269A/es active IP Right Grant
- 2001-05-16 IL IL15280901A patent/IL152809A0/xx unknown
- 2001-05-16 AU AU5656001A patent/AU5656001A/xx active Pending
- 2001-05-16 PT PT01929882T patent/PT1284977E/pt unknown
- 2001-05-16 DZ DZ013357A patent/DZ3357A1/fr active
- 2001-05-16 DK DK01929882T patent/DK1284977T3/da active
- 2001-05-16 BR BR0111202-3A patent/BR0111202A/pt not_active Application Discontinuation
- 2001-05-16 SI SI200130930T patent/SI1284977T1/sl unknown
- 2001-05-17 AR ARP010102339A patent/AR030562A1/es active IP Right Grant
2002
- 2002-11-11 MA MA26901A patent/MA27125A1/fr unknown
- 2002-11-12 ZA ZA200209180A patent/ZA200209180B/en unknown
- 2002-11-14 IS IS6621A patent/IS6621A/is unknown
- 2002-11-15 NO NO20025510A patent/NO20025510L/no not_active Application Discontinuation
- 2002-11-18 US US10/298,217 patent/US6897211B2/en not_active Expired - Fee Related
- 2002-12-17 BG BG107399A patent/BG65967B1/bg unknown
- 2002-12-17 CR CR6860A patent/CR6860A/es not_active Application Discontinuation
2005
- 2005-03-25 US US11/090,743 patent/US20050171091A1/en not_active Abandoned
2009
- 2009-08-20 CY CY20091100888T patent/CY1109328T1/el unknown

Also Published As

Publication number	Publication date
HRP20000310A2 (en)	2002-02-28
HK1056719A1 (en)	2004-02-27
DK1284977T3 (da)	2009-09-14
WO2001087890A1 (fr)	2001-11-22
RS50893B (sr)	2010-08-31
US20050171091A1 (en)	2005-08-04
AU2001256560B2 (en)	2005-10-06
EP1284977B1 (fr)	2009-06-24
MXPA02011269A (es)	2003-06-06
DE60139070D1 (de)	2009-08-06
KR20030010625A (ko)	2003-02-05
ATE434619T1 (de)	2009-07-15
US20030153750A1 (en)	2003-08-14
SK17702002A3 (sk)	2003-10-07
ZA200209180B (en)	2003-11-12
US6897211B2 (en)	2005-05-24
PT1284977E (pt)	2009-09-09
AU5656001A (en)	2001-11-26
BG65967B1 (bg)	2010-07-30
IS6621A (is)	2002-11-14
SI1284977T1 (sl)	2009-10-31
HUP0302295A2 (hu)	2003-10-28
CN1194976C (zh)	2005-03-30
NO20025510D0 (no)	2002-11-15
NO20025510L (no)	2003-01-14
PL204849B1 (pl)	2010-02-26
YU84102A (sh)	2006-01-16
BR0111202A (pt)	2003-04-01
KR100823064B1 (ko)	2008-04-18
BG107399A (bg)	2003-09-30
PL365054A1 (en)	2004-12-27
CN1437605A (zh)	2003-08-20
CA2409090A1 (fr)	2001-11-22
IL152809A0 (en)	2003-06-24
CA2409090C (fr)	2010-06-29
EE200200636A (et)	2004-04-15
AR030562A1 (es)	2003-08-27
CR6860A (es)	2008-06-02
GEP20043304B (en)	2004-02-10
MA27125A1 (fr)	2005-01-03
HUP0302295A3 (en)	2007-03-28
EP1284977A1 (fr)	2003-02-26
CZ301770B6 (cs)	2010-06-16
JP2003533528A (ja)	2003-11-11
CZ20024090A3 (cs)	2003-05-14
ES2328335T3 (es)	2009-11-12
EA200201223A1 (ru)	2003-06-26
EA006069B1 (ru)	2005-08-25
CY1109328T1 (el)	2012-05-23
NZ522553A (en)	2005-04-29

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