DZ3366A1 - Derives de 4,5-dihydro-thiazol-2-ylamine et leur utilisation comme inhibiteurs de no synthase - Google Patents

Derives de 4,5-dihydro-thiazol-2-ylamine et leur utilisation comme inhibiteurs de no synthase

Info

Publication number: DZ3366A1
Authority: DZ; Algeria
Prior art keywords: thiazol; dihydro; synthase inhibitors; ylamine derivatives; ylamine
Prior art date: 2000-06-09

Application number

DZ013366A

Other languages

English (en)

French (fr)

Inventor

Jean-Christophe Carry

Dominique Damour

Claude Guyon

Serge Mignani

Eric Bacque

Antony Bigot

Original Assignee

Aventis Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-06-09

Filing date

2001-06-07

Publication date

2001-12-13

2001-06-07 Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa

2001-12-13 Application granted granted Critical

2001-12-13 Publication of DZ3366A1 publication Critical patent/DZ3366A1/xx

Links

REGFWZVTTFGQOJ-UHFFFAOYSA-N 4,5-dihydro-1,3-thiazol-2-amine Chemical class NC1=NCCS1 REGFWZVTTFGQOJ-UHFFFAOYSA-N 0.000 title 1
239000003112 inhibitor Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/18—Nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Diabetes (AREA)
Cardiology (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Rheumatology (AREA)
Dermatology (AREA)
Pulmonology (AREA)
Psychology (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Toxicology (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Hematology (AREA)
Obesity (AREA)
Oncology (AREA)
Immunology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Communicable Diseases (AREA)
Vascular Medicine (AREA)

DZ013366A 2000-06-09 2001-06-07 Derives de 4,5-dihydro-thiazol-2-ylamine et leur utilisation comme inhibiteurs de no synthase DZ3366A1 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR0007396A FR2810036B1 (fr)	2000-06-09	2000-06-09	Derives de 4,5-dihydro-1,3-thiazol-2-ylamine, leur preparation et les compositions phamarceutiques les contenant
PCT/FR2001/001759 WO2001093867A1 (fr)	2000-06-09	2001-06-07	Derives de 4,5-dihydro-thiazol-2-ylamine et leur utilisation comme inhibiteurs de no synthase

Publications (1)

Publication Number	Publication Date
DZ3366A1 true DZ3366A1 (fr)	2001-12-13

Family

ID=8851133

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DZ013366A DZ3366A1 (fr)	2000-06-09	2001-06-07	Derives de 4,5-dihydro-thiazol-2-ylamine et leur utilisation comme inhibiteurs de no synthase

Country Status (27)

Country	Link
EP (1)	EP1299103B1 (no)
JP (1)	JP4171297B2 (no)
KR (1)	KR20030017990A (no)
CN (1)	CN1441673A (no)
AP (1)	AP2002002707A0 (no)
AT (1)	ATE305298T1 (no)
AU (2)	AU6612301A (no)
BR (1)	BR0111543A (no)
CA (1)	CA2411572C (no)
DE (1)	DE60113686T2 (no)
DK (1)	DK1299103T3 (no)
DZ (1)	DZ3366A1 (no)
EA (1)	EA200300009A1 (no)
EC (1)	ECSP024374A (no)
ES (1)	ES2246327T3 (no)
FR (1)	FR2810036B1 (no)
HR (1)	HRP20020971A2 (no)
HU (1)	HUP0300996A3 (no)
IL (1)	IL153327A0 (no)
MA (1)	MA25815A1 (no)
MX (1)	MXPA02012072A (no)
NO (1)	NO20025885L (no)
NZ (1)	NZ522967A (no)
OA (1)	OA12285A (no)
PL (1)	PL360282A1 (no)
WO (1)	WO2001093867A1 (no)
ZA (1)	ZA200209770B (no)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8088935B2 (en)	2003-12-23	2012-01-03	Ironwood Pharmaceuticals, Inc.	Compounds and methods for the treatment of asthma

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0670720A1 (en) *	1992-11-27	1995-09-13	The Wellcome Foundation Limited	Enzyme inhibitors
KR100342275B1 (ko) *	1993-10-21	2002-12-05	지.디. 썰 엘엘씨	산화질소신타제저해제로서유용한아미디노유도체
AU4149696A (en) *	1994-11-15	1996-06-06	Merck & Co., Inc.	Substituted heterocycles as inhibitors of nitric oxide synthase

2000
- 2000-06-09 FR FR0007396A patent/FR2810036B1/fr not_active Expired - Fee Related
2001
- 2001-06-07 KR KR1020027016786A patent/KR20030017990A/ko not_active Withdrawn
- 2001-06-07 OA OA1200200371A patent/OA12285A/fr unknown
- 2001-06-07 JP JP2002501440A patent/JP4171297B2/ja not_active Expired - Fee Related
- 2001-06-07 HR HR20020971A patent/HRP20020971A2/xx not_active Application Discontinuation
- 2001-06-07 ES ES01943579T patent/ES2246327T3/es not_active Expired - Lifetime
- 2001-06-07 BR BR0111543-0A patent/BR0111543A/pt not_active Application Discontinuation
- 2001-06-07 AP APAP/P/2002/002707A patent/AP2002002707A0/en unknown
- 2001-06-07 DZ DZ013366A patent/DZ3366A1/xx active
- 2001-06-07 AU AU6612301A patent/AU6612301A/xx active Pending
- 2001-06-07 IL IL15332701A patent/IL153327A0/xx unknown
- 2001-06-07 EP EP01943579A patent/EP1299103B1/fr not_active Expired - Lifetime
- 2001-06-07 PL PL36028201A patent/PL360282A1/xx unknown
- 2001-06-07 DK DK01943579T patent/DK1299103T3/da active
- 2001-06-07 NZ NZ522967A patent/NZ522967A/en unknown
- 2001-06-07 WO PCT/FR2001/001759 patent/WO2001093867A1/fr not_active Ceased
- 2001-06-07 HU HU0300996A patent/HUP0300996A3/hu unknown
- 2001-06-07 CN CN01812587A patent/CN1441673A/zh active Pending
- 2001-06-07 AU AU2001266123A patent/AU2001266123B2/en not_active Ceased
- 2001-06-07 EA EA200300009A patent/EA200300009A1/ru unknown
- 2001-06-07 CA CA002411572A patent/CA2411572C/fr not_active Expired - Fee Related
- 2001-06-07 DE DE60113686T patent/DE60113686T2/de not_active Expired - Lifetime
- 2001-06-07 AT AT01943579T patent/ATE305298T1/de not_active IP Right Cessation
- 2001-06-07 MX MXPA02012072A patent/MXPA02012072A/es active IP Right Grant
2002
- 2002-12-02 ZA ZA200209770A patent/ZA200209770B/en unknown
- 2002-12-06 NO NO20025885A patent/NO20025885L/no not_active Application Discontinuation
- 2002-12-09 EC EC2002004374A patent/ECSP024374A/es unknown
- 2002-12-09 MA MA26940A patent/MA25815A1/fr unknown

Also Published As

Publication number	Publication date
CA2411572A1 (fr)	2001-12-13
ES2246327T3 (es)	2006-02-16
HRP20020971A2 (en)	2005-02-28
JP2003535135A (ja)	2003-11-25
PL360282A1 (en)	2004-09-06
FR2810036B1 (fr)	2004-04-23
CN1441673A (zh)	2003-09-10
AU2001266123B2 (en)	2007-01-25
IL153327A0 (en)	2003-07-06
ZA200209770B (en)	2004-03-02
DK1299103T3 (da)	2006-01-23
NO20025885L (no)	2003-01-29
ATE305298T1 (de)	2005-10-15
DE60113686D1 (de)	2006-02-09
KR20030017990A (ko)	2003-03-04
AU6612301A (en)	2001-12-17
EA200300009A1 (ru)	2003-04-24
HUP0300996A3 (en)	2006-02-28
CA2411572C (fr)	2009-11-10
WO2001093867A1 (fr)	2001-12-13
AP2002002707A0 (en)	2002-12-31
EP1299103B1 (fr)	2005-09-28
MXPA02012072A (es)	2004-08-19
NO20025885D0 (no)	2002-12-06
BR0111543A (pt)	2003-07-01
FR2810036A1 (fr)	2001-12-14
DE60113686T2 (de)	2006-07-13
HUP0300996A2 (hu)	2003-08-28
EP1299103A1 (fr)	2003-04-09
MA25815A1 (fr)	2003-07-01
NZ522967A (en)	2005-07-29
ECSP024374A (es)	2003-02-06
JP4171297B2 (ja)	2008-10-22
OA12285A (en)	2006-05-12

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MA27001A1 (fr)	2004-12-20	Derives spirotricycliques nouveaux et leur utilisation comme inhibiteurs de phospho-diesterase-7
DZ3186A1 (fr)	2001-03-22	Ptéridinones utilisées comme inhibiteurs de kinase.
ID30460A (id)	2001-12-06	Inhibitor-inhibitor protein siklik tirosin kinase
FI20000121L (fi)	2001-07-21	Osoitteen hankinta
EP1161433A4 (en)	2002-05-08	TYROSINE KINASE INHIBITORS
PT1226136E (pt)	2005-04-29	Inibidores da tirosina quinase
MA26771A1 (fr)	2004-12-20	Benzoheterocycles et leur utilisation comme inhibiteurs de mek.
MXPA03004794A (es)	2003-09-10	Derivados de acido mandelico y su uso como inhibidores de trombina.
NL300242I1 (nl)	2006-12-01	Mega-carboxyaryl gesubstitueerde difenylureums alsraf kinaseremmers.
PT1181017E (pt)	2003-06-30	Inibidores de metaloproteases
AR028576A1 (es)	2003-05-14	Derivados de b-carbolina utiles como inhibidores de fosfodiesterasa
DK1244647T3 (da)	2006-09-25	Quinzolinderivater som VIGF-inhibitorer
SI1686119T1 (sl)	2009-12-31	Derivati pirimidin-5-ona kot inhibitorji ldl-pla2
DZ3439A1 (fr)	2001-12-13	Derives de 2-aminocarbonyl-9h-purine
DZ3415A1 (fr)	2002-03-07	Guanidinobenzamides comme mc4-r agonistes.
MA26976A1 (fr)	2004-12-20	Derives du tetrahydropyridine, leur preparation et leur utilisation comme inhibiteur de proliferation de cellules
MXPA03003314A (es)	2003-06-19	Compuestos de c-nitrosoanilina y sus mezclas como inhibidores de polimerizacion.
PT1194404E (pt)	2006-08-31	Inibidores de aspartil-protease
FR2806720B1 (fr)	2006-12-08	Derives de 2,2,6,6-diethyl-dimethyl-1-alcoxypiperidines et 1-oxydes correspondants
PT1171440E (pt)	2004-07-30	3-ciano-¬1,7\|,¬1,5\|, e ¬1,8\|-naftiridinas substituidas inibidoras de tirosina quinases
FR2810318B1 (fr)	2005-09-23	Derives de diamano-phenothiazine
IL148275A0 (en)	2002-09-12	Substituted 3-phenyl-5-alkoxy-1, 3, 4-oxdiazol-2-ones- and their use as lipase inhibitors
AR028607A1 (es)	2003-05-14	Derivados de 1,4-diazepan-2,5-diona
DE60032221D1 (de)	2007-01-18	Trokarsystem
MA25814A1 (fr)	2003-07-01	Derives de 2-aminothiazoline et leur utilisation comme inhibiteurs de no-synthase.