DZ615A1 - Composés nouveaux. - Google Patents

Composés nouveaux.

Info

Publication number
DZ615A1
DZ615A1 DZ847097A DZ847097A DZ615A1 DZ 615 A1 DZ615 A1 DZ 615A1 DZ 847097 A DZ847097 A DZ 847097A DZ 847097 A DZ847097 A DZ 847097A DZ 615 A1 DZ615 A1 DZ 615A1
Authority
DZ
Algeria
Prior art keywords
sup
new compounds
sub
salts
omeprazole
Prior art date
Application number
DZ847097A
Other languages
English (en)
French (fr)
Inventor
Arne Elof Brandstron
Original Assignee
Antiebolaget Hassle
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20350251&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DZ615(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Antiebolaget Hassle filed Critical Antiebolaget Hassle
Application granted granted Critical
Publication of DZ615A1 publication Critical patent/DZ615A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Inorganic Insulating Materials (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DZ847097A 1983-03-04 1984-03-04 Composés nouveaux. DZ615A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8301182A SE8301182D0 (sv) 1983-03-04 1983-03-04 Novel compounds

Publications (1)

Publication Number Publication Date
DZ615A1 true DZ615A1 (fr) 2004-09-13

Family

ID=20350251

Family Applications (1)

Application Number Title Priority Date Filing Date
DZ847097A DZ615A1 (fr) 1983-03-04 1984-03-04 Composés nouveaux.

Country Status (43)

Country Link
US (1) US4738974A (de)
EP (1) EP0124495B1 (de)
JP (1) JPS59167587A (de)
KR (1) KR870001005B1 (de)
AT (1) ATE24907T1 (de)
AU (1) AU563842B2 (de)
BG (2) BG44538A3 (de)
CA (1) CA1264751A (de)
CS (1) CS241150B2 (de)
DD (1) DD221459A5 (de)
DE (2) DE10199022I2 (de)
DK (1) DK160044C (de)
DZ (1) DZ615A1 (de)
ES (2) ES8500934B9 (de)
FI (1) FI83649C (de)
GB (1) GB2137616B (de)
GR (1) GR79828B (de)
HK (1) HK13590A (de)
HR (1) HRP930428B1 (de)
HU (1) HU193557B (de)
IE (1) IE57326B1 (de)
IL (1) IL70985A (de)
IS (1) IS1363B6 (de)
JO (1) JO1425B1 (de)
LT (1) LT2253B (de)
LU (1) LU90677I2 (de)
LV (2) LV5503A3 (de)
MA (1) MA20050A1 (de)
MY (1) MY102052A (de)
NL (1) NL300027I2 (de)
NO (2) NO160204C (de)
NZ (1) NZ207348A (de)
PH (1) PH21352A (de)
PL (1) PL142748B1 (de)
PT (1) PT78191B (de)
RO (1) RO88721A (de)
SA (1) SA92120418B1 (de)
SE (1) SE8301182D0 (de)
SG (1) SG1490G (de)
SI (1) SI8410397A8 (de)
SU (1) SU1314953A3 (de)
YU (1) YU43345B (de)
ZA (1) ZA841202B (de)

Families Citing this family (160)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5869513A (en) * 1985-05-24 1999-02-09 G. D. Searle & Co. 2- (1H-benzimidazol-2-ylsulfinyl)methyl!benzenamines
AU5768886A (en) 1985-05-24 1986-11-27 G.D. Searle & Co. 2-((1-h-benzimidazol-2-ylsulfinyl)methyl)benzenamines
US6749864B2 (en) * 1986-02-13 2004-06-15 Takeda Chemical Industries, Ltd. Stabilized pharmaceutical composition
JPS62277322A (ja) * 1986-02-13 1987-12-02 Takeda Chem Ind Ltd 安定化された腸溶性抗潰瘍固形組成物
US5433959A (en) * 1986-02-13 1995-07-18 Takeda Chemical Industries, Ltd. Stabilized pharmaceutical composition
CA1327010C (en) * 1986-02-13 1994-02-15 Tadashi Makino Stabilized solid pharmaceutical composition containing antiulcer benzimidazole compound and its production
GB2189698A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
GB2189699A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated acid-labile medicaments
US4772619A (en) * 1986-07-17 1988-09-20 G. D. Searle & Co. [(1H-benzimidazol-2-ylsulfinyl)methyl]-2-pyridinamines
US4687775A (en) * 1986-07-17 1987-08-18 G. D. Searle & Co. 2-[(Imidazo[1,2-a]pyridinylmethyl)sulfinyl]-1H-benzimidazoles
US4721718A (en) * 1986-08-18 1988-01-26 G. D. Searle & Co. 2-[(imidazo[1,2-a]pyridin-3-ylmethyl)sulfinyl]-1H-benzimidazoles useful in the treatment and prevention of ulcers
JP2536173B2 (ja) * 1988-08-18 1996-09-18 武田薬品工業株式会社 注射剤
WO1990003373A1 (fr) * 1988-09-20 1990-04-05 Hisamitsu Pharmaceutical Co., Inc. NOUVEAUX DERIVES DE DIBENZ[b,e]OXEPINE
IE64199B1 (en) * 1988-12-22 1995-07-12 Haessle Ab Compound with gastric acid inhibitory effect and process for its preparation
SE8804629D0 (sv) * 1988-12-22 1988-12-22 Ab Haessle New therapeutically active compounds
JP2694361B2 (ja) * 1989-02-09 1997-12-24 アストラ アクチエボラグ 抗菌剤
US5049674A (en) * 1989-12-20 1991-09-17 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
US5274099A (en) * 1989-12-20 1993-12-28 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
US4965269A (en) * 1989-12-20 1990-10-23 Ab Hassle Therapeutically active chloro substituted benzimidazoles
SE9002206D0 (sv) 1990-06-20 1990-06-20 Haessle Ab New compounds
ES2026761A6 (es) * 1990-10-31 1992-05-01 Genesis Para La Investigacion Procedimiento de obtencion del omeprazol.
RU2126252C1 (ru) * 1992-07-28 1999-02-20 Астра Актиеболаг Препарат для инъекций и набор для инъекций, содержащие омепразол и его аналоги
SE9301830D0 (sv) * 1993-05-28 1993-05-28 Ab Astra New compounds
US6875872B1 (en) 1993-05-28 2005-04-05 Astrazeneca Compounds
SE9302396D0 (sv) * 1993-07-09 1993-07-09 Ab Astra A novel compound form
SE9302395D0 (sv) * 1993-07-09 1993-07-09 Ab Astra New pharmaceutical formulation
TW359614B (en) * 1993-08-31 1999-06-01 Takeda Chemical Industries Ltd Composition containing benzimidazole compounds for rectal administration
TW280770B (de) * 1993-10-15 1996-07-11 Takeda Pharm Industry Co Ltd
EE03305B1 (et) 1994-07-08 2000-12-15 Astra Aktiebolag Paljuosaline tableteeritud annusvorm I
GB9423968D0 (en) * 1994-11-28 1995-01-11 Astra Ab Resolution
CN1042423C (zh) * 1995-05-25 1999-03-10 常州市第四制药厂 奥美拉唑盐水合物及其制备方法
US6699885B2 (en) * 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
US6489346B1 (en) * 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6645988B2 (en) 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
SE508669C2 (sv) * 1996-04-26 1998-10-26 Astra Ab Nytt förfarande
SE510666C2 (sv) * 1996-12-20 1999-06-14 Astra Ab Nya Kristallmodifikationer
SE9702000D0 (sv) * 1997-05-28 1997-05-28 Astra Ab New pharmaceutical formulation
SE510650C2 (sv) * 1997-05-30 1999-06-14 Astra Ab Ny förening
US6747155B2 (en) 1997-05-30 2004-06-08 Astrazeneca Ab Process
SE510643C2 (sv) * 1997-06-27 1999-06-14 Astra Ab Termodynamiskt stabil omeprazol natrium form B
SI9700186B (sl) 1997-07-14 2006-10-31 Lek, Tovarna Farmacevtskih In Kemicnih Izdelkov, D.D. Nova farmacevtska oblika z nadzorovanim sproscanjem zdravilnih ucinkovin
US6096340A (en) * 1997-11-14 2000-08-01 Andrx Pharmaceuticals, Inc. Omeprazole formulation
US6174548B1 (en) 1998-08-28 2001-01-16 Andrx Pharmaceuticals, Inc. Omeprazole formulation
SE9704870D0 (sv) 1997-12-22 1997-12-22 Astra Ab New pharmaceutical formulation I
SE9704869D0 (sv) * 1997-12-22 1997-12-22 Astra Ab New pharmaceutical formulaton II
DE19801811B4 (de) * 1998-01-19 2004-12-23 Stada Arzneimittel Ag Pharmazeutische Zubereitung zur oralen Verabreichung
DK173431B1 (da) 1998-03-20 2000-10-23 Gea Farmaceutisk Fabrik As Farmaceutisk formulering omfattende en 2-[[(2-pyridinyl)methyl]sulfinyl]benzimidazol med anti-ulcusaktivitet samt fremgangs
US6048981A (en) * 1998-04-22 2000-04-11 Torcan Chemical Ltd. Magnesium omeprazole and process for its preparation
US6733778B1 (en) 1999-08-27 2004-05-11 Andrx Pharmaceuticals, Inc. Omeprazole formulation
SE9803772D0 (sv) 1998-11-05 1998-11-05 Astra Ab Pharmaceutical formulation
IL142703A (en) * 1998-11-10 2006-04-10 Astrazeneca Ab Crystalline form of omeprazole
UA72748C2 (en) 1998-11-10 2005-04-15 Astrazeneca Ab A novel crystalline form of omeprazole
SE9900274D0 (sv) * 1999-01-28 1999-01-28 Astra Ab New compound
IL130602A0 (en) 1999-06-22 2000-06-01 Dexcel Ltd Stable benzimidazole formulation
US6312723B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Pharmaceutical unit dosage form
US6369087B1 (en) 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6262085B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6780880B1 (en) 1999-08-26 2004-08-24 Robert R. Whittle FT-Raman spectroscopic measurement
US6312712B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Method of improving bioavailability
US6316020B1 (en) * 1999-08-26 2001-11-13 Robert R. Whittle Pharmaceutical formulations
US6262086B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Pharmaceutical unit dosage form
US6268385B1 (en) 1999-08-26 2001-07-31 Robert R. Whittle Dry blend pharmaceutical formulations
US6326384B1 (en) 1999-08-26 2001-12-04 Robert R. Whittle Dry blend pharmaceutical unit dosage form
US6228400B1 (en) 1999-09-28 2001-05-08 Carlsbad Technology, Inc. Orally administered pharmaceutical formulations of benzimidazole derivatives and the method of preparing the same
SE9903831D0 (sv) * 1999-10-22 1999-10-22 Astra Ab Formulation of substituted benzimidazoles
CA2290893C (en) 1999-11-16 2007-05-01 Bernard Charles Sherman Magnesium omeprazole
DE19959419A1 (de) 1999-12-09 2001-06-21 Ratiopharm Gmbh Stabile galenische Zubereitungen umfassend ein Benzimidazol und Verfahren zu ihrer Herstellung
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
US20030212274A1 (en) * 2000-05-15 2003-11-13 Bakthavathsalan Vijayaraghavan Novel amorphous form of omeprazole salts
US6306435B1 (en) 2000-06-26 2001-10-23 Yung Shin Pharmaceutical Industrial Co. Ltd. Oral pharmaceutical preparation embedded in an oily matrix and methods of making the same
JP5412023B2 (ja) * 2000-08-04 2014-02-12 武田薬品工業株式会社 ベンズイミダゾール化合物の塩およびその用途
CA2386716C (en) * 2002-05-17 2012-07-24 Bernard Charles Sherman Magnesium salt of s-omeprazole
MY137726A (en) 2000-11-22 2009-03-31 Nycomed Gmbh Freeze-dried pantoprazole preparation and pantoprazole injection
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
US20040006111A1 (en) * 2002-01-25 2004-01-08 Kenneth Widder Transmucosal delivery of proton pump inhibitors
ES2286408T3 (es) 2002-03-05 2007-12-01 Astrazeneca Ab Sales de alquilamonio de omeprazol e esomeprazol.
TW200410955A (en) 2002-07-29 2004-07-01 Altana Pharma Ag Novel salt of (S)-PANTOPRAZOLE
EP1546131A1 (de) 2002-08-30 2005-06-29 Dr. Reddy's Laboratories Ltd. Amorphe hydrate von esomeprazol-magnesium und verfahren zu deren herstellung
BR0315574A (pt) * 2002-10-22 2005-09-20 Ranbaxy Lab Ltd Forma amorfa de esomeprazol, composição farmacêutica contendo o mesmo e processo para sua preparação
JP2006513239A (ja) * 2002-12-23 2006-04-20 セルテック アメリカズ， インコーポレイテッド 酸不安定性薬剤含有組成物
US20040248942A1 (en) * 2003-02-20 2004-12-09 Bonnie Hepburn Novel formulation, omeprazole antacid complex-immediate release for rapid and sustained suppression of gastric acid
US7507746B2 (en) 2003-02-24 2009-03-24 Mitsubishi Pharma Corporation Enantiomer of tenatoprazole and the use thereof in therapy
DE602004032524D1 (de) 2003-03-24 2011-06-16 Eisai R&D Man Co Ltd Verfahren zur herstellung von amorphem rabeprazole-natrium-salz
WO2004099182A1 (en) * 2003-05-05 2004-11-18 Ranbaxy Laboratories Limited Zinc salt of (s)-omeprazole
EP1633736A1 (de) * 2003-05-05 2006-03-15 Ranbaxy Laboratories Limited Barium salz eines benzimidazol-derivats
CA2531564C (en) * 2003-07-18 2016-01-19 Santarus, Inc. Pharmaceutical composition for inhibiting acid secretion
WO2005007117A2 (en) * 2003-07-18 2005-01-27 Santarus, Inc. Pharmaceutical formulation and method for treating acid-caused gastrointestinal disorders
US8993599B2 (en) * 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
CN100457104C (zh) * 2003-07-23 2009-02-04 尼科梅德有限责任公司 质子泵抑制剂的碱性盐
ATE386522T1 (de) * 2003-07-23 2008-03-15 Nycomed Gmbh Alkalisalze von protonenpumpen-hemmern
SE0302381D0 (sv) * 2003-09-04 2003-09-04 Astrazeneca Ab New salts I
SE0302382D0 (sv) 2003-09-04 2003-09-04 Astrazeneca Ab New salts II
TWI372066B (en) 2003-10-01 2012-09-11 Wyeth Corp Pantoprazole multiparticulate formulations
US20070292498A1 (en) * 2003-11-05 2007-12-20 Warren Hall Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers
SE0400410D0 (sv) 2004-02-20 2004-02-20 Astrazeneca Ab New compounds
WO2005082888A1 (en) * 2004-03-01 2005-09-09 Milen Merkez Ilac Endustrisi A.S. Process for the preparation of magnesium salt of omeprazole
US8815916B2 (en) * 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) * 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US20050267159A1 (en) * 2004-05-28 2005-12-01 Aaipharma, Inc. Magnesium complexes of S-omeprazole
ATE456566T1 (de) * 2004-05-28 2010-02-15 Hetero Drugs Ltd Neue stereoselektive synthese von benzimidazolsulfoxiden
FR2871800B1 (fr) * 2004-06-17 2006-08-25 Sidem Pharma Sa Sa Sel de sodium monohydrate du s-tenatoprazole et application en therapeutique
CN103121992A (zh) 2004-06-24 2013-05-29 阿斯利康(瑞典)有限公司 制备用于制备艾美拉唑钠盐的结晶修饰物的新方法
US20060024362A1 (en) 2004-07-29 2006-02-02 Pawan Seth Composition comprising a benzimidazole and process for its manufacture
AU2005268056B2 (en) 2004-08-06 2008-07-31 Eisai R&D Management Co., Ltd. Salts of benzimidazole derivative with amines and process for production thereof
WO2006067599A2 (en) 2004-12-23 2006-06-29 Ranbaxy Laboratories Limited Stable oral benzimidazole compositions and process of preparation thereof
US20060160783A1 (en) * 2004-12-30 2006-07-20 Transform Pharmaceuticals, Inc. Novel omeprazole forms and related methods
US20080279951A1 (en) * 2005-02-02 2008-11-13 Rajesh Gandhi Stable Oral Benzimidazole Compositions Prepared by Non-Aqueous Layering Process
US20090298884A1 (en) * 2005-05-06 2009-12-03 Glenmark Generics Ltd. Esomeprazole Strontium Salt, Process For Its Preparation and Pharmaceutical Compositions Containing Same
US7803817B2 (en) 2005-05-11 2010-09-28 Vecta, Ltd. Composition and methods for inhibiting gastric acid secretion
US7981908B2 (en) 2005-05-11 2011-07-19 Vecta, Ltd. Compositions and methods for inhibiting gastric acid secretion
WO2006131338A2 (en) * 2005-06-08 2006-12-14 Lek Pharmaceuticals D.D. Crystalline solvate of omeprazole sodium
EP1891043A1 (de) * 2005-06-15 2008-02-27 Hetero Drugs Limited Amorphes esomeprazol-hydrat
US20070043085A1 (en) * 2005-08-19 2007-02-22 Glenmark Pharmaceuticals Limited Process for the preparation of amorphous form of neutral esomeprazole
RU2372345C1 (ru) * 2005-10-26 2009-11-10 Ханми Фарм. Ко., Лтд. Стронциевая соль s-омепразола или ее гидрат, способ их получения и содержащая их фармацевтическая композиция
US7576219B2 (en) 2005-10-26 2009-08-18 Hanmi Pharm. Co., Ltd Crystalline S-omeprazole strontium hydrate, method for preparing same, and pharmaceutical composition containing same
EP1785135A1 (de) * 2005-11-10 2007-05-16 Laboratorios Del Dr. Esteve, S.A. Neue Lanzoprazol enthaltende stabilisierte galenische Formulierungen und ihre Herstellung
EP1801110A1 (de) 2005-12-22 2007-06-27 KRKA, tovarna zdravil, d.d., Novo mesto Argininsalz des Esomeprazols
ES2281292B1 (es) * 2006-03-08 2008-06-16 Quimica Sintetica S.A. Nuevas sales de esomeprazol. procedimiento de preparacion y composiciones farmaceuticas que las comprenden.
ES2355164T3 (es) * 2006-06-07 2011-03-23 Astrazeneca Ab Nuevo método para la preparación de sales de amonio de esomeprazol.
US7786309B2 (en) 2006-06-09 2010-08-31 Apotex Pharmachem Inc. Process for the preparation of esomeprazole and salts thereof
PL2046334T3 (pl) 2006-07-25 2015-02-27 Vecta Ltd Kompozycje i sposoby hamowania wydzielania kwasów żołądkowych z wykorzystaniem pochodnych małych kwasów dikarboksylowych w połączeniu z PPI
WO2008067037A2 (en) 2006-10-05 2008-06-05 Santarus, Inc. Novel formulations of proton pump inhibitors and methods of using these formulations
US20090092658A1 (en) * 2007-10-05 2009-04-09 Santarus, Inc. Novel formulations of proton pump inhibitors and methods of using these formulations
EP2086543A2 (de) 2006-10-27 2009-08-12 The Curators of the University of Missouri Zusammensetzungen mit mindestens einem säurelabilen protonenpumpen-hemmenden mittel, wahlweise anderen pharmazeutisch wirksamen mitteln und anwendungsverfahren dafür
TR201910825T4 (tr) 2006-12-22 2019-08-21 Ironwood Pharmaceuticals Inc Yemek borusu rahatsizliklarini tedavi̇ etmek i̇çi̇n yöntemler ve bi̇leşi̇mler
US20080194307A1 (en) * 2007-02-13 2008-08-14 Jeff Sanger Sports-based game of chance
WO2008102145A2 (en) * 2007-02-21 2008-08-28 Cipla Limited Process for the preparation of esomeprazole magnesium dihydrate
US8492551B2 (en) * 2007-06-07 2013-07-23 Aurobindo Pharma. Ltd. Process for preparing an optically active proton pump inhibitor
WO2009047775A2 (en) * 2007-10-08 2009-04-16 Hetero Drugs Limited Polymorphs of esomeprazole salts
JP2011512416A (ja) 2008-02-20 2011-04-21 ザ・キュレイターズ・オブ・ザ・ユニバーシティー・オブ・ミズーリ オメプラゾール及びランソプラゾールの組合せと緩衝剤を含んでなる組成物とそれを使用する方法
US8911787B2 (en) 2008-02-26 2014-12-16 Ranbaxy Laboratories Limited Stable oral benzimidazole compositions and process of preparation thereof
ES2552723T3 (es) 2008-05-06 2015-12-01 Dexcel Pharma Technologies Ltd. Formulación de bencimidazol estable
US20090280173A1 (en) * 2008-05-09 2009-11-12 Ishwar Chauhan Multilayer Omeprazole Tablets
US20090280175A1 (en) * 2008-05-09 2009-11-12 Ishwar Chauhan Multilayer Proton Pump Inhibitor Tablets
EP2147918A1 (de) 2008-07-21 2010-01-27 LEK Pharmaceuticals D.D. Verfahren zur Herstellung von S-Omeprazol-Magnesium in einer stabilen Form
CH699302B1 (de) * 2008-08-11 2012-03-15 Mepha Gmbh Orale pharmazeutische Formulierung für Omeprazol, enthaltend eine spezifische Trennschicht.
JP4906817B2 (ja) * 2008-08-29 2012-03-28 セイコークロック株式会社 装飾装置及びからくり時計
BRPI0918492A2 (pt) 2008-09-09 2015-12-01 Astrazeneca Ab uso de naproxen, ou sal farmaceuticamente aceitável do mesmo, e esomeprazol, ou sal farmaceuticamente aceitável do mesmo
WO2010058409A2 (en) * 2008-11-18 2010-05-27 Hetero Research Foundation Optical purification of esomeprazole
WO2010122583A2 (en) 2009-04-24 2010-10-28 Rubicon Research Private Limited Oral pharmaceutical compositions of acid labile substances
EP2445499A4 (de) 2009-06-25 2013-02-27 Astrazeneca Ab Verfahren zur behandlung eines patienten mit risiko der entwicklung eines nsaid-assoziierten geschwürs
AU2010266026B2 (en) * 2009-06-25 2014-08-07 Nuvo Pharmaceuticals (Ireland) Designated Activity Company Method for treating a patient in need of aspirin therapy
EP2499125B1 (de) 2009-11-12 2016-01-27 Hetero Research Foundation Verfahren zur racematspaltung von omeprazol
EP2345408A3 (de) 2010-01-08 2012-02-29 Dr. Reddy's Laboratories Ltd. Säurelabile Arzneimittelformulierungen
FR2967353B1 (fr) * 2010-11-16 2013-08-16 Centre Nat Rech Scient Derives de quinolinone
CN102351846B (zh) * 2011-09-07 2012-08-22 周晓东 一种新的奥美拉唑钠化合物及其药物组合物
WO2013081566A1 (en) 2011-11-25 2013-06-06 Mahmut Bilgic A formulation comprising benzimidazole
UA115139C2 (uk) 2011-12-28 2017-09-25 Поузен Інк. Спосіб доставки фармацевтичної композиції, яка містить омепразол й ацетилсаліцилову кислоту, пацієнту
CN104203938A (zh) 2012-01-21 2014-12-10 朱比兰特生命科学有限公司 用于制备2-吡啶基甲基亚硫酰基苯并咪唑、它们的类似物和光学活性对映体的方法
JP6716255B2 (ja) 2013-01-15 2020-07-01 アイロンウッド ファーマシューティカルズ，インコーポレーテッドＩｒｏｎｗｏｏｄ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． 胆汁酸捕捉剤の胃内滞留型徐放性経口剤形
ES2744406T3 (es) * 2013-02-13 2020-02-25 Redhill Biopharma Ltd Composiciones farmacéuticas para el tratamiento de helicobacter pylori
GB201306720D0 (en) 2013-04-12 2013-05-29 Special Products Ltd Formulation
US10130618B2 (en) 2014-04-11 2018-11-20 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Pharmaceutical combinations of dabigatran and proton pump inhibitors
WO2015155307A1 (en) 2014-04-11 2015-10-15 Sanovel Ilac Sanayi Ve Ticaret A.S. Pharmaceutical combinations of rivaroxaban and proton pump inhibitors
CN104045627A (zh) * 2014-05-21 2014-09-17 丽珠医药集团股份有限公司 一种奥美拉唑纯化方法
WO2016126625A1 (en) 2015-02-03 2016-08-11 Ironwood Pharmaceuticals, Inc. Methods of treating upper gastrointestinal disorders in ppi refractory gerd
WO2016174664A1 (en) 2015-04-29 2016-11-03 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
JP2025532389A (ja) 2022-10-04 2025-09-29 ザビリュク，アルセニー 大動脈弁の石灰化の抑制

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1234058A (de) * 1968-10-21 1971-06-03
US4045564A (en) * 1974-02-18 1977-08-30 Ab Hassle Benzimidazole derivatives useful as gastric acid secretion inhibitors
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
CA1085392A (en) * 1976-03-25 1980-09-09 Masayuki Narisada Arylmalonamido-1-oxadethiacephalosporins
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
US4472409A (en) * 1981-11-05 1984-09-18 Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects

Also Published As

Publication number Publication date
IL70985A (en) 1987-10-20
ES530242A0 (es) 1984-11-01
AU2525784A (en) 1984-09-06
KR870001005B1 (ko) 1987-05-18
IE57326B1 (en) 1992-07-29
LV5503A3 (lv) 1994-03-10
ES8500934B9 (es) 2012-01-03
KR840008014A (ko) 1984-12-12
BG60837B2 (bg) 1996-04-30
LT2253B (lt) 1993-11-15
YU39784A (en) 1986-12-31
DE10199022I1 (de) 2001-06-21
EP0124495A2 (de) 1984-11-07
JPH0313233B2 (de) 1991-02-22
FI840851A0 (fi) 1984-03-02
LV5801B4 (lv) 1997-12-20
IS2887A7 (is) 1984-09-05
DE10199022I2 (de) 2004-07-01
HRP930428B1 (en) 1996-04-30
NO160204C (no) 1989-03-22
IE840514L (en) 1984-09-04
LV5801A4 (lv) 1997-02-20
NZ207348A (en) 1986-10-08
AU563842B2 (en) 1987-07-23
DD221459A5 (de) 1985-04-24
GR79828B (de) 1984-10-31
BG44538A3 (bg) 1988-12-15
GB2137616B (en) 1986-11-12
GB2137616A (en) 1984-10-10
MY102052A (en) 1992-03-31
DE3462036D1 (en) 1987-02-19
NO840772L (no) 1984-09-05
SE8301182D0 (sv) 1983-03-04
NL300027I2 (nl) 2001-07-02
FI83649B (fi) 1991-04-30
SA92120418B1 (ar) 2003-12-23
PT78191B (en) 1986-08-05
NO2000010I1 (no) 2000-10-05
PL142748B1 (en) 1987-11-30
RO88721A (ro) 1986-04-30
EP0124495B1 (de) 1987-01-14
DK99584A (da) 1984-09-05
ES8500934A1 (es) 1984-11-01
FI840851L (fi) 1984-09-05
YU43345B (en) 1989-06-30
DK99584D0 (da) 1984-02-24
DK160044B (da) 1991-01-21
SI8410397A8 (sl) 1995-10-31
GB8405511D0 (en) 1984-04-04
SU1314953A3 (ru) 1987-05-30
PH21352A (en) 1987-10-15
NL300027I1 (nl) 2001-02-01
HU193557B (en) 1987-10-28
ATE24907T1 (de) 1987-01-15
MA20050A1 (fr) 1984-10-01
DK160044C (da) 1991-06-10
PT78191A (en) 1984-04-01
US4738974A (en) 1988-04-19
LU90677I2 (fr) 2001-02-05
ZA841202B (en) 1984-10-31
EP0124495A3 (en) 1985-05-15
CA1264751A (en) 1990-01-23
NO160204B (no) 1988-12-12
SG1490G (en) 1990-07-13
CS151584A2 (en) 1985-06-13
CS241150B2 (en) 1986-03-13
IS1363B6 (is) 1989-05-25
JPS59167587A (ja) 1984-09-21
HK13590A (en) 1990-03-02
FI83649C (fi) 1991-08-12
JO1425B1 (en) 1988-03-10
PL246492A1 (en) 1985-02-27

Similar Documents

Publication Publication Date Title
DZ615A1 (fr) Composés nouveaux.
MY101791A (en) New benzimidazole derivatives
KR890700125A (ko) 신규 벤즈이미다졸 유도체, 그 제조방법 및 이 화합물을 함유하는 제약 조성물
SE8405588D0 (sv) New compounds
ATE32514T1 (de) 3-(4'-aminobutylamino)-propylamino-bleomycinderivate, verfahren zur ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.