EA200200089A1 - Съедобные изделия с голографическим рисунком, в частности фармацевтические препараты, и способы и устройство для их получения - Google Patents

Съедобные изделия с голографическим рисунком, в частности фармацевтические препараты, и способы и устройство для их получения

Info

Publication number
EA200200089A1
EA200200089A1 EA200200089A EA200200089A EA200200089A1 EA 200200089 A1 EA200200089 A1 EA 200200089A1 EA 200200089 A EA200200089 A EA 200200089A EA 200200089 A EA200200089 A EA 200200089A EA 200200089 A1 EA200200089 A1 EA 200200089A1
Authority
EA
Eurasian Patent Office
Prior art keywords
layer
relief
dosage form
microrelief
molded
Prior art date
Application number
EA200200089A
Other languages
English (en)
Other versions
EA004895B1 (ru
Inventor
Эрик Беглейтер
Original Assignee
Дименшенэл Фудс Корпорейшн
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Дименшенэл Фудс Корпорейшн filed Critical Дименшенэл Фудс Корпорейшн
Publication of EA200200089A1 publication Critical patent/EA200200089A1/ru
Publication of EA004895B1 publication Critical patent/EA004895B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/005—Coating of tablets or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/007—Marking tablets or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/10—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/02—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
    • B30B11/08—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds carried by a turntable
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/02—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
    • B30B11/14—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds on a movable carrier other than a turntable or a rotating drum
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B15/00—Details of, or accessories for, presses; Auxiliary measures in connection with pressing
    • B30B15/06—Platens or press rams
    • B30B15/065—Press rams
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03H—HOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H1/00—Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
    • G03H1/02—Details of features involved during the holographic process; Replication of holograms without interference recording
    • G03H1/024—Hologram nature or properties
    • G03H1/0244—Surface relief holograms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J2205/00—General identification or selection means
    • A61J2205/20—Colour codes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J2205/00—General identification or selection means
    • A61J2205/40—General identification or selection means by shape or form, e.g. by using shape recognition
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03H—HOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H1/00—Holographic processes or apparatus using light, infrared or ultraviolet waves for obtaining holograms or for obtaining an image from them; Details peculiar thereto
    • G03H1/0005—Adaptation of holography to specific applications
    • G03H2001/0055—Adaptation of holography to specific applications in advertising or decorative art
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03H—HOLOGRAPHIC PROCESSES OR APPARATUS
    • G03H2270/00—Substrate bearing the hologram
    • G03H2270/10—Composition

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mechanical Engineering (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Preparation (AREA)
  • Holo Graphy (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Diffracting Gratings Or Hologram Optical Elements (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

Съедобное изделие, в частности стандартная дозовая форма фармацевтически активного вещества, включает слой материала, на котором может быть отформован и сохранен микрорельеф с высоким разрешением, способный передавать информацию. Микрорельеф может быть получен методом термоформования, и предпочтительно его формуют из водного раствора гидроксипропилметилцеллюлозы и/или гидроксипропилцеллюлозы с пластификатором и красителем. В зависимости от конкретного использования изделия могут применяться другие добавки, в частности укрепляющие, поверхностно-активные и клеящие агенты. Материалы выбирают и вводят в состав в таком соотношении, при котором обеспечивается возможность контроля изменения интенсивности или цвета визуального изображения или эффекта, создаваемого рельефом, для указания воздействия недопустимой температуры или влажности. Дозовая форма может быть выполнена в виде самого слоя с фармацевтическим агентом, содержащего рельеф. В предпочтительном варианте указанный слой является наружным покрытием ядра, содержащего фармацевтически активное вещество. Таблетки с нанесенным покрытием имеют конфигурацию, препятствующую их сдваиванию. Для получения таких дозовых форм ядро с нанесенным покрытием перемещают согласованно с гибким формующим элементом или передаточной пластиной, предназначенной для горячего формования микрорельефа на наружном слое дозовой формы с последующим охлаждением и отделением этой пластины от покрытия.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200200089A 1999-08-05 2000-08-03 Съедобные изделия с голографическим рисунком, в частности фармацевтические препараты, и способы и устройство для их получения EA004895B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14740699P 1999-08-05 1999-08-05
PCT/US2000/021149 WO2001010464A1 (en) 1999-08-05 2000-08-03 Edible holographic products, particularly pharmaceuticals and methods and apparatus for producing same

Publications (2)

Publication Number Publication Date
EA200200089A1 true EA200200089A1 (ru) 2002-08-29
EA004895B1 EA004895B1 (ru) 2004-08-26

Family

ID=22521454

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200200089A EA004895B1 (ru) 1999-08-05 2000-08-03 Съедобные изделия с голографическим рисунком, в частности фармацевтические препараты, и способы и устройство для их получения

Country Status (37)

Country Link
US (2) US7083805B2 (ru)
EP (1) EP1206280A4 (ru)
JP (1) JP2003506415A (ru)
KR (1) KR20020059358A (ru)
CN (2) CN1216643C (ru)
AP (1) AP2002002434A0 (ru)
AR (1) AR028158A1 (ru)
AU (1) AU772936C (ru)
BG (1) BG106424A (ru)
BR (1) BR0012920A (ru)
CA (1) CA2378591A1 (ru)
CO (1) CO5200853A1 (ru)
CR (1) CR6572A (ru)
CZ (1) CZ2002207A3 (ru)
EA (1) EA004895B1 (ru)
EE (1) EE200200058A (ru)
GE (1) GEP20043376B (ru)
GT (1) GT200000126A (ru)
HK (1) HK1048437A1 (ru)
HN (1) HN2000000165A (ru)
HR (1) HRP20020199A2 (ru)
HU (1) HUP0203796A2 (ru)
IL (1) IL147943A0 (ru)
IS (1) IS6244A (ru)
MX (1) MXPA02001176A (ru)
NO (1) NO20020545L (ru)
NZ (1) NZ516741A (ru)
OA (1) OA12044A (ru)
PA (1) PA8499001A1 (ru)
PE (1) PE20010664A1 (ru)
PL (1) PL353615A1 (ru)
SK (1) SK1792002A3 (ru)
TR (1) TR200200309T2 (ru)
UY (1) UY26270A1 (ru)
WO (1) WO2001010464A1 (ru)
YU (1) YU7602A (ru)
ZA (1) ZA200200605B (ru)

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