EA201400563A1 - Способ получения хинолинкарбоновой кислоты - Google Patents
Способ получения хинолинкарбоновой кислотыInfo
- Publication number
- EA201400563A1 EA201400563A1 EA201400563A EA201400563A EA201400563A1 EA 201400563 A1 EA201400563 A1 EA 201400563A1 EA 201400563 A EA201400563 A EA 201400563A EA 201400563 A EA201400563 A EA 201400563A EA 201400563 A1 EA201400563 A1 EA 201400563A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- formula
- acid
- chlorine
- alkyl
- optionally substituted
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title 1
- 150000001735 carboxylic acids Chemical class 0.000 abstract 2
- 239000000460 chlorine Chemical group 0.000 abstract 2
- 229910052801 chlorine Chemical group 0.000 abstract 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000000729 antidote Substances 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000004009 herbicide Substances 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- -1 quinolinecarboxylic acid compound Chemical class 0.000 abstract 1
- 150000003248 quinolines Chemical class 0.000 abstract 1
- 239000012266 salt solution Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/32—Ingredients for reducing the noxious effect of the active substances to organisms other than pests, e.g. toxicity reducing compositions, self-destructing compositions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
- C07D215/10—Quaternary compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
- C07D215/28—Alcohols; Ethers thereof with halogen atoms or nitro radicals in positions 5, 6 or 7
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Agronomy & Crop Science (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Quinoline Compounds (AREA)
Abstract
Изобретение предусматривает способ получения карбоновой кислоты формулы (IV) (которая пригодна в качестве антидота для гербицидов)где Rпредставляет собой водород или хлор; включающий следующие этапы: (i) подвергание соединения формулы (V)где Rопределен выше; a Rпредставляет собой C-C-алкил; C-С-алкокси-C-C-алкил; необязательно замещенный фенил или необязательно замещенный бензил; гидролизу в кислотных условиях с получением раствора соли хинолиния; (ii) добавление основания к раствору, полученному на этапе (i), с получением свободной карбоновой кислоты (IV). Изобретение также предусматривает твердую (например, в форме частиц) форму одного соединения хинолинкарбоновой кислоты формулы (IV), причем согласно определению Rпредставляет собой хлор; и новые промежуточные продукты, используемые в описанном выше способе.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1119690.4A GB201119690D0 (en) | 2011-11-14 | 2011-11-14 | Process for the preparation of compounds |
| PCT/EP2012/072636 WO2013072376A1 (en) | 2011-11-14 | 2012-11-14 | Process for the preparation of a quinoline carboxylic acid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA201400563A1 true EA201400563A1 (ru) | 2014-11-28 |
| EA029206B1 EA029206B1 (ru) | 2018-02-28 |
Family
ID=45444156
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201400563A EA029206B1 (ru) | 2011-11-14 | 2012-11-14 | Способ получения хинолинкарбоновой кислоты |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US9193686B2 (ru) |
| EP (1) | EP2780323B1 (ru) |
| JP (1) | JP6333177B2 (ru) |
| CN (1) | CN103930402B (ru) |
| AU (1) | AU2012338853B2 (ru) |
| CA (1) | CA2856203C (ru) |
| DK (1) | DK2780323T3 (ru) |
| EA (1) | EA029206B1 (ru) |
| ES (1) | ES2640527T3 (ru) |
| GB (1) | GB201119690D0 (ru) |
| PL (1) | PL2780323T3 (ru) |
| UA (1) | UA113067C2 (ru) |
| WO (1) | WO2013072376A1 (ru) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015191498A1 (en) * | 2014-06-10 | 2015-12-17 | Dow Agrosciences Llc | Solid herbicidal compositions containing a safener |
| CN113135851B (zh) * | 2021-04-26 | 2024-10-01 | 甘肃联凯生物科技有限公司 | 一种解毒喹的合成方法 |
| GB2626177A (en) * | 2023-01-13 | 2024-07-17 | Rotam Agrochem Int Co Ltd | Herbicidal composition comprising pinoxaden |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH408006A (de) * | 1962-05-11 | 1966-02-28 | Geigy Ag J R | Verfahren zur Herstellung von Chinolyl-(8)-oxyessigsäurederivaten |
| ATE103902T1 (de) * | 1982-05-07 | 1994-04-15 | Ciba Geigy Ag | Verwendung von chinolinderivaten zum schuetzen von kulturpflanzen. |
| EP0191736B1 (de) * | 1985-02-14 | 1991-07-17 | Ciba-Geigy Ag | Verwendung von Chinolinderivaten zum Schützen von Kulturpflanzen |
| EP0551650B1 (de) * | 1991-12-31 | 1999-10-13 | Hoechst Schering AgrEvo GmbH | Kombinationen aus Herbiziden und pflanzenschützenden Stoffen |
| KR100616040B1 (ko) * | 1998-06-16 | 2006-08-28 | 바스프 악티엔게젤샤프트 | 상승 효과를 갖는 제초제 혼합물 |
| AU780534B2 (en) * | 2000-06-28 | 2005-03-24 | Syngenta Participations Ag | Process for the preparation of quinoline derivatives |
| US7319041B2 (en) * | 2002-09-27 | 2008-01-15 | Siemens Medical Solutions Diagnostic | Applications of acridinium compounds and derivatives in homogeneous assays |
| GB0714451D0 (en) * | 2007-07-24 | 2007-09-05 | Syngenta Participations Ag | Herbicidal compositions |
-
2011
- 2011-11-14 GB GBGB1119690.4A patent/GB201119690D0/en not_active Ceased
-
2012
- 2012-11-14 AU AU2012338853A patent/AU2012338853B2/en active Active
- 2012-11-14 EA EA201400563A patent/EA029206B1/ru not_active IP Right Cessation
- 2012-11-14 EP EP12784277.1A patent/EP2780323B1/en active Active
- 2012-11-14 WO PCT/EP2012/072636 patent/WO2013072376A1/en not_active Ceased
- 2012-11-14 JP JP2014540519A patent/JP6333177B2/ja active Active
- 2012-11-14 UA UAA201406454A patent/UA113067C2/uk unknown
- 2012-11-14 CN CN201280055755.0A patent/CN103930402B/zh active Active
- 2012-11-14 US US14/357,254 patent/US9193686B2/en active Active
- 2012-11-14 PL PL12784277T patent/PL2780323T3/pl unknown
- 2012-11-14 CA CA2856203A patent/CA2856203C/en active Active
- 2012-11-14 DK DK12784277.1T patent/DK2780323T3/en active
- 2012-11-14 ES ES12784277.1T patent/ES2640527T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| UA113067C2 (xx) | 2016-12-12 |
| EP2780323B1 (en) | 2017-07-05 |
| ES2640527T3 (es) | 2017-11-03 |
| CN103930402A (zh) | 2014-07-16 |
| US20140323302A1 (en) | 2014-10-30 |
| JP6333177B2 (ja) | 2018-05-30 |
| US9193686B2 (en) | 2015-11-24 |
| DK2780323T3 (en) | 2017-09-18 |
| PL2780323T3 (pl) | 2017-11-30 |
| WO2013072376A1 (en) | 2013-05-23 |
| CA2856203C (en) | 2020-03-24 |
| AU2012338853A1 (en) | 2014-05-29 |
| CA2856203A1 (en) | 2013-05-23 |
| EA029206B1 (ru) | 2018-02-28 |
| GB201119690D0 (en) | 2011-12-28 |
| AU2012338853B2 (en) | 2017-04-13 |
| CN103930402B (zh) | 2016-12-07 |
| EP2780323A1 (en) | 2014-09-24 |
| JP2015501790A (ja) | 2015-01-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ KZ KG TJ TM |