EA201400563A1 - Способ получения хинолинкарбоновой кислоты - Google Patents

Способ получения хинолинкарбоновой кислоты

Info

Publication number
EA201400563A1
EA201400563A1 EA201400563A EA201400563A EA201400563A1 EA 201400563 A1 EA201400563 A1 EA 201400563A1 EA 201400563 A EA201400563 A EA 201400563A EA 201400563 A EA201400563 A EA 201400563A EA 201400563 A1 EA201400563 A1 EA 201400563A1
Authority
EA
Eurasian Patent Office
Prior art keywords
formula
acid
chlorine
alkyl
optionally substituted
Prior art date
Application number
EA201400563A
Other languages
English (en)
Other versions
EA029206B1 (ru
Inventor
Жан-Жак Роже Голлю
Арно Жан Альбер Гайе
Original Assignee
Зингента Партисипейшнс Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Зингента Партисипейшнс Аг filed Critical Зингента Партисипейшнс Аг
Publication of EA201400563A1 publication Critical patent/EA201400563A1/ru
Publication of EA029206B1 publication Critical patent/EA029206B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/32—Ingredients for reducing the noxious effect of the active substances to organisms other than pests, e.g. toxicity reducing compositions, self-destructing compositions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
    • C07D215/10—Quaternary compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • C07D215/28—Alcohols; Ethers thereof with halogen atoms or nitro radicals in positions 5, 6 or 7
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Quinoline Compounds (AREA)

Abstract

Изобретение предусматривает способ получения карбоновой кислоты формулы (IV) (которая пригодна в качестве антидота для гербицидов)где Rпредставляет собой водород или хлор; включающий следующие этапы: (i) подвергание соединения формулы (V)где Rопределен выше; a Rпредставляет собой C-C-алкил; C-С-алкокси-C-C-алкил; необязательно замещенный фенил или необязательно замещенный бензил; гидролизу в кислотных условиях с получением раствора соли хинолиния; (ii) добавление основания к раствору, полученному на этапе (i), с получением свободной карбоновой кислоты (IV). Изобретение также предусматривает твердую (например, в форме частиц) форму одного соединения хинолинкарбоновой кислоты формулы (IV), причем согласно определению Rпредставляет собой хлор; и новые промежуточные продукты, используемые в описанном выше способе.
EA201400563A 2011-11-14 2012-11-14 Способ получения хинолинкарбоновой кислоты EA029206B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1119690.4A GB201119690D0 (en) 2011-11-14 2011-11-14 Process for the preparation of compounds
PCT/EP2012/072636 WO2013072376A1 (en) 2011-11-14 2012-11-14 Process for the preparation of a quinoline carboxylic acid

Publications (2)

Publication Number Publication Date
EA201400563A1 true EA201400563A1 (ru) 2014-11-28
EA029206B1 EA029206B1 (ru) 2018-02-28

Family

ID=45444156

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201400563A EA029206B1 (ru) 2011-11-14 2012-11-14 Способ получения хинолинкарбоновой кислоты

Country Status (13)

Country Link
US (1) US9193686B2 (ru)
EP (1) EP2780323B1 (ru)
JP (1) JP6333177B2 (ru)
CN (1) CN103930402B (ru)
AU (1) AU2012338853B2 (ru)
CA (1) CA2856203C (ru)
DK (1) DK2780323T3 (ru)
EA (1) EA029206B1 (ru)
ES (1) ES2640527T3 (ru)
GB (1) GB201119690D0 (ru)
PL (1) PL2780323T3 (ru)
UA (1) UA113067C2 (ru)
WO (1) WO2013072376A1 (ru)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA121215C2 (uk) 2014-06-10 2020-04-27 Дау Аґросаєнсиз Елелсі Тверді гербіцидні композиції, які містять антидот
CN113135851B (zh) * 2021-04-26 2024-10-01 甘肃联凯生物科技有限公司 一种解毒喹的合成方法
GB2626177A (en) * 2023-01-13 2024-07-17 Rotam Agrochem Int Co Ltd Herbicidal composition comprising pinoxaden

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH408006A (de) * 1962-05-11 1966-02-28 Geigy Ag J R Verfahren zur Herstellung von Chinolyl-(8)-oxyessigsäurederivaten
ATE103902T1 (de) 1982-05-07 1994-04-15 Ciba Geigy Ag Verwendung von chinolinderivaten zum schuetzen von kulturpflanzen.
EP0191736B1 (de) * 1985-02-14 1991-07-17 Ciba-Geigy Ag Verwendung von Chinolinderivaten zum Schützen von Kulturpflanzen
DE59209757D1 (de) * 1991-12-31 1999-11-18 Hoechst Ag Kombinationen aus Herbiziden und pflanzenschützenden Stoffen
IL139905A (en) * 1998-06-16 2005-09-25 Basf Ag Herbicidal mixtures having a synergistic effect
BR0112064B1 (pt) * 2000-06-28 2012-12-25 processo para a preparaÇço de derivados da quinolina.
US7319041B2 (en) * 2002-09-27 2008-01-15 Siemens Medical Solutions Diagnostic Applications of acridinium compounds and derivatives in homogeneous assays
GB0714451D0 (en) * 2007-07-24 2007-09-05 Syngenta Participations Ag Herbicidal compositions

Also Published As

Publication number Publication date
AU2012338853B2 (en) 2017-04-13
UA113067C2 (xx) 2016-12-12
CA2856203A1 (en) 2013-05-23
EP2780323A1 (en) 2014-09-24
US9193686B2 (en) 2015-11-24
WO2013072376A1 (en) 2013-05-23
EA029206B1 (ru) 2018-02-28
PL2780323T3 (pl) 2017-11-30
JP2015501790A (ja) 2015-01-19
CN103930402B (zh) 2016-12-07
DK2780323T3 (en) 2017-09-18
JP6333177B2 (ja) 2018-05-30
GB201119690D0 (en) 2011-12-28
ES2640527T3 (es) 2017-11-03
CA2856203C (en) 2020-03-24
EP2780323B1 (en) 2017-07-05
AU2012338853A1 (en) 2014-05-29
US20140323302A1 (en) 2014-10-30
CN103930402A (zh) 2014-07-16

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