EA201891712A2 - Молекулы нуклеиновых кислот гриппа и вакцины, изготовленные из них - Google Patents

Молекулы нуклеиновых кислот гриппа и вакцины, изготовленные из них

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EA201891712A2
EA201891712A2 EA201891712A EA201891712A EA201891712A2 EA 201891712 A2 EA201891712 A2 EA 201891712A2 EA 201891712 A EA201891712 A EA 201891712A EA 201891712 A EA201891712 A EA 201891712A EA 201891712 A2 EA201891712 A2 EA 201891712A2
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Prior art keywords
influenza
nucleic acid
acid molecules
vaccines produced
vaccines
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EA201891712A
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English (en)
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EA201891712A3 (ru
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Дэвид Б. Уэйнер
Цзянь Янь
Мэттью П. Морроу
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Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания
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Application filed by Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания filed Critical Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания
Publication of EA201891712A2 publication Critical patent/EA201891712A2/ru
Publication of EA201891712A3 publication Critical patent/EA201891712A3/ru

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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P31/12—Antivirals
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    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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    • C12N2760/16011—Orthomyxoviridae
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Abstract

В настоящей заявке представлены последовательности нуклеиновых кислот, которые кодируют новые консенсусные аминокислотные последовательности HA гемагглютинина, а также генетические конструкции/векторы и вакцины, экспрессирующие последовательности. Также в настоящем документе представлены способы генерирования иммунного ответа против одного или более серотипа вируса гриппа A, с использованием представленных вакцин.
EA201891712A 2010-01-26 2011-01-26 Молекулы нуклеиновых кислот гриппа и вакцины, изготовленные из них EA201891712A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12/694,238 US8298820B2 (en) 2010-01-26 2010-01-26 Influenza nucleic acid molecules and vaccines made therefrom

Publications (2)

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EA201891712A2 true EA201891712A2 (ru) 2019-01-31
EA201891712A3 EA201891712A3 (ru) 2019-05-31

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EA201891712A EA201891712A3 (ru) 2010-01-26 2011-01-26 Молекулы нуклеиновых кислот гриппа и вакцины, изготовленные из них
EA201201025A EA031321B1 (ru) 2010-01-26 2011-01-26 Нуклеиновые кислоты, кодирующие белки вируса гриппа, композиции на их основе и способы профилактики и лечения

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EA201201025A EA031321B1 (ru) 2010-01-26 2011-01-26 Нуклеиновые кислоты, кодирующие белки вируса гриппа, композиции на их основе и способы профилактики и лечения

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US (4) US8298820B2 (ru)
EP (2) EP3173103A1 (ru)
JP (2) JP5992337B2 (ru)
KR (2) KR101912330B1 (ru)
CN (2) CN102753200B (ru)
AU (1) AU2011209626B2 (ru)
BR (1) BR112012018587A2 (ru)
CA (1) CA2786901A1 (ru)
EA (2) EA201891712A3 (ru)
ES (1) ES2600890T3 (ru)
HK (1) HK1249139A1 (ru)
IN (1) IN2012DN06289A (ru)
MX (3) MX357191B (ru)
WO (1) WO2011094358A1 (ru)
ZA (1) ZA201307844B (ru)

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BR112017011556A2 (en) 2014-12-01 2018-03-06 The Trustees Of The University Of Pennsylvania methods for generating a synthetic antibody, preventing or treating a disease, treating a subject of pathogen infection and a subject with cancer, product, nucleic acid molecule, and composition.
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HK1249014A1 (zh) 2015-03-20 2018-10-26 The Trustees Of The University Of Pennsylvania 具有作为佐剂的cd40配体的疫苗
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US20180133307A1 (en) 2018-05-17
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