EA202192575A1 - Соединения dbait в сочетании с ингибиторами киназ для лечения рака - Google Patents

Соединения dbait в сочетании с ингибиторами киназ для лечения рака

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Publication number
EA202192575A1
EA202192575A1 EA202192575A EA202192575A EA202192575A1 EA 202192575 A1 EA202192575 A1 EA 202192575A1 EA 202192575 A EA202192575 A EA 202192575A EA 202192575 A EA202192575 A EA 202192575A EA 202192575 A1 EA202192575 A1 EA 202192575A1
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EA
Eurasian Patent Office
Prior art keywords
dbait
combination
compounds
kinase inhibitors
cancer treatment
Prior art date
Application number
EA202192575A
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English (en)
Inventor
Франсуаза Боно
Жиль Фавр
Оливье Кальвейрак
Original Assignee
Онксео
Инсерм (Энститю Насьональ Де Ля Сантэ Э Де Ля Решерш Медикаль)
Юниверсите Поль Сабатье Тулуз Iii
Энститю Клодиус Рего
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Application filed by Онксео, Инсерм (Энститю Насьональ Де Ля Сантэ Э Де Ля Решерш Медикаль), Юниверсите Поль Сабатье Тулуз Iii, Энститю Клодиус Рего filed Critical Онксео
Publication of EA202192575A1 publication Critical patent/EA202192575A1/ru

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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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    • C12N15/09—Recombinant DNA-technology
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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Abstract

Изобретение относится к комбинации соединения Dbait с ингибитором протеинкиназы для лечения рака.
EA202192575A 2019-03-21 2020-03-19 Соединения dbait в сочетании с ингибиторами киназ для лечения рака EA202192575A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19305349 2019-03-21
PCT/EP2020/057555 WO2020188015A1 (en) 2019-03-21 2020-03-19 A dbait molecule in combination with kinase inhibitor for the treatment of cancer

Publications (1)

Publication Number Publication Date
EA202192575A1 true EA202192575A1 (ru) 2022-01-14

Family

ID=66103004

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202192575A EA202192575A1 (ru) 2019-03-21 2020-03-19 Соединения dbait в сочетании с ингибиторами киназ для лечения рака

Country Status (12)

Country Link
US (1) US20220143049A1 (ru)
EP (1) EP3942045A1 (ru)
JP (1) JP2022526713A (ru)
KR (1) KR20210142154A (ru)
CN (1) CN114364798A (ru)
AU (1) AU2020242287A1 (ru)
BR (1) BR112021018168B1 (ru)
CA (1) CA3129665A1 (ru)
EA (1) EA202192575A1 (ru)
IL (1) IL284856A (ru)
MX (1) MX2021009863A (ru)
WO (1) WO2020188015A1 (ru)

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WO2019175132A1 (en) * 2018-03-13 2019-09-19 Onxeo A dbait molecule against acquired resistance in the treatment of cancer
WO2021148581A1 (en) 2020-01-22 2021-07-29 Onxeo Novel dbait molecule and its use
KR102657354B1 (ko) * 2021-06-08 2024-04-15 한국과학기술원 Syk 저해제를 포함하는 대장암 예방 또는 치료용 병용투여 조성물
WO2023129667A1 (en) 2021-12-30 2023-07-06 Biomea Fusion, Inc. Pyrazine compounds as inhibitors of flt3

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