ECSP003403A - PROTEASE INHIBITORS XI - Google Patents
PROTEASE INHIBITORS XIInfo
- Publication number
- ECSP003403A ECSP003403A ECSP003403A ECSP003403A EC SP003403 A ECSP003403 A EC SP003403A EC SP003403 A ECSP003403 A EC SP003403A EC SP003403 A ECSP003403 A EC SP003403A
- Authority
- EC
- Ecuador
- Prior art keywords
- excessive
- disease
- cartilage
- matrix
- proteases
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención proporciona inhibidores de proteasas de 4-amino-4,5-dihidro-benzo [b] [1,4] dioxocin-3-ona, y sus sales, hidratos y solvatos farmacéuticamente aceptables que inhiben las proteasas, con inclusión de la captesina K, composiciones farmacéuticas de tales compuestos y métodos para tratar enfermedades de pérdida ósea excesiva o degradación excesiva de cartílago o matriz, que incluyen osteoporosis, enfermedad gingival con inclusión de gingivitis y periodontitis, artritis, más especificamente osteoartritis y artritis reumatoide; enfermedad de Paget; hipercalcemia de carácter maligno; y enfermedad metabólica osea, que comprenden inhibir dicha pérdida ósea o degradación excesiva de cartílago o matriz por administración a un paciente que se encuentra en necesidad de ello de un compuesto de la presente invención.The present invention provides inhibitors of 4-amino-4,5-dihydro-benzo [b] [1,4] dioxocin-3-one proteases, and their pharmaceutically acceptable salts, hydrates and solvates that inhibit proteases, including captesin K, pharmaceutical compositions of such compounds, and methods of treating diseases of excessive bone loss or excessive degradation of cartilage or matrix, including osteoporosis, gingival disease including gingivitis and periodontitis, arthritis, more specifically osteoarthritis and rheumatoid arthritis; Paget's disease; malignant hypercalcemia; and bone metabolic disease, which comprises inhibiting said bone loss or excessive cartilage or matrix degradation by administration to a patient in need thereof of a compound of the present invention.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP003403 ECSP003403A (en) | 2000-03-28 | 2000-03-28 | PROTEASE INHIBITORS XI |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP003403 ECSP003403A (en) | 2000-03-28 | 2000-03-28 | PROTEASE INHIBITORS XI |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP003403A true ECSP003403A (en) | 2000-05-25 |
Family
ID=42041033
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP003403 ECSP003403A (en) | 2000-03-28 | 2000-03-28 | PROTEASE INHIBITORS XI |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP003403A (en) |
-
2000
- 2000-03-28 EC ECSP003403 patent/ECSP003403A/en unknown
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