ECSP003478A - SUBSTITUTED POLYCLIC ARYL AND HETEROARIL URACILS USEFUL FOR THE SELECTIVE INHIBITION OF THE COAGULATION WATERFALL - Google Patents
SUBSTITUTED POLYCLIC ARYL AND HETEROARIL URACILS USEFUL FOR THE SELECTIVE INHIBITION OF THE COAGULATION WATERFALLInfo
- Publication number
- ECSP003478A ECSP003478A ECSP003478A ECSP003478A EC SP003478 A ECSP003478 A EC SP003478A EC SP003478 A ECSP003478 A EC SP003478A EC SP003478 A ECSP003478 A EC SP003478A
- Authority
- EC
- Ecuador
- Prior art keywords
- useful
- substituted
- heteroaril
- uracils
- selective inhibition
- Prior art date
Links
- 230000015271 coagulation Effects 0.000 title abstract 2
- 238000005345 coagulation Methods 0.000 title abstract 2
- 230000005764 inhibitory process Effects 0.000 title 1
- ISAKRJDGNUQOIC-UHFFFAOYSA-N Uracil Chemical compound O=C1C=CNC(=O)N1 ISAKRJDGNUQOIC-UHFFFAOYSA-N 0.000 abstract 2
- 239000003146 anticoagulant agent Substances 0.000 abstract 1
- 229940127219 anticoagulant drug Drugs 0.000 abstract 1
- 208000026106 cerebrovascular disease Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000029078 coronary artery disease Diseases 0.000 abstract 1
- 210000004351 coronary vessel Anatomy 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 239000003001 serine protease inhibitor Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 230000001732 thrombotic effect Effects 0.000 abstract 1
- 229940035893 uracil Drugs 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
El invento se relaciona a compuestos de aril policiclico sustituido y uracilos y heteroaril útiles como inhibidores de serinas proteasas de la cascada de coagulación y sus compuestos, composiciones y métodos para la terapia anticoagulante para el tratamiento y prevención de una variedad de condiciones trombóticas incluyendo arteria coronaria y enfermedades cerebrovasculares.The invention relates to substituted polycyclic aryl and uracil and heteroaryl compounds useful as coagulation cascade serine protease inhibitors and their compounds, compositions and methods for anticoagulant therapy for the treatment and prevention of a variety of thrombotic conditions including coronary artery and cerebrovascular diseases.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP003478 ECSP003478A (en) | 2000-05-19 | 2000-05-19 | SUBSTITUTED POLYCLIC ARYL AND HETEROARIL URACILS USEFUL FOR THE SELECTIVE INHIBITION OF THE COAGULATION WATERFALL |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP003478 ECSP003478A (en) | 2000-05-19 | 2000-05-19 | SUBSTITUTED POLYCLIC ARYL AND HETEROARIL URACILS USEFUL FOR THE SELECTIVE INHIBITION OF THE COAGULATION WATERFALL |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP003478A true ECSP003478A (en) | 2000-11-24 |
Family
ID=42041104
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP003478 ECSP003478A (en) | 2000-05-19 | 2000-05-19 | SUBSTITUTED POLYCLIC ARYL AND HETEROARIL URACILS USEFUL FOR THE SELECTIVE INHIBITION OF THE COAGULATION WATERFALL |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP003478A (en) |
-
2000
- 2000-05-19 EC ECSP003478 patent/ECSP003478A/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| UY26154A1 (en) | ARIL AND HETEROARIL REPLACED POLYCYCLIC PYRIDONES USEFUL FOR THE SELECTIVE INHIBITION OF THE COAGULATION WATERFALL | |
| UY26157A1 (en) | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL USEFUL FOR THE SELECTIVE I NHIBITION OF THE COAGULATION WATERFALL | |
| UY26156A1 (en) | ARIL AND HETEROARIL POLYCYCLIC PIRIMIDONES SUBSTITUTED USEFUL FOR THE SELECTIVE INHIBITION OF THE COAGULATION WATERFALL | |
| SV2005001973A (en) | USEFUL KINOLINES IN THE TREATMENT OF CARDIOVASCULAR DISEASES REF. WYTH0090-504 (AM101500) | |
| NO20071078L (en) | Antiviral compounds | |
| NO20070866L (en) | Antiviral compounds. | |
| UY27774A1 (en) | METALOPROTEIN INHIBITORS OF TRIARIL-OXI-ARIL-ESPIROPIRIMIDINA-2,4,6-TRIONA | |
| DK1206474T3 (en) | Sulfonylphenylpyrazole compounds useful as cox-2 inhibitors | |
| PL363168A1 (en) | Cyclopentanols, compositions containing such compounds and methods of treatment | |
| ECSP066424A (en) | DERIVATIVES OF 2,4-DI- (IET) -ARIL-AMINO-PYRIMIDINE AS INHIBITORS OF ZAP-70 AND / OR SYK | |
| SV2004001414A (en) | INHIBITORS OF FACTOR XA AND OTHER SERINE PROTEASES INVOLVED IN THE COAGULATION WATERFALL. PC20535 | |
| EP1446115A4 (en) | CYANOALKYLAMINO DERIVATIVES AS INHIBITORS OF PROTEASE | |
| DE602005014621D1 (en) | 3-A4-HETEROCYCLYL-1,2,3-TRIAZOL-1-YLÜ-N-ARYLBENZAMIDES AS INHIBITORS OF CYTOKIN PRODUCTION FOR THE TREATMENT OF CHRONIC INFLAMMATORY DISEASES | |
| DE602004015810D1 (en) | SUBSTITUTED ISOCHINOLINE DERIVATIVES AND METHOD OF USE | |
| BR0011295A (en) | Aryl and heteroaryl substituted polycyclic pyrazinones useful for selective inhibition of coagulation cascade | |
| EA200801530A1 (en) | ANALOGUES OF ARYLPROPIONAMID, ARYLACRYLAMIDE, ARYLPROPINAMIDE OR ARYLMETHYLMANE AS A FACTOR XIA INHIBITORS | |
| CY1109992T1 (en) | Alpha-aminamide derivatives useful as anti-inflammatory agents | |
| ATE367380T1 (en) | PIPERAZINYLQUINOLINE DERIVATIVES SUITABLE FOR THE TREATMENT OF CNS DISEASES | |
| ATE422201T1 (en) | 4-(HETEROCYCLYL)-BENZENESULFOXIMINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISEASES | |
| DE60316128D1 (en) | N-sulfonylurea APOPTOSIS PROMOTERS | |
| PT1268463E (en) | 4-PYRONES SUBSTITUTED WITH USUAL POLYCYCLIC AERIAL AND HETEROARYL FOR THE SELECTIVE INHIBITION OF COAGULACAO CASCADE | |
| ECSP056106A (en) | NEW PHOSPHONIC ACID COMPOUNDS AS INHIBITORS OF SERINA PROTEASAS | |
| ECSP003478A (en) | SUBSTITUTED POLYCLIC ARYL AND HETEROARIL URACILS USEFUL FOR THE SELECTIVE INHIBITION OF THE COAGULATION WATERFALL | |
| MY132033A (en) | New mandelic acid derivatives and their use as thrombin inhibitors | |
| ECSP003476A (en) | SUBSTITUTED POLYCLIC ARYL AND HETEROARIL PIRIMIDINONES USEFUL FOR THE SELECTIVE INHIBITION OF THE COAGULATION WATERFALL |