ECSP014065A - Una composicion farmaceutica y procedimiento de tratamiento de enfermedades de disfuncion cognitiva en un mamifero - Google Patents
Una composicion farmaceutica y procedimiento de tratamiento de enfermedades de disfuncion cognitiva en un mamiferoInfo
- Publication number
- ECSP014065A ECSP014065A EC2001004065A ECSP014065A ECSP014065A EC SP014065 A ECSP014065 A EC SP014065A EC 2001004065 A EC2001004065 A EC 2001004065A EC SP014065 A ECSP014065 A EC SP014065A EC SP014065 A ECSP014065 A EC SP014065A
- Authority
- EC
- Ecuador
- Prior art keywords
- cognitive dysfunction
- pharmaceutically acceptable
- disease
- agonist
- mammal
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Psychology (AREA)
- AIDS & HIV (AREA)
- Heart & Thoracic Surgery (AREA)
- Tropical Medicine & Parasitology (AREA)
- Cardiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Hospice & Palliative Care (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Una composición farmacéutica y un procedimiento de tratamiento de enfermedades de disfunción cognitiva en un mamífero, que comprende la administración de un agonista parcial del receptor de nicotina o una sal farmacéuticamente aceptable del mismo; y un inhibidor de acetilcolinesterasa, un inhibidor de butilcolinesterasas, un agente estrogénico, un modulador selectivo del receptor de estrógenos o un agonista muscarínico, o una sal farmacéuticamente aceptable de los mismos; y un vehículo farmacéuticamente aceptable. El agonista parcial del receptor de nicotina y el inhibidor de acetilcolinesterasa, el inhibidor de butilcolinesterasa, el estrógeno, el modulador selectivo del receptor de estrógenos o el agonista muscarínico están presente en cantidades que hacen a la composición eficaz en la potenciación de la cognición o en el tratamiento de enfermedades de disfunción cognitiva que incluyen, pero sin limitación, la Enfermedad de Alzheimer, deterioro cognitivo leve, disminución cognitiva relacionada con la edad, demencia vascular, demencia por enfermedad de Parkinson. Enfermedad de Huntington, Apoplejía, TBI, demencia asociada con el SIDA y esquizofrenia. También se describe el procedimiento de uso de estas composiciones.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20279900P | 2000-05-09 | 2000-05-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP014065A true ECSP014065A (es) | 2003-01-13 |
Family
ID=22751325
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2001004065A ECSP014065A (es) | 2000-05-09 | 2001-05-08 | Una composicion farmaceutica y procedimiento de tratamiento de enfermedades de disfuncion cognitiva en un mamifero |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US20010036949A1 (es) |
| EP (1) | EP1280554A2 (es) |
| JP (1) | JP2003532670A (es) |
| AR (1) | AR028426A1 (es) |
| AU (1) | AU2001248699A1 (es) |
| BR (1) | BR0110487A (es) |
| CA (1) | CA2409720A1 (es) |
| EC (1) | ECSP014065A (es) |
| GT (1) | GT200100075A (es) |
| MX (1) | MXPA02011051A (es) |
| PA (1) | PA8516701A1 (es) |
| PE (1) | PE20011256A1 (es) |
| PY (1) | PY0108909A (es) |
| SV (1) | SV2002000440A (es) |
| TN (1) | TNSN01068A1 (es) |
| UY (1) | UY26693A1 (es) |
| WO (1) | WO2001085145A2 (es) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050063998A1 (en) * | 1999-10-26 | 2005-03-24 | Francois Marc Karel Jozef | Oral solution containing galantamine and a sweetening agent |
| US20030153598A1 (en) * | 2000-07-25 | 2003-08-14 | Raymond Pratt | Methods for treating Parkinson's disease with cholinesterase inhibitors |
| US20060183776A9 (en) * | 2000-03-03 | 2006-08-17 | Eisai Co., Ltd. | Liquid dosage formulations of donepezil |
| EP2133078A1 (en) | 2000-03-03 | 2009-12-16 | Eisai R&D Management Co., Ltd. | Use of a cholinesterase inhibitor for the treatment of dementia and cognitive impairments |
| MXPA03009527A (es) * | 2001-04-20 | 2004-02-12 | Pfizer Prod Inc | PROCEDIMIENTO PARA LA PREPARACIoN DE INDENOS 1,3-SUSTITUIDOS Y COMPUESTOS AZAPOLICICLICOS CONDENSADOS CON ARILO. |
| AU2756602A (en) * | 2001-04-25 | 2002-10-31 | Pfizer Products Inc. | Methods and kits for treating depression or preventing deterioration of cognitive function |
| WO2003017994A1 (en) * | 2001-08-31 | 2003-03-06 | Neurochem (International) Limited | Amidine derivatives for treating amyloidosis |
| US20040092427A1 (en) * | 2002-09-25 | 2004-05-13 | Anil Gulati | Method and composition for treating alzheimer's disease and dementias of vascular origin |
| US8030300B2 (en) * | 2003-06-10 | 2011-10-04 | Georgetown University | Ligands for nicotinic acetylcholine receptors, and methods of making and using them |
| US8299062B2 (en) * | 2003-09-17 | 2012-10-30 | Franklin Volvovitz | Pharmaceutical compositions and methods for preventing, treating, or reversing neuronal dysfunction |
| KR20140015122A (ko) | 2003-10-01 | 2014-02-06 | 아돌로 코포레이션 | 스피로시클릭 헤테로시클릭 유도체 및 이의 사용 방법 |
| US20060019938A1 (en) * | 2003-12-31 | 2006-01-26 | Beer Tomasz M | Estrogen administration for treating male cognitive dysfunction or improving male cognitive function |
| US7262223B2 (en) * | 2004-01-23 | 2007-08-28 | Neurochem (International) Limited | Amidine derivatives for treating amyloidosis |
| US20050182044A1 (en) * | 2004-02-17 | 2005-08-18 | Bruinsma Gosse B. | Combinatorial therapy with an acetylcholinesterase inhibitor and (3aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3,-b]indol-5-yl phenylcarbamate |
| CA2566204A1 (en) * | 2004-05-14 | 2005-12-01 | The Johns Hopkins University | Method for improving cognitive function by co-administration of a gabab receptor antagonist and an acetylcholinesterase inhibitor |
| AU2005247948A1 (en) * | 2004-05-27 | 2005-12-08 | Migenix Corp. | 2-substituted 17-imino estrogen compounds for cytoprotection |
| WO2007025177A2 (en) * | 2005-08-26 | 2007-03-01 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
| EP2258359A3 (en) * | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation with sabcomelin |
| US7576207B2 (en) | 2006-04-06 | 2009-08-18 | Adolor Corporation | Spirocyclic heterocyclic derivatives and methods of their use |
| GB0607952D0 (en) * | 2006-04-21 | 2006-05-31 | Minster Res Ltd | Novel treatment |
| GB0607946D0 (en) * | 2006-04-21 | 2006-05-31 | Minster Res The Ltd | Mono and combination therapy |
| MX2009002715A (es) | 2006-09-12 | 2009-08-12 | Adolor Corp | Metodos para mejorar la funcion cognoscitiva. |
| US8278345B2 (en) | 2006-11-09 | 2012-10-02 | Probiodrug Ag | Inhibitors of glutaminyl cyclase |
| US9126987B2 (en) | 2006-11-30 | 2015-09-08 | Probiodrug Ag | Inhibitors of glutaminyl cyclase |
| JP5930573B2 (ja) | 2007-03-01 | 2016-06-15 | プロビオドルグ エージー | グルタミニルシクラーゼ阻害剤の新規使用 |
| JP5667440B2 (ja) | 2007-04-18 | 2015-02-12 | プロビオドルグ エージー | グルタミニルシクラーゼ阻害剤としてのチオ尿素誘導体 |
| FR2931677B1 (fr) * | 2008-06-02 | 2010-08-20 | Sanofi Aventis | Association d'un agoniste partiel des recepteurs nicotiniques et d'un inhibiteur d'acetylcholinesterase, composition la contenant et son utilisation dans le traitement des troubles cognitifs |
| PL2475428T3 (pl) | 2009-09-11 | 2015-12-31 | Probiodrug Ag | Pochodne heterocykliczne jako inhibitory cyklazy glutaminowej |
| EA037187B1 (ru) | 2010-02-09 | 2021-02-17 | Дзе Джонс Хопкинс Юниверсити | Способ и композиция для лечения когнитивного расстройства |
| EP2542549B1 (en) | 2010-03-03 | 2016-05-11 | Probiodrug AG | Inhibitors of glutaminyl cyclase |
| US8269019B2 (en) | 2010-03-10 | 2012-09-18 | Probiodrug Ag | Inhibitors |
| US8541596B2 (en) | 2010-04-21 | 2013-09-24 | Probiodrug Ag | Inhibitors |
| US8349376B1 (en) | 2011-03-08 | 2013-01-08 | Bezzek Mark S | Anti-dementia regimen |
| US8846061B1 (en) | 2011-03-08 | 2014-09-30 | Mark S. Bezzek | Multivitamin-mineral regimens for longevity and wellness |
| US8530670B2 (en) | 2011-03-16 | 2013-09-10 | Probiodrug Ag | Inhibitors |
| US20150031655A1 (en) * | 2011-04-15 | 2015-01-29 | University Of North Dakota | Combination of liver x receptor modulator and estrogen receptor modulator for the treatment of age-related diseases |
| WO2014078568A1 (en) | 2012-11-14 | 2014-05-22 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
| US10806717B2 (en) | 2013-03-15 | 2020-10-20 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
| US11160785B2 (en) | 2013-03-15 | 2021-11-02 | Agenebio Inc. | Methods and compositions for improving cognitive function |
| MX384391B (es) | 2015-05-22 | 2025-03-14 | Agenebio Inc | Composiciones farmacéuticas de levetiracetam de liberación extendida. |
| ES2812698T3 (es) | 2017-09-29 | 2021-03-18 | Probiodrug Ag | Inhibidores de glutaminil ciclasa |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6218383B1 (en) * | 1998-08-07 | 2001-04-17 | Targacept, Inc. | Pharmaceutical compositions for the prevention and treatment of central nervous system disorders |
-
2001
- 2001-01-16 US US09/760,966 patent/US20010036949A1/en not_active Abandoned
- 2001-04-23 PY PY200100108909A patent/PY0108909A/es unknown
- 2001-04-24 WO PCT/IB2001/000681 patent/WO2001085145A2/en not_active Ceased
- 2001-04-24 BR BR0110487-0A patent/BR0110487A/pt not_active IP Right Cessation
- 2001-04-24 MX MXPA02011051A patent/MXPA02011051A/es unknown
- 2001-04-24 JP JP2001581799A patent/JP2003532670A/ja active Pending
- 2001-04-24 EP EP01921733A patent/EP1280554A2/en not_active Withdrawn
- 2001-04-24 CA CA002409720A patent/CA2409720A1/en not_active Abandoned
- 2001-04-24 AU AU2001248699A patent/AU2001248699A1/en not_active Abandoned
- 2001-05-04 GT GT200100075A patent/GT200100075A/es unknown
- 2001-05-07 UY UY26693A patent/UY26693A1/es not_active Application Discontinuation
- 2001-05-08 SV SV2001000440A patent/SV2002000440A/es not_active Application Discontinuation
- 2001-05-08 AR ARP010102169A patent/AR028426A1/es unknown
- 2001-05-08 TN TNTNSN01068A patent/TNSN01068A1/fr unknown
- 2001-05-08 EC EC2001004065A patent/ECSP014065A/es unknown
- 2001-05-08 PE PE2001000412A patent/PE20011256A1/es not_active Application Discontinuation
- 2001-05-09 PA PA20018516701A patent/PA8516701A1/es unknown
-
2003
- 2003-01-21 US US10/347,955 patent/US20030130303A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1280554A2 (en) | 2003-02-05 |
| AR028426A1 (es) | 2003-05-07 |
| MXPA02011051A (es) | 2003-03-10 |
| CA2409720A1 (en) | 2001-11-15 |
| BR0110487A (pt) | 2003-04-01 |
| TNSN01068A1 (fr) | 2005-11-10 |
| SV2002000440A (es) | 2002-10-24 |
| US20030130303A1 (en) | 2003-07-10 |
| PE20011256A1 (es) | 2001-12-29 |
| GT200100075A (es) | 2001-12-31 |
| UY26693A1 (es) | 2001-12-28 |
| US20010036949A1 (en) | 2001-11-01 |
| JP2003532670A (ja) | 2003-11-05 |
| WO2001085145A2 (en) | 2001-11-15 |
| WO2001085145A3 (en) | 2002-06-13 |
| WO2001085145A8 (en) | 2001-12-13 |
| PY0108909A (es) | 2003-11-03 |
| AU2001248699A1 (en) | 2001-11-20 |
| PA8516701A1 (es) | 2002-09-17 |
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