ECSP055780A - Derivados de indol utiles para el tratamiento de enfermedades - Google Patents

Derivados de indol utiles para el tratamiento de enfermedades

Info

Publication number
ECSP055780A
ECSP055780A EC2005005780A ECSP055780A ECSP055780A EC SP055780 A ECSP055780 A EC SP055780A EC 2005005780 A EC2005005780 A EC 2005005780A EC SP055780 A ECSP055780 A EC SP055780A EC SP055780 A ECSP055780 A EC SP055780A
Authority
EC
Ecuador
Prior art keywords
diseases
treatment
derivatives useful
indol derivatives
disorders
Prior art date
Application number
EC2005005780A
Other languages
English (en)
Inventor
Mark Edward Bunnage
Alan Daniel Brown
Justin Stephen Bryans
Paul Alan Glossop
Charlotte Alice Louise Lane
Russell Andrew Lewthwaite
Simon John Mantell
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP20020292513 external-priority patent/EP1407769A1/en
Priority claimed from EP03290069A external-priority patent/EP1440966A1/en
Application filed by Pfizer filed Critical Pfizer
Publication of ECSP055780A publication Critical patent/ECSP055780A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

La invención se refiere a derivados de indol y a procedimientos para la preparación de intermedios usados en la preparación de composiciones que los contienen y el uso de dichos derivados. Los derivados de indol según la presente invención son útiles en numerosas enfermedades, trastornos y afecciones, en particular enfermedades, trastornos y afecciones inflamatorias, alérgicas y respiratorias.
EC2005005780A 2002-10-11 2005-05-05 Derivados de indol utiles para el tratamiento de enfermedades ECSP055780A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20020292513 EP1407769A1 (en) 2002-10-11 2002-10-11 Indole derivatives as beta-2 agonists
EP03290069A EP1440966A1 (en) 2003-01-10 2003-01-10 Indole derivatives useful for the treatment of diseases

Publications (1)

Publication Number Publication Date
ECSP055780A true ECSP055780A (es) 2005-08-11

Family

ID=32095049

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2005005780A ECSP055780A (es) 2002-10-11 2005-05-05 Derivados de indol utiles para el tratamiento de enfermedades

Country Status (25)

Country Link
EP (1) EP1556034B1 (es)
JP (1) JP4490911B2 (es)
KR (1) KR20050047552A (es)
AP (1) AP2005003283A0 (es)
AR (1) AR041566A1 (es)
AT (1) ATE392206T1 (es)
AU (1) AU2003269316A1 (es)
BR (1) BR0315234A (es)
CA (1) CA2499314C (es)
CO (1) CO5550421A2 (es)
DE (1) DE60320439T2 (es)
EA (1) EA200500618A1 (es)
EC (1) ECSP055780A (es)
ES (1) ES2302938T3 (es)
IS (1) IS7751A (es)
MA (1) MA27452A1 (es)
MX (1) MXPA05003866A (es)
NO (1) NO20051406L (es)
OA (1) OA12938A (es)
PA (1) PA8586001A1 (es)
PE (1) PE20040775A1 (es)
PL (1) PL376396A1 (es)
TW (1) TW200424171A (es)
UY (1) UY28013A1 (es)
WO (1) WO2004032921A1 (es)

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TW200825084A (en) 2006-11-14 2008-06-16 Astrazeneca Ab New compounds 521
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WO2010150014A1 (en) 2009-06-24 2010-12-29 Pulmagen Therapeutics (Inflammation) Limited 5r- 5 -deuterated glitazones for respiratory disease treatment
JP5801997B2 (ja) 2009-07-07 2015-10-28 ファイザー・リミテッドＰｆｉｚｅｒ Ｌｉｍｉｔｅｄ 薬品の組合せを吸入するための投薬ユニット、投薬ユニットのパック、および吸入器
EP2813227A1 (en) 2009-10-22 2014-12-17 Vertex Pharmaceuticals Incorporated Compositions for treatment of cystic fibrosis and other chronic diseases
GB0918924D0 (en) 2009-10-28 2009-12-16 Vantia Ltd Azaindole derivatives
GB0918922D0 (en) 2009-10-28 2009-12-16 Vantia Ltd Aminopyridine derivatives
GB0918923D0 (en) 2009-10-28 2009-12-16 Vantia Ltd Aminothiazole derivatives
WO2011061527A1 (en) 2009-11-17 2011-05-26 Astrazeneca Ab Combinations comprising a glucocorticoid receptor modulator for the treatment of respiratory diseases
WO2011098746A1 (en) 2010-02-09 2011-08-18 Pulmagen Therapeutics (Inflammation) Limited Crystalline acid addition salts of ( 5r) -enanti0mer of pioglitazone
GB201002243D0 (en) 2010-02-10 2010-03-31 Argenta Therapeutics Ltd Respiratory disease treatment
GB201002224D0 (en) 2010-02-10 2010-03-31 Argenta Therapeutics Ltd Respiratory disease treatment
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WO2012034095A1 (en) 2010-09-09 2012-03-15 Irm Llc Compounds and compositions as trk inhibitors
US8372845B2 (en) 2010-09-17 2013-02-12 Novartis Ag Pyrazine derivatives as enac blockers
GB201016912D0 (en) 2010-10-07 2010-11-24 Astrazeneca Ab Novel combination
KR20140014184A (ko) 2011-02-25 2014-02-05 아이알엠 엘엘씨 Trk 억제제로서의 화합물 및 조성물
AR085509A1 (es) 2011-03-09 2013-10-09 Bayer Cropscience Ag Indol- y bencimidazolcarboxamidas como insecticidas y acaricidas
EA022342B1 (ru) 2011-06-10 2015-12-30 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Соединения с активностью антагонистов мускариновых рецепторов и агонистов адренергического рецептора бета2
US8883819B2 (en) 2011-09-01 2014-11-11 Irm Llc Bicyclic heterocycle derivatives for the treatment of pulmonary arterial hypertension
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Also Published As

Publication number Publication date
PE20040775A1 (es) 2004-12-10
BR0315234A (pt) 2005-08-23
AU2003269316A1 (en) 2004-05-04
KR20050047552A (ko) 2005-05-20
JP4490911B2 (ja) 2010-06-30
IS7751A (is) 2005-03-17
PL376396A1 (en) 2005-12-27
EA200500618A1 (ru) 2005-12-29
PA8586001A1 (es) 2005-02-04
DE60320439T2 (de) 2009-05-20
MA27452A1 (fr) 2005-07-01
AP2005003283A0 (en) 2005-06-30
DE60320439D1 (de) 2008-05-29
MXPA05003866A (es) 2005-06-22
EP1556034A1 (en) 2005-07-27
ES2302938T3 (es) 2008-08-01
UY28013A1 (es) 2004-04-30
AR041566A1 (es) 2005-05-18
NO20051406L (no) 2005-04-22
JP2006511596A (ja) 2006-04-06
CA2499314A1 (en) 2004-04-22
CO5550421A2 (es) 2005-08-31
EP1556034B1 (en) 2008-04-16
OA12938A (en) 2006-10-13
CA2499314C (en) 2010-08-24
WO2004032921A1 (en) 2004-04-22
ATE392206T1 (de) 2008-05-15
TW200424171A (en) 2004-11-16

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