ECSP056029A - Formulación para un inhalador con dosis medida que emplea hidrofluoroalcanos como propulsores - Google Patents

Formulación para un inhalador con dosis medida que emplea hidrofluoroalcanos como propulsores

Info

Publication number
ECSP056029A
ECSP056029A EC2005006029A ECSP056029A ECSP056029A EC SP056029 A ECSP056029 A EC SP056029A EC 2005006029 A EC2005006029 A EC 2005006029A EC SP056029 A ECSP056029 A EC SP056029A EC SP056029 A ECSP056029 A EC SP056029A
Authority
EC
Ecuador
Prior art keywords
formulation
inhaler
hydrofluoroalcans
propulsors
dose measurement
Prior art date
Application number
EC2005006029A
Other languages
English (en)
Inventor
George Destefano
Linda Jean Kelash-Cannavo
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of ECSP056029A publication Critical patent/ECSP056029A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

Se describe una formulación en suspensión mejorada para uso en un inhalador con dosis medida que tiene un propulsor de hidrofluoroalcano, en donde la mejora consiste en la adición controlada de una pequeña cantidad de agua.
EC2005006029A 2003-03-20 2005-09-20 Formulación para un inhalador con dosis medida que emplea hidrofluoroalcanos como propulsores ECSP056029A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45611303P 2003-03-20 2003-03-20

Publications (1)

Publication Number Publication Date
ECSP056029A true ECSP056029A (es) 2006-01-27

Family

ID=33098086

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2005006029A ECSP056029A (es) 2003-03-20 2005-09-20 Formulación para un inhalador con dosis medida que emplea hidrofluoroalcanos como propulsores

Country Status (28)

Country Link
US (1) US7914770B2 (es)
EP (1) EP1608336B1 (es)
JP (1) JP4708332B2 (es)
KR (1) KR101113003B1 (es)
CN (1) CN1761455A (es)
AT (1) ATE390125T1 (es)
AU (1) AU2004224367B2 (es)
BR (1) BRPI0408547A (es)
CA (1) CA2519523C (es)
CO (1) CO5640070A2 (es)
CY (1) CY1108137T1 (es)
DE (1) DE602004012718T2 (es)
DK (1) DK1608336T3 (es)
EA (1) EA009087B1 (es)
EC (1) ECSP056029A (es)
ES (1) ES2304616T3 (es)
HR (1) HRP20050822B1 (es)
ME (1) ME00420B (es)
MX (1) MXPA05009920A (es)
NO (1) NO336457B1 (es)
NZ (1) NZ542957A (es)
PL (1) PL1608336T3 (es)
PT (1) PT1608336E (es)
RS (1) RS51663B (es)
SI (1) SI1608336T1 (es)
UA (1) UA89751C2 (es)
WO (1) WO2004084858A2 (es)
ZA (1) ZA200506463B (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004011381A1 (de) * 2004-03-05 2005-09-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Impaktionsdüse für treibgasbetriebene Dosieraerosole
BRPI0512878A (pt) 2004-07-02 2008-04-15 Boehringer Ingelheim Int formulações de suspensão de aerossol, com tg 227 ea ou tg 134 a como agente propulsor
US20060140873A1 (en) * 2004-12-27 2006-06-29 Chang Heng W Aerosol pharmaceutical compositions
GB0501956D0 (en) * 2005-01-31 2005-03-09 Arrow Internat Nebulizer formulation
GB0518769D0 (en) * 2005-09-14 2005-10-19 Medpharm Ltd Topical formulations
DE102006053374A1 (de) * 2006-02-09 2007-08-16 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmazeutische Formulierung für Aerosole mit zwei oder mehr Wirkstoffen und mindestens einer oberflächenaktiven Substanz
DE102006014433A1 (de) 2006-03-27 2007-10-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Dosieraerosole für die Verabreichung von pharmazeutischen Zubereitungen
DE102006017320A1 (de) 2006-04-11 2007-10-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolsuspensionsformulierungen mit TG 227 ea oder TG 134 a als Treibmittel
WO2008047239A2 (en) * 2006-09-21 2008-04-24 Medispray Laboratories Pvt. Ltd. Stable aerosol pharmaceutical formulations
US20090048296A1 (en) * 2007-08-17 2009-02-19 Arcion Therapeutics, Inc. High concentration local anesthetic formulations
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
US8119694B2 (en) 2008-08-15 2012-02-21 Arcion Therapeutics, Inc. High concentration local anesthetic formulations
EP2414560B1 (de) 2009-03-31 2013-10-23 Boehringer Ingelheim International GmbH Verfahren zur beschichtung einer oberfläche eines bauteils
EP2432531B1 (de) 2009-05-18 2019-03-06 Boehringer Ingelheim International GmbH Adapter, inhalationseinrichtung und zerstäuber
US10016568B2 (en) 2009-11-25 2018-07-10 Boehringer Ingelheim International Gmbh Nebulizer
WO2011064163A1 (en) 2009-11-25 2011-06-03 Boehringer Ingelheim International Gmbh Nebulizer
MX2012005961A (es) 2009-11-25 2012-06-14 Boehringer Ingelheim Int Nebulizador.
EP2585151B1 (en) 2010-06-24 2018-04-04 Boehringer Ingelheim International GmbH Nebulizer
US20120204871A1 (en) * 2011-02-10 2012-08-16 Julio Cesar Vega Stable, non-corrosive formulations for pressurized metered dose inhalers
WO2012130757A1 (de) 2011-04-01 2012-10-04 Boehringer Ingelheim International Gmbh Medizinisches gerät mit behälter
US9827384B2 (en) 2011-05-23 2017-11-28 Boehringer Ingelheim International Gmbh Nebulizer
WO2013152894A1 (de) 2012-04-13 2013-10-17 Boehringer Ingelheim International Gmbh Zerstäuber mit kodiermitteln
CN102798044B (zh) * 2012-08-02 2014-09-10 深圳市华星光电技术有限公司 侧入式背光模组
EP2835146B1 (en) 2013-08-09 2020-09-30 Boehringer Ingelheim International GmbH Nebulizer
JP6643231B2 (ja) 2013-08-09 2020-02-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ネブライザ
US10722666B2 (en) 2014-05-07 2020-07-28 Boehringer Ingelheim International Gmbh Nebulizer with axially movable and lockable container and indicator
HUE058904T2 (hu) 2014-05-07 2022-09-28 Boehringer Ingelheim Int Porlasztókészülék
CA2948071C (en) 2014-05-07 2022-08-30 Boehringer Ingelheim International Gmbh Container, nebulizer and use
WO2016164508A1 (en) * 2015-04-10 2016-10-13 3M Innovative Properties Company Formulation and aerosol canisters, inhalers, and the like containing the formulation
GB2573297A (en) * 2018-04-30 2019-11-06 Mexichem Fluor Sa De Cv Pharmaceutical composition
WO2021216779A1 (en) * 2020-04-21 2021-10-28 Amphastar Pharmaceuticals, Inc. Anti-viral pharmaceutical formulations administered via devices for lung targeted delivery

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405598A (en) * 1976-01-30 1983-09-20 Fisons, Limited Composition for treating asthma
GB8824804D0 (en) 1988-10-22 1988-11-30 Fisons Plc Device
US5225183A (en) 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
US5919435A (en) 1990-11-09 1999-07-06 Glaxo Group Limited Aerosol formulation containing a particulate medicament
GB9202519D0 (en) * 1992-02-06 1992-03-25 Glaxo Group Ltd Medicaments
ES2129117T3 (es) * 1992-12-09 1999-06-01 Boehringer Ingelheim Pharma Formulaciones en disolucion en forma de aerosol medicinales estabilizadas.
CA2161632C (en) 1993-04-30 1999-08-10 Todd D. Alband Seal configuration for aerosol canister
EP0708805B9 (en) 1993-07-15 2012-03-21 Minnesota Mining And Manufacturing Company Seals for use in an aerosol delivery device
CA2218179A1 (en) * 1995-04-14 1996-10-17 Glaxo Wellcome Inc. Metered dose inhaler for beclomethasone dipropionate
GB9513084D0 (en) 1995-06-27 1995-08-30 Bespak Plc Dispensing apparatus
SE9701750D0 (sv) 1997-05-12 1997-05-12 Astra Pharma Prod Inhalation device and method of manufacture thereof
GB2326334A (en) 1997-06-13 1998-12-23 Chiesi Farma Spa Pharmaceutical aerosol compositions
US20010031244A1 (en) 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
US6423298B2 (en) * 1998-06-18 2002-07-23 Boehringer Ingelheim Pharmaceuticals, Inc. Pharmaceutical formulations for aerosols with two or more active substances
ATE234604T1 (de) * 1998-08-04 2003-04-15 Jago Res Ag Medizinische aerosolformulierungen
IT1303788B1 (it) 1998-11-25 2001-02-23 Chiesi Farma Spa Formulazioni di aerosol medicinali.
DZ2947A1 (fr) 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
US6261539B1 (en) * 1998-12-10 2001-07-17 Akwete Adjei Medicinal aerosol formulation
US7074388B2 (en) * 1998-12-10 2006-07-11 Kos Life Science, Inc. Water stabilized medicinal aerosol formulation
US20030008369A1 (en) * 1999-03-03 2003-01-09 Board Of Regents, The University Of Texas System Genetic and epigenetic manipulation of ABC transporters and ecto-phosphatases
GB0002798D0 (en) 2000-02-09 2000-03-29 Glaxo Group Ltd Actuator nozzle for metered dose inhaler
EP1241113A1 (en) 2001-03-12 2002-09-18 CHIESI FARMACEUTICI S.p.A. Inhaler with means for improving chemical stability of medicinal aerosol solution contained therein
CA2452140C (en) 2001-06-26 2010-12-14 Norton Healthcare, Ltd. An improved aerosol actuator

Also Published As

Publication number Publication date
AU2004224367B2 (en) 2009-10-08
MXPA05009920A (es) 2005-11-04
WO2004084858A3 (en) 2004-11-04
NO336457B1 (no) 2015-08-31
WO2004084858A2 (en) 2004-10-07
JP2006520797A (ja) 2006-09-14
NZ542957A (en) 2008-09-26
DK1608336T3 (da) 2008-06-02
NO20054839L (no) 2005-10-19
BRPI0408547A (pt) 2006-03-07
EA200501363A1 (ru) 2006-04-28
KR20050111382A (ko) 2005-11-24
UA89751C2 (ru) 2010-03-10
CA2519523A1 (en) 2004-10-07
PT1608336E (pt) 2008-04-21
US7914770B2 (en) 2011-03-29
DE602004012718T2 (de) 2009-05-07
PL1608336T3 (pl) 2008-09-30
SI1608336T1 (sl) 2008-08-31
EP1608336A2 (en) 2005-12-28
CY1108137T1 (el) 2014-02-12
EP1608336B1 (en) 2008-03-26
CO5640070A2 (es) 2006-05-31
HRP20050822A2 (en) 2006-10-31
ES2304616T3 (es) 2008-10-16
EA009087B1 (ru) 2007-10-26
ATE390125T1 (de) 2008-04-15
DE602004012718D1 (de) 2008-05-08
AU2004224367A1 (en) 2004-10-07
CA2519523C (en) 2012-03-13
JP4708332B2 (ja) 2011-06-22
CN1761455A (zh) 2006-04-19
RS20050705A (sr) 2008-04-04
RS51663B (sr) 2011-10-31
ZA200506463B (en) 2006-04-26
ME00420B (me) 2011-12-20
US20040184994A1 (en) 2004-09-23
HRP20050822B1 (hr) 2013-09-30
KR101113003B1 (ko) 2012-02-24

Similar Documents

Publication Publication Date Title
CO5640070A2 (es) Formulacion para un inhalador con dosis medida que emplea hidrofluoroalcanos como propulsores
CL2012003625A1 (es) Una composicion acuosa que contiene bromhexina, en donde la composicion tiene una cantidad de azucar-alcoholes inferior a 10 g referida a 100 ml de la composicion; y su uso para la terapia secretorica en enfermedades broncopulmonares agudas y cronicas.
UY30314A1 (es) Derivados de benzonitrilo sustituidos con glucopiranosilo, composiciones farmacéuticas que contienen compuestos de este tipo, su uso y procedimiento para su fabricacion
CR10088A (es) Compuestos de piperazina con accion herbicida
AR110174A2 (es) Agentes endoparasiticidas y procedimiento de preparación
CR11167A (es) Uso de homo y copolimeros para la estabilizacion de formulaciones de principios activos
CL2008001951A1 (es) Compuestos derivados de imidazo[1,2-a]pirimidin-2-ilmetil sustituidos; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el trastorno del sueno, depresion, ansiedad, trastorno relacionado con el abuso de sustancias, entre otras.
ECSP045491A (es) Nueva sal formiato de o-desmetil venlafaxina
MX2020011339A (es) Polímero catiónico y uso para suministro de biomolecúla.
PA8577201A1 (es) 3-fenil-propionamido, 3-fenil-acrilamido y derivados 3-fenil-propinamido como inhibidores de mao-b
CO2022009510A2 (es) Compuestos activos frente a receptores nucleares
CL2009000665A1 (es) Compuestos derivados de pirrolidinilo; composicion farmaceutica que comprende a dichos compuestos; y su uso en el tratamiento de la ansiedad, depresion o ambas.
MX2021008308A (es) 3compuestos de fenilamidina 3-sustituida, preparacion y uso.
BR112015030273A2 (pt) camada do corpo de tubo flexível e método de produção do mesmo
AR072426A1 (es) Uso de nifurtimox para el tratamiento de enfermedades causadas por tricomonadida
ECSP034570A (es) Formulacion de una solucion de inhalacion con una sal tiotropio
MX2021000771A (es) Formulacion aerosolizable.
ECSP034541A (es) Formulacion de una solucion de inhalacion con una sal tiotropio
BR112012018427A8 (pt) Uso de composto, e, método para aumentar o ph de uma suspensão aquosa
BR0307379A (pt) Aminas substituìdas como inibidores de ige
MX342968B (es) Composiciones de dibromomalonamida y su uso como biocida.
ECSP034463A (es) Composicion farmaceutica
CL2008001722A1 (es) Compuestos derivados de heterociclos; agente que contiene a dichos compuestos, diluyentes y/o sustancias tensoactivas; procedimiento para combatir organismos nocivos; y uso de dichos compuestos para combatir organismos nocivos.
BRPI0803040A2 (pt) sistema de estêncil, e, método para usar um sistema de estêncil