ECSP066761A - Moduladores de receptores de androgenos - Google Patents

Moduladores de receptores de androgenos

Info

Publication number
ECSP066761A
ECSP066761A EC2006006761A ECSP066761A ECSP066761A EC SP066761 A ECSP066761 A EC SP066761A EC 2006006761 A EC2006006761 A EC 2006006761A EC SP066761 A ECSP066761 A EC SP066761A EC SP066761 A ECSP066761 A EC SP066761A
Authority
EC
Ecuador
Prior art keywords
androgen
receiver modulators
modulators
androgen receiver
benzonitriles
Prior art date
Application number
EC2006006761A
Other languages
English (en)
Inventor
Bruce Allen Lefker
Lain-Yen Hu
Huangshu Lei
Daniel Yunlong Du
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of ECSP066761A publication Critical patent/ECSP066761A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invención se refiere a una nueva clase de 4-oxo-benzonitrilos, a su uso como moduladores de andrógenos y a su uso en el tratamiento de la alopecia
EC2006006761A 2004-02-13 2006-08-09 Moduladores de receptores de androgenos ECSP066761A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54473804P 2004-02-13 2004-02-13
US60564704P 2004-08-30 2004-08-30

Publications (1)

Publication Number Publication Date
ECSP066761A true ECSP066761A (es) 2006-11-16

Family

ID=34890476

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2006006761A ECSP066761A (es) 2004-02-13 2006-08-09 Moduladores de receptores de androgenos

Country Status (20)

Country Link
US (1) US7576128B2 (es)
EP (1) EP1716110A1 (es)
JP (1) JP3997255B2 (es)
KR (1) KR100783255B1 (es)
AP (1) AP2006003700A0 (es)
AR (1) AR047606A1 (es)
AU (1) AU2005214167B2 (es)
BR (1) BRPI0507670A (es)
CA (1) CA2554696C (es)
CR (1) CR8555A (es)
EA (1) EA009902B1 (es)
EC (1) ECSP066761A (es)
IL (1) IL176935A0 (es)
MA (1) MA28361A1 (es)
NO (1) NO20064053L (es)
PA (1) PA8623501A1 (es)
PE (1) PE20051168A1 (es)
TW (1) TW200534842A (es)
UY (1) UY28746A1 (es)
WO (1) WO2005080320A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005214167B2 (en) 2004-02-13 2008-08-07 Warner-Lambert Company Llc Androgen receptor modulators
CA2563291A1 (en) 2004-04-13 2005-10-27 Warner-Lambert Company Llc 4-cyano-phenoxy-alkyl carboxyl derivatives as androgen modulators
BRPI0509980A (pt) 2004-04-22 2007-10-16 Warner Lambert Co moduladores de androgênio
BRPI0513020A (pt) 2004-07-08 2008-04-22 Warner Lambert Co moduladores de andrÈgenio, seus usos, composição farmacêutica, formulação farmacêutica tópica e artigo de fabricação
BRPI0514469A (pt) * 2004-08-18 2008-06-10 Warner Lambert Co moduladores de androgênio
ATE392419T1 (de) * 2004-08-31 2008-05-15 Warner Lambert Co Androgenmodulatoren
TW200724139A (en) 2005-05-05 2007-07-01 Warner Lambert Co Androgen modulators
TW200708499A (en) * 2005-06-22 2007-03-01 Warner Lambert Co Process for producing ethers
WO2007007149A1 (en) * 2005-07-12 2007-01-18 Warner-Lambert Company Llc Androgen modulators
US20090170886A1 (en) * 2005-08-08 2009-07-02 Pfizer Inc Androgen modulators
EP3108879A1 (en) * 2015-06-25 2016-12-28 Cassiopea S.p.A. High concentration formulation
EP3833343B1 (en) * 2018-08-07 2024-02-21 Emory University Heterocyclic flavone derivatives, compositions, and methods related thereto

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Also Published As

Publication number Publication date
TW200534842A (en) 2005-11-01
BRPI0507670A (pt) 2007-07-17
PE20051168A1 (es) 2006-02-18
IL176935A0 (en) 2006-12-10
MA28361A1 (fr) 2006-12-01
PA8623501A1 (es) 2005-08-30
US7576128B2 (en) 2009-08-18
KR20060116223A (ko) 2006-11-14
US20050182132A1 (en) 2005-08-18
AU2005214167A1 (en) 2005-09-01
JP2007522199A (ja) 2007-08-09
CR8555A (es) 2006-10-17
CA2554696C (en) 2009-06-30
NO20064053L (no) 2006-11-08
AU2005214167B2 (en) 2008-08-07
AP2006003700A0 (en) 2006-08-31
UY28746A1 (es) 2005-09-30
AR047606A1 (es) 2006-01-25
EA009902B1 (ru) 2008-04-28
JP3997255B2 (ja) 2007-10-24
CA2554696A1 (en) 2005-09-01
EA200601267A1 (ru) 2006-12-29
EP1716110A1 (en) 2006-11-02
WO2005080320A1 (en) 2005-09-01
KR100783255B1 (ko) 2007-12-06

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